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L. Abrami · SciRah

Researcher profile · Semantic Scholar

L. Abrami

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L. Abrami — researcher profile on SciRah

h-index: 44
Works: 102
Citations: 7,502

Most-cited papers

Targeting STING with covalent small-molecule inhibitors
S. M. Haag, M. F. Gulen, L. Reymond, Antoine Gibelin +7 more
2018Nature1,085 citations Open access
Semantic Scholar
Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival.
L. Gurcel, L. Abrami, S. Girardin, Jürg Tschopp +1 more
2006Cell542 citations Open access
Semantic Scholar
Anthrax toxin triggers endocytosis of its receptor via a lipid raft–mediated clathrin-dependent process
L. Abrami, Shihui Liu, P. Cosson, S. Leppla +1 more
2003Journal of Cell Biology497 citations Open access
Semantic Scholar
Mitogen-activated protein kinase pathways defend against bacterial pore-forming toxins.
Danielle L Huffman, L. Abrami, R. Sásik, J. Corbeil +2 more
2004Proceedings of the National Academy of Sciences of the United States of America334 citations Open access
Semantic Scholar
SwissPalm: Protein Palmitoylation database
M. Blanc, F. David, L. Abrami, D. Migliozzi +3 more
2015F1000Research253 citations Open access
Semantic Scholar
Differential sorting and fate of endocytosed GPI‐anchored proteins
M. Fivaz, F. Vilbois, Sarah Thurnheer, C. Pasquali +4 more
2002EMBO Journal240 citations Open access
Semantic Scholar
Membrane insertion of anthrax protective antigen and cytoplasmic delivery of lethal factor occur at different stages of the endocytic pathway
L. Abrami, Margaret R. Lindsay, R. Parton, S. Leppla +1 more
2004Journal of Cell Biology225 citations Open access
Semantic Scholar
A Pore-forming Toxin Interacts with a GPI-anchored Protein and Causes Vacuolation of the Endoplasmic Reticulum
L. Abrami, M. Fivaz, Pierre-Etienne Glauser, R. Parton +1 more
1998Journal of Cell Biology218 citations Open access
Semantic Scholar
Mechanisms and functions of protein S-acylation
Francisco S. Mesquita, L. Abrami, M. Linder, S. Bamji +2 more
2024Nature reviews. Molecular cell biology214 citations Open access
Semantic Scholar
Receptor palmitoylation and ubiquitination regulate anthrax toxin endocytosis
L. Abrami, S. Leppla, F. Gisou van der Goot
2006Journal of Cell Biology212 citations Open access
Semantic Scholar
Hijacking multivesicular bodies enables long-term and exosome-mediated long-distance action of anthrax toxin
L. Abrami, L. Brandi, M. Moayeri, Michael J. Brown +3 more
2013Cell Reports203 citations Open access
Semantic Scholar
Palmitoylated calnexin is a key component of the ribosome–translocon complex
Asvin K. K. Lakkaraju, L. Abrami, T. Lemmin, Sanja Blaskovic +4 more
2012EMBO Journal186 citations Open access
Semantic Scholar
Palmitoylation and ubiquitination regulate exit of the Wnt signaling protein LRP6 from the endoplasmic reticulum
L. Abrami, B. Kunz, I. Iacovache, F. Gisou van der Goot
2008Proceedings of the National Academy of Sciences of the United States of America172 citations Open access
Semantic Scholar
Role for Human Immunodeficiency Virus Type 1 Membrane Cholesterol in Viral Internalization
M. Guyader, E. Kiyokawa, L. Abrami, P. Turelli +1 more
2002Journal of Virology171 citations Open access
Semantic Scholar
Plasma Membrane Microdomains Act as Concentration Platforms to Facilitate Intoxication by Aerolysin
L. Abrami, F. Gisou van der Goot
1999Journal of Cell Biology161 citations Open access
Semantic Scholar
Anthrax toxin: the long and winding road that leads to the kill.
L. Abrami, N. Reig, F. Gisou van der Goot
2005Trends in Microbiology153 citations Open access
Semantic Scholar
Membrane insertion: The strategies of toxins (review).
C. Lesieur, B. Vécsey-Semjén, L. Abrami, M. Fivaz +1 more
1997Molecular membrane biology152 citations Open access
Semantic Scholar
The Pore-forming Toxin Proaerolysin Is Activated by Furin*
L. Abrami, M. Fivaz, E. Decroly, N. Seidah +5 more
1998Journal of Biological Chemistry151 citations Open access
Semantic Scholar
Adventures of a pore-forming toxin at the target cell surface.
L. Abrami, M. Fivaz, F. Gisou van der Goot
2000Trends in Microbiology135 citations Open access
Semantic Scholar
S-acylation controls SARS-CoV-2 membrane lipid organization and enhances infectivity
F. Mesquita, L. Abrami, O. Sergeeva, P. Turelli +10 more
2021bioRxiv131 citations Open access
Semantic Scholar
Bacterial subversion of lipid rafts.
F. Lafont, L. Abrami, F. Gisou van der Goot
2004Current Opinion in Microbiology108 citations Open access
Semantic Scholar
Endocytosis of the Anthrax Toxin Is Mediated by Clathrin, Actin and Unconventional Adaptors
L. Abrami, Mirko Bischofberger, B. Kunz, Romain Groux +1 more
2010PLoS Pathogens104 citations Open access
Semantic Scholar
Hrs and SNX3 Functions in Sorting and Membrane Invagination within Multivesicular Bodies
V. Pons, Pierre-Philippe Luyet, E. Morel, L. Abrami +3 more
2008PLoS Biology99 citations Open access
Semantic Scholar
Cross-talk between Caveolae and Glycosylphosphatidylinositol-rich Domains*
L. Abrami, M. Fivaz, Toshihide Kobayashi, T. Kinoshita +2 more
2001Journal of Biological Chemistry89 citations Open access
Semantic Scholar
Palmitoylation mediates membrane association of hepatitis E virus ORF3 protein and is required for infectious particle secretion
J. Gouttenoire, Ángela Pollán, L. Abrami, Noémie Oechslin +7 more
2018PLoS Pathogens86 citations Open access
Semantic Scholar
Landing on lipid rafts.
M. Fivaz, L. Abrami, F. Gisou van der Goot
1999Trends in Cell Biology83 citations Open access
Semantic Scholar
CMG2/ANTXR2 regulates extracellular collagen VI which accumulates in hyaline fibromatosis syndrome
J. Bürgi, B. Kunz, L. Abrami, J. Deuquet +7 more
2017Nature Communications80 citations Open access
Semantic Scholar
Palmitoylated acyl protein thioesterase APT2 deforms membranes to extract substrate acyl chains
L. Abrami, M. Audagnotto, Sylvia Ho, M. Marcaida +7 more
2021Nature Chemical Biology65 citations Open access
Semantic Scholar
Figures and figure supplements Identification and dynamics of the human ZDHHC 16-ZDHHC 6 palmitoylation cascade
L. Abrami
201861 citations
Semantic Scholar
Sensitivity of Polarized Epithelial Cells to the Pore-Forming Toxin Aerolysin
L. Abrami, M. Fivaz, Pierre-Etienne Glauser, N. Sugimoto +2 more
2003Infection and Immunity59 citations Open access
Semantic Scholar
Hyaline Fibromatosis Syndrome inducing mutations in the ectodomain of anthrax toxin receptor 2 can be rescued by proteasome inhibitors
J. Deuquet, E. Lausch, N. Guex, L. Abrami +8 more
2011EMBO Molecular Medicine58 citations Open access
Semantic Scholar
Entry of the Lymphogranuloma Venereum Strain of Chlamydia trachomatis into Host Cells Involves Cholesterol-Rich Membrane Domains
I. Jutras, L. Abrami, A. Dautry-Varsat
2003Infection and Immunity58 citations Open access
Semantic Scholar
Local and substrate-specific S-palmitoylation determines subcellular localization of Gαo
Gonzalo P. Solis, A. Kazemzadeh, L. Abrami, J. Valnohova +3 more
2020Nature Communications57 citations Open access
Semantic Scholar
Anthrax toxin receptor 2a controls mitotic spindle positioning
I. Castanon, L. Abrami, L. Holtzer, C. Heisenberg +2 more
2012Nature Cell Biology52 citations Open access
Semantic Scholar
Anthrax toxin triggers the activation of src-like kinases to mediate its own uptake
L. Abrami, B. Kunz, F. Gisou van der Goot
2010Proceedings of the National Academy of Sciences of the United States of America52 citations Open access
Semantic Scholar
Aerolysin from Aeromonas hydrophila and related toxins.
M. Fivaz, L. Abrami, Yulia Tsitrin, F. Gisou van der Goot
2001Current Topics in Microbiology and Immunology51 citations Open access
Semantic Scholar
Identification and dynamics of the human ZDHHC16-ZDHHC6 palmitoylation cascade
L. Abrami, T. Dallavilla, P. A. Sandoz, Mustafa Demir +4 more
2017eLife49 citations Open access
Semantic Scholar
A toxic palmitoylation of Cdc42 enhances NF-κB signaling and drives a severe autoinflammatory syndrome.
Bahia Bekhouche, Aurore Tourville, Y. Ravichandran, R. Tacine +24 more
2020Journal of Allergy and Clinical Immunology47 citations Open access
Semantic Scholar
The glycan core of GPI‐anchored proteins modulates aerolysin binding but is not sufficient: the polypeptide moiety is required for the toxin–receptor interaction
L. Abrami, Marie-Claire Velluz, Yeongjin Hong, K. Ohishi +4 more
2002FEBS Letters47 citations Open access
Semantic Scholar
Not as simple as just punching a hole.
M. Fivaz, L. Abrami, Yulia Tsitrin, F. Gisou van der Goot
2001Toxicon46 citations Open access
Semantic Scholar
Ubiquitin-dependent folding of the Wnt signaling coreceptor LRP6
E. Perrody, L. Abrami, Michal Feldman, B. Kunz +2 more
2016eLife45 citations Open access
Semantic Scholar
Sendai virus budding in the course of an infection does not require Alix and VPS4A host factors.
A. Gosselin-Grenet, J. Marq, L. Abrami, D. Garcin +1 more
2007Virology45 citations Open access
Semantic Scholar
Functional interactions between anthrax toxin receptors and the WNT signalling protein LRP6
L. Abrami, B. Kunz, J. Deuquet, A. Bafico +2 more
2008Cellular Microbiology44 citations Open access
Semantic Scholar
Model-Driven Understanding of Palmitoylation Dynamics: Regulated Acylation of the Endoplasmic Reticulum Chaperone Calnexin
T. Dallavilla, L. Abrami, P. A. Sandoz, Georgios Savoglidis +2 more
2016PLoS Comput. Biol.43 citations Open access
Semantic Scholar
S-acylation by ZDHHC20 targets ORAI1 channels to lipid rafts for efficient Ca2+ signaling by Jurkat T cell receptors at the immune synapse
Amado Carreras-Sureda, L. Abrami, Ji-Hee Kim, Wen-An Wang +5 more
2021eLife40 citations Open access
Semantic Scholar
ER-Golgi-localized proteins TMED2 and TMED10 control the formation of plasma membrane lipid nanodomains.
Muhammad U Anwar, O. Sergeeva, L. Abrami, F. Mesquita +7 more
2022Developmental Cell38 citations Open access
Semantic Scholar
Systemic hyalinosis mutations in the CMG2 ectodomain leading to loss of function through retention in the endoplasmic reticulum
J. Deuquet, L. Abrami, A. DiFeo, M. C. Ramirez +2 more
2009Human Mutation34 citations Open access
Semantic Scholar
Functional differentiation of the human red blood cell and kidney urea transporters.
S. Martial, Bernadette Olivès, L. Abrami, Cécile Couriaud +6 more
1996American Journal of Physiology33 citations
Semantic Scholar
Akt Is S-Palmitoylated: A New Layer of Regulation for Akt
M. Blaustein, E. Piegari, Camila Martinez Calejman, Antonella Vila +9 more
2021Frontiers in Cell and Developmental Biology32 citations Open access
Semantic Scholar
Hemagglutinin of Influenza A, but not of Influenza B and C viruses is acylated by ZDHHC2, 8, 15 and 20
M. R. Gadalla, L. Abrami, F. Gisou van der Goot, M. Veit
2019bioRxiv29 citations Open access
Semantic Scholar

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