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D. Yapp · SciRah

Researcher profile · Semantic Scholar

D. Yapp

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D. Yapp — researcher profile on SciRah

h-index: 25
Works: 86
Citations: 1,767

Most-cited papers

Regulation of pH by Carbonic Anhydrase 9 Mediates Survival of Pancreatic Cancer Cells With Activated KRAS in Response to Hypoxia.
P. McDonald, S. Chafe, W. Brown, S. Saberi +16 more
2019Gastroenterology205 citations Open access
Semantic Scholar
Autophagy Inhibition Augments the Anticancer Effects of Epirubicin Treatment in Anthracycline-Sensitive and -Resistant Triple-Negative Breast Cancer
S. Chittaranjan, S. Bortnik, W. Dragowska, Jing Xu +9 more
2014Clinical Cancer Research146 citations Open access
Semantic Scholar
An organotrifluoroborate for broadly applicable one-step 18F-labeling.
Zhibo Liu, Maral Pourghiasian, M. Radtke, Joseph Lau +6 more
2014Angewandte Chemie143 citations
Semantic Scholar
Suppression of VEGF secretion and changes in glioblastoma multiforme microenvironment by inhibition of Integrin-linked kinase (ILK)
Lincoln A. Edwards, Janet Woo, L. Huxham, M. Verreault +14 more
2008Molecular Cancer Therapeutics69 citations Open access
Semantic Scholar
RGD conjugates of the H2dedpa scaffold: synthesis, labeling and imaging with 68Ga.
E. Boros, Cara L. Ferreira, D. Yapp, R. K. Gill +3 more
2012Nuclear Medicine and Biology68 citations
Semantic Scholar
Increasing the bioavailability of Ru(III) anticancer complexes through hydrophobic albumin interactions.
Michael I. Webb, Bo Wu, Thalia Jang, Ryan Chard +4 more
2013Chemistry62 citations
Semantic Scholar
Vascular normalization in orthotopic glioblastoma following intravenous treatment with lipid-based nanoparticulate formulations of irinotecan (Irinophore C™), doxorubicin (Caelyx®) or vincristine
M. Verreault, Dita Strutt, D. Masin, M. Anantha +5 more
2011BMC Cancer60 citations Open access
Semantic Scholar
Functional Imaging of Oxidative Stress with a Novel PET Imaging Agent, 18F-5-Fluoro-l-Aminosuberic Acid
Jack M. Webster, Christine A. Morton, B. F. Johnson, Hua Yang +6 more
2014Journal of Nuclear Medicine53 citations Open access
Semantic Scholar
Kit-like 18F-labeling of RGD-19F-arytrifluroborate in high yield and at extraordinarily high specific activity with preliminary in vivo tumor imaging.
Zhibo Liu, Ying Li, Jerome Lozada, M. Wong +4 more
2013Nuclear Medicine and Biology53 citations
Semantic Scholar
Evaluation of novel bifunctional chelates for the development of Cu-64-based radiopharmaceuticals.
Cara L. Ferreira, D. Yapp, Eric Lamsa, M. Gleave +3 more
2008Nuclear Medicine and Biology52 citations
Semantic Scholar
(68)Ga small peptide imaging: comparison of NOTA and PCTA.
Cara L. Ferreira, D. Yapp, Derek Mandel, R. K. Gill +4 more
2012Bioconjugate chemistry49 citations
Semantic Scholar
Irinophore C, a Novel Nanoformulation of Irinotecan, Alters Tumor Vascular Function and Enhances the Distribution of 5-Fluorouracil and Doxorubicin
J. Baker, Jeffrey Lam, Alaistair H Kyle, J. Sy +13 more
2008Clinical Cancer Research47 citations Open access
Semantic Scholar
Dual mode fluorescent (18)F-PET tracers: efficient modular synthesis of rhodamine-[cRGD]2-[(18)F]-organotrifluoroborate, rapid, and high yielding one-step (18)F-labeling at high specific activity, and correlated in vivo PET imaging and ex vivo fluorescence.
Zhibo Liu, M. Radtke, M. Wong, Kuo-Shyan Lin +2 more
2014Bioconjugate chemistry46 citations
Semantic Scholar
Comparison of bifunctional chelates for 64Cu antibody imaging
Cara L. Ferreira, D. Yapp, S. Crisp, Brent W. Sutherland +5 more
2010European Journal of Nuclear Medicine and Molecular Imaging46 citations
Semantic Scholar
Characterization of cationic liposome formulations designed to exhibit extended plasma residence times and tumor vasculature targeting properties.
E. Ho, E. Ramsay, M. Ginj, M. Anantha +6 more
2010Journal of Pharmacy and Science44 citations
Semantic Scholar
The Phosphoinositide-Dependent Kinase-1 Inhibitor 2-Amino-N-[4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-acetamide (OSU-03012) Prevents Y-Box Binding Protein-1 from Inducing Epidermal Growth Factor Receptor
Karen To, Yongjun Zhao, Helen Jiang, K. Hu +11 more
2007Molecular Pharmacology42 citations
Semantic Scholar
Induction of Cytotoxicity in Pyridine Analogues of the Anti-metastatic Ru(III) Complex NAMI-A by Ferrocene Functionalization.
Chang-Hua Mu, Stephanie W. Chang, Kathleen E. Prosser, A. Leung +8 more
2016Inorganic Chemistry36 citations Open access
Semantic Scholar
The differential effects of metronomic gemcitabine and antiangiogenic treatment in patient-derived xenografts of pancreatic cancer: treatment effects on metabolism, vascular function, cell proliferation, and tumor growth
D. Yapp, M. Wong, A. Kyle, Shannon M. Valdez +9 more
2016Angiogenesis36 citations Open access
Semantic Scholar
Single step 18F-labeling of dimeric cycloRGD for functional PET imaging of tumors in mice.
Ying Li, Zhibo Liu, Jerome Lozada, M. Wong +3 more
2013Nuclear Medicine and Biology30 citations
Semantic Scholar
Irinophore C™, a lipid-based nanoparticulate formulation of irinotecan, is more effective than free irinotecan when used to treat an orthotopic glioblastoma model.
M. Verreault, Dita Strutt, D. Masin, M. Anantha +3 more
2012Journal of Controlled Release29 citations
Semantic Scholar
Nitroimidazole-Containing H2dedpa and H2CHXdedpa Derivatives as Potential PET Imaging Agents of Hypoxia with (68)Ga.
C. Ramogida, Jinhe Pan, Cara L. Ferreira, B. Patrick +5 more
2015Inorganic Chemistry28 citations Open access
Semantic Scholar
HER-2/neu overexpression increases the viable hypoxic cell population within solid tumors without causing changes in tumor vascularization.
W. Dragowska, C. Warburton, D. Yapp, A. Minchinton +9 more
2004Molecular Cancer Research28 citations Open access
Semantic Scholar
Irinophore C™, a lipid nanoparticulate formulation of irinotecan, improves vascular function, increases the delivery of sequentially administered 5-FU in HT-29 tumors, and controls tumor growth in patient derived xenografts of colon cancer.
R. Neijzen, M. Wong, Navdeep Gill, He Wang +8 more
2015Journal of Controlled Release26 citations
Semantic Scholar
A new 18F-heteroaryltrifluoroborate radio-prosthetic with greatly enhanced stability that is labelled by 18F–19F-isotope exchange in good yield at high specific activity
Zhibo Liu, Navjit Hundal-Jabal, M. Wong, D. Yapp +3 more
201426 citations
Semantic Scholar
The involvement of insulin-like growth factor 2 binding protein 3 (IMP3) in pancreatic cancer cell migration, invasion, and adhesion
Clarissa C. Pasiliao, Che-Wei Chang, Brent W. Sutherland, Shannon M. Valdez +3 more
2015BMC Cancer25 citations Open access
Semantic Scholar
Using a Microfluidics System to Reproducibly Synthesize Protein Nanoparticles: Factors Contributing to Size, Homogeneity, and Stability
Courtney van Ballegooie, A. Man, I. Andreu, Byron D. Gates +1 more
2019Processes24 citations Open access
Semantic Scholar
Hypoxia in the Androgen-Dependent Shionogi Model for Prostate Cancer at Three Stages1
K. Skov, H. Adomat, M. Bowden, W. Dragowska +4 more
2004Radiation Research24 citations
Semantic Scholar
Spatially Specific Liposomal Cancer Therapy Triggered by Clinical External Sources of Energy
Courtney van Ballegooie, A. Man, Win Mi, D. Yapp
2019Pharmaceutics21 citations Open access
Semantic Scholar
BIDENTATE SULFOXIDE COMPLEXES OF RUTHENIUM(II) AND THEIR PRELIMINARY BIOLOGICAL ASSESSMENT IN VITRO
D. Yapp, S. Rettig, B. James, K. Skov
199721 citations
Semantic Scholar
Inactivation of the Kinase Domain of CDK10 Prevents Tumor Growth in a Preclinical Model of Colorectal Cancer, and Is Accompanied by Downregulation of Bcl-2
L. Weiswald, M. Hasan, J. C. Wong, Clarissa C. Pasiliao +11 more
2017Molecular Cancer Therapeutics20 citations Open access
Semantic Scholar
Determination of an optimal dosing schedule for combining Irinophore C™ and temozolomide in an orthotopic model of glioblastoma.
M. Verreault, Mohamed Wehbe, Dita Strutt, D. Masin +8 more
2015Journal of Controlled Release20 citations
Semantic Scholar
Synthesis, characterization, and biological studies of emissive rhenium–glutamine conjugates
Rachel Huang, Graeme Langille, R. K. Gill, C. Li +4 more
2013JBIC Journal of Biological Inorganic Chemistry19 citations
Semantic Scholar
Decreased levels of hypoxic cells in gefitinib treated ER+ HER-2 overexpressing MCF-7 breast cancer tumors are associated with hyperactivation of the mTOR pathway: therapeutic implications for combination therapy with rapamycin
W. Dragowska, M. Verreault, D. Yapp, C. Warburton +6 more
2007Breast Cancer Research and Treatment19 citations
Semantic Scholar
PEG Conjugated Zein Nanoparticles for In Vivo Use
Courtney van Ballegooie, Nicole Wretham, Tanya Ren, Ioana Popescu +2 more
2022Pharmaceutics18 citations Open access
Semantic Scholar
Synthesis and structural characterization of cis-dichlorotetrakis(tetramethylenesulfoxide-S)ruthenium(II) and mer-trichlorotris(tetrahydrothiophene)ruthenium(III)
D. Yapp, J. S. Jaswal, S. Rettig, B. James +1 more
199018 citations
Semantic Scholar
In Vivo Validation of PAPSS1 (3′-phosphoadenosine 5′-phosphosulfate synthase 1) as a Cisplatin-sensitizing Therapeutic Target
A. Leung, Chansey J. Veinotte, N. Melong, M. Oh +8 more
2017Clinical Cancer Research14 citations
Semantic Scholar
Assessment of vessel size by MRI in an orthotopic model of human pancreatic cancer
J. Flexman, A. Yung, D. Yapp, S. Ng +1 more
2008Annual International Conference of the IEEE Engineering in Medicine and Biology Society14 citations
Semantic Scholar
Imaging Tumor Vasculature Noninvasively with Positron Emission Tomography and RGD Peptides Labeled with Copper 64 Using the Bifunctonal Chelates DOTA, Oxo-DO3A. and PCTA
D. Yapp, Cara L. Ferreira, R. K. Gill, E. Boros +4 more
2013Molecular Imaging12 citations Open access
Semantic Scholar
HACE1 blocks HIF1α accumulation under hypoxia in a RAC1 dependent manner
Busra Turgu, Fan Zhang, Amal M. El-Naggar, G. Negri +13 more
2021Oncogene9 citations Open access
Semantic Scholar
Tuning the Surface Chemistry of Second-Harmonic-Active Lithium Niobate Nanoprobes Using a Silanol-Alcohol Condensation Reaction.
Rana Faryad Ali, Iris W. Guo, Henry J. H. Kang, Melissa J. Radford +2 more
2021Langmuir7 citations
Semantic Scholar
In vivo measurement of the hypoxia marker EF5 in Shionogi tumours using 19F magnetic resonance spectroscopy
M. Hoff, D. Yapp, A. Yung, Thomas Oliver +1 more
2008International Journal of Radiation Biology6 citations
Semantic Scholar
Gold–Protein Composite Nanoparticles for Enhanced X-ray Interactions: A Potential Formulation for Triggered Release
Courtney van Ballegooie, A. Man, A. Pallaoro, M. Bally +2 more
2021Pharmaceutics5 citations Open access
Semantic Scholar
Lipid-based nanoformulation of irinotecan: dual mechanism of action allows for combination chemo/angiogenic therapy.
D. Waterhouse, D. Yapp, M. Verreault, M. Anantha +2 more
2011Nanomedicine5 citations
Semantic Scholar
A Cationic Liposomal Vincristine Formulation with Improved Vincristine Retention, Extended Circulation Lifetime and Increased Anti-Tumor Activity
M. Webb, Nancy L. Boman, D. Masin, D. Yapp +4 more
20075 citations
Semantic Scholar
Recombinant T cell receptors specific for HLA-A*02:01-restricted neoepitopes containing KRAS codon 12 hotspot mutations
C. Rive, E. Yung, Christopher S. Hughes, S. Brown +12 more
2020bioRxiv4 citations Open access
Semantic Scholar
A simple route to [11C]N-Me labeling of aminosuberic acid for proof of feasibility imaging of the x(C)⁻ transporter.
Hua Yang, Q. Miao, B. F. Johnson, M. Rishel +6 more
2014Bioorganic & Medicinal Chemistry Letters4 citations
Semantic Scholar
4‐Hydroxy‐N‐methylproline
D. Yapp, J. Steed, P. Houghton
20024 citations
Semantic Scholar
Routes to ruthenium(II) bromo(sulfoxide) complexes, including the synthesis and structural characterization of a neutral dilithium/diruthenium(II) complex containing terminal and bridging tetramethylene sulfoxide ligands
J. S. Jaswal, D. Yapp, S. Rettig, B. James +1 more
19934 citations
Semantic Scholar
Synthesis and characterization of dithioethers, and their RuII and RuIII complexes
E. L. Cheu, D. Yapp, B. Patrick, B. James
2019Inorganica Chimica Acta3 citations
Semantic Scholar
Innentitelbild: An Organotrifluoroborate for Broadly Applicable One‐Step 18F‐Labeling (Angew. Chem. 44/2014)
Zhibo Liu, Maral Pourghiasian, M. Radtke, Joseph Lau +6 more
20143 citations Open access
Semantic Scholar

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