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M. Waddingham · SciRah

Researcher profile · Semantic Scholar

M. Waddingham

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M. Waddingham — researcher profile on SciRah

h-index: 12
Works: 39
Citations: 450

Most-cited papers

Nitrosative Stress as a Modulator of Inflammatory Change in a Model of Takotsubo Syndrome
S. Surikow, T. H. Nguyen, I. Stafford, M. Chapman +12 more
2018JACC: Basic to Translational Science61 citations Open access
Semantic Scholar
Contractile apparatus dysfunction early in the pathophysiology of diabetic cardiomyopathy.
M. Waddingham, A. Edgley, H. Tsuchimochi, D. Kelly +2 more
2015World Journal of Diabetes57 citations Open access
Semantic Scholar
Liraglutide treatment improves the coronary microcirculation in insulin resistant Zucker obese rats on a high salt diet
V. Sukumaran, H. Tsuchimochi, T. Sonobe, M. Waddingham +2 more
2020Cardiovascular Diabetology50 citations Open access
Semantic Scholar
Acute Rho-kinase inhibition improves coronary dysfunction in vivo, in the early diabetic microcirculation
J. Pearson, M. Jenkins, A. Edgley, T. Sonobe +9 more
2013Cardiovascular Diabetology45 citations Open access
Semantic Scholar
CaMKII activity contributes to Homeometric Autoregulation of the heart: a novel mechanism for the Anrep effect
J. Reil, G. Reil, Á. Kov́acs, V. Sequeira +16 more
2020Journal of Physiology39 citations Open access
Semantic Scholar
Pulmonary Hypertension Is Associated With a Higher Risk of Heart Failure Hospitalization and Mortality in Patients With Chronic Kidney Disease: The Jackson Heart Study
M. Waddingham, W. Paulus, J. Myers, P. Kokkinos +50 more
2017Circulation: Heart Failure38 citations Open access
Semantic Scholar
Diastolic dysfunction is initiated by cardiomyocyte impairment ahead of endothelial dysfunction due to increased oxidative stress and inflammation in an experimental prediabetes model.
M. Waddingham, T. Sonobe, H. Tsuchimochi, A. Edgley +17 more
2019Journal of Molecular and Cellular Cardiology31 citations Open access
Semantic Scholar
Mechano-energetic uncoupling in hypertrophic cardiomyopathy: Pathophysiological mechanisms and therapeutic opportunities
V. Sequeira, M. Waddingham, H. Tsuchimochi, C. Maack +1 more
2023Journal of Molecular and Cellular Cardiology Plus22 citations Open access
Semantic Scholar
Chronic Rho-kinase inhibition improves left ventricular contractile dysfunction in early type-1 diabetes by increasing myosin cross-bridge extension
M. Waddingham, A. Edgley, A. Astolfo, T. Inagaki +8 more
2015Cardiovascular Diabetology16 citations Open access
Semantic Scholar
Beta-blockade Prevents Coronary Macro and Microvascular Dysfunction Induced by a High Salt Diet and Insulin Resistance in the Goto-Kakizaki Rat.
James T. Pearson, H. Thambyah, M. Waddingham, T. Inagaki +13 more
2021Clinical science15 citations
Semantic Scholar
Widespread Coronary Dysfunction in the Absence of HDL Receptor SR-B1 in an Ischemic Cardiomyopathy Mouse Model
J. Pearson, M. Yoshimoto, Yi-Ching Chen, Rohullah Sultani +14 more
2017Scientific Reports15 citations Open access
Semantic Scholar
Prognostic value of right ventricular native T1 mapping in pulmonary arterial hypertension
R. Asano, T. Ogo, Y. Morita, A. Kotoku +12 more
2021PLoS ONE13 citations Open access
Semantic Scholar
Ghrelin and vascular protection
J. Pearson, M. Shirai, V. Sukumaran, Cheng-Kun Du +5 more
2019Vascular Biology11 citations Open access
Semantic Scholar
Hypercontractility and Oxidative Stress Drive Creatine Kinase Dysfunction in Hypertrophic Cardiomyopathy
Anton Xu, David Weissman, K. Ermer, E. Bertero +26 more
2025Circulation10 citations Open access
Semantic Scholar
Microvascular Paradigm in Heart Failure With Preserved Ejection Fraction: A Quest for Proof of Concept
M. Waddingham, W. Paulus
2017Circulation: Heart Failure8 citations Open access
Semantic Scholar
Myosin motor dynamics and cardiac function: Insights from in vivo small‐angle X‐ray scattering and pressure–volume analysis
James T. Pearson, M. Waddingham, H. Tsuchimochi, Takashi Sonobe +7 more
2025Journal of Physiology4 citations Open access
Semantic Scholar
Geranylgeranylacetone reduces cardiomyocyte stiffness and attenuates diastolic dysfunction in a rat model of cardiometabolic syndrome
M. Waddingham, V. Sequeira, D. Kuster, E. Dal Canto +9 more
2023Physiological Reports4 citations Open access
Semantic Scholar
Racial Tension in Hypertension: Divergent Effects of African and European Ancestry on Cardiac Remodeling.
W. Paulus, M. Waddingham
2017JACC. Heart failure4 citations Open access
Semantic Scholar
The selective serotonin reuptake inhibitor paroxetine improves right ventricular systolic function in experimental pulmonary hypertension
M. Waddingham, H. Tsuchimochi, Takashi Sonobe, V. Sequeira +4 more
2024Journal of Molecular and Cellular Cardiology Plus3 citations Open access
Semantic Scholar
Mavacamten Versus Alcohol Septal Ablation in Obstructive Hypertrophic Cardiomyopathy: An Echocardiography-Derived Pressure-Volume Analysis.
J. Reil, V. Sequeira, C. Coppée, Karina Peters +7 more
2026Circulation: Heart Failure2 citations
Semantic Scholar
Using Synchrotron Radiation Imaging Techniques to Elucidate the Actions of Hexarelin in the Heart of Small Animal Models
M. Waddingham, H. Tsuchimochi, T. Sonobe, R. Asano +11 more
2022Frontiers in Physiology2 citations Open access
Semantic Scholar
Role of S1P‐ and Rho‐kinase signalling in age‐related myogenic tone deficiency in murine resistance arteries
G. Skovsted, A. Aupetit, Karl Björling, Kristian A. Haanes +8 more
2025Experimental Physiology1 citations Open access
Semantic Scholar
Hypercontractility-driven oxidative stress impairs creatine kinase function in hypertrophic cardiomyopathy
Anton Xu, David Weissman, K. Ermer, M. Kohlhaas +10 more
2026Journal of Molecular and Cellular Cardiology Plus0 citations Open access
Semantic Scholar
A muscle-enriched mitochondrial protein regulates postnatal heart growth through mitonuclear ubiquinone-PPAR signaling.
Kentaro Hirose, Xiao-Xin Chen, C. Kalyanaraman, M. Waddingham +27 more
2026Proceedings of the National Academy of Sciences of the United States of America0 citations Open access
Semantic Scholar
Induction of ischaemic cardiomyopathy in mice without off‐target effects
M. Waddingham, James T. Pearson
2025Experimental Physiology0 citations Open access
Semantic Scholar
Linking Myocardium Hypercontractility to Microvasculature Dysfunction and Inflammation through NLRP3 Inflammasome Activation
V. Sequeira, K. Ermer, Jan M. Federspiel, M. Waddingham +4 more
2024Journal of Molecular and Cellular Cardiology Plus0 citations Open access
Semantic Scholar
Abstract 9592: The Super Relaxed State of Myosin Contributes to the Pathogenesis of Right Ventricular Dysfunction in Pulmonary Hypertension
M. Waddingham, H. Tsuchimochi, R. Asano, T. Sonobe +5 more
2022Circulation0 citations
Semantic Scholar
EFFECTS OF A GLUCAGON LIKE PEPTIDE-1 AGONIST AND RHO-KINASE INHIBITOR ON PULMONARY AND RIGHT VENTRICLE FUNCTION IN PULMONARY HYPERTENSIVE RATS WITH AND WITHOUT INSULIN RESISTANCE
J. Pearson, Hui Jin, M. Waddingham, T. Sonobe +8 more
20210 citations Open access
Semantic Scholar
Boosting small heat shock proteins lowers cardiomyocyte passive stiffness in experimental heart failure with preserved ejection fraction
M. Waddingham, E. Dal Canto, D. Da Silva Goncalves Bos, V. Sequeria +7 more
20180 citations
Semantic Scholar
Plasma natriuretic peptides relate to distinct patterns of left ventricular dysfunction in chronic HFpEF
E. Dal Canto, L. van Heerebeek, K. Kortekaas, M. Waddingham +1 more
2018Journal of Molecular and Cellular Cardiology0 citations
Semantic Scholar
Abstract 20081: Distinct Signaling Pathways Mediate Phosphorylation of Sarcomeric Proteins in the Right and Left Ventricle of the Failing Heart
Á. Kov́acs, M. Waddingham, D. Kolijn, J. Barta +6 more
20170 citations
Semantic Scholar
P3473Effect of insulin resistance on compound 21 mediated coronary microvascular dilation in female rats in vivo
J. Pearson, P. Meagher, H. Tsuchimochi, A. Edgley +9 more
20170 citations
Semantic Scholar
P3478Beta-blockade prevents coronary microvascular endothelial dysfunction in non-obese salt-sensitive insulin resistant rats on a high salt diet
H. Tsuchimochi, H. Thambyah, A. Edgley, T. Inagaki +9 more
20170 citations
Semantic Scholar
Contractile dysfunction of the heart in early diabetes
M. Waddingham
20160 citations
Semantic Scholar
CARDIAC ACTIN-MYOSIN CROSS-BRIDGE DYSREGULATION OCCURS EARLY IN THE PATHOGENESIS OF TYPE 2 DIABETIC CARDIOMYOPATHY
M. Waddingham, A. Edgley, T. Inagaki, H. Tsuchimochi +4 more
20150 citations
Semantic Scholar
Rho Kinase Inhibition Improves Cardiac Cross‐Bridge Dynamics in Early Diabetic Cardiomyopathy
M. Waddingham, A. Edgley, A. Astolfo, T. Inagaki +6 more
20150 citations
Semantic Scholar
Rho Kinase Inhibition Improves Cross Bridge Cycling In Early Diabetic Heart Disease
M. Waddingham, A. Edgley, A. Astolfo, T. Inagaki +5 more
20130 citations Open access
Semantic Scholar
O R I G I N a L I N V E S T I G a T I O N Open Access
J. Pearson, M. Jenkins, A. Edgley, T. Sonobe +9 more
0 citations
Semantic Scholar
Beta-blockade prevents coronary microvascular endothelial dysfunction in non-obese salt-sensitive insulin resistant rats on a high salt diet
H. Tsuchimochi, H. Thambyah, A. Edgley, T. Inagaki +14 more
0 citations
Semantic Scholar

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