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S. Checquolo · SciRah

Researcher profile · Semantic Scholar

S. Checquolo

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S. Checquolo — researcher profile on SciRah

h-index: 27
Works: 50
Citations: 2,050

Most-cited papers

Heterozygous germline mutations in the CBL tumor-suppressor gene cause a Noonan syndrome-like phenotype.
S. Martinelli, A. De Luca, E. Stellacci, C. Rossi +22 more
2010American Journal of Human Genetics247 citations Open access
Semantic Scholar
Combined expression of pTα and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis
D. Bellavia, A. Campese, S. Checquolo, Anna Balestri +9 more
2002Proceedings of the National Academy of Sciences of the United States of America202 citations Open access
Semantic Scholar
Notch Signaling Activation as a Hallmark for Triple-Negative Breast Cancer Subtype
M. V. Giuli, E. Giuliani, I. Screpanti, D. Bellavia +1 more
2019Journal of Oncology155 citations Open access
Semantic Scholar
Expression of Activated Notch3 in Transgenic Mice Enhances Generation of T Regulatory Cells and Protects against Experimental Autoimmune Diabetes1
E. Anastasi, A. Campese, D. Bellavia, A. Bulotta +9 more
2003Journal of Immunology140 citations Open access
Semantic Scholar
Wnt, Notch, and TGF-β Pathways Impinge on Hedgehog Signaling Complexity: An Open Window on Cancer
M. Pelullo, Sabrina Zema, F. Nardozza, S. Checquolo +2 more
2019Frontiers in Genetics129 citations Open access
Semantic Scholar
Notch3: from subtle structural differences to functional diversity
D. Bellavia, S. Checquolo, A. Campese, M. Felli +2 more
2008Oncogene96 citations
Semantic Scholar
Pre‐TCR‐triggered ERK signalling‐dependent downregulation of E2A activity in Notch3‐induced T‐cell lymphoma
C. Talora, A. Campese, D. Bellavia, M. Pascucci +6 more
2003EMBO Reports79 citations Open access
Semantic Scholar
PKCθ mediates pre-TCR signaling and contributes to Notch3-induced T-cell leukemia
M. Felli, A. Vacca, Angelica Calce, D. Bellavia +10 more
2005Oncogene74 citations
Semantic Scholar
Current Trends in ATRA Delivery for Cancer Therapy
M. V. Giuli, P. Hanieh, E. Giuliani, F. Rinaldi +4 more
2020Pharmaceutics71 citations Open access
Semantic Scholar
Acetylation controls Notch3 stability and function in T-cell leukemia
R. Palermo, S. Checquolo, A. Giovenco, P. Grazioli +12 more
2012Oncogene63 citations Open access
Semantic Scholar
Opsonin-Deficient Nucleoproteic Corona Endows UnPEGylated Liposomes with Stealth Properties In Vivo
Francesca Giulimondi, E. Vulpis, L. Digiacomo, M. V. Giuli +15 more
2022ACS Nano62 citations Open access
Semantic Scholar
Notch3/Jagged1 Circuitry Reinforces Notch Signaling and Sustains T-ALL
M. Pelullo, R. Quaranta, C. Talora, S. Checquolo +11 more
2014Neoplasia52 citations Open access
Semantic Scholar
Structuring lipid nanoparticles, DNA, and protein corona into stealth bionanoarchitectures for in vivo gene delivery
Serena Renzi, L. Digiacomo, D. Pozzi, Erica Quagliarini +23 more
2024Nature Communications46 citations Open access
Semantic Scholar
Combined expression of pTalpha and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis.
D. Bellavia, A. Campese, S. Checquolo, Anna Balestri +9 more
2002Proceedings of the National Academy of Sciences of the United States of America46 citations
Semantic Scholar
Notch signaling as a therapeutic target for acute lymphoblastic leukemia
D. Bellavia, R. Palermo, M. Felli, I. Screpanti +1 more
2018Expert opinion on therapeutic targets45 citations
Semantic Scholar
PKC theta mediates pre-TCR signaling and contributes to Notch3-induced T-cell leukemia.
M. Felli, A. Vacca, Angelica Calce, D. Bellavia +10 more
2005Oncogene45 citations
Semantic Scholar
NOTCH3 inactivation increases triple negative breast cancer sensitivity to gefitinib by promoting EGFR tyrosine dephosphorylation and its intracellular arrest
G. Diluvio, F. Del Gaudio, M. V. Giuli, G. Franciosa +11 more
2018Oncogenesis44 citations Open access
Semantic Scholar
Maml1 acts cooperatively with Gli proteins to regulate sonic hedgehog signaling pathway
R. Quaranta, M. Pelullo, Sabrina Zema, F. Nardozza +10 more
2017Cell Death and Disease40 citations Open access
Semantic Scholar
The molecular basis of notch signaling regulation: a complex simplicity.
R. Palermo, S. Checquolo, D. Bellavia, C. Talora +1 more
2014Current molecular medicine37 citations
Semantic Scholar
Histone Modifications Drive Aberrant Notch3 Expression/Activity and Growth in T-ALL
Luca Tottone, Nadezda Zhdanovskaya, Álvaro Carmona Pestaña, Michele Zampieri +11 more
2019Frontiers in Oncology35 citations Open access
Semantic Scholar
Loss of Notch1-dependent p21Waf1/Cip1 expression influences the Notch1 outcome in tumorigenesis
Samantha Cialfi, R. Palermo, Sonia Manca, C. De Blasio +10 more
2014Cell Cycle34 citations Open access
Semantic Scholar
Kras/ADAM17-dependent Jag1-ICD reverse signalling sustains colorectal cancer progression and chemoresistance.
M. Pelullo, F. Nardozza, Sabrina Zema, R. Quaranta +13 more
2019Cancer Research32 citations Open access
Semantic Scholar
Mitogen-activated kinase kinase kinase 1 inhibits hedgehog signaling and medulloblastoma growth through GLI1 phosphorylation
L. Antonucci, L. Di Magno, D. D’Amico, S. Manni +17 more
2018International Journal of Oncology30 citations Open access
Semantic Scholar
Notch3 and pTalpha/pre-TCR sustain the in vivo function of naturally occurring regulatory T cells.
A. Campese, P. Grazioli, Sara Colantoni, E. Anastasi +7 more
2009International Immunology30 citations
Semantic Scholar
Notch3 Targeting: A Novel Weapon against Ovarian Cancer Stem Cells
S. Ceccarelli, F. Megiorni, D. Bellavia, C. Marchese +2 more
2019Stem Cells International29 citations Open access
Semantic Scholar
RET mutation and increased angiogenesis in medullary thyroid carcinomas.
A. Verrienti, G. Tallini, C. Colato, A. Boichard +13 more
2016Endocrine-Related Cancer28 citations Open access
Semantic Scholar
Differential subcellular localization regulates c-Cbl E3 ligase activity upon Notch3 protein in T-cell leukemia
S. Checquolo, R. Palermo, Samantha Cialfi, G. Ferrara +8 more
2010Oncogene28 citations
Semantic Scholar
Notch signaling in female cancers: a multifaceted node to overcome drug resistance
M. V. Giuli, Angelica Mancusi, E. Giuliani, I. Screpanti +1 more
2021Cancer Drug Resistance24 citations Open access
Semantic Scholar
Notch3 contributes to T-cell leukemia growth via regulation of the unfolded protein response
M. V. Giuli, G. Diluvio, E. Giuliani, G. Franciosa +14 more
2020Oncogenesis19 citations Open access
Semantic Scholar
PLK1 targets NOTCH1 during DNA damage and mitotic progression
C. De Blasio, Azzurra Zonfrilli, Matteo Franchitto, G. Mariano +8 more
2019Journal of Biological Chemistry17 citations Open access
Semantic Scholar
Human duodenal submucosal glands contain a defined stem/progenitor subpopulation with liver-specific regenerative potential.
V. Cardinale, G. Carpino, Diletta Overi, S. Safarikia +23 more
2022Journal of Hepatology13 citations Open access
Semantic Scholar
Identification of a Novel Curcumin Derivative Influencing Notch Pathway and DNA Damage as a Potential Therapeutic Agent in T-ALL
Nadezda Zhdanovskaya, Sara Lazzari, Diego Caprioglio, M. Firrincieli +10 more
2022Cancers10 citations Open access
Semantic Scholar
The Notch3 Receptor and Its Intracellular Signaling-Dependent Oncogenic Mechanisms.
D. Bellavia, S. Checquolo, R. Palermo, I. Screpanti
2018Advances in Experimental Medicine and Biology10 citations
Semantic Scholar
pH-sensitive niosoμes for ATRA delivery: a promising approach to inhibit Pin1 in High-grade Serous Ovarian Cancer.
Maria Valeria Giuli, Patrizia Nadia Hanieh, Jacopo Forte, Maria Gioia Fabiano +8 more
2023International journal of pharmaceutics9 citations Open access
Semantic Scholar
5FU/Oxaliplatin-Induced Jagged1 Cleavage Counteracts Apoptosis Induction in Colorectal Cancer: A Novel Mechanism of Intrinsic Drug Resistance
M. Pelullo, Sabrina Zema, Mariangela De Carolis, Samantha Cialfi +7 more
2022Frontiers in Oncology9 citations Open access
Semantic Scholar
Dilated cardiomyopathy due to a novel combination of TTN and BAG3 genetic variants: from acute heart failure to subclinical phenotypes.
B. Irene, G. Carla, Ciccone Maria Pia, Pignataro Maria Gemma +12 more
2024Cardiovascular pathology7 citations Open access
Semantic Scholar
Loss of CBL E3‐ligase activity in B‐lineage childhood acute lymphoblastic leukaemia
S. Martinelli, S. Checquolo, F. Consoli, E. Stellacci +11 more
2012British Journal of Haematology7 citations Open access
Semantic Scholar
MAML1 drives Notch and Hedgehog oncogenic pathways by inhibiting Itch activity in triple-negative breast cancer
Sabrina Zema, Francesca Di Fazio, M. Pelullo, Sara Di Savino +20 more
2025Cell Death and Differentiation3 citations Open access
Semantic Scholar
Prolyl-isomerase Pin1 drives platinum resistance by regulating Notch3 stability and function in ovarian cancer
M. V. Giuli, Angelica Mancusi, Bianca Natiello, S. Di Cristofano +26 more
2026Journal of experimental & clinical cancer research : CR2 citations Open access
Semantic Scholar
Loss of ATP2C1 function promotes trafficking and degradation of NOTCH1: Implications for Hailey‐Hailey disease
Azzurra Zonfrilli, Federica Truglio, A. Simeone, M. Pelullo +9 more
2023Experimental Dermatology2 citations Open access
Semantic Scholar
Correlation Between Oxidative Stress and Immune Profiles During Immunotherapy in Metastatic Non-Oncogene-Addicted NSCLC Patients
M. Peruzzi, Lucrezia Tuosto, A. Gelibter, C. Nocella +11 more
2026Antioxidants1 citations Open access
Semantic Scholar
pH-sensitive niosomal ATRA delivery as a promising approach to inhibit Pin1 in High-Grade Serous Ovarian Cancer
Maria Gioia Fabiano, Maria Valeria Giuli, Patrizia Nadia Hanieh, Jacopo Forte +4 more
2023Macedonian Pharmaceutical Bulletin0 citations Open access
Semantic Scholar
Notch3–EGFR crosstalk in triple negative breast cancers (TNBC): new therapeutic possibilities
G. Diluvio, F. Del Gaudio, G. Franciosa, M. V. Giuli +4 more
20160 citations
Semantic Scholar
Notch3 sustains CXCR4 expression in acute T cell lymphoblastic leukemia progression
F. Ferrandino, G. Bernardini, P. Grazioli, A. Campese +4 more
20160 citations
Semantic Scholar
The prolyl-isomerase Pin1 regulates Notch3 receptor maturation by influencing its migration to the cell membrane
S. Checquolo, D. Bellavia, I. Screpanti, C. Talora +5 more
20130 citations
Semantic Scholar
The prolyl-isomerase Pin1 regulates Notch3 receptor maturation process by influencing membrane migration of its transmembrane form
S. Checquolo, G. Franciosa, F. Del Gaudio, G. Diluvio +5 more
20130 citations
Semantic Scholar
The Prolyl-Isomerase PIN1 represent a regulator of Notch3 activity
S. Checquolo, D. Bellavia, I. Screpanti, A. Gulino +3 more
20110 citations
Semantic Scholar
Deletion of NF-kappaB/p50 influences the outcome of NOTCH3-dependent T cell leukemia
S. Checquolo, A. Campese, P. Grazioli, I. Screpanti +5 more
20110 citations
Semantic Scholar
This information is current as Autoimmune Diabetes Cells and Protects against Experimental Mice Enhances Generation of T Regulatory Expression of Activated Notch 3 in Transgenic
E. Anastasi, A. Campese, D. Bellavia, A. Bulotta +9 more
20030 citations
Semantic Scholar
Notch3 transgenic mice are protected against experimental autoimmune diabetes and display enhanced generation of T regulatory cells
E. Anastasi, A. Campese, D. Bellavia, A. Bulotta +9 more
20020 citations
Semantic Scholar

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