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V. Sequeira · SciRah

Researcher profile · Semantic Scholar

V. Sequeira

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V. Sequeira — researcher profile on SciRah

h-index: 25
Works: 110
Citations: 1,912

Most-cited papers

The physiological role of cardiac cytoskeleton and its alterations in heart failure.
V. Sequeira, L. Nijenkamp, J. Regan, J. van der Velden
2014Biochimica et Biophysica Acta179 citations Open access
Semantic Scholar
β‐adrenergic receptor signalling and its functional consequences in the diseased heart
A. Najafi, V. Sequeira, D. Kuster, J. van der Velden
2016European Journal of Clinical Investigation106 citations Open access
Semantic Scholar
Historical perspective on heart function: the Frank–Starling Law
V. Sequeira, J. van der Velden
2015Biophysical Reviews97 citations Open access
Semantic Scholar
Metabolic changes in hypertrophic cardiomyopathies: scientific update from the Working Group of Myocardial Function of the European Society of Cardiology
J. van der Velden, C. Tocchetti, G. Varricchi, Anna Bianco +10 more
2018Cardiovascular Research93 citations Open access
Semantic Scholar
Hypertrophic Cardiomyopathy: A Vicious Cycle Triggered by Sarcomere Mutations and Secondary Disease Hits.
P. Wijnker, V. Sequeira, D. Kuster, J. van der Velden
2019Antioxidants and Redox Signaling81 citations Open access
Semantic Scholar
Synergistic role of ADP and Ca2+ in diastolic myocardial stiffness
V. Sequeira, A. Najafi, Mark McConnell, E. Fowler +9 more
2015Journal of Physiology72 citations Open access
Semantic Scholar
Loss of Mitochondrial Ca2+ Uniporter Limits Inotropic Reserve and Provides Trigger and Substrate for Arrhythmias in Barth Syndrome Cardiomyopathy
E. Bertero, A. Nickel, M. Kohlhaas, M. Hohl +24 more
2021Circulation49 citations Open access
Semantic Scholar
ADP-stimulated contraction: A predictor of thin-filament activation in cardiac disease
V. Sequeira, A. Najafi, P. Wijnker, C. dos Remedios +3 more
2015Proceedings of the National Academy of Sciences of the United States of America48 citations Open access
Semantic Scholar
Length-dependent activation is modulated by cardiac troponin I bisphosphorylation at Ser23 and Ser24 but not by Thr143 phosphorylation.
P. Wijnker, V. Sequeira, D. B. Foster, Yuejin Li +4 more
2014American Journal of Physiology. Heart and Circulatory Physiology48 citations Open access
Semantic Scholar
Energetic drain driving hypertrophic cardiomyopathy
V. Sequeira, E. Bertero, C. Maack
2019FEBS Letters46 citations Open access
Semantic Scholar
Mechano-energetic uncoupling in heart failure
D. Aksentijević, S. Sedej, J. Fauconnier, Mélanie Paillard +9 more
2025Nature Reviews Cardiology45 citations Open access
Semantic Scholar
The CaMKII inhibitor KN93-calmodulin interaction and implications for calmodulin tuning of NaV1.5 and RyR2 function
Christopher N. Johnson, R. Pattanayek, F. Potet, Robyn T. Rebbeck +12 more
2019Cell Calcium44 citations Open access
Semantic Scholar
The Frank–Starling Law: a jigsaw of titin proportions
V. Sequeira, J. van der Velden
2017Biophysical Reviews44 citations Open access
Semantic Scholar
Distinctive patterns of inflammation across the heart failure syndrome
G. Schiattarella, V. Sequeira, Pietro Ameri
2020Heart Failure Reviews40 citations
Semantic Scholar
CaMKII activity contributes to Homeometric Autoregulation of the heart: a novel mechanism for the Anrep effect
J. Reil, G. Reil, Á. Kov́acs, V. Sequeira +16 more
2020Journal of Physiology39 citations Open access
Semantic Scholar
CaMKII does not control mitochondrial Ca2+ uptake in cardiac myocytes
A. Nickel, M. Kohlhaas, E. Bertero, Daniel Wilhelm +9 more
2020Journal of Physiology36 citations
Semantic Scholar
Selective phosphorylation of PKA targets after β-adrenergic receptor stimulation impairs myofilament function in Mybpc3-targeted HCM mouse model.
A. Najafi, V. Sequeira, M. Helmes, I. Bollen +5 more
2016Cardiovascular Research34 citations Open access
Semantic Scholar
Stress activated signalling impaired protein quality control pathways in human hypertrophic cardiomyopathy.
R. Hassoun, H. Budde, S. Zhazykbayeva, M. Herwig +19 more
2021International Journal of Cardiology33 citations Open access
Semantic Scholar
Hemodynamic Assessment in Takotsubo Syndrome.
T. Stiermaier, J. Reil, V. Sequeira, E. Rawish +8 more
2023Journal of the American College of Cardiology30 citations Open access
Semantic Scholar
Metabolic Alterations in Inherited Cardiomyopathies
Claudia Sacchetto, V. Sequeira, E. Bertero, Jan Dudek +2 more
2019Journal of Clinical Medicine29 citations Open access
Semantic Scholar
The Interplay between S-Glutathionylation and Phosphorylation of Cardiac Troponin I and Myosin Binding Protein C in End-Stage Human Failing Hearts
H. Budde, R. Hassoun, M. Tangos, S. Zhazykbayeva +17 more
2021Antioxidants26 citations Open access
Semantic Scholar
Integrating Clinical Phenotype With Multiomics Analyses of Human Cardiac Tissue Unveils Divergent Metabolic Remodeling in Genotype-Positive and Genotype-Negative Patients With Hypertrophic Cardiomyopathy
E. Nollet, M. Schuldt, V. Sequeira, Aleksandra Binek +15 more
2024Circulation Genomic and Precision Medicine25 citations Open access
Semantic Scholar
Exploring the Connection Between Relaxed Myosin States and the Anrep Effect
V. Sequeira, C. Maack, Gert-Hinrich Reil, J. Reil
2024Circulation Research25 citations
Semantic Scholar
Effect of levosimendan on the contractility of muscle fibers from nemaline myopathy patients with mutations in the nebulin gene
J. D. de Winter, B. Joureau, V. Sequeira, N. Clarke +5 more
2015Skeletal Muscle25 citations Open access
Semantic Scholar
Mechano-energetic uncoupling in hypertrophic cardiomyopathy: Pathophysiological mechanisms and therapeutic opportunities
V. Sequeira, M. Waddingham, H. Tsuchimochi, C. Maack +1 more
2023Journal of Molecular and Cellular Cardiology Plus22 citations Open access
Semantic Scholar
Phosphorylation of protein kinase C sites Ser42/44 decreases Ca2+-sensitivity and blunts enhanced length-dependent activation in response to protein kinase A in human cardiomyocytes
P. Wijnker, V. Sequeira, E. R. Witjas-Paalberends, D. B. Foster +4 more
2014Archives of Biochemistry and Biophysics16 citations Open access
Semantic Scholar
Effects of NPY-2 Receptor Antagonists, Semaglutide, PYY3-36, and Empagliflozin on Early MASLD in Diet-Induced Obese Rats
S. Kloock, Niklas Haerting, Gloria Herzog, Marie Oertel +7 more
2024Nutrients14 citations Open access
Semantic Scholar
Targeting mitochondria in hypertrophic cardiomyopathy.
V. Sequeira, A. Batzner, C. Maack
2023European Heart Journal14 citations
Semantic Scholar
Investigating the Anrep Effect in Hypertrophic Obstructive Cardiomyopathy With Invasive Pressure-Volume Analysis
J. Reil, V. Sequeira, Gert-Hinrich Reil, S. Scholtz +4 more
2025JACC: Advances13 citations Open access
Semantic Scholar
Nitro-oleic acid enhances mitochondrial metabolism and ameliorates heart failure with preserved ejection fraction in mice
Marion Müller, T. Schubert, Cornelius Welke, Tibor Maske +24 more
2025Nature Communications13 citations Open access
Semantic Scholar
Assessing Rodent Cardiac Function in vivo Using Hemodynamic Pressure-Volume Loops
D. Miranda-Silva, V. Sequeira, A. Lourenço, I. Falcão-Pires
2022Frontiers in Physiology12 citations Open access
Semantic Scholar
Hungry Hearts.
E. Bertero, V. Sequeira, C. Maack
2018Circulation: Heart Failure12 citations
Semantic Scholar
GLP-1 and PYY for the treatment of obesity: a pilot study on the use of agonists and antagonists in diet-induced rats
Marie Oertel, Christian G Ziegler, M. Kohlhaas, Alexander Nickel +5 more
2024Endocrine Connections11 citations Open access
Semantic Scholar
Hypercontractility and Oxidative Stress Drive Creatine Kinase Dysfunction in Hypertrophic Cardiomyopathy
Anton Xu, David Weissman, K. Ermer, E. Bertero +26 more
2025Circulation10 citations Open access
Semantic Scholar
Semaglutide normalizes increased cardiomyocyte calcium transients in a rat model of high fat diet‐induced obesity
V. Sequeira, Julia Theisen, K. Ermer, Marie Oertel +9 more
2024ESC Heart Failure10 citations Open access
Semantic Scholar
Mavacamten maintenance dose determination: insights into individualised therapy for hypertrophic cardiomyopathy
S. Scholtz, C. Coppée, K. Mohemed, M. Potratz +4 more
2025Open Heart9 citations Open access
Semantic Scholar
Ketogenic diet and ketone salts differentially improve cardiometabolic complications in an HFpEF rat model
Alexandre Gonçalves, Inês N. Alves, C. Mendes, Daniela Miranda +14 more
2025Journal of Physiology8 citations Open access
Semantic Scholar
Myosin-Inhibitor Mavacamten Acutely Enhances Cardiomyocyte Diastolic Compliance in Heart Failure With Preserved Ejection Fraction.
J. Almeida-Coelho, A. Leite-Moreira, V. Sequeira, N. Hamdani +3 more
2024Circulation: Heart Failure7 citations
Semantic Scholar
Tropomyosin-troponin complex in inherited cardiomyopathies.
Christian Krijger Juárez, V. Sequeira, M. van den Boogaard, C. Veerman +7 more
2024Heart Rhythm6 citations Open access
Semantic Scholar
Mitochondrial reactive oxygen species cause arrhythmias in hypertrophic cardiomyopathy
M. Kohlhaas, V. Sequeira, S. Parikh, Alexander Dietl +26 more
2024bioRxiv6 citations Open access
Semantic Scholar
Rebalancing protein phosphorylation in heart failure to prevent arrhythmias
V. Sequeira, C. Maack
2018European Journal of Heart Failure6 citations Open access
Semantic Scholar
Activation of the Anrep Effect in Aortic Stenosis Pre-TAVR and Post-TAVR
J. Reil, V. Sequeira, Philip Lucas, Lea Tadros +10 more
2025JACC: Advances4 citations Open access
Semantic Scholar
Metabolic alterations in human hypertrophic cardiomyopathy
E. Nollet, V. Sequeira, Christoph Maack, J. Ochala +1 more
2025The Journal of Cardiovascular Aging4 citations Open access
Semantic Scholar
Myosin motor dynamics and cardiac function: Insights from in vivo small‐angle X‐ray scattering and pressure–volume analysis
James T. Pearson, M. Waddingham, H. Tsuchimochi, Takashi Sonobe +7 more
2025Journal of Physiology4 citations Open access
Semantic Scholar
Geranylgeranylacetone reduces cardiomyocyte stiffness and attenuates diastolic dysfunction in a rat model of cardiometabolic syndrome
M. Waddingham, V. Sequeira, D. Kuster, E. Dal Canto +9 more
2023Physiological Reports4 citations Open access
Semantic Scholar
Low expression of the K280N TNNT2 mutation is sufficient to increase basal myofilament activation in human hypertrophy cardiomyopathy
V. Sequeira, Lili Wang, P. Wijnker, Kyungsoo Kim +5 more
2022Journal of Molecular and Cellular Cardiology Plus4 citations Open access
Semantic Scholar
Reduced left ventricular contractility, increased diastolic operant stiffness and high energetic expenditure in patients with severe aortic regurgitation without indication for surgery.
J. Reil, G. Reil, N. Hecker, V. Sequeira +11 more
2020Interactive Cardiovascular and Thoracic Surgery4 citations Open access
Semantic Scholar
Data rate change algorithms for efficient HF communications
V. Sequeira, M. P. Queluz, António Rodrigues, J. Sanguino +1 more
20182018 International Conference on Military Communications and Information Systems (ICMCIS)4 citations
Semantic Scholar
Mavacamten optimizes myocardial work in patients with obstructive hypertrophic cardiomyopathy: a non-invasive pressure–strain analysis
S. Scholtz, C. Coppée, K. Mohemed, M. Potratz +6 more
2026Clinical Research in Cardiology3 citations Open access
Semantic Scholar
The Anrep effect in septic shock: a mechanism of cardiac adaptation.
V. Sequeira, C. Maack, Gert-Hinrich Reil, J. Reil
2025British Journal of Anaesthesia3 citations Open access
Semantic Scholar

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