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P. Gerwins · SciRah

Researcher profile · Semantic Scholar

P. Gerwins

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P. Gerwins — researcher profile on SciRah

h-index: 31
Works: 85
Citations: 4,306

Most-cited papers

Common and distinct intracellular signaling pathways in human neutrophils utilized by platelet activating factor and FMLP.
J. Nick, N. Avdi, S. Young, C. Knall +3 more
1997Journal of Clinical Investigation354 citations Open access
Semantic Scholar
MEKKs, GCKs, MLKs, PAKs, TAKs, and tpls: upstream regulators of the c-Jun amino-terminal kinases?
G. Fanger, P. Gerwins, C. Widmann, M. Jarpe +1 more
1997Current Opinion in Genetics and Development335 citations
Semantic Scholar
Function of fibroblast growth factors and vascular endothelial growth factors and their receptors in angiogenesis.
P. Gerwins, E. Sköldenberg, L. Claesson-Welsh
2000Critical reviews in oncology/hematology302 citations
Semantic Scholar
Cloning of a Novel Mitogen-activated Protein Kinase Kinase Kinase, MEKK4, That Selectively Regulates the c-Jun Amino Terminal Kinase Pathway*
P. Gerwins, L. Jonathan, G. Johnson
1997Journal of Biological Chemistry254 citations Open access
Semantic Scholar
Molecular Cloning of Mitogen-activated Protein/ERK Kinase Kinases (MEKK) 2 and 3
J. Blank, P. Gerwins, E. M. Elliott, S. Sather +1 more
1996Journal of Biological Chemistry254 citations Open access
Semantic Scholar
MEK Kinase 1, a Substrate for DEVD-Directed Caspases, Is Involved in Genotoxin-Induced Apoptosis
C. Widmann, P. Gerwins, N. L. Johnson, M. Jarpe +1 more
1998Molecular and Cellular Biology249 citations Open access
Semantic Scholar
Biomechanical regulation of blood vessel growth during tissue vascularization
W. Kilarski, B. Samolov, Ludvig Petersson, A. Kvanta +1 more
2009Nature Medicine241 citations Open access
Semantic Scholar
p38 MAP kinase negatively regulates endothelial cell survival, proliferation, and differentiation in FGF-2–stimulated angiogenesis
Taro Matsumoto, I. Turesson, Majlis Book, P. Gerwins +1 more
2002Journal of Cell Biology200 citations Open access
Semantic Scholar
Activation of mitogen‐activated protein kinase cascades during priming of human neutrophils by TNF‐α and GM‐CSF
K. R. McLeish, C. Knall, Richard A. Ward, P. Gerwins +3 more
1998Journal of Leukocyte Biology156 citations
Semantic Scholar
Endoplasmic reticulum stress enhances fibrosis through IRE1α‐mediated degradation of miR‐150 and XBP‐1 splicing
F. Heindryckx, F. Binet, M. Ponticos, K. Rombouts +3 more
2016EMBO Molecular Medicine153 citations Open access
Semantic Scholar
Mast cell tumor necrosis factor α production is regulated by MEK kinases
T. Ishizuka, N. Terada, P. Gerwins, E. Hamelmann +4 more
1997152 citations Open access
Semantic Scholar
ATP and its metabolite adenosine act synergistically to mobilize intracellular calcium via the formation of inositol 1,4,5-trisphosphate in a smooth muscle cell line.
P. Gerwins, B. Fredholm
1992Journal of Biological Chemistry128 citations Open access
Semantic Scholar
Endocan is a VEGF-A and PI3K regulated gene with increased expression in human renal cancer.
E. Rennel, Sofie Mellberg, A. Dimberg, Ludvig Petersson +7 more
2007Experimental Cell Research127 citations
Semantic Scholar
Fc gamma receptor cross-linking activates p42, p38, and JNK/SAPK mitogen-activated protein kinases in murine macrophages: role for p42MAPK in Fc gamma receptor-stimulated TNF-alpha synthesis.
D. M. Rose, B. W. Winston, E. Chan, D. W. Riches +3 more
1997Journal of Immunology105 citations Open access
Semantic Scholar
Discovery of microvascular miRNAs using public gene expression data: miR-145 is expressed in pericytes and is a regulator of Fli1
E. Larsson, Peder Fredlund Fuchs, Johan Heldin, Irmeli Barkefors +10 more
2009Genome Medicine95 citations Open access
Semantic Scholar
Stimulation of adenosine A1 receptors and bradykinin receptors, which act via different G proteins, synergistically raises inositol 1,4,5-trisphosphate and intracellular free calcium in DDT1 MF-2 smooth muscle cells.
P. Gerwins, B. Fredholm
1992Proceedings of the National Academy of Sciences of the United States of America91 citations Open access
Semantic Scholar
Platelets as Key Factors in Hepatocellular Carcinoma
Nataša Pavlović, B. Rani, P. Gerwins, F. Heindryckx
2019Cancers90 citations Open access
Semantic Scholar
Targeting the tumor stroma in hepatocellular carcinoma.
F. Heindryckx, P. Gerwins
2015World Journal of Hepatology82 citations Open access
Semantic Scholar
Inactivation of Src family kinases inhibits angiogenesis in vivo: implications for a mechanism involving organization of the actin cytoskeleton.
W. Kilarski, N. Jura, P. Gerwins
2003Experimental Cell Research74 citations
Semantic Scholar
Role of the amino-terminal domains of MEKKs in the activation of NF kappa B and MAPK pathways and in the regulation of cell proliferation and apoptosis.
C. Bonvin, A. Guillon, M. V. van Bemmelen, P. Gerwins +2 more
2002Cellular Signalling64 citations
Semantic Scholar
Src family kinase‐inhibitor PP2 reduces focal ischemic brain injury
F. Lennmyr, A. Ericsson, P. Gerwins, S. Akterin +2 more
2004Acta Neurologica Scandinavica60 citations Open access
Semantic Scholar
Characterization of adenosine A1 receptors in intact DDT1 MF-2 smooth muscle cells.
P. Gerwins, C. Nordstedt, B. Fredholm
1990Molecular Pharmacology60 citations
Semantic Scholar
Glucocorticoid receptor activation leads to up-regulation of adenosine A1 receptors and down-regulation of adenosine A2 responses in DDT1 MF-2 smooth muscle cells.
P. Gerwins, B. Fredholm
1991Molecular Pharmacology58 citations
Semantic Scholar
Lactadherin binds to elastin – a starting point for medin amyloid formation?
Annika Larsson, Siwei Peng, Helena Persson, J. Rosenbloom +6 more
2006Amyloid: Journal of Protein Folding Disorders54 citations
Semantic Scholar
Role of aggregated medin in the pathogenesis of thoracic aortic aneurysm and dissection
Siwei Peng, Annika Larsson, E. Wassberg, P. Gerwins +3 more
2007Laboratory Investigation49 citations Open access
Semantic Scholar
Differential activation and regulation of mitogen‐activated protein kinases through the antigen receptor and CD40 in human B cells
N. Sakata, H. Kawasome, N. Terada, P. Gerwins +2 more
1999European Journal of Immunology39 citations Open access
Semantic Scholar
Inhibiting IRE1α-endonuclease activity decreases tumor burden in a mouse model for hepatocellular carcinoma
Nataša Pavlović, Carlemi Calitz, K. Thanapirom, G. Mazza +3 more
2020eLife36 citations Open access
Semantic Scholar
An in vivo neovascularization assay for screening regulators of angiogenesis and assessing their effects on pre-existing vessels
W. Kilarski, Ludvig Petersson, Peder Fredlund Fuchs, Marcin S. Zielinski +1 more
2012Angiogenesis36 citations Open access
Semantic Scholar
Inhibiting P2Y12 in Macrophages Induces Endoplasmic Reticulum Stress and Promotes an Anti-Tumoral Phenotype
Nataša Pavlović, M. Kopsida, P. Gerwins, F. Heindryckx
2020International Journal of Molecular Sciences34 citations Open access
Semantic Scholar
The novel alkylating prodrug melflufen (J1) inhibits angiogenesis in vitro and in vivo.
Sara Strese, M. Wickström, Peder Fredlund Fuchs, M. Fryknäs +4 more
2013Biochemical Pharmacology34 citations
Semantic Scholar
Stimulation of T-cells with OKT3 antibodies increases forskolin binding and cyclic AMP accumulation.
Anders Kvanta, P. Gerwins, Mikael Jondal, B. Fredholm
1990Cellular Signalling33 citations
Semantic Scholar
MicroRNA-24 Suppression of N-Deacetylase/N-Sulfotransferase-1 (NDST1) Reduces Endothelial Cell Responsiveness to Vascular Endothelial Growth Factor A (VEGFA)*
Z. Kasza, Peder Fredlund Fuchs, Christoffer Tamm, Anna S. Eriksson +9 more
2013Journal of Biological Chemistry30 citations Open access
Semantic Scholar
How to make tetracycline-regulated transgene expression go on and off.
E. Rennel, P. Gerwins
2002Analytical Biochemistry30 citations
Semantic Scholar
A new mechanism of blood vessel growth - hope for new treatment strategies.
W. Kilarski, P. Gerwins
2009Discover medicine29 citations
Semantic Scholar
An ex vivo model for functional studies of myofibroblasts
W. Kilarski, N. Jura, P. Gerwins
2005Laboratory Investigation28 citations Open access
Semantic Scholar
Activated platelets contribute to the progression of hepatocellular carcinoma by altering the tumor environment.
Nataša Pavlović, M. Kopsida, P. Gerwins, F. Heindryckx
2021Life Science26 citations Open access
Semantic Scholar
FGD5 sustains vascular endothelial growth factor A (VEGFA) signaling through inhibition of proteasome-mediated VEGF receptor 2 degradation.
Johan Heldin, P. O'Callaghan, Rodrigo Hernández Vera, Peder Fredlund Fuchs +2 more
2017Cellular Signalling25 citations
Semantic Scholar
Activation of adenosine A1 and bradykinin receptors increases protein kinase C and phospholipase D activity in smooth muscle cells
P. Gerwins, B. Fredholm
1995Naunyn-Schmiedeberg's Archives of Pharmacology24 citations
Semantic Scholar
Differential regulation of CD40-mediated human B cell responses by antibodies directed against different CD40 epitopes.
Naoki Sakata, E. Hamelmann, Anthony W. Siadak, Naohiro Terada +4 more
2000Cellular Immunology20 citations
Semantic Scholar
Modification of a competitive protein binding assay for determination of inositol 1,4,5-trisphosphate.
P. Gerwins
1993Analytical Biochemistry16 citations
Semantic Scholar
Fibrin fragment E potentiates TGF-β-induced myofibroblast activation and recruitment
Peder Fredlund Fuchs, Carlemi Calitz, Nataša Pavlović, F. Binet +5 more
2019bioRxiv15 citations Open access
Semantic Scholar
Regulation of endothelial cell differentiation and transformation by H-Ras.
E. Rennel, Michael J. Cross, P. Klint, Xian-He Bai +2 more
2003Experimental Cell Research12 citations
Semantic Scholar
Mechanisms of Angiogenesis: Perspectives from Antiangiogenic Tumor Therapies
Jeffrey J. Rice, P. Gerwins, W. Kilarski
20129 citations
Semantic Scholar
The imidazoline derivative calmidazolium inhibits voltage-gated Ca2+-channels and insulin release but has no effect on the phospholipase C system in insulin producing RINm5F-cells
H. Kindmark, Martin Köhler, P. Gerwins, O. Larsson +3 more
1994Bioscience Reports9 citations
Semantic Scholar
Activation of phospholipase C and phospholipase D by stimulation of adenosine A1, bradykinin or P2U receptors does not correlate well with protein kinase C activation
P. Gerwins, B. Fredholm
1995Naunyn-Schmiedeberg's Archives of Pharmacology6 citations
Semantic Scholar
Efficient Human Interferon-α Gene Transfer to Neuroendocrine Tumor Cells with Long-Term and Stable Expression
Ming-Hui Liu, W. Kilarski, P. Gerwins, K. Öberg +1 more
2006Neuroendocrinology5 citations
Semantic Scholar
Signalling via G-protein coupled receptors--using adenosine receptors as an example.
B. Fredholm, P. Gerwins, Björn Johansson, Fiona E. Parkinson +1 more
1993Drug Design and Discovery4 citations
Semantic Scholar
Stimulation of adenosine Al receptors and bradykinin receptors, which act via different G proteins, synergistically raises inositol 1,4,5-trisphosphate and intracellular free calcium in DDT1 MF-2 smooth muscle cells
P. Gerwins, B. Fredholm
4 citations
Semantic Scholar
Massive Chylous Ascites in a 9-Year-Old Girl with Malrotation—A Case Report
Hans Winberg, P. Gerwins, Kristine Hagelsteen
2023European Journal of Pediatric Surgery Reports2 citations Open access
Semantic Scholar
Medin and medin-amyloid in thoracic aortic aneurysm and dissection
Siwei Peng, E. Wassberg, P. Gerwins, S. Thelin +1 more
20062 citations
Semantic Scholar

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