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R. Fiume · SciRah

Researcher profile · Semantic Scholar

R. Fiume

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R. Fiume — researcher profile on SciRah

h-index: 30
Works: 75
Citations: 1,783

Most-cited papers

Requirement of Inositol Pyrophosphates for Full Exocytotic Capacity in Pancreatic β Cells
C. Illies, J. Gromada, R. Fiume, B. Leibiger +8 more
2007Science178 citations
Semantic Scholar
Up‐regulation of nuclear PLCβ1 in myogenic differentiation
I. Faenza, A. Bavelloni, R. Fiume, G. Lattanzi +6 more
200371 citations
Semantic Scholar
Nuclear phospholipase C: involvement in signal transduction.
L. Manzoli, A. Martelli, A. Billi, I. Faenza +2 more
2005Progress in lipid research64 citations
Semantic Scholar
Inositide-dependent phospholipase C signaling mimics insulin in skeletal muscle differentiation by affecting specific regions of the cyclin D3 promoter.
I. Faenza, G. Ramazzotti, A. Bavelloni, R. Fiume +6 more
2007Endocrinology63 citations
Semantic Scholar
PIP4K and the role of nuclear phosphoinositides in tumour suppression.
R. Fiume, Yvette Stijf-Bultsma, Z. Shah, W. Keune +3 more
2015Biochimica et Biophysica Acta59 citations
Semantic Scholar
Nuclear Phosphoinositides: Their Regulation and Roles in Nuclear Functions
R. Fiume, I. Faenza, B. Sheth, Alessandro Poli +12 more
2019International Journal of Molecular Sciences58 citations Open access
Semantic Scholar
Involvement of nuclear PLCβl in lamin B1 phosphorylation and G2/M cell cycle progression
R. Fiume, G. Ramazzotti, G. Teti, F. Chiarini +4 more
2009The FASEB Journal55 citations Open access
Semantic Scholar
Phosphoinositide-specific phospholipase C (PI-PLC) beta1 and nuclear lipid-dependent signaling.
L. Cocco, I. Faenza, R. Fiume, Anna Maria Billi +2 more
2006Biochimica et Biophysica Acta51 citations
Semantic Scholar
Catalytic activity of nuclear PLC-beta(1) is required for its signalling function during C2C12 differentiation.
G. Ramazzotti, I. Faenza, G. Gaboardi, M. Piazzi +5 more
2008Cellular Signalling48 citations
Semantic Scholar
Expression of phospholipase C beta family isoenzymes in C2C12 myoblasts during terminal differentiation
I. Faenza, A. Bavelloni, R. Fiume, P. Santi +5 more
2004Journal of Cellular Physiology48 citations Open access
Semantic Scholar
Nuclear phosphoinositide specific phospholipase C (PI-PLC)-beta 1: a central intermediary in nuclear lipid-dependent signal transduction.
A. Martelli, R. Fiume, I. Faenza, G. Tabellini +5 more
2005Histology and Histopathology46 citations
Semantic Scholar
Nuclear diacylglycerol kinase‐ζ is a negative regulator of cell cycle progression in C2C12 mouse myoblasts
C. Evangelisti, P. Tazzari, M. Riccio, R. Fiume +6 more
2007The FASEB Journal44 citations Open access
Semantic Scholar
BMP-2 induced expression of PLC beta1 that is a positive regulator of osteoblast differentiation
G. Ramazzotti, R. Fiume, Cristina Mazzetti, A. Matteucci +2 more
2015Italian Journal of Anatomy and Embryology40 citations Open access
Semantic Scholar
Real-time PCR as a tool for quantitative analysis of PI-PLCbeta1 gene expression in myelodysplastic syndrome.
M. Follo, C. Bosi, C. Finelli, R. Fiume +5 more
2006International Journal of Molecular Medicine40 citations Open access
Semantic Scholar
PLC-β1 and cell differentiation: An insight into myogenesis and osteogenesis.
G. Ramazzotti, I. Faenza, R. Fiume, A. Billi +7 more
2017Advances in Biological Regulation39 citations Open access
Semantic Scholar
Nuclear inositide specific phospholipase C signalling – interactions and activity
I. Faenza, R. Fiume, M. Piazzi, A. Colantoni +1 more
2013The FEBS Journal39 citations Open access
Semantic Scholar
Phosphoinositide 3 Kinase Signaling in Human Stem Cells from Reprogramming to Differentiation: A Tale in Cytoplasmic and Nuclear Compartments
G. Ramazzotti, Stefano Ratti, R. Fiume, M. Follo +6 more
2019International Journal of Molecular Sciences38 citations Open access
Semantic Scholar
Nuclear phosphoinositides: location, regulation and function.
R. Fiume, W. Keune, I. Faenza, Yvette Bultsma +7 more
2012Sub-cellular biochemistry38 citations
Semantic Scholar
Nuclear inositol lipid metabolism: More than just second messenger generation?
A. Martelli, M. Follo, C. Evangelisti, F. Falà +3 more
2005Journal of Cellular Biochemistry38 citations
Semantic Scholar
Nuclear phospholipase C signaling through type 1 IGF receptor and its involvement in cell growth and differentiation.
I. Faenza, A. Billi, M. Follo, R. Fiume +3 more
2005Anticancer Research38 citations
Semantic Scholar
Nuclear phospholipase C β1 signaling, epigenetics and treatments in MDS.
M. Follo, S. Marmiroli, I. Faenza, R. Fiume +7 more
2013Advances in Biological Regulation37 citations Open access
Semantic Scholar
The physiology and pathology of inositide signaling in the nucleus
G. Ramazzotti, I. Faenza, R. Fiume, A. Matteucci +3 more
2011Journal of Cellular Physiology37 citations
Semantic Scholar
Phosphatidylinositol 5 Phosphate (PI5P): From Behind the Scenes to the Front (Nuclear) Stage
A. Poli, A. Zaurito, Shidqiyyah Abdul-Hamid, R. Fiume +2 more
2019International Journal of Molecular Sciences36 citations Open access
Semantic Scholar
Nuclear Phospholipase C β1 (PLCβ1) Affects CD24 Expression in Murine Erythroleukemia Cells*
R. Fiume, I. Faenza, A. Matteucci, A. Astolfi +3 more
2005Journal of Biological Chemistry36 citations Open access
Semantic Scholar
PIP4Ks impact on PI3K, FOXP3, and UHRF1 signaling and modulate human regulatory T cell proliferation and immunosuppressive activity
A. Poli, Shidqiyyah Abdul-Hamid, A. Zaurito, F. Campagnoli +6 more
2021Proceedings of the National Academy of Sciences of the United States of America35 citations Open access
Semantic Scholar
Nuclear inositide signaling and cell cycle.
Stefano Ratti, G. Ramazzotti, I. Faenza, R. Fiume +7 more
2017Advances in Biological Regulation35 citations Open access
Semantic Scholar
Nuclear inositide signaling in myelodysplastic syndromes
M. Follo, S. Mongiorgi, C. Finelli, C. Clissa +6 more
2010Journal of Cellular Biochemistry34 citations
Semantic Scholar
Nuclear Localization of Diacylglycerol Kinase Alpha in K562 Cells Is Involved in Cell Cycle Progression
A. Poli, R. Fiume, G. Baldanzi, D. Capello +7 more
2017Journal of Cellular Physiology32 citations Open access
Semantic Scholar
Nuclear phospholipase C isoenzyme imbalance leads to pathologies in brain, hematologic, neuromuscular, and fertility disorders[S]
Stefano Ratti, M. Follo, G. Ramazzotti, I. Faenza +5 more
2018Journal of Lipid Research31 citations Open access
Semantic Scholar
Up-regulation of nuclear PLCbeta1 in myogenic differentiation.
I. Faenza, A. Bavelloni, R. Fiume, G. Lattanzi +6 more
2003Journal of Cellular Physiology30 citations
Semantic Scholar
Phospholipase C-β1 interacts with cyclin E in adipose- derived stem cells osteogenic differentiation.
G. Ramazzotti, R. Fiume, F. Chiarini, G. Campana +8 more
2019Advances in Biological Regulation29 citations Open access
Semantic Scholar
Nuclear PLCs affect insulin secretion by targeting PPARγ in pancreatic β cells
R. Fiume, G. Ramazzotti, I. Faenza, M. Piazzi +3 more
2012The FASEB Journal29 citations
Semantic Scholar
A role for PLCβ1 in myotonic dystrophies type 1 and 2
I. Faenza, W. Blalock, A. Bavelloni, B. Schoser +5 more
2012The FASEB Journal28 citations
Semantic Scholar
eEF1A Phosphorylation in the Nucleus of Insulin-stimulated C2C12 Myoblasts
M. Piazzi, A. Bavelloni, I. Faenza, W. Blalock +6 more
2010Molecular & Cellular Proteomics26 citations Open access
Semantic Scholar
Revisiting nuclear phospholipase C signalling in MDS.
M. Follo, I. Faenza, R. Fiume, G. Ramazzotti +4 more
2012Advances in Biological Regulation25 citations
Semantic Scholar
Nuclear Phosphoinositides as Key Determinants of Nuclear Functions
M. C. Vidalle, Bhavwanti Sheth, Antonietta Fazio, Maria Vittoria Marvi +11 more
2023Biomolecules24 citations Open access
Semantic Scholar
PLC-beta 1 regulates the expression of miR-210 during mithramycin-mediated erythroid differentiation in K562 cells
A. Bavelloni, A. Poli, R. Fiume, W. Blalock +5 more
2014OncoTarget21 citations Open access
Semantic Scholar
Physiology and pathology of nuclear phospholipase C β1.
L. Cocco, M. Follo, I. Faenza, R. Fiume +4 more
2011Advances in Enzyme Regulation16 citations
Semantic Scholar
A role for PKCepsilon during C2C12 myogenic differentiation.
G. Gaboardi, G. Ramazzotti, A. Bavelloni, M. Piazzi +5 more
2010Cellular Signalling16 citations
Semantic Scholar
Signal transduction within the nucleus: revisiting phosphoinositide inositide-specific phospholipase Cbeta1.
L. Cocco, A. Martelli, R. Fiume, I. Faenza +2 more
2006Advances in Enzyme Regulation16 citations
Semantic Scholar
Nuclear phospholipase C in biological control and cancer.
G. Ramazzotti, I. Faenza, M. Follo, R. Fiume +4 more
2011Critical Reviews in Eukaryotic Gene Expression14 citations
Semantic Scholar
Nuclear phospholipase C beta1 (PLCbeta1) affects CD24 expression in murine erythroleukemia cells.
R. Fiume, I. Faenza, A. Matteucci, A. Astolfi +3 more
2005Journal of Biological Chemistry14 citations
Semantic Scholar
Diphosphoinositol pentakisphosphate as a novel mediator of insulin exocytosis.
C. J. Barker, C. Illies, R. Fiume, G. Gaboardi +2 more
2009Advances in Enzyme Regulation10 citations
Semantic Scholar
Roles of PI3K/AKT/mTOR Axis in Arteriovenous Fistula
Stefano Ratti, R. Mauro, C. Rocchi, S. Mongiorgi +5 more
2022Biomolecules9 citations Open access
Semantic Scholar
Recent advances in MDS mutation landscape: Splicing and signalling.
M. Follo, A. Pellagatti, Stefano Ratti, G. Ramazzotti +8 more
2019Advances in Biological Regulation9 citations Open access
Semantic Scholar
Nuclear PI-PLC β1 and Myelodysplastic syndromes: from bench to clinics.
S. Mongiorgi, M. Follo, C. Clissa, R. Giardino +6 more
2012Current Topics in Microbiology and Immunology9 citations
Semantic Scholar
Emerging Roles of Phospholipase C Beta Isozymes as Potential Biomarkers in Cardiac Disorders
Antonietta Fazio, C. Evangelisti, A. Cappellini, S. Mongiorgi +8 more
2023International Journal of Molecular Sciences8 citations Open access
Semantic Scholar
Deciphering signaling pathways in hematopoietic stem cells: the molecular complexity of Myelodysplastic Syndromes (MDS) and leukemic progression.
Irene Casalin, Alessia de Stefano, Eleonora Ceneri, A. Cappellini +14 more
2024Advances in Biological Regulation6 citations Open access
Semantic Scholar
“Modulating Phosphoinositide Profiles as a Roadmap for Treatment in Acute Myeloid Leukemia”
Stefano Ratti, C. Evangelisti, S. Mongiorgi, Alessia de Stefano +11 more
2021Frontiers in Oncology6 citations Open access
Semantic Scholar
Exploring the controversial role of PI3K signalling in CD4+ regulatory T (T-Reg) cells.
A. Poli, R. Fiume, S. Mongiorgi, A. Zaurito +10 more
2020Advances in Biological Regulation5 citations
Semantic Scholar

Frequent co-authors

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I. Faenza×38
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I. Faenza — researcher profile on SciRah
L. Cocco×37
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L. Cocco — researcher profile on SciRah
G. Ramazzotti×26
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G. Ramazzotti — researcher profile on SciRah
M. Follo×23
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M. Follo — researcher profile on SciRah

×20

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L. Manzoli — researcher profile on SciRah

A. Martelli×15

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A. Martelli — researcher profile on SciRah

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A. Billi — researcher profile on SciRah

Stefano Ratti×13

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Stefano Ratti — researcher profile on SciRah

A. Bavelloni×10

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A. Bavelloni — researcher profile on SciRah

S. Mongiorgi×10

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S. Mongiorgi — researcher profile on SciRah

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N. Divecha — researcher profile on SciRah

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M. Piazzi — researcher profile on SciRah