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S. Urbé · SciRah

Researcher profile · Semantic Scholar

S. Urbé

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S. Urbé — researcher profile on SciRah

h-index: 55
Works: 126
Citations: 19K

Most-cited papers

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
D. Klionsky, Amal Kamal Abdel-Aziz, Sara Abdelfatah, M. Abdellatif +496 more
2021Autophagy4,016 citations Open access
Semantic Scholar
Breaking the chains: structure and function of the deubiquitinases
D. Komander, M. J. Clague, S. Urbé
2009Nature reviews. Molecular cell biology2,117 citations
Semantic Scholar
The emerging shape of the ESCRT machinery
Roger L. Williams, S. Urbé
2007Nature reviews. Molecular cell biology781 citations
Semantic Scholar
Breaking the chains: deubiquitylating enzyme specificity begets function
M. J. Clague, S. Urbé, D. Komander
2019Nature reviews. Molecular cell biology747 citations
Semantic Scholar
Mammalian Atg18 (WIPI2) localizes to omegasome-anchored phagophores and positively regulates LC3 lipidation
H. Polson, J. de Lartigue, D. Rigden, M. Reedijk +3 more
2010Autophagy710 citations Open access
Semantic Scholar
Ubiquitin: same molecule, different degradation pathways.
M. J. Clague, S. Urbé
2010Cell513 citations Open access
Semantic Scholar
Molecular basis of USP7 inhibition by selective small molecule inhibitors
A. Turnbull, Stephanos Ioannidis, W. Krajewski, Adán Pinto-Fernández +39 more
2017Nature424 citations Open access
Semantic Scholar
Deubiquitylases from genes to organism.
M. J. Clague, I. Barsukov, J. Coulson, Han Liu +2 more
2013Physiological Reviews422 citations
Semantic Scholar
The demographics of the ubiquitin system.
M. J. Clague, Claire Heride, S. Urbé
2015Trends in Cell Biology332 citations
Semantic Scholar
Endocytosis: the DUB version.
M. J. Clague, S. Urbé
2006Trends in Cell Biology280 citations
Semantic Scholar
The Ubiquitin Isopeptidase UBPY Regulates Endosomal Ubiquitin Dynamics and Is Essential for Receptor Down-regulation*
P. E. Row, I. Prior, J. McCullough, M. J. Clague +1 more
2006Journal of Biological Chemistry261 citations Open access
Semantic Scholar
Cellular functions of the DUBs
M. J. Clague, J. Coulson, S. Urbé
2012Journal of Cell Science238 citations Open access
Semantic Scholar
Activation of the endosome-associated ubiquitin isopeptidase AMSH by STAM, a component of the multivesicular body-sorting machinery.
J. McCullough, P. E. Row, O. Lorenzo, Mary R. Doherty +3 more
2006Current Biology222 citations Open access
Semantic Scholar
PIKfyve Regulation of Endosome-Linked Pathways
J. de Lartigue, H. Polson, Morris E. Feldman, K. Shokat +3 more
2009Traffic : the International Journal of Intracellular Transport215 citations Open access
Semantic Scholar
Emerging roles of deubiquitinases in cancer‐associated pathways
J. Sacco, J. Coulson, M. J. Clague, S. Urbé
2010IUBMB Life - A Journal of the International Union of Biochemistry and Molecular Biology207 citations Open access
Semantic Scholar
Governance of endocytic trafficking and signaling by reversible ubiquitylation.
M. J. Clague, Han Liu, S. Urbé
2012Developmental Cell190 citations Open access
Semantic Scholar
The MIT Domain of UBPY Constitutes a CHMP Binding and Endosomal Localization Signal Required for Efficient Epidermal Growth Factor Receptor Degradation*
P. E. Row, Han Liu, Sebastian Hayes, R. Welchman +5 more
2007Journal of Biological Chemistry173 citations Open access
Semantic Scholar
USP30 deubiquitylates mitochondrial Parkin substrates and restricts apoptotic cell death
Jin-Rui Liang, Aitor Martinez, J. Lane, U. Mayor +2 more
2015EMBO Reports162 citations Open access
Semantic Scholar
Dual role of USP30 in controlling basal pexophagy and mitophagy
E. Marcassa, Andreas Kallinos, Jane Jardine, Emma V. Rusilowicz-Jones +5 more
2018EMBO Reports152 citations Open access
Semantic Scholar
Systematic characterization of deubiquitylating enzymes for roles in maintaining genome integrity
Ryotaro Nishi, P. Wijnhoven, C. le Sage, J. Tjeertes +5 more
2014Nature Cell Biology151 citations Open access
Semantic Scholar
Analysis of Articulation Between Clathrin and Retromer in Retrograde Sorting on Early Endosomes
V. Popoff, G. Mardones, Siau‐Kun Bai, Valérie Chambon +9 more
2009Traffic : the International Journal of Intracellular Transport126 citations
Semantic Scholar
Systematic survey of deubiquitinase localization identifies USP21 as a regulator of centrosome- and microtubule-associated functions
S. Urbé, Han Liu, Sebastian Hayes, Claire Heride +2 more
2012Molecular Biology of the Cell125 citations Open access
Semantic Scholar
Recruitment of UBPY and ESCRT exchange drive HD-PTP-dependent sorting of EGFR to the MVB.
N. Ali, Ling Zhang, Sandra Taylor, A. Mironov +2 more
2013Current Biology122 citations Open access
Semantic Scholar
USP30 sets a trigger threshold for PINK1–PARKIN amplification of mitochondrial ubiquitylation
Emma V. Rusilowicz-Jones, Jane Jardine, Andreas Kallinos, Adán Pinto-Fernández +25 more
2020Life Science Alliance117 citations Open access
Semantic Scholar
Ubiquitin code assembly and disassembly.
Claire Heride, S. Urbé, M. J. Clague
2014Current Biology97 citations Open access
Semantic Scholar
Systematic analysis of myotubularins: heteromeric interactions, subcellular localisation and endosomerelated functions
O. Lorenzo, S. Urbé, M. J. Clague
2006Journal of Cell Science95 citations Open access
Semantic Scholar
The deubiquitylase Ataxin-3 restricts PTEN transcription in lung cancer cells
J. Sacco, T. Yau, S. Darling, V. Patel +4 more
2013Oncogene78 citations Open access
Semantic Scholar
Protein degradation on the global scale.
Emma V. Rusilowicz-Jones, S. Urbé, M. J. Clague
2022Molecules and Cells71 citations Open access
Semantic Scholar
Quantitative proteomic analysis of Parkin substrates in Drosophila neurons
Aitor Martinez, B. Lectez, J. Ramírez, O. Popp +5 more
2017Molecular Neurodegeneration71 citations Open access
Semantic Scholar
Benchmarking a highly selective USP30 inhibitor for enhancement of mitophagy and pexophagy
Emma V. Rusilowicz-Jones, F. G. Barone, F. Lopes, Elezabeth Stephen +3 more
2021Life Science Alliance65 citations Open access
Semantic Scholar
A Chlamydia effector combining deubiquitination and acetylation activities induces Golgi fragmentation
J. Pruneda, Robert J. Bastidas, E. Bertsoulaki, Kirby N. Swatek +5 more
2018Nature Microbiology65 citations Open access
Semantic Scholar
Loss of the deubiquitylase BAP1 alters class I histone deacetylase expression and sensitivity of mesothelioma cells to HDAC inhibitors
J. Sacco, Jenna Kenyani, Z. Butt, Rachel J. Carter +7 more
2015OncoTarget62 citations Open access
Semantic Scholar
Deubiquitinase Activities Required for Hepatocyte Growth Factor-Induced Scattering of Epithelial Cells
R. Buus, Monica Faronato, D. Hammond, S. Urbé +1 more
2009Current Biology61 citations Open access
Semantic Scholar
FBXL4 ubiquitin ligase deficiency promotes mitophagy by elevating NIX levels
Hannah Elcocks, A. J. Brazel, Katy R. McCarron, M. Kaulich +4 more
2023EMBO Journal59 citations Open access
Semantic Scholar
HRS–WASH axis governs actin-mediated endosomal recycling and cell invasion
Ewan Macdonald, L. Brown, Arnaud Selvais, Han Liu +7 more
2018Journal of Cell Biology54 citations Open access
Semantic Scholar
Direct and Indirect Control of Mitogen-activated Protein Kinase Pathway-associated Components, BRAP/IMP E3 Ubiquitin Ligase and CRAF/RAF1 Kinase, by the Deubiquitylating Enzyme USP15
Sebastian Hayes, Han Liu, Ewan Macdonald, C. Sanderson +3 more
2012Journal of Biological Chemistry51 citations Open access
Semantic Scholar
USP28 deletion and small-molecule inhibition destabilizes c-MYC and elicits regression of squamous cell lung carcinoma
E. Ruiz, Adán Pinto-Fernández, A. Turnbull, Linxiang Lan +28 more
2020bioRxiv50 citations Open access
Semantic Scholar
Phosphoinositides and the endocytic pathway.
M. J. Clague, S. Urbé, J. de Lartigue
2009Experimental Cell Research50 citations
Semantic Scholar
Diverse routes to mitophagy governed by ubiquitylation and mitochondrial import.
Michael J. Clague, S. Urbé
2025Trends in Cell Biology49 citations Open access
Semantic Scholar
Regulation of ErbB2 Receptor Status by the Proteasomal DUB POH1
Han Liu, R. Buus, M. J. Clague, S. Urbé
2009PLoS ONE49 citations Open access
Semantic Scholar
Integration of cellular ubiquitin and membrane traffic systems: focus on deubiquitylases
M. J. Clague, S. Urbé
2017The FEBS Journal47 citations Open access
Semantic Scholar
Bimodal antagonism of PKA signalling by ARHGAP36
Rebecca L. Eccles, Maciej T. Czajkowski, Carolin Barth, Paul M. Müller +13 more
2016Nature Communications47 citations Open access
Semantic Scholar
The Deubiquitylase USP2 Regulates the LDLR Pathway by Counteracting the E3-Ubiquitin Ligase IDOL.
J. Nelson, V. Sorrentino, Rossella Avagliano Trezza, Claire Heride +3 more
2015Circulation Research47 citations Open access
Semantic Scholar
The deubiquitylase USP15 stabilizes newly synthesized REST and rescues its expression at mitotic exit
Monica Faronato, Vruti Patel, S. Darling, L. Dearden +3 more
2013Cell Cycle47 citations Open access
Semantic Scholar
Ubiquitin-dependent folding of the Wnt signaling coreceptor LRP6
E. Perrody, L. Abrami, Michal Feldman, B. Kunz +2 more
2016eLife45 citations Open access
Semantic Scholar
The centrosomal deubiquitylase USP21 regulates Gli1 transcriptional activity and stability
Claire Heride, D. Rigden, E. Bertsoulaki, D. Cucchi +3 more
2016Journal of Cell Science43 citations Open access
Semantic Scholar
The deubiquitylase USP9X controls ribosomal stalling
A. Clancy, Claire Heride, Adán Pinto-Fernández, Hannah Elcocks +22 more
2020bioRxiv41 citations Open access
Semantic Scholar
Multivesicular bodies.
M. J. Clague, S. Urbé
2008Current Biology41 citations Open access
Semantic Scholar
USP8 Controls the Trafficking and Sorting of Lysosomal Enzymes
Ewan Macdonald, S. Urbé, M. J. Clague
2014Traffic : the International Journal of Intracellular Transport36 citations
Semantic Scholar
The deubiquitylase USP15 regulates topoisomerase II alpha to maintain genome integrity
Andrew B. Fielding, M. Concannon, S. Darling, Emma V. Rusilowicz-Jones +5 more
2018Oncogene35 citations Open access
Semantic Scholar

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