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D. Roderer · SciRah

Researcher profile · Semantic Scholar

D. Roderer

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D. Roderer — researcher profile on SciRah

h-index: 16
Works: 54
Citations: 1,912

Most-cited papers

SPHIRE-crYOLO is a fast and accurate fully automated particle picker for cryo-EM
T. Wagner, F. Merino, M. Stabrin, T. Moriya +15 more
2019Communications Biology1,034 citations Open access
Semantic Scholar
SPHIRE-crYOLO: A fast and well-centering automated particle picker for cryo-EM
T. Wagner, F. Merino, M. Stabrin, T. Moriya +15 more
2018bioRxiv227 citations Open access
Semantic Scholar
Membrane insertion of a Tc toxin in near-atomic detail
C. Gatsogiannis, F. Merino, Daniel Prumbaum, D. Roderer +3 more
2016Nature Structural &Molecular Biology94 citations
Semantic Scholar
The assembly dynamics of the cytolytic pore toxin ClyA
S. Benke, D. Roderer, Bengt Wunderlich, D. Nettels +2 more
2015Nature Communications89 citations Open access
Semantic Scholar
Tc Toxin Complexes: Assembly, Membrane Permeation, and Protein Translocation.
D. Roderer, S. Raunser
2019Annual Review of Microbiology45 citations
Semantic Scholar
Tc toxin activation requires unfolding and refolding of a β-propeller
C. Gatsogiannis, F. Merino, D. Roderer, D. Balchin +4 more
2018Nature43 citations
Semantic Scholar
Structure of a Tc holotoxin pore provides insights into the translocation mechanism
D. Roderer, O. Hofnagel, R. Benz, S. Raunser
2019Proceedings of the National Academy of Sciences of the United States of America38 citations Open access
Semantic Scholar
Glycan-dependent cell adhesion mechanism of Tc toxins
D. Roderer, F. Bröcker, O. Sitsel, P. Kaplonek +3 more
2020Nature Communications35 citations Open access
Semantic Scholar
Common architecture of Tc toxins from human and insect pathogenic bacteria
F. Leidreiter, D. Roderer, D. Meusch, C. Gatsogiannis +2 more
2019Science Advances35 citations Open access
Semantic Scholar
Assembly mechanism of the α-pore–forming toxin cytolysin A from Escherichia coli
D. Roderer, R. Glockshuber
2017Philosophical Transactions of the Royal Society B: Biological Sciences34 citations Open access
Semantic Scholar
CRISPR screens in Drosophila cells identify Vsg as a Tc toxin receptor
Ying Xu, R. Viswanatha, O. Sitsel, D. Roderer +7 more
2022Nature32 citations Open access
Semantic Scholar
Towards the application of Tc toxins as a universal protein translocation system
D. Roderer, E. Schubert, O. Sitsel, S. Raunser
2019Nature Communications31 citations Open access
Semantic Scholar
Structural basis of Fusobacterium nucleatum adhesin Fap2 interaction with receptors on cancer and immune cells
Felix Schöpf, G. L. Marongiu, Klaudia Milaj, T. Sprink +3 more
2024bioRxiv28 citations Open access
Semantic Scholar
Acceleration of protein folding by four orders of magnitude through a single amino acid substitution
D. Roderer, Martin A. Schärer, Marina Rubini, R. Glockshuber
2015Scientific Reports24 citations Open access
Semantic Scholar
Mechanism of threonine ADP-ribosylation of F-actin by a Tc toxin
A. Belyy, Florian Lindemann, D. Roderer, J. Funk +5 more
2022Nature Communications20 citations Open access
Semantic Scholar
PTC3 holotoxin complex from Photorhabdus luminecens in prepore state (TcdA1, TcdB2, TccC3)
C. Gatsogiannis, F. Merino, D. Roderer, D. Balchin +4 more
201817 citations
Semantic Scholar
Characterization of variants of the pore-forming toxin ClyA from Escherichia coli controlled by a redox switch.
D. Roderer, S. Benke, M. Müller, Helene Fäh-Rechsteiner +3 more
2014Biochemistry16 citations Open access
Semantic Scholar
Acceleration of the Rate‐Limiting Step of Thioredoxin Folding by Replacement of its Conserved cis‐Proline with (4 S)‐Fluoroproline
D. Roderer, R. Glockshuber, Marina Rubini
2015ChemBioChem13 citations
Semantic Scholar
Multistate kinetics of the syringe-like injection mechanism of Tc toxins
P. Ng'ang'a, Julian Folz, Svetlana Kucher, D. Roderer +10 more
2024bioRxiv10 citations Open access
Semantic Scholar
Soluble Oligomers of the Pore-forming Toxin Cytolysin A from Escherichia coli Are Off-pathway Products of Pore Assembly*
D. Roderer, S. Benke, B. Schuler, R. Glockshuber
2016Journal of Biological Chemistry10 citations Open access
Semantic Scholar
Spatial N-glycan rearrangement on α5β1 integrin nucleates galectin-3 oligomers to determine endocytic fate
Massiullah Shafaq-Zadah, E. Dransart, Ilyes Hamitouche, C. Wunder +18 more
2025Nature Communications9 citations Open access
Semantic Scholar
Structural basis for immune cell binding of Fusobacterium nucleatum via the trimeric autotransporter adhesin CbpF
G. L. Marongiu, U. Fink, Felix Schöpf, Andreas Oder +2 more
2024bioRxiv8 citations Open access
Semantic Scholar
Spatial N-glycan rearrangement on α5β1 integrin nucleates galectin-3 oligomers to determine endocytic fate
Massiullah Shafaq-Zadah, E. Dransart, C. Wunder, Valérie Chambon +17 more
2023bioRxiv6 citations Open access
Semantic Scholar
Site‐specific N‐glycan profiles of α5β1 integrin from rat liver
Ekaterina Mirgorodskaya, E. Dransart, Massiullah Shafaq-Zadah, D. Roderer +3 more
2022Biology of the Cell5 citations Open access
Semantic Scholar
C. perfringens enterotoxin-claudin pore complex: Models for structure, mechanism of pore assembly and cation permeability
S. Nagarajan, J. Weber, D. Roderer, Jörg Piontek
2024bioRxiv4 citations Open access
Semantic Scholar
Nucleoside diphosphate kinase A (NME1) catalyses its own oligophosphorylation
Arif Celik, Felix Schöpf, Christian E. Stieger, Sarah Lampe +7 more
2025Nature Chemistry2 citations Open access
Semantic Scholar
Conserved architecture of Tc toxins from human and insect pathogenic bacteria
F. Leidreiter, D. Roderer, D. Meusch, C. Gatsogiannis +2 more
2019bioRxiv2 citations Open access
Semantic Scholar
Atomic structure and dynamics of the mechanosensitive channel MscL from E. coli by cryo-EM and solid-state NMR
Tao-Ran Xiao, Alexandra Kovinko, C. Shi, Henry Sawczyc +9 more
2026bioRxiv1 citations Open access
Semantic Scholar
Characterization of the Direct and Indirect Inhibition of Apoptosis by Full‐Length Recombinant Bcl‐xL Monomers
Christina Elsner, L. Epasto, Adeline Cieren, Dominik Gendreizig +3 more
2025bioRxiv1 citations Open access
Semantic Scholar
Structure of Photorhabdus luminescens Tc holotoxin pore, Mutation TccC3-D651A
D. Roderer, S. Raunser
20191 citations
Semantic Scholar
Atomic structure and plasticity of the CTX-MthK complex investigated by cryo-EM, NMR, and MD simulations
Denis Qoraj, Swantje Mohr, Y. K. Aldakul, T. Sprink +9 more
2026bioRxiv0 citations Open access
Semantic Scholar
The role of adhesins of Fusobacterium nucleatum in colorectal cancer – a structural perspective
Felix Schöpf, G. L. Marongiu, D. Roderer
2026Gut microbes0 citations Open access
Semantic Scholar
Atomic structure and dynamics of the mechanosensitive channel MscL from Escherichia coli by cryo-EM and solid-state NMR
Tao-Ran Xiao, Alexandra Kovinko, C. Shi, Henry Sawczyc +10 more
2026Science Advances0 citations Open access
Semantic Scholar
Nucleoside diphosphate kinase A (NME1) catalyzes its own oligophosphorylation
Arif Celik, Felix Schöpf, Christian E. Stieger, J. Morgan +6 more
2024bioRxiv0 citations
Semantic Scholar
Structural basis of rhomboid protease substrate recognition and transmembrane helix arrangement by cryo-EM and integrative modeling
Co-supervisor, D. Roderer, Pharmakologie Fmp, A. Lange +1 more
20220 citations
Semantic Scholar
Xenorhabdus nematophila XptA1 in complex with porcine mucosa heparin
D. Roderer, F. Broecker, O. Sitsel, P. Kaplonek +3 more
20200 citations
Semantic Scholar
Unveiling the pH-Dependent Dynamics of the Prepore-to-Pore Transition of a Tc Toxin
S. Kucher, D. Roderer, T. Assafa, S. Raunser +1 more
20200 citations Open access
Semantic Scholar
Morganella morganii TcdA4 in complex with porcine mucosa heparin
D. Roderer, F. Broecker, O. Sitsel, P. Kaplonek +3 more
20200 citations
Semantic Scholar
Cryo-EM structure of Xenorhabdus nematophila XptA1
D. Roderer, F. Leidreiter, C. Gatsogiannis, D. Meusch +2 more
20190 citations
Semantic Scholar
Cryo-EM structure of Morganella morganii TcdA4
D. Roderer, F. Leidreiter, C. Gatsogiannis, D. Meusch +2 more
20190 citations
Semantic Scholar
Cryo-EM structure of Yersinia pseudotuberculosis TcaA-TcaB
D. Roderer, F. Leidreiter, C. Gatsogiannis, D. Meusch +2 more
20190 citations
Semantic Scholar
Cryo-EM structure of Photorhabdus luminescens TcdA4
D. Roderer, F. Leidreiter, C. Gatsogiannis, D. Meusch +2 more
20190 citations
Semantic Scholar
Crystal Structure of TcdB2-TccC3-Cdc42
D. Roderer, E. Schubert, O. Sitsel, S. Raunser
20190 citations
Semantic Scholar
Crystal Structure of TcdB2-TccC3-TEV
D. Roderer, E. Schubert, O. Sitsel, S. Raunser
20190 citations
Semantic Scholar
Glycan-dependent two-step cell adhesion mechanism of Tc toxins
D. Roderer, F. Bröcker, O. Sitsel, P. Kaplonek +3 more
2019bioRxiv0 citations Open access
Semantic Scholar
Cryo-EM structure of Photorhabdus luminescens TcdA1
D. Roderer, F. Leidreiter, C. Gatsogiannis, D. Meusch +2 more
20190 citations
Semantic Scholar
PTC3 holotoxin complex from Photorhabdus luminiscens - Mutant TcC-D651A
C. Gatsogiannis, F. Merino, D. Roderer, David Balchin +4 more
20180 citations
Semantic Scholar
Crystal Structure of TcdB2-TccC3 without hypervariable C-terminal region
C. Gatsogiannis, F. Merino, D. Roderer, D. Balchin +4 more
20180 citations
Semantic Scholar
Cryo-EM structure of the Tc toxin TcdA1 in its pore state
C. Gatsogiannis, F. Merino, Daniel Prumbaum, D. Roderer +3 more
20160 citations
Semantic Scholar
Cryo-EM structure of the Tc toxin TcdA1 in its pore state (obtained by flexible fitting)
C. Gatsogiannis, F. Merino, D. Prumbaum, D. Roderer +3 more
20160 citations
Semantic Scholar

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