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R. Vreeken · SciRah

Researcher profile · Semantic Scholar

R. Vreeken

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R. Vreeken — researcher profile on SciRah

h-index: 50
Works: 145
Citations: 6,804

Most-cited papers

Increase in short-chain ceramides correlates with an altered lipid organization and decreased barrier function in atopic eczema patients[S]
M. Janssens, J. van Smeden, G. Gooris, W. Bras +8 more
2012Journal of Lipid Research431 citations Open access
Semantic Scholar
The importance of free fatty acid chain length for the skin barrier function in atopic eczema patients
J. van Smeden, M. Janssens, E. Kaye, P. Caspers +3 more
2014Experimental Dermatology256 citations Open access
Semantic Scholar
Quantitative profiling of oxylipins through comprehensive LC-MS/MS analysis: application in cardiac surgery
K. Strassburg, A. Huijbrechts, K. Kortekaas, J. Lindeman +9 more
2012Analytical and Bioanalytical Chemistry227 citations Open access
Semantic Scholar
Lipidomics of familial longevity
V. González-Covarrubias, M. Beekman, H. Uh, A. Dane +7 more
2013Aging Cell161 citations Open access
Semantic Scholar
Potent Peptidic Fusion Inhibitors of Influenza Virus
R. U. Kadam, J. Juraszek, Boerries Brandenburg, Christophe Buyck +12 more
2017Science150 citations Open access
Semantic Scholar
Altered expression of epidermal lipid bio-synthesis enzymes in atopic dermatitis skin is accompanied by changes in stratum corneum lipid composition.
M. Danso, Walter A. Boiten, V. van Drongelen, Kevin A. Gmelig Meijling +8 more
2017Journal of dermatological science (Amsterdam)125 citations Open access
Semantic Scholar
Recent developments in sample-pretreatment techniques for mass spectrometry-based metabolomics
R. Raterink, P. Lindenburg, R. Vreeken, R. Ramautar +1 more
2014123 citations
Semantic Scholar
Combined LC/MS-platform for analysis of all major stratum corneum lipids, and the profiling of skin substitutes.
J. van Smeden, Walter A. Boiten, T. Hankemeier, R. Rissmann +2 more
2014Biochimica et Biophysica Acta120 citations
Semantic Scholar
Enhanced Sensitivity Using MALDI Imaging Coupled with Laser Postionization (MALDI-2) for Pharmaceutical Research
Florian P. Y. Barré, Martin R. L. Paine, B. Flinders, A. Trevitt +9 more
2019Analytical Chemistry103 citations Open access
Semantic Scholar
Metabolite identification using automated comparison of high-resolution multistage mass spectral trees.
Miquel Rojas-Chertó, Julio E. Peironcely, P. Kasper, J. V. D. van der Hooft +4 more
2012Analytical Chemistry98 citations Open access
Semantic Scholar
Enhanced lipid isomer separation in human plasma using reversed-phase UPLC with ion-mobility/high-resolution MS detection[S]
C. Damen, G. Isaac, J. Langridge, T. Hankemeier +1 more
2014Journal of Lipid Research97 citations Open access
Semantic Scholar
A Branched Biosynthetic Pathway Is Involved in Production of Roquefortine and Related Compounds in Penicillium chrysogenum
H. Ali, Marco I. Ries, J. Nijland, P. P. Lankhorst +4 more
2013PLoS ONE92 citations Open access
Semantic Scholar
Intercellular skin barrier lipid composition and organization in Netherton syndrome patients.
J. van Smeden, M. Janssens, Walter A. Boiten, V. van Drongelen +4 more
2014Journal of Investigative Dermatology88 citations Open access
Semantic Scholar
Roux-en-Y Gastric Bypass Surgery, but Not Calorie Restriction, Reduces Plasma Branched-Chain Amino Acids in Obese Women Independent of Weight Loss or the Presence of Type 2 Diabetes
M. Lips, J. V. van Klinken, V. van Harmelen, Harish Dharuri +15 more
2014Diabetes Care87 citations Open access
Semantic Scholar
An efficient hydrophilic interaction liquid chromatography separation of 7 phospholipid classes based on a diol column.
Chaowei. Zhu, A. Dane, G. Spijksma, Mei Wang +4 more
2012Journal of Chromatography A82 citations
Semantic Scholar
Transient inflammatory-like state and microbial dysbiosis are pivotal in establishment of mucosal homeostasis during colonisation of germ-free mice.
S. El Aidy, M. Derrien, R. Aardema, G. Hooiveld +9 more
2014Beneficial Microbes78 citations Open access
Semantic Scholar
Metabolomics Profiling for Identification of Novel Potential Markers in Early Prediction of Preeclampsia
S. Kuć, M. P. Koster, J. Pennings, T. Hankemeier +6 more
2014PLoS ONE77 citations Open access
Semantic Scholar
The influence of citrate, EDTA, and heparin anticoagulants to human plasma LC–MS lipidomic profiling
V. González-Covarrubias, A. Dane, T. Hankemeier, R. Vreeken
2013Metabolomics76 citations
Semantic Scholar
Metabolic characterization of the natural progression of chronic hepatitis B
J. Schoeman, Jun-Liang Hou, A. Harms, R. Vreeken +3 more
2016Genome Medicine75 citations Open access
Semantic Scholar
Infrared ion spectroscopy: New opportunities for small-molecule identification in mass spectrometry - A tutorial perspective.
J. Martens, Rianne E. van Outersterp, R. Vreeken, Filip Cuyckens +8 more
2020Analytica Chimica Acta73 citations Open access
Semantic Scholar
Gender-Dependent Associations of Metabolite Profiles and Body Fat Distribution in a Healthy Population with Central Obesity: Towards Metabolomics Diagnostics
E. Szymańska, J. Bouwman, K. Strassburg, J. Vervoort +10 more
2012Omics70 citations Open access
Semantic Scholar
Metabolic Phenotyping Reveals a Lipid Mediator Response to Ionizing Radiation
E. Laiakis, K. Strassburg, R. Bogumil, S. Lai +6 more
2014Journal of Proteome Research69 citations Open access
Semantic Scholar
Increased presence of monounsaturated fatty acids in the stratum corneum of human skin equivalents.
Varsha S. Thakoersing, J. van Smeden, A. Mulder, R. Vreeken +2 more
2013Journal of Investigative Dermatology64 citations Open access
Semantic Scholar
Comprehensive metabolomics to evaluate the impact of industrial processing on the phytochemical composition of vegetable purees.
Patricia López-Sánchez, R. D. de Vos, H. Jonker, R. Mumm +8 more
2015Food Chemistry63 citations Open access
Semantic Scholar
Three-phase electroextraction: a new (online) sample purification and enrichment method for bioanalysis.
R. Raterink, P. Lindenburg, R. Vreeken, T. Hankemeier
2013Analytical Chemistry63 citations
Semantic Scholar
Identification of a Polyketide Synthase Involved in Sorbicillin Biosynthesis by Penicillium chrysogenum
Oleksandr V. Salo, Fernando Guzman-Chavez, Marco I. Ries, P. P. Lankhorst +3 more
2016Applied and Environmental Microbiology62 citations Open access
Semantic Scholar
Spatial heterogeneity of nanomedicine investigated by multiscale imaging of the drug, the nanoparticle and the tumour environment
Josanne S. de Maar, Alexandros Marios Sofias, Tiffany Porta Siegel, R. Vreeken +3 more
2020Theranostics59 citations Open access
Semantic Scholar
Genomic mutational analysis of the impact of the classical strain improvement program on β–lactam producing Penicillium chrysogenum
Oleksandr V. Salo, Marco I. Ries, M. Medema, P. P. Lankhorst +3 more
2015BMC Genomics59 citations Open access
Semantic Scholar
Testing Tuberculosis Drug Efficacy in a Zebrafish High-Throughput Translational Medicine Screen
A. Ordas, R. Raterink, F. Cunningham, H. Jansen +11 more
2014Antimicrobial Agents and Chemotherapy59 citations Open access
Semantic Scholar
First-Trimester Serum Acylcarnitine Levels to Predict Preeclampsia: A Metabolomics Approach
M. P. Koster, R. Vreeken, A. Harms, A. Dane +6 more
2015Disease Markers55 citations Open access
Semantic Scholar
A Non-Canonical NRPS Is Involved in the Synthesis of Fungisporin and Related Hydrophobic Cyclic Tetrapeptides in Penicillium chrysogenum
H. Ali, Marco I. Ries, P. P. Lankhorst, R. V. D. Van Der Hoeven +7 more
2014PLoS ONE54 citations Open access
Semantic Scholar
Development and evaluation of matrix application techniques for high throughput mass spectrometry imaging of tissues in the clinic.
Lennart R. S. Huizing, S. Ellis, B. Beulen, Florian P. Y. Barré +3 more
2019Clinical Mass Spectrometry53 citations Open access
Semantic Scholar
Automated pipeline for de novo metabolite identification using mass-spectrometry-based metabolomics.
Julio E. Peironcely, M. Rojas-Chertó, A. Tas, R. Vreeken +3 more
2013Analytical Chemistry52 citations Open access
Semantic Scholar
Fragmentation trees for the structural characterisation of metabolites
P. Kasper, M. Rojas-Chertó, R. Mistrik, T. Reijmers +2 more
2012Rapid Communications in Mass Spectrometry51 citations Open access
Semantic Scholar
Skin of atopic dermatitis patients shows disturbed β-glucocerebrosidase and acid sphingomyelinase activity that relates to changes in stratum corneum lipid composition.
Daphne E. C. Boer, J. van Smeden, Hanin Al-Khakany, E. Melnik +8 more
2020Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids50 citations Open access
Semantic Scholar
Novel Key Metabolites Reveal Further Branching of the Roquefortine/Meleagrin Biosynthetic Pathway*
Marco I. Ries, H. Ali, P. P. Lankhorst, T. Hankemeier +3 more
2013Journal of Biological Chemistry50 citations Open access
Semantic Scholar
Quantitative analysis of ceramides using a novel lipidomics approach with three dimensional response modelling.
Walter A. Boiten, Samira Absalah, R. Vreeken, J. Bouwstra +1 more
2016Biochimica et Biophysica Acta48 citations
Semantic Scholar
Endometriosis is associated with aberrant metabolite profiles in plasma.
Sophia Letsiou, D. Peterse, A. Fassbender, M. Hendriks +13 more
2017Fertility and Sterility47 citations Open access
Semantic Scholar
Postprandial fatty acid specific changes in circulating oxylipins in lean and obese men after high-fat challenge tests.
K. Strassburg, D. Esser, R. Vreeken, T. Hankemeier +6 more
2014Molecular Nutrition & Food Research45 citations Open access
Semantic Scholar
A lipidomic analysis approach to evaluate the response to cholesterol-lowering food intake
E. Szymańska, F. V. van Dorsten, Jorne Troost, Iryna Paliukhovich +6 more
2011Metabolomics45 citations Open access
Semantic Scholar
Targeted Drug and Metabolite Imaging: Desorption Electrospray Ionization Combined with Triple Quadrupole Mass Spectrometry
L. Lamont, Gert B. Eijkel, E. Jones, B. Flinders +4 more
2018Analytical Chemistry44 citations Open access
Semantic Scholar
Quantitative mass spectrometry imaging of drugs and metabolites: a multiplatform comparison
L. Lamont, D. Hadavi, Brent Viehmann, B. Flinders +3 more
2021Analytical and Bioanalytical Chemistry41 citations Open access
Semantic Scholar
Lesional skin of seborrheic dermatitis patients is characterized by skin barrier dysfunction and correlating alterations in the stratum corneum ceramide composition
J. Rousel, Andreea Nădăban, Mahdi Saghari, L. Pagan +11 more
2023Experimental Dermatology36 citations Open access
Semantic Scholar
A Protective Lipidomic Biosignature Associated with a Balanced Omega-6/Omega-3 Ratio in fat-1 Transgenic Mice
G. Astarita, J. H. McKenzie, Bin Wang, K. Strassburg +8 more
2014PLoS ONE36 citations Open access
Semantic Scholar
Analysis of oxysterols and vitamin D metabolites in mouse brain and cell line samples by ultra-high-performance liquid chromatography-atmospheric pressure photoionization-mass spectrometry.
Linda Ahonen, Florian Maire, Mari H. Savolainen, Jaakko Kopra +5 more
2014Journal of Chromatography A36 citations
Semantic Scholar
Integration of Ion Mobility MSE after Fully Automated, Online, High-Resolution Liquid Extraction Surface Analysis Micro-Liquid Chromatography
L. Lamont, Mark Baumert, Nina Ogrinc Potočnik, M. Allen +3 more
2017Analytical Chemistry35 citations Open access
Semantic Scholar
Development and application of a UHPLC–MS/MS metabolomics based comprehensive systemic and tissue-specific screening method for inflammatory, oxidative and nitrosative stress
J. Schoeman, A. Harms, M. van Weeghel, R. Berger +2 more
2018Analytical and Bioanalytical Chemistry33 citations Open access
Semantic Scholar
Fetal Metabolic Stress Disrupts Immune Homeostasis and Induces Proinflammatory Responses in Human Immunodeficiency Virus Type 1– and Combination Antiretroviral Therapy–Exposed Infants
J. Schoeman, G. P. Moutloatse, A. Harms, R. Vreeken +7 more
2017Journal of Infectious Diseases33 citations Open access
Semantic Scholar
Deregulation of secondary metabolism in a histone deacetylase mutant of Penicillium chrysogenum
Fernando Guzman-Chavez, Oleksandr V. Salo, M. Samol, Marco I. Ries +4 more
2018MicrobiologyOpen32 citations Open access
Semantic Scholar
Metabolomics profiling of the free and total oxidised lipids in urine by LC-MS/MS: application in patients with rheumatoid arthritis
Jun-Zeng Fu, J. Schoeman, A. Harms, H. V. van Wietmarschen +6 more
2016Analytical and Bioanalytical Chemistry32 citations Open access
Semantic Scholar

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