Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

Christoph Kuppe · SciRah

Researcher profile · Semantic Scholar

Christoph Kuppe

Share profile

Christoph Kuppe — researcher profile on SciRah

h-index: 29
Works: 86
Citations: 4,502

Most-cited papers

Decoding myofibroblast origins in human kidney fibrosis
Christoph Kuppe, Mahmoud M. Ibrahim, J. Kranz, Xiaoting Zhang +25 more
2020Nature676 citations Open access
Semantic Scholar
Spatial multi-omic map of human myocardial infarction
Christoph Kuppe, R. Ramirez Flores, Zhijian Li, M. Hannani +15 more
2020bioRxiv556 citations Open access
Semantic Scholar
A small-molecule TNIK inhibitor targets fibrosis in preclinical and clinical models
F. Ren, A. Aliper, Jian Chen, Heng Zhao +26 more
2024Nature Biotechnology308 citations Open access
Semantic Scholar
Adventitial MSC-like cells are progenitors of vascular smooth muscle cells and drive vascular calcification in chronic kidney disease
R. Kramann, C. Goettsch, J. Wongboonsin, H. Iwata +11 more
2016Cell Stem Cell308 citations Open access
Semantic Scholar
Platelet-instructed SPP1+ macrophages drive myofibroblast activation in fibrosis in a CXCL4-dependent manner
K. Hoeft, Gideon J. L. Schaefer, Hyojin Kim, David Schumacher +18 more
2023Cell Reports289 citations Open access
Semantic Scholar
Targeting immune–fibroblast cell communication in heart failure
Junedh M. Amrute, Xin Luo, Vinay R. Penna, Steven Yang +32 more
2024Nature266 citations Open access
Semantic Scholar
SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids
J. Jansen, Katharina C. Reimer, J. Nagai, Finny S. Varghese +43 more
2021Cell Stem Cell218 citations Open access
Semantic Scholar
Heterogeneous bone-marrow stromal progenitors drive myelofibrosis via a druggable alarmin axis
N. Leimkühler, Hélène F. E. Gleitz, Ronghui Li, I. Snoeren +21 more
2020Cell Stem Cell160 citations Open access
Semantic Scholar
Spatial multi-omic map of human myocardial infarction
Christoph Kuppe, R. Ramirez Flores, Zhijian Li, S. Hayat +38 more
2022Nature150 citations Open access
Semantic Scholar
Causal integration of multi‐omics data with prior knowledge to generate mechanistic hypotheses
Aurélien J. F. Dugourd, Christoph Kuppe, M. Sciacovelli, Enio Gjerga +14 more
2020bioRxiv133 citations Open access
Semantic Scholar
Chromatin-accessibility estimation from single-cell ATAC-seq data with scOpen
Zhijian Li, Christoph Kuppe, S. Ziegler, Mingbo Cheng +5 more
2021Nature Communications111 citations Open access
Semantic Scholar
Only Hyperuricemia with Crystalluria, but not Asymptomatic Hyperuricemia, Drives Progression of Chronic Kidney Disease.
M. Sellmayr, M. H. Hernández Petzsche, Qiuyue Ma, Nils Krüger +15 more
2020Journal of the American Society of Nephrology107 citations Open access
Semantic Scholar
NECTIN4 Amplification Is Frequent in Solid Tumors and Predicts Enfortumab Vedotin Response in Metastatic Urothelial Cancer
N. Klümper, Ngoc Khanh Tran, S. Zschäbitz, Oliver Hahn +37 more
2024Journal of Clinical Oncology100 citations Open access
Semantic Scholar
Spatial multi-omics: novel tools to study the complexity of cardiovascular diseases
Paul Kiessling, Christoph Kuppe
2024Genome Medicine96 citations Open access
Semantic Scholar
mTOR-mediated podocyte hypertrophy regulates glomerular integrity in mice and humans.
Victor G. Puelles, J. W. van der Wolde, N. Wanner, M. Scheppach +29 more
2019JCI Insight95 citations Open access
Semantic Scholar
Mapping the cardiac vascular niche in heart failure
F. Peisker, Maurice Halder, J. Nagai, S. Ziegler +12 more
2022Nature Communications91 citations Open access
Semantic Scholar
Defining cardiac functional recovery in end-stage heart failure at single-cell resolution
Junedh M. Amrute, Lu-Lu Lai, Pan Ma, Andrew L. Koenig +16 more
2023Nature Cardiovascular Research67 citations Open access
Semantic Scholar
Adult human kidney organoids originate from CD24+ cells and represent an advanced model for adult polycystic kidney disease
Yao-Xian Xu, Christoph Kuppe, J. Perales-Patón, S. Hayat +35 more
2022Nature Genetics60 citations Open access
Semantic Scholar
Human pluripotent stem cell-derived kidney organoids for personalized congenital and idiopathic nephrotic syndrome modeling
J. Jansen, Bartholomeus T. van den Berge, M. van den Broek, R. Maas +28 more
2021bioRxiv51 citations Open access
Semantic Scholar
Heterogeneity and plasticity in healthy and atherosclerotic vasculature explored by single-cell sequencing
K. van Kuijk, Christoph Kuppe, C. Betsholtz, M. Vanlandewijck +2 more
2019Cardiovascular Research46 citations Open access
Semantic Scholar
Deep learning–based molecular morphometrics for kidney biopsies
Marina Zimmermann, Martin Klaus, M. N. Wong, Ann-Katrin Thebille +15 more
2020bioRxiv40 citations Open access
Semantic Scholar
scMEGA: single-cell multi-omic enhancer-based gene regulatory network inference
Zhijian Li, J. Nagai, Christoph Kuppe, R. Kramann +1 more
2022bioRxiv39 citations Open access
Semantic Scholar
Dynamic partitioning of branched-chain amino acids-derived nitrogen supports renal cancer progression
M. Sciacovelli, Aurélien J. F. Dugourd, L. V. Jimenez, Ming Yang +24 more
2022Nature Communications38 citations Open access
Semantic Scholar
Human and murine fibroblast single-cell transcriptomics reveals fibroblast clusters are differentially affected by ageing and serum cholesterol
K. van Kuijk, I. McCracken, Renée J. H. A. Tillie, S. Asselberghs +24 more
2023Cardiovascular Research37 citations Open access
Semantic Scholar
Novel 3D analysis using optical tissue clearing documents the evolution of murine rapidly progressive glomerulonephritis.
Victor G. Puelles, David Fleck, Lena Ortz, Stella Papadouri +25 more
2019Kidney International36 citations Open access
Semantic Scholar
Detection of PatIent-Level distances from single cell genomics and pathomics data with Optimal Transport (PILOT)
Mehdi Joodaki, Mina Shaigan, V. Parra, R. D. Bülow +13 more
2023bioRxiv34 citations Open access
Semantic Scholar
Role of mesenchymal stem cells in kidney injury and fibrosis
Christoph Kuppe, R. Kramann
2016Current opinion in nephrology and hypertension33 citations
Semantic Scholar
Expansion-enhanced super-resolution radial fluctuations enable nanoscale molecular profiling of pathology specimens
Dominik Kylies, Marina Zimmermann, Fabian Haas, M. Schwerk +33 more
2023Nature Nanotechnology32 citations Open access
Semantic Scholar
Pathology-oriented multiplexing enables integrative disease mapping
Malte Kuehl, Y. Okabayashi, Milagros N. Wong, Lukas Gernhold +71 more
2025Nature31 citations Open access
Semantic Scholar
Targeting Immune-Fibroblast Crosstalk in Myocardial Infarction and Cardiac Fibrosis
Junedh M. Amrute, Xin Luo, Vinay Penna, Andrea L. Bredemeyer +22 more
2023Research Square29 citations Open access
Semantic Scholar
Targeting modulated vascular smooth muscle cells in atherosclerosis via FAP-directed immunotherapy
Junedh M. Amrute, In-Hyuk Jung, Tracy Yamawaki, Wen-Ling Lin +35 more
2026Science24 citations Open access
Semantic Scholar
Vascular Niches Are the Primary Hotspots in Cardiac Aging
David Rodriguez Morales, Veronica Larcher, Mariano Ruz Jurado, Denada Arifaj +8 more
2025Circulation Research24 citations Open access
Semantic Scholar
Deficiency of myeloid PHD proteins aggravates atherogenesis via macrophage apoptosis and paracrine fibrotic signaling
K. van Kuijk, J. Demandt, Javier Perales-Patón, Thomas L. Theelen +13 more
2021Atherosclerosis24 citations
Semantic Scholar
Disruption of CUL3-mediated ubiquitination causes proximal tubule injury and kidney fibrosis
Turgay Saritas, Catherina A. Cuevas, Mohammed Z. Ferdaus, Christoph Kuppe +5 more
2019Scientific Reports23 citations Open access
Semantic Scholar
A Functional Landscape of CKD Entities From Public Transcriptomic Data
F. Tajti, Christoph Kuppe, A. Antoranz, Mahmoud M. Ibrahim +8 more
2019Kidney International Reports19 citations Open access
Semantic Scholar
Cell–cell crosstalk in kidney health and disease
Emilia Scheidereit, Lampros Mavrommatis, Christoph Kuppe
2025Nature Reviews Nephrology17 citations
Semantic Scholar
Dissecting CD8+ T cell pathology of severe SARS-CoV-2 infection by single-cell immunoprofiling
Felix Schreibing, M. Hannani, Hyojin Kim, J. Nagai +25 more
2022Frontiers in Immunology17 citations Open access
Semantic Scholar
Generation of a conditional cellular senescence model using proximal tubule cells and fibroblasts from human kidneys
Xiaohang Shao, Hua-Ming Xu, Hyojin Kim, Sadaf Ljaz +13 more
2024Cell Death Discovery12 citations Open access
Semantic Scholar
Advancing Cardiovascular Research With Single-Cell and Spatial Transcriptomics.
Kai Li, Samaneh Samiei, Daryna Pikulska, Sebastian Foecking +1 more
2026Circulation Research11 citations
Semantic Scholar
Targeting the Immune-Fibrosis Axis in Myocardial Infarction and Heart Failure
Junedh M. Amrute, Xin Luo, Vinay Penna, Andrea L. Bredemeyer +22 more
2022bioRxiv11 citations Open access
Semantic Scholar
Immunoregulatory Endothelial Cells Interact With T Cells After Myocardial Infarction
L. Tombor, T. Lautenschläger, S. Glaser, A. Fischer +31 more
2025Circulation Research10 citations Open access
Semantic Scholar
PHLOWER leverages single-cell multimodal data to infer complex, multi-branching cell differentiation trajectories
Ming-Bo Cheng, Jitske Jansen, Katharina C. Reimer, Vincent P. Grande +8 more
2025Nature Methods10 citations Open access
Semantic Scholar
Experimental and computational technologies to dissect the kidney at the single-cell level.
Christoph Kuppe, J. Perales-Patón, J. Saez-Rodriguez, R. Kramann
2020Nephrology, Dialysis and Transplantation10 citations Open access
Semantic Scholar
Deficiency of myeloid PHD proteins aggravates atherogenesis via macrophage apoptosis and paracrine fibrotic signalling
K. van Kuijk, J. Demandt, J. Perales-Patón, T. Theelen +16 more
2021Cardiovascular Research9 citations Open access
Semantic Scholar
Harnessing Artificial Intelligence for Enhanced Renal Analysis: Automated Detection of Hydronephrosis and Precise Kidney Segmentation
R. Alexa, Jennifer Kranz, R. Kramann, Christoph Kuppe +6 more
2024European Urology Open Science8 citations Open access
Semantic Scholar
Dissecting CD8+ T cell pathology of severe SARS-CoV-2 infection by single-cell epitope mapping
Felix Schreibing, M. Hannani, F. Ticconi, Eleanor Fewings +21 more
2021bioRxiv7 citations Open access
Semantic Scholar
Targeting Modulated Vascular Smooth Muscle Cells in Atherosclerosis via FAP-Directed Immunotherapy
Junedh M. Amrute, In-Hyuk Jung, Tracy Yamawaki, Andrea L. Bredemeyer +30 more
2025bioRxiv6 citations Open access
Semantic Scholar
Chromatin-accessibility estimation of single-cell on ATAC data
Zhijian Li, Christoph Kuppe, Susanne Ziegler, Mingbo Cheng +5 more
2019bioRxiv6 citations Open access
Semantic Scholar
Inhibition of the glucocorticoid receptor attenuates proteinuric kidney diseases in multiple species
E. Stamellou, S. Agrawal, F. Siegerist, Marc Buse +12 more
2023Nephrology, Dialysis and Transplantation5 citations Open access
Semantic Scholar
Defining Cardiac Recovery at Single Cell Resolution
Junedh M. Amrute, Lu-Lu Lai, Pan Ma, Andrew L. Koenig +16 more
2022bioRxiv5 citations Open access
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

R. Kramann×38
Invite
R. Kramann — researcher profile on SciRah
R. Schneider×13
Invite
R. Schneider — researcher profile on SciRah
J. Nagai×11
Invite
J. Nagai — researcher profile on SciRah
S. Hayat×11
Invite
S. Hayat — researcher profile on SciRah

×9

Invite

P. Boor — researcher profile on SciRah

Ivan G. Costa×8

Invite

Ivan G. Costa — researcher profile on SciRah

Junedh M. Amrute×8

Invite

Junedh M. Amrute — researcher profile on SciRah

Maurice Halder×7

Invite

Maurice Halder — researcher profile on SciRah

Sylvia Menzel×7

Invite

Sylvia Menzel — researcher profile on SciRah

J. Saez-Rodriguez×7

Invite

J. Saez-Rodriguez — researcher profile on SciRah

J. Sáez-Rodríguez×7

Invite

J. Sáez-Rodríguez — researcher profile on SciRah

Andrea L. Bredemeyer×7

Invite

Andrea L. Bredemeyer — researcher profile on SciRah