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Filip Cuyckens · SciRah

Researcher profile · Semantic Scholar

Filip Cuyckens

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Filip Cuyckens — researcher profile on SciRah

h-index: 31
Works: 96
Citations: 4,146

Most-cited papers

Mass spectrometry in the structural analysis of flavonoids.
Filip Cuyckens, M. Claeys
2004Journal of Mass Spectrometry1,088 citations
Semantic Scholar
Characterization of organosulfates from the photooxidation of isoprene and unsaturated fatty acids in ambient aerosol using liquid chromatography/(-) electrospray ionization mass spectrometry.
Y. Gómez-González, J. Surratt, Filip Cuyckens, R. Szmigielski +10 more
2008Journal of Mass Spectrometry224 citations
Semantic Scholar
A tutorial in small molecule identification via electrospray ionization‐mass spectrometry: The practical art of structural elucidation
Thomas de Vijlder, D. Valkenborg, F. Lemière, E. P. Romijn +2 more
2017Mass spectrometry reviews (Print)202 citations Open access
Semantic Scholar
Determination of the glycosylation site in flavonoid mono-O-glycosides by collision-induced dissociation of electrospray-generated deprotonated and sodiated molecules.
Filip Cuyckens, M. Claeys
2005Journal of Mass Spectrometry146 citations
Semantic Scholar
Absorption, Metabolism, and Excretion of Oral 14C Radiolabeled Ibrutinib: An Open-Label, Phase I, Single-Dose Study in Healthy Men
E. Scheers, L. Leclercq, J. D. de Jong, Nini Bode +7 more
2015Drug Metabolism And Disposition133 citations
Semantic Scholar
Which human metabolites have we MIST? Retrospective analysis, practical aspects, and perspectives for metabolite identification and quantification in pharmaceutical development.
L. Leclercq, Filip Cuyckens, G. Mannens, Ronald de Vries +2 more
2009Chemical Research in Toxicology122 citations
Semantic Scholar
Tandem mass spectral strategies for the structural characterization of flavonoid glycosides
Filip Cuyckens, Y.-L. Ma, G. Pocsfalvi, M. Claeys
2000115 citations Open access
Semantic Scholar
Mass spectrometric methods for the characterisation and differentiation of isomeric O-diglycosyl flavonoids.
Yu-Liang Ma, Filip Cuyckens, H. van den Heuvel, Magda Claeys
2001Phytochemical Analysis104 citations
Semantic Scholar
Herbal remedy-associated acute renal failure secondary to Cape aloes.
Valerie A Luyckx, R. Ballantine, M. Claeys, Filip Cuyckens +5 more
2002American Journal of Kidney Diseases95 citations
Semantic Scholar
Comparison of triple quadrupole and high-resolution TOF-MS for quantification of peptides.
L. Dillen, Willy Cools, L. Vereyken, W. Lorreyne +4 more
2012Bioanalysis87 citations
Semantic Scholar
Optimization of a liquid chromatography method based on simultaneous electrospray ionization mass spectrometric and ultraviolet photodiode array detection for analysis of flavonoid glycosides.
Filip Cuyckens, M. Claeys
2002Rapid Communications in Mass Spectrometry78 citations
Semantic Scholar
Absorption, Metabolism, and Excretion of Darunavir, a New Protease Inhibitor, Administered Alone and with Low-Dose Ritonavir in Healthy Subjects
M. Vermeir, S. Lachau-Durand, G. Mannens, Filip Cuyckens +2 more
2009Drug Metabolism And Disposition77 citations
Semantic Scholar
Infrared ion spectroscopy: New opportunities for small-molecule identification in mass spectrometry - A tutorial perspective.
J. Martens, Rianne E. van Outersterp, R. Vreeken, Filip Cuyckens +8 more
2020Analytica Chimica Acta73 citations Open access
Semantic Scholar
High-resolution laser ablation-inductively coupled plasma-mass spectrometry imaging of cisplatin-induced nephrotoxic side effects.
T. Van Acker, S. V. Van Malderen, M. van Heerden, J. McDuffie +2 more
2016Analytica Chimica Acta69 citations Open access
Semantic Scholar
Use of the bromine isotope ratio in HPLC-ICP-MS and HPLC-ESI-MS analysis of a new drug in development
Filip Cuyckens, L. Balcaen, K. De Wolf, B. De Samber +3 more
2008Analytical and Bioanalytical Chemistry64 citations
Semantic Scholar
Combined Liquid Chromatography-Infrared Ion Spectroscopy for Identification of Regioisomeric Drug Metabolites
J. Martens, Valérie Koppen, G. Berden, Filip Cuyckens +1 more
2017Analytical Chemistry61 citations Open access
Semantic Scholar
Metabolism and Excretion of Canagliflozin in Mice, Rats, Dogs, and Humans
R. Mamidi, Filip Cuyckens, Jie Chen, E. Scheers +9 more
2014Drug Metabolism And Disposition61 citations Open access
Semantic Scholar
Product ion mobility as a promising tool for assignment of positional isomers of drug metabolites.
Filip Cuyckens, C. Wassvik, R. Mortishire-Smith, G. Tresadern +2 more
2011Rapid Communications in Mass Spectrometry56 citations
Semantic Scholar
Extracting metabolite ions out of a matrix background by combined mass defect, neutral loss and isotope filtration.
Filip Cuyckens, R. Hurkmans, J. Castro-Pérez, L. Leclercq +1 more
2009Rapid Communications in Mass Spectrometry50 citations
Semantic Scholar
Direct stereochemical assignment of hexose and pentose residues in flavonoid O-glycosides by fast atom bombardment and electrospray ionization mass spectrometry.
Filip Cuyckens, A. Shahat, L. Pieters, M. Claeys
2002Journal of Mass Spectrometry46 citations
Semantic Scholar
Disposition, Metabolism, and Excretion of [14C]Doripenem after a Single 500-Milligram Intravenous Infusion in Healthy Men
I. Cirillo, G. Mannens, C. Janssen, M. Vermeir +7 more
2008Antimicrobial Agents and Chemotherapy42 citations Open access
Semantic Scholar
Speciation analysis of bromine-containing drug metabolites in feces samples from a human in vivo study by means of HPLC/ICP-MS combined with on-line isotope dilution
Björn Meermann, M. Bockx, A. Laenen, Cis Van Looveren +2 more
2011Analytical and Bioanalytical Chemistry40 citations
Semantic Scholar
Apalutamide Absorption, Metabolism, and Excretion in Healthy Men, and Enzyme Reaction in Human Hepatocytes
Ronald de Vries, F. Jacobs, G. Mannens, J. Snoeys +3 more
2019Drug Metabolism And Disposition38 citations Open access
Semantic Scholar
Physiologically Based Pharmacokinetic Predictions of Tramadol Exposure Throughout Pediatric Life: an Analysis of the Different Clearance Contributors with Emphasis on CYP2D6 Maturation
Huybrecht T'jollyn, J. Snoeys, A. Vermeulen, R. Michelet +7 more
2015AAPS Journal37 citations Open access
Semantic Scholar
Mass spectrometry in drug metabolism and pharmacokinetics: Current trends and future perspectives.
Filip Cuyckens
2018Rapid Communications in Mass Spectrometry36 citations Open access
Semantic Scholar
Structural characterization of flavonol di-O-glycosides from Farsetia aegyptia by electrospray ionization and collision-induced dissociation mass spectrometry.
A. Shahat, Filip Cuyckens, Wu Wang, K. A. Abdel-Shafeek +6 more
2005Rapid Communications in Mass Spectrometry36 citations
Semantic Scholar
Mass Spectrometry Imaging of Drug Related Crystal-Like Structures in Formalin-Fixed Frozen and Paraffin-Embedded Rabbit Kidney Tissue Sections
A. L. Bruinen, Cateau van Oevelen, Gert B. Eijkel, M. van Heerden +2 more
2015Journal of the American Society for Mass Spectrometry35 citations Open access
Semantic Scholar
Improved liquid chromatography-Online radioactivity detection for metabolite profiling.
Filip Cuyckens, Valérie Koppen, Rainer Kembuegler, L. Leclercq
2008Journal of Chromatography A33 citations
Semantic Scholar
Fast high-performance liquid chromatography method for quality control of soy extracts.
S. Apers, T. Naessens, Katleen van den Steen, Filip Cuyckens +3 more
2004Journal of Chromatography A33 citations
Semantic Scholar
Determination of the total drug-related chlorine and bromine contents in human blood plasma using high performance liquid chromatography-tandem ICP-mass spectrometry (HPLC-ICP-MS/MS).
Balázs Klencsár, E. Bolea-Fernandez, María R. Flórez, L. Balcaen +3 more
2016Journal of Pharmaceutical and Biomedical Analysis32 citations
Semantic Scholar
Novel, broad-spectrum anticonvulsants containing a sulfamide group: advancement of N-((benzo[b]thien-3-yl)methyl)sulfamide (JNJ-26990990) into human clinical studies.
M. H. Parker, Virginia L. Smith-Swintosky, David F. McComsey, Yifang Huang +15 more
2009Journal of Medicinal Chemistry32 citations Open access
Semantic Scholar
Hyphenation of reverse-phase HPLC and ICP-MS for metabolite profiling—application to a novel antituberculosis compound as a case study
L. Balcaen, B. De Samber, K. De Wolf, Filip Cuyckens +1 more
2007Analytical and Bioanalytical Chemistry30 citations
Semantic Scholar
Cross-Species Molecular Imaging of Bile Salts and Lipids in Liver: Identification of Molecular Structural Markers in Health and Disease
B. Flinders, Lennart R. S. Huizing, M. van Heerden, Filip Cuyckens +6 more
2018Analytical Chemistry29 citations Open access
Semantic Scholar
Enhanced performance for the analysis of prostaglandins and thromboxanes by liquid chromatography-tandem mass spectrometry using a new atmospheric pressure ionization source.
Arnaud Lubin, Suzy Geerinckx, S. Bajic, Deirdre Cabooter +3 more
2016Journal of Chromatography A29 citations Open access
Semantic Scholar
IsoScore: automated localization of biotransformations by mass spectrometry using product ion scoring of virtual regioisomers.
L. Leclercq, R. Mortishire-Smith, M. T. Huisman, Filip Cuyckens +2 more
2009Rapid Communications in Mass Spectrometry28 citations
Semantic Scholar
The Application of Liquid Chromatography-Electrospray Ionization Mass Spectrometry and Collision-Induced Dissociation in the Structural Characterization of Acylated Flavonol O-Glycosides from the Seeds of Carrichtera Annua
Filip Cuyckens, A. Shahat, H. van den Heuvel, K. A. Abdel-Shafeek +5 more
2003European Journal of Mass Spectrometry28 citations
Semantic Scholar
A pilot study on the use of laser ablation-ICP-mass spectrometry for assessing/mapping the distribution of a drug and its metabolites across the body compartments of rats
A. Izmer, D. Gholap, Kathleen De Houwer, Filip Cuyckens +1 more
201227 citations
Semantic Scholar
A comparison between HPLC-dynamic reaction cell-ICP-MS and HPLC-sector field-ICP-MS for the detection of glutathione-trapped reactive drug metabolites using clozapine as a model compound
K. De Wolf, L. Balcaen, E. Van de Walle, Filip Cuyckens +1 more
201026 citations Open access
Semantic Scholar
Quantitative Mass Spectrometry Imaging to Study Drug Distribution in the Intestine Following Oral Dosing.
Lennart R. S. Huizing, J. McDuffie, Filip Cuyckens, M. van Heerden +3 more
2021Analytical Chemistry25 citations Open access
Semantic Scholar
In vitro and physiologically‐based pharmacokinetic based assessment of drug–drug interaction potential of canagliflozin
R. Mamidi, S. Dallas, C. Sensenhauser, H. Lim +8 more
2017British Journal of Clinical Pharmacology25 citations Open access
Semantic Scholar
Montmorillonite and Laponite Clay Materials for the Solidification of Lipid-Based Formulations for the Basic Drug Blonanserin: In Vitro and in Vivo Investigations.
Tahnee J. Dening, Nicky Thomas, Shasha Rao, Cis van Looveren +3 more
2018Molecular Pharmaceutics24 citations Open access
Semantic Scholar
Atmospheric Pressure Ionization Using a High Voltage Target Compared to Electrospray Ionization
Arnaud Lubin, S. Bajic, Deirdre Cabooter, P. Augustijns +1 more
2017Journal of the American Society for Mass Spectrometry24 citations Open access
Semantic Scholar
HPLC/ICP-MS in combination with "reverse" online isotope dilution in drug metabolism studies.
Björn Meermann, Anne Hulstaert, A. Laenen, Cis Van Looveren +3 more
2012Analytical Chemistry24 citations
Semantic Scholar
In vitro studies on the metabolism of trabectedin (YONDELIS) in monkey and man, including human CYP reaction phenotyping.
M. Vermeir, A. Hemeryck, Filip Cuyckens, A. Francesch +6 more
2009Biochemical Pharmacology24 citations Open access
Semantic Scholar
Considerations for Human ADME Strategy and Design Paradigm Shift(s) – An Industry White Paper
G. Young, D. Spracklin, A. James, Mette G. Hvenegaard +15 more
2022Clinical pharmacology and therapy23 citations Open access
Semantic Scholar
Development and validation of a novel quantification approach for gradient elution reversed phase high-performance liquid chromatography coupled to tandem ICP-mass spectrometry (RP-HPLC-ICP-MS/MS) and its application to diclofenac and its related compounds.
Balázs Klencsár, L. Balcaen, Filip Cuyckens, F. Lynen +1 more
2017Analytica Chimica Acta23 citations
Semantic Scholar
Identifying metabolite ions of peptide drugs in the presence of an in vivo matrix background.
Filip Cuyckens, L. Dillen, Willy Cools, M. Bockx +3 more
2012Bioanalysis23 citations
Semantic Scholar
Structural characterization of chromone C-glucosides in a toxic herbal remedy.
Wu Wang, Filip Cuyckens, H. van den Heuvel, S. Apers +5 more
2003Rapid Communications in Mass Spectrometry22 citations
Semantic Scholar
Physiology-Based IVIVE Predictions of Tramadol from in Vitro Metabolism Data
Huybrecht T'jollyn, J. Snoeys, P. Colin, J. Van Bocxlaer +7 more
2014Pharmaceutical Research21 citations Open access
Semantic Scholar
Characterization of metal complexes with metallothioneins in the liver of the carp Cyprinus carpio by reversed-phase HPLC with ICP-MS and electrospray ionization (ESI)-MS
H. G. Infante, Filip Cuyckens, K. van Campenhout, R. Blust +3 more
200421 citations
Semantic Scholar

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M. Claeys — researcher profile on SciRah
F. Vanhaecke×9
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