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H. Jabara · SciRah

Researcher profile · Semantic Scholar

H. Jabara

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H. Jabara — researcher profile on SciRah

h-index: 38
Works: 78
Citations: 6,475

Most-cited papers

TACI and BAFF-R mediate isotype switching in B cells
E. Castigli, S. Wilson, Sumi Scott, F. Dedeoğlu +5 more
2005Journal of Experimental Medicine599 citations Open access
Semantic Scholar
The regulation of immunoglobulin E class-switch recombination
R. Geha, H. Jabara, S. Brodeur
2003Nature reviews. Immunology484 citations
Semantic Scholar
Impaired IgA class switching in APRIL-deficient mice.
E. Castigli, Sumi Scott, F. Dedeoğlu, P. Bryce +4 more
2004Proceedings of the National Academy of Sciences of the United States of America474 citations Open access
Semantic Scholar
CD40 and IgE: synergism between anti-CD40 monoclonal antibody and interleukin 4 in the induction of IgE synthesis by highly purified human B cells
H. Jabara, Shu-Man Fu, R. Geha, D. Vercelli
1990Journal of Experimental Medicine447 citations Open access
Semantic Scholar
Defective expression of the CD40 ligand in X chromosome-linked immunoglobulin deficiency with normal or elevated IgM.
R. Fuleihan, N. Ramesh, R. Loh, H. Jabara +5 more
1993Proceedings of the National Academy of Sciences of the United States of America371 citations Open access
Semantic Scholar
Induction of human IgE synthesis requires interleukin 4 and T/B cell interactions involving the T cell receptor/CD3 complex and MHC class II antigens
Donata Vercelli, H. Jabara, K. Arai, R. Geha
1989Journal of Experimental Medicine338 citations Open access
Semantic Scholar
Human recombinant interleukin 4 induces Fc epsilon R2/CD23 on normal human monocytes
Donata Vercelli, H. Jabara, Bee-Wah Lee, Nancy Woodland +2 more
1988Journal of Experimental Medicine260 citations Open access
Semantic Scholar
A missense mutation in TFRC, encoding transferrin receptor 1, causes combined immunodeficiency
H. Jabara, Steven E. Boyden, J. Chou, N. Ramesh +24 more
2015Nature Genetics255 citations Open access
Semantic Scholar
IL-4 inhibits the synthesis of IFN-gamma and induces the synthesis of IgE in human mixed lymphocyte cultures.
Donata Vercelli, H. Jabara, R. Lauener, R. Geha
1990Journal of Immunology253 citations Open access
Semantic Scholar
Endogenous interleukin 6 plays an obligatory role in interleukin 4‐dependent human IgE synthesis
D. Vercelli, H. Jabara, K. Arai, T. Yokota +1 more
1989European Journal of Immunology215 citations
Semantic Scholar
Molecular analysis of the induction of immunoglobulin E synthesis in human B cells by interleukin 4 and engagement of CD40 antigen
S. K. Shapira, Donata Vercelli, H. Jabara, Shu-Man Fu +1 more
1992Journal of Experimental Medicine149 citations Open access
Semantic Scholar
Hydrocortisone and IL-4 induce IgE isotype switching in human B cells.
H. Jabara, Deborah Ahern, Donata Vercelli, R. Geha
1991Journal of Immunology148 citations Open access
Semantic Scholar
DOCK8 functions as an adaptor that links Toll-like receptor–MyD88 signaling to B cell activation
H. Jabara, Douglas R. McDonald, E. Janssen, M. Massaad +27 more
2012Nature Immunology145 citations Open access
Semantic Scholar
The binding site for TRAF2 and TRAF3 but not for TRAF6 is essential for CD40-mediated immunoglobulin class switching.
H. Jabara, D. Laouini, E. Tsitsikov, E. Mizoguchi +6 more
2002Immunity145 citations Open access
Semantic Scholar
A Homozygous mucosa-associated ly 1 mphoid tissue 1 (MALT1) mutation in a family with 2 combined immunodeficiency
H. Jabara, T. Ohsumi, J. Chou, M. Massaad +15 more
2013Journal of Allergy and Clinical Immunology139 citations Open access
Semantic Scholar
gamma/delta T lymphocytes express CD40 ligand and induce isotype switching in B lymphocytes
Anthony Horner, H. Jabara, N. Ramesh, R. Geha
1995Journal of Experimental Medicine123 citations Open access
Semantic Scholar
Functional heterogeneity among human inducer T cell clones.
Dale T. Umetsu, H. Jabara, R. DeKruyff, A. Abbas +2 more
1988Journal of Immunology123 citations Open access
Semantic Scholar
Sequential switching from mu to epsilon via gamma 4 in human B cells stimulated with IL-4 and hydrocortisone.
H. Jabara, R. Loh, N. Ramesh, Donata Vercelli +1 more
1993Journal of Immunology105 citations
Semantic Scholar
DOCK8 Functions as an Adaptor that Links TLR–MyD88 Signaling to B Cell Activation
H. Jabara, Douglas R. McDonald, E. Janssen, M. Massaad +31 more
2012101 citations
Semantic Scholar
Antigen presentation by human dermal fibroblasts: activation of resting T lymphocytes.
D. Umetsu, D. Katzen, H. Jabara, R. Geha
1986Journal of Immunology85 citations
Semantic Scholar
Molecular Mechanisms of Immunoglobulin E Regulation
Leonard B. Bacharier, H. Jabara, R. Geha
1998International Archives of Allergy and Immunology84 citations
Semantic Scholar
Glucocorticoids upregulate CD40 ligand expression and induce CD40L-dependent immunoglobulin isotype switching.
H. Jabara, S. Brodeur, R. Geha
2001Journal of Clinical Investigation78 citations Open access
Semantic Scholar
Deficiency of base excision repair enzyme NEIL3 drives increased predisposition to autoimmunity.
M. Massaad, Jia Zhou, D. Tsuchimoto, J. Chou +24 more
2016Journal of Clinical Investigation75 citations Open access
Semantic Scholar
Deletional switch recombination occurs in interleukin-4-induced isotype switching to IgE expression by human B cells.
S. K. Shapira, H. Jabara, C. P. Thienes, Deborah Ahern +3 more
1991Proceedings of the National Academy of Sciences of the United States of America73 citations Open access
Semantic Scholar
Induction of germ-line and mature C epsilon transcripts in human B cells stimulated with rIL-4 and EBV.
H. Jabara, Lynda C. Schneider, S. K. Shapira, C. Alfieri +4 more
1990Journal of Immunology73 citations
Semantic Scholar
Regulation of immunoglobulin (Ig)E synthesis in the hyper-IgE syndrome.
Donata Vercelli, H. Jabara, Charlotte Cunningham-Rundles, J. Abrams +5 more
1990Journal of Clinical Investigation72 citations Open access
Semantic Scholar
Differential requirements of B cells from normal and allergic subjects for the induction of IgE synthesis by an alloreactive T cell clone
D. Umetsu, Donald Y. M. Leung, R. Siraganian, H. Jabara +1 more
1985Journal of Experimental Medicine60 citations Open access
Semantic Scholar
The murine equivalent of the A181E TACI mutation associated with common variable immunodeficiency severely impairs B-cell function.
J. Lee, I. Rauter, L. Garibyan, Esra Ozcan +7 more
2009Blood56 citations Open access
Semantic Scholar
Allogeneic transplantation successfully corrects immune defects, but not susceptibility to colitis, in a patient with nuclear factor-кB essential modulator deficiency
S. Pai, O. Levy, H. Jabara, J. Glickman +5 more
2008Journal of Allergy and Clinical Immunology56 citations Open access
Semantic Scholar
Flow cytometry diagnosis of dedicator of cytokinesis 8 (DOCK8) deficiency
S. Pai, H. D. de Boer, M. Massaad, T. Chatila +9 more
2014Journal of Allergy and Clinical Immunology55 citations Open access
Semantic Scholar
Human dermal fibroblasts present tetanus toxoid antigen to antigen-specific T cell clones.
D. Umetsu, J. Pober, H. Jabara, W. Fiers +4 more
1985Journal of Clinical Investigation55 citations Open access
Semantic Scholar
IL-3 Induces B7.2 (CD86) Expression and Costimulatory Activity in Human Eosinophils
J. Celestin, Olaf Rotschke, K. Falk, N. Ramesh +3 more
2001Journal of Immunology53 citations
Semantic Scholar
The superantigen toxic shock syndrome toxin-1 induces CD40 ligand expression and modulates IgE isotype switching.
H. Jabara, R. Geha
1996International Immunology53 citations Open access
Semantic Scholar
The C104R mutant impairs the function of transmembrane activator and calcium modulator and cyclophilin ligand interactor (TACI) through haploinsufficiency
J. Lee, H. Jabara, L. Garibyan, I. Rauter +4 more
2010Journal of Allergy and Clinical Immunology52 citations Open access
Semantic Scholar
Disodium cromoglycate inhibits S mu-->S epsilon deletional switch recombination and IgE synthesis in human B cells
R. Loh, H. Jabara, R. Geha
1994Journal of Experimental Medicine52 citations Open access
Semantic Scholar
Plasmacytoid Dendritic Cell Depletion in DOCK8 Deficiency: Rescue of Severe Herpetic Infections with Interferon Alpha-2b Therapy
S. Keleş, H. Jabara, I. Reisli, Douglas R. McDonald +7 more
2014Journal of Allergy and Clinical Immunology50 citations Open access
Semantic Scholar
Analysis of in vitro lymphocyte proliferation as a screening tool for cellular immunodeficiency.
K. Stone, H. Feldman, C. Huisman, C. Howlett +2 more
2009Clinical Immunology50 citations
Semantic Scholar
Jun N-terminal kinase is essential for CD40-mediated IgE class switching in B cells.
H. Jabara, R. Geha
2005Journal of Allergy and Clinical Immunology41 citations Open access
Semantic Scholar
Successful Interferon–alpha 2b Therapy for Unremitting Warts in a Patient with DOCK8 Deficiency
D. al-Zahrani, A. Raddadi, M. Massaad, S. Keleş +3 more
2014Clinical Immunology37 citations Open access
Semantic Scholar
Role of JAK3 in CD40-mediated signaling.
H. Jabara, Rebecca H. Buckley, Joseph L. Roberts, G. Lefranc +3 more
1998Blood37 citations
Semantic Scholar
Defective lymphoid organogenesis underlies the immune deficiency caused by a heterozygous S32I mutation in IκBα
J. Mooster, S. Le Bras, M. Massaad, H. Jabara +7 more
2015Journal of Experimental Medicine35 citations Open access
Semantic Scholar
Functional analysis of TACI mutations associated with CVID
A. Fried, I. Rauter, S. Dillon, H. Jabara +1 more
2011Journal of Allergy and Clinical Immunology34 citations Open access
Semantic Scholar
Engagement of CD14 on monocytes inhibits the synthesis of human Igs, including IgE.
H. Jabara, Donata Vercelli
1994Journal of Immunology34 citations Open access
Semantic Scholar
Requirements for activation of human peripheral blood T cells by mouse monoclonal antibodies to CD3.
D. Umetsu, David Katzen, T. Chatila, Richard A. Miller +5 more
1987Clinical Immunology and Immunopathology32 citations
Semantic Scholar
B-cell receptor cross-linking delays activation-induced cytidine deaminase induction and inhibits class-switch recombination to IgE.
H. Jabara, J. Chaudhuri, S. Dutt, F. Dedeoğlu +6 more
2008Journal of Allergy and Clinical Immunology29 citations
Semantic Scholar
TRAF2 and TRAF3 independently mediate Ig class switching driven by CD40.
H. Jabara, Yu Weng, Tatyana Sannikova, R. Geha
2009International Immunology24 citations Open access
Semantic Scholar
Role of protein tyrosine kinases and phosphatases in isotype switching: crosslinking CD45 to CD40 inhibits IgE isotype switching in human B cells.
R. Loh, H. Jabara, Clement L. Ren, Shu-Man Fu +2 more
1995Immunology Letters19 citations
Semantic Scholar
Role of protein tyrosine kinases in CD40/interleukin-4-mediated isotype switching to IgE.
R. Loh, H. Jabara, Clement L. Ren, Shu-Man Fu +1 more
1994Journal of Allergy and Clinical Immunology18 citations Open access
Semantic Scholar
TRIF signaling is essential for TLR4-driven IgE class switching
E. Janssen, Esra Ozcan, Kyriaki Liadaki, H. Jabara +6 more
2014Journal of Immunology17 citations Open access
Semantic Scholar
Mechanisms of inhibition of IgE synthesis by nedocromil sodium: nedocromil sodium inhibits deletional switch recombination in human B cells.
R. Loh, H. Jabara, R. Geha
1996Journal of Allergy and Clinical Immunology17 citations
Semantic Scholar

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M. Massaad×8
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N. Ramesh×7
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Shu-Man Fu — researcher profile on SciRah

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I. Rauter — researcher profile on SciRah

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G. Lefranc — researcher profile on SciRah

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S. Keleş — researcher profile on SciRah