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F. Merino · SciRah

Researcher profile · Semantic Scholar

F. Merino

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F. Merino — researcher profile on SciRah

h-index: 24
Works: 74
Citations: 3,027

Most-cited papers

SPHIRE-crYOLO is a fast and accurate fully automated particle picker for cryo-EM
T. Wagner, F. Merino, M. Stabrin, T. Moriya +15 more
2019Communications Biology1,034 citations Open access
Semantic Scholar
SPHIRE-crYOLO: A fast and well-centering automated particle picker for cryo-EM
T. Wagner, F. Merino, M. Stabrin, T. Moriya +15 more
2018bioRxiv227 citations Open access
Semantic Scholar
Structural transitions of F-actin upon ATP hydrolysis at near-atomic resolution revealed by cryo-EM
F. Merino, S. Pospich, J. Funk, T. Wagner +4 more
2018Nature Structural & Molecular Biology174 citations
Semantic Scholar
High-resolution Single Particle Analysis from Electron Cryo-microscopy Images Using SPHIRE
T. Moriya, Michael Saur, M. Stabrin, F. Merino +5 more
2017Journal of Visualized Experiments169 citations Open access
Semantic Scholar
OCT4: dynamic DNA binding pioneers stem cell pluripotency.
S. Jerabek, F. Merino, H. Schöler, V. Cojocaru
2014Biochimica et Biophysica Acta156 citations
Semantic Scholar
Structural effects and functional implications of phalloidin and jasplakinolide binding to actin filaments
S. Pospich, F. Merino, S. Raunser
2019bioRxiv104 citations Open access
Semantic Scholar
Electron cryo-microscopy structure of the canonical TRPC4 ion channel
D. Vinayagam, T. Mager, Amir Apelbaum, Arne Bothe +4 more
2018bioRxiv100 citations Open access
Semantic Scholar
Profilin and formin constitute a pacemaker system for robust actin filament growth
J. Funk, F. Merino, L. Venkova, L. Heydenreich +5 more
2019bioRxiv94 citations Open access
Semantic Scholar
Membrane insertion of a Tc toxin in near-atomic detail
C. Gatsogiannis, F. Merino, Daniel Prumbaum, D. Roderer +3 more
2016Nature Structural &Molecular Biology94 citations
Semantic Scholar
Towards a structural understanding of the remodeling of the actin cytoskeleton
F. Merino, S. Pospich, S. Raunser
2019Seminars in Cell and Developmental Biology83 citations Open access
Semantic Scholar
Cryo-EM structure of the ClpXP protein degradation machinery
C. Gatsogiannis, Dóra Balogh, F. Merino, S. Sieber +1 more
2019Nature Structural & Molecular Biology82 citations Open access
Semantic Scholar
A barbed end interference mechanism reveals how capping protein promotes nucleation in branched actin networks
J. Funk, F. Merino, M. Schaks, K. Rottner +2 more
2021Nature Communications80 citations Open access
Semantic Scholar
Structure of the Lifeact–F-actin complex
A. Belyy, F. Merino, O. Sitsel, S. Raunser
2020bioRxiv60 citations Open access
Semantic Scholar
Structural basis of TRPC4 regulation by calmodulin and pharmacological agents
D. Vinayagam, D. Quentin, J. Yu-Strzelczyk, O. Sitsel +8 more
2020bioRxiv58 citations Open access
Semantic Scholar
The ADP‐dependent sugar kinase family: Kinetic and evolutionary aspects
V. Guixé, F. Merino
2009IUBMB Life - A Journal of the International Union of Biochemistry and Molecular Biology52 citations Open access
Semantic Scholar
Structural basis for the SOX-dependent genomic redistribution of OCT4 in stem cell differentiation.
F. Merino, C. Ng, Veeramohan Veerapandian, H. Schöler +2 more
2014Structure48 citations Open access
Semantic Scholar
The breakthrough in protein structure prediction
A. Lupas, J. Pereira, V. Alva, F. Merino +2 more
2021Biochemical Journal45 citations Open access
Semantic Scholar
Tc toxin activation requires unfolding and refolding of a β-propeller
C. Gatsogiannis, F. Merino, D. Roderer, D. Balchin +4 more
2018Nature43 citations
Semantic Scholar
Exploring protein-protein interactions at the proteome level.
Hadeer Elhabashy, F. Merino, V. Alva, O. Kohlbacher +1 more
2022Structure40 citations Open access
Semantic Scholar
Structure of the RZZ complex and molecular basis of Spindly‐driven corona assembly at human kinetochores
T. Raisch, G. Ciossani, Ennio A. d’Amico, Verena Cmentowski +7 more
2021bioRxiv34 citations Open access
Semantic Scholar
Electron Cryo-microscopy as a Tool for Structure-Based Drug Development.
F. Merino, S. Raunser
2017Angewandte Chemie32 citations
Semantic Scholar
Cooperative DNA Recognition Modulated by an Interplay between Protein-Protein Interactions and DNA-Mediated Allostery
F. Merino, B. Bouvier, V. Cojocaru
2015PLoS Comput. Biol.30 citations Open access
Semantic Scholar
ADP-dependent 6-Phosphofructokinase from Pyrococcus horikoshii OT3
M. Currie, F. Merino, T. Skarina, A. Wong +7 more
2009Journal of Biological Chemistry28 citations Open access
Semantic Scholar
Reconstructed ancestral enzymes reveal that negative selection drove the evolution of substrate specificity in ADP-dependent kinases
V. Castro-Fernández, A. Herrera-Morandé, Ricardo A. Zamora, F. Merino +6 more
2017Journal of Biological Chemistry24 citations Open access
Semantic Scholar
A new method for determining the Michaelis constant.
F. Merino
197422 citations Open access
Semantic Scholar
Mechanism of actin-dependent activation of nucleotidyl cyclase toxins from bacterial human pathogens
A. Belyy, F. Merino, U. Mechold, S. Raunser
2021Nature Communications21 citations Open access
Semantic Scholar
Specificity evolution of the ADP‐dependent sugar kinase family –in silico studies of the glucokinase/phosphofructokinase bifunctional enzyme from Methanocaldococcus jannaschii
F. Merino, V. Guixé
2008The FEBS Journal19 citations Open access
Semantic Scholar
PTC3 holotoxin complex from Photorhabdus luminecens in prepore state (TcdA1, TcdB2, TccC3)
C. Gatsogiannis, F. Merino, D. Roderer, D. Balchin +4 more
201817 citations
Semantic Scholar
Catalytic and regulatory roles of divalent metal cations on the phosphoryl-transfer mechanism of ADP-dependent sugar kinases from hyperthermophilic archaea.
F. Merino, J. A. Rivas-Pardo, A. Caniuguir, Ivonne García +1 more
2012Biochimie15 citations Open access
Semantic Scholar
Protein topology determines substrate-binding mechanism in homologous enzymes.
A. Herrera-Morandé, V. Castro-Fernández, F. Merino, Cesar A. Ramírez-Sarmiento +3 more
2018Biochimica et Biophysica Acta - General Subjects8 citations Open access
Semantic Scholar
Uncoupling the MgATP‐induced inhibition and aggregation of Escherichia coli phosphofructokinase‐2 by C‐terminal mutations
M. Báez, F. Merino, G. Astorga, J. Babul
2008FEBS Letters8 citations Open access
Semantic Scholar
Reconstructed ancestral enzymes reveal that negative selection drove the evolution of substrate specificity in ADP-dependent kinases.
V. Castro-Fernández, A. Herrera-Morandé, Ricardo A. Zamora, F. Merino +6 more
2017Journal of Biological Chemistry7 citations Open access
Semantic Scholar
Kryo‐Elektronenmikroskopie als Methode für die strukturbasierte Wirkstoffentwicklung
F. Merino, Stefan Raunser
20176 citations
Semantic Scholar
The bigger picture: global analysis of solubilization performance of classical detergents versus new synthetic polymers utilizing shotgun proteomics
Stefan Mueller, J. Kubíček, F. Merino, Philipp T. Hanisch +2 more
2023bioRxiv5 citations Open access
Semantic Scholar
The mother of all actins?
F. Merino, S. Raunser
2016eLife5 citations Open access
Semantic Scholar
On the Specialization History of the ADP-Dependent Sugar Kinase Family
F. Merino, V. Guixé
20114 citations Open access
Semantic Scholar
ADP-dependent 6-Phosphofructokinase from Pyrococcus horikoshii OT 3 STRUCTURE
M. Currie, F. Merino, T. Skarina, A. Wong +7 more
20092 citations
Semantic Scholar
A structure-derived mechanism reveals how capping protein promotes nucleation in branched actin networks
J. Funk, F. Merino, M. Schaks, K. Rottner +2 more
2021bioRxiv1 citations Open access
Semantic Scholar
The complex simplicity of the bacterial cytoskeleton
F. Merino, S. Raunser
2018Proceedings of the National Academy of Sciences of the United States of America1 citations Open access
Semantic Scholar
A genetic algorithm framework for algorithmic design through logic circuit optimization
F. Merino, Daniel Cabarcas
2025SeMA Journal0 citations Open access
Semantic Scholar
Structure of the P. aeruginosa ExoY-F-actin complex
A. Belyy, F. Merino, S. Raunser
20210 citations
Semantic Scholar
Structure of the V. vulnificus ExoY-G-actin-profilin complex
A. Belyy, F. Merino, S. Raunser
20210 citations
Semantic Scholar
Structure of capping protein bound to the barbed end of a cytoplasmic actin filament
J. Funk, F. Merino, M. Schacks, K. Rottner +2 more
20210 citations
Semantic Scholar
Cryo-EM structure of phalloidin-stabilized F-actin (copolymerized)
S. Pospich, F. Merino, S. Raunser
20200 citations
Semantic Scholar
TRPC4 in complex with inhibitor GFB-8438
D. Vinayagam, D. Quentin, O. Sistel, F. Merino +5 more
20200 citations
Semantic Scholar
TRPC4 in complex with inhibitor GFB-8749
D. Vinayagam, D. Quentin, O. Sistel, F. Merino +5 more
20200 citations
Semantic Scholar
TRPC4 in LMNG detergent
D. Vinayagam, D. Quentin, O. Sistel, F. Merino +5 more
20200 citations
Semantic Scholar
Cryo-EM structure of phalloidin-stabilized F-actin (aged)
S. Pospich, F. Merino, S. Raunser
20200 citations
Semantic Scholar
Author response: Structural basis of TRPC4 regulation by calmodulin and pharmacological agents
D. Vinayagam, D. Quentin, J. Yu-Strzelczyk, O. Sitsel +8 more
20200 citations Open access
Semantic Scholar
TRPC4 in complex with inhibitor GFB-9289
D. Vinayagam, D. Quentin, O. Sistel, F. Merino +5 more
20200 citations
Semantic Scholar

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S. Raunser×31
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M. Stabrin×9
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M. Stabrin — researcher profile on SciRah
V. Guixé×9
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D. Quentin×8
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C. Gatsogiannis

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D. Vinayagam×7

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