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S. Safarikia · SciRah

Researcher profile · Semantic Scholar

S. Safarikia

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S. Safarikia — researcher profile on SciRah

h-index: 11
Works: 32
Citations: 764

Most-cited papers

Increased Liver Localization of Lipopolysaccharides in Human and Experimental NAFLD
G. Carpino, M. del Ben, D. Pastori, R. Carnevale +12 more
2019Hepatology338 citations
Semantic Scholar
New insights into cholangiocarcinoma: multiple stems and related cell lineages of origin
M. Bragazzi, L. Ridola, S. Safarikia, S. Di Matteo +3 more
2017Annals of gastroenterology : quarterly publication of the Hellenic Society of Gastroenterology83 citations Open access
Semantic Scholar
Organoids and Spheroids as Models for Studying Cholestatic Liver Injury and Cholangiocarcinoma
Keisaku Sato, Wenjun Zhang, S. Safarikia, A. Isidan +9 more
2020Hepatology69 citations Open access
Semantic Scholar
The FXR agonist obeticholic acid inhibits the cancerogenic potential of human cholangiocarcinoma
S. Di Matteo, L. Nevi, D. Costantini, Diletta Overi +16 more
2019PLoS ONE54 citations Open access
Semantic Scholar
Peribiliary Gland Niche Participates in Biliary Tree Regeneration in Mouse and in Human Primary Sclerosing Cholangitis
G. Carpino, L. Nevi, Diletta Overi, V. Cardinale +10 more
2020Hepatology47 citations Open access
Semantic Scholar
Contribution of Resident Stem Cells to Liver and Biliary Tree Regeneration in Human Diseases
Diletta Overi, G. Carpino, V. Cardinale, A. Franchitto +4 more
2018International Journal of Molecular Sciences46 citations Open access
Semantic Scholar
Functions and the Emerging Role of the Foetal Liver into Regenerative Medicine
A. Giancotti, M. Monti, L. Nevi, S. Safarikia +11 more
2019Cells41 citations Open access
Semantic Scholar
Simulated microgravity promotes the formation of tridimensional cultures and stimulates pluripotency and a glycolytic metabolism in human hepatic and biliary tree stem/progenitor cells
D. Costantini, Diletta Overi, Luca Casadei, V. Cardinale +11 more
2019Scientific Reports39 citations Open access
Semantic Scholar
Human duodenal submucosal glands contain a defined stem/progenitor subpopulation with liver-specific regenerative potential.
V. Cardinale, G. Carpino, Diletta Overi, S. Safarikia +23 more
2022Journal of Hepatology13 citations Open access
Semantic Scholar
Distinct EpCAM-Positive Stem Cell Niches Are Engaged in Chronic and Neoplastic Liver Diseases
S. Safarikia, G. Carpino, Diletta Overi, V. Cardinale +5 more
2020Frontiers in Medicine12 citations Open access
Semantic Scholar
Cholest-4,6-Dien-3-One Promote Epithelial-To-Mesenchymal Transition (EMT) in Biliary Tree Stem/Progenitor Cell Cultures In Vitro
L. Nevi, D. Costantini, S. Safarikia, S. Di Matteo +3 more
2019Cells11 citations Open access
Semantic Scholar
Hyaluronan-Based Grafting Strategies for Liver Stem Cell Therapy and Tracking Methods
L. Nevi, S. Safarikia, S. Di Matteo, Francesca Biancaniello +2 more
2019Stem Cells International11 citations Open access
Semantic Scholar
OC.01.1 BILIARY TREE STEM CELLS PLAY A KEY ROLE IN THE REGENERATION OF BILIARY EPITHELIUM AFTER INJURY
L. Nevi, G. Carpino, V. Cardinale, Wei-Yu Lu +9 more
2019Digestive and Liver Disease0 citations
Semantic Scholar
PS-123-Biliary tree stem/progenitor cells mediate the regeneration in biliary lining after injury
L. Nevi, V. Cardinale, Wei-Yu Lu, S. Di Matteo +7 more
2019Journal of Hepatology0 citations
Semantic Scholar
Human duodenal submucosal glands contain stem cells with potential for liver and pancreatic regenerative medicine
G. Carpino, V. Cardinale, S. Safarikia, Diletta Overi +15 more
2019Digestive and Liver Disease0 citations
Semantic Scholar
THU-457-DoubleCortin/Like Kinase 1 (DCLK1) expression characterized specific cancer stem cell subpopulations of human cholangiocarcinoma primary cell cultures where its inhibition exerts anti-neoplastic effects
S. Di Matteo, L. Nevi, V. Cardinale, llaria Grazia Zizzari +14 more
2019Journal of Hepatology0 citations
Semantic Scholar
PC.01.6 HUMAN DUODENAL SUBMUCOSAL GLANDS CONTAIN STEM CELLS WITH POTENTIAL FOR LIVER AND PANCREATIC FATES
V. Cardinale, G. Carpino, S. Safarikia, Diletta Overi +15 more
2019Digestive and Liver Disease0 citations
Semantic Scholar
P.04.6 PRIMARY HUMAN BILIARY TREE STEM/PROGENITOR CELLS (HBTSCS) EXPOSED TO MICROENVIRONMENTAL FACTORS SHOWED PROLIFERATION, EPITHELIAL-MESENCHYMAL TRANSITION (EMT) AND SENESCENCE, RECAPITULATING THE PATHOLOGICAL FEATURES TYPICAL OF HUMAN CHOLANGIOPATHIES
D. Costantini, V. Cardinale, G. Carpino, L. Nevi +6 more
20180 citations
Semantic Scholar
OC.04.1 GENERATION OF 3D ORGANOIDS OF HUMAN FETAL BILIARY TREE STEM CELLS (HBTSCS) AS INNOVATIVE TOOL FOR THE REGENERATIVE MEDICINE OF LIVER AND PANCREAS
S. Safarikia, V. Cardinale, D. Costantini, S. Di Matteo +4 more
20180 citations
Semantic Scholar
Specific human cholangiocarcinoma (CCA) subpopulations of cancer stem cells (CSCs) express DoubleCortin-Like Kinase 1 (DCLK1) and DCLK1 inhibition induces anti-cancer effects
L. Nevi, S. Di Matteo, G. Carpino, V. Cardinale +13 more
20180 citations
Semantic Scholar
Different micro-environtmental factors induce proliferation, epithelial-mesenchymal transition (EMT) and senescence of primary cultures of human biliary tree stem/progenitor cells (hBTSCs), recapitulating the pathological features typical of human cholangiopathies
D. Costantini, G. Carpino, V. Cardinale, Diletta Overi +7 more
20180 citations
Semantic Scholar
Obeticholic acid, a FXR agonist, inhibits the cancerogenic potential of primary human cholangiocarcinoma (CCA) cells cultures
S. Di Matteo, L. Nevi, D. Constantini, M. Colantonio +13 more
20180 citations Open access
Semantic Scholar
OC.08.2 THE FXR AGONIST, OBETICHOLIC ACID, INHIBITS THE CANCEROGENIC POTENTIAL OF PRIMARY HUMAN CHOLANGIOCARCINOMA CELLS: A STUDY ON PRIMARY HUMAN CELL CULTURES
S. Di Matteo, L. Nevi, D. Costantini, M. Colantonio +14 more
20180 citations
Semantic Scholar
Establishment of expanding 3D-organoids cultures from human fetal biliary tree stem cells (hBTSCs) as a potential tool for regenerative medicine and disease modeling
S. Safarikia, V. Cardinale, G. Carpino, D. Costantini +5 more
20180 citations
Semantic Scholar
OC.08.1 DOUBLECORTIN-LIKE KINASE 1 (DCLK1) IS A MARKER OF SPECIFIC SUBPOPULATIONS OF CANCER STEM CELLS (CSCS) IN HUMAN CHOLANGIOCARCINOMA (CCA) AND ITS INHIBITION EXERTS ANTI-CANCER EFFECTS
L. Nevi, S. Di Matteo, G. Carpino, V. Cardinale +12 more
20180 citations
Semantic Scholar
Development of self-renewing 3D organoid culture from human fetal biliary tree stem cells (hBTSCs) as a potential system for regenerative medicine and disease modelling
S. Safarikia, V. Cardinale, G. Carpino, D. Costantini +5 more
20180 citations
Semantic Scholar
The cancerogenic potential of primary human Cholangioracinoma cells is inhibited by Obeticholic Acid, a Farnesoid X Receptor (FXR) agonist
S. Di Matteo, L. Nevi, D. Costantini, M. Colantonio +14 more
20180 citations
Semantic Scholar
The exposure of primary cultures of human biliary tree stem/progenitor cells (hBTSCs) to different micro-environmental factors induces proliferation, epithelial-mesenchymal transition (EMT) and senescence, which are typical pathological features of human cholangiopathies
D. Costantini, V. Cardinale, G. Carpino, L. Nevi +6 more
20180 citations
Semantic Scholar
Simulated microgravity significantly impacts the differentiation and metabolism of human hepatic and biliary tree stem/progenitor cells
D. Costantini, V. Cardinale, Luca Casadei, G. Carpino +8 more
20170 citations
Semantic Scholar
A new strategy to improve the liver engraftment efficiency of transplanted human biliary tree stem/progenitor cells: cell coating with hyaluronic acid
L. Nevi, G. Carpino, V. Cardinale, D. Costantini +7 more
20170 citations
Semantic Scholar
P.10.2: Hyaluronic Acid Improves the Engraftment Efficiency of Human Biliary Tree Stem/Progenitor Cells (HBTSCS)
L. Nevi, V. Cardinale, G. Carpino, D. Costantini +7 more
20170 citations
Semantic Scholar
Microgravity maintains stemness and enhance glycolytic metabolism in human hepatic and biliary tree stem/progenitor cells
D. Costantini, V. Cardinale, Luca Casadei, G. Carpino +8 more
20170 citations
Semantic Scholar

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