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D. Waterhouse · SciRah

Researcher profile · Semantic Scholar

D. Waterhouse

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D. Waterhouse — researcher profile on SciRah

h-index: 21
Works: 46
Citations: 2,410

Most-cited papers

Targeting tumor hypoxia: suppression of breast tumor growth and metastasis by novel carbonic anhydrase IX inhibitors.
Y. Lou, P. McDonald, A. Oloumi, S. Chia +20 more
2011Cancer Research679 citations Open access
Semantic Scholar
The liposomal formulation of doxorubicin.
Sheela A. Abraham, D. Waterhouse, L. Mayer, P. Cullis +2 more
2005Methods in Enzymology401 citations
Semantic Scholar
A Comparison of Liposomal Formulations of Doxorubicin with Drug Administered in Free Form
D. Waterhouse, P. Tardi, L. Mayer, M. Bally
2001Drug Safety238 citations
Semantic Scholar
A low carbohydrate, high protein diet slows tumor growth and prevents cancer initiation.
V. Ho, K. Leung, A. Hsu, Beryl Luk +9 more
2011Cancer Research132 citations Open access
Semantic Scholar
Development of a weak-base docetaxel derivative that can be loaded into lipid nanoparticles.
I. V. Zhigaltsev, G. Winters, M. Srinivasulu, Jason Crawford +11 more
2010Journal of Controlled Release100 citations
Semantic Scholar
QLT0267, a small molecule inhibitor targeting integrin-linked kinase (ILK), and docetaxel can combine to produce synergistic interactions linked to enhanced cytotoxicity, reductions in P-AKT levels, altered F-actin architecture and improved treatment outcomes in an orthotopic breast cancer model
J. Kalra, C. Warburton, Karen Fang, Lincoln A. Edwards +7 more
2009Breast Cancer Research79 citations Open access
Semantic Scholar
Suppression of VEGF secretion and changes in glioblastoma multiforme microenvironment by inhibition of Integrin-linked kinase (ILK)
Lincoln A. Edwards, Janet Woo, L. Huxham, M. Verreault +14 more
2008Molecular Cancer Therapeutics69 citations Open access
Semantic Scholar
Preparation, characterization, and biological analysis of liposomal formulations of vincristine.
D. Waterhouse, T. D. Madden, P. Cullis, M. Bally +2 more
2005Methods in Enzymology62 citations
Semantic Scholar
Vascular normalization in orthotopic glioblastoma following intravenous treatment with lipid-based nanoparticulate formulations of irinotecan (Irinophore C™), doxorubicin (Caelyx®) or vincristine
M. Verreault, Dita Strutt, D. Masin, M. Anantha +5 more
2011BMC Cancer60 citations Open access
Semantic Scholar
Modulation of cancer cell survival pathways using multivalent liposomal therapeutic antibody constructs
G. Chiu, Lincoln A. Edwards, A. Kapanen, Melina M. Malinen +10 more
2007Molecular Cancer Therapeutics56 citations Open access
Semantic Scholar
Liposomal Irinotecan
Corrie Lynn Messerer, E. Ramsay, D. Waterhouse, Rebecca Ng +5 more
2004Clinical Cancer Research52 citations Open access
Semantic Scholar
A novel liposomal irinotecan formulation with significant anti-tumour activity: use of the divalent cation ionophore A23187 and copper-containing liposomes to improve drug retention.
E. Ramsay, J. Alnajim, M. Anantha, J. Zastre +4 more
2008European journal of pharmaceutics and biopharmaceutics48 citations
Semantic Scholar
Irinophore C: A Liposome Formulation of Irinotecan with Substantially Improved Therapeutic Efficacy against a Panel of Human Xenograft Tumors
E. Ramsay, M. Anantha, J. Zastre, Marieke J. M. Meijs +5 more
2008Clinical Cancer Research47 citations Open access
Semantic Scholar
Substantial increases in idarubicin plasma concentration by liposome encapsulation mediates improved antitumor activity.
N. Dos Santos, D. Waterhouse, D. Masin, P. Tardi +3 more
2005Journal of Controlled Release43 citations
Semantic Scholar
Development and assessment of conventional and targeted drug combinations for use in the treatment of aggressive breast cancers.
D. Waterhouse, K. Gelmon, R. Klasa, K. Chi +11 more
2006Current Cancer Drug Targets39 citations
Semantic Scholar
Pharmacodynamic Behavior of Liposomal Antisense Oligonucleotides Targeting Her-2/neu and Vascular Endothelial Growth Factor in an Ascitic MDA435/LCC6 Human Breast Cancer Model
D. Waterhouse, W. Dragowska, K. Gelmon, L. Mayer +1 more
2004Cancer Biology & Therapy32 citations Open access
Semantic Scholar
Treatment of Colorectal Cancer Using a Combination of Liposomal Irinotecan (Irinophore C™) and 5-Fluorouracil
Jennifer I. Hare, R. Neijzen, M. Anantha, N. Dos Santos +5 more
2013PLoS ONE31 citations Open access
Semantic Scholar
Irinophore C™, a lipid-based nanoparticulate formulation of irinotecan, is more effective than free irinotecan when used to treat an orthotopic glioblastoma model.
M. Verreault, Dita Strutt, D. Masin, M. Anantha +3 more
2012Journal of Controlled Release29 citations
Semantic Scholar
HER-2/neu overexpression increases the viable hypoxic cell population within solid tumors without causing changes in tumor vascularization.
W. Dragowska, C. Warburton, D. Yapp, A. Minchinton +9 more
2004Molecular Cancer Research28 citations Open access
Semantic Scholar
Topophore C: a liposomal nanoparticle formulation of topotecan for treatment of ovarian cancer
Nilesh A. Patankar, D. Waterhouse, Dita Strutt, M. Anantha +1 more
2013Investigational new drugs27 citations
Semantic Scholar
Irinophore C™, a lipid nanoparticulate formulation of irinotecan, improves vascular function, increases the delivery of sequentially administered 5-FU in HT-29 tumors, and controls tumor growth in patient derived xenografts of colon cancer.
R. Neijzen, M. Wong, Navdeep Gill, He Wang +8 more
2015Journal of Controlled Release26 citations
Semantic Scholar
Determination of an optimal dosing schedule for combining Irinophore C™ and temozolomide in an orthotopic model of glioblastoma.
M. Verreault, Mohamed Wehbe, Dita Strutt, D. Masin +8 more
2015Journal of Controlled Release20 citations
Semantic Scholar
A Parenteral Econazole Formulation Using a Novel Micelle-to-Liposome Transfer Method: In Vitro Characterization and Tumor Growth Delay in a Breast Cancer Xenograft Model
S. Cogswell, S. Berger, D. Waterhouse, M. Bally +1 more
2006Pharmaceutical Research19 citations
Semantic Scholar
The Role of the Transition Metal Copper and the Ionophore A23187 in the Development of Irinophore C™
Nilesh A. Patankar, M. Anantha, E. Ramsay, D. Waterhouse +1 more
2011Pharmaceutical Research14 citations
Semantic Scholar
Evaluation of osmolality and pH of various concentrations of methotrexate, cytarabine, and thiotepa prepared in normal saline, sterile water for injection, and lactated Ringer's solution for intrathecal administration
M. D. de Lemos, S. Monfared, T. Denyssevych, L. Hamata +4 more
2009Journal of Oncology Pharmacy Practice14 citations Open access
Semantic Scholar
Irinophore C™, a lipid nanoparticle formulation of irinotecan, abrogates the gastrointestinal effects of irinotecan in a rat model of clinical toxicities
D. Waterhouse, Brent W. Sutherland, N. Dos Santos, D. Masin +9 more
2014Investigational new drugs13 citations Open access
Semantic Scholar
Plasma protein binding, lipoprotein distribution and uptake of free and lipid-associated BCL-2 antisense oligodeoxynucleotides (G3139) in human melanoma cells.
E. Wasan, D. Waterhouse, O. Sivak, M. Bally +2 more
2002International journal of pharmaceutics12 citations
Semantic Scholar
Nano-particulate Drug Delivery Systems for CamptothecinsArticle
Nilesh A. Patankar, D. Waterhouse
201211 citations
Semantic Scholar
Drug-Drug Interactions Arising From the Use of Liposomal Vincristine in Combination with Other Anticancer Drugs
D. Waterhouse, N. Dos Santos, L. Mayer, M. Bally
2001Pharmaceutical Research8 citations
Semantic Scholar
Lipid-based nanoformulation of irinotecan: dual mechanism of action allows for combination chemo/angiogenic therapy.
D. Waterhouse, D. Yapp, M. Verreault, M. Anantha +2 more
2011Nanomedicine5 citations
Semantic Scholar
Combining doxorubicin and liposomal anti-HER-2/NEU antisense oligodeoxynucleotides to treat HER-2/NEU-expressing MDA-MB-435 breast tumor model.
D. Waterhouse, K. Gelmon, D. Masin, M. Bally
2003Journal of experimental therapeutics and oncology5 citations
Semantic Scholar
A novel combination of Chinese medicines to treat advanced cancers and lymphomas in rats
D. Waterhouse
2009Chinese Medicine4 citations Open access
Semantic Scholar
Trastuzumab and Liposomal Doxorubicin in the Treatment of MCF-7 Xenograft Tumor-Bearing Mice: Combination Does Not Affect Drug Serum Levels
D. Waterhouse, T. Denyssevych, Norma J. Hudon, S. Chia +2 more
2005Pharmaceutical Research4 citations
Semantic Scholar
Abstract 824: In vivo efficacy of VAL-083 in the treatment of non-small cell lung cancer
A. Steinø, J. Bacha, W. Garner, S. Kanekal +3 more
20141 citations
Semantic Scholar
Abstract 5261: Irinophore C, a liposomal formulation of irinotecan, has anti-vascular effects in primary tumors of colorectal cancer grown orthotopically in mice
M. Wong, Tamanna Karim, A. Yung, P. Kozlowski +7 more
20121 citations
Semantic Scholar
Abstract B12: The effects of Irinophore C™ on the microenvironment and vasculature of a primary orthotopic model of colorectal cancer.
M. Wong, Tamanna Karim, Navdeep Gill, D. Waterhouse +5 more
20111 citations
Semantic Scholar
Optimization and Therapeutic Activity of Liposome-Conjugated Monoclonal Antibodies Against the ErbB family of Receptor Tyrosine Kinases: First Step in the Development of Therapeutic Antibody/Liposomal Anticancer Drug Combinations
G. Chiu, T. Harasym, P. Tardi, M. Bally +1 more
20061 citations
Semantic Scholar
O.16: AMF-1c-120: An antibody specific for misfolded prion protein recognizes ovarian and lung cancer cells but not normal cells
Marni D. Uger, W. Guest, A. Pataer, Li Li +17 more
20140 citations
Semantic Scholar
Abstract 455: Hypoxia induced carbonic anhydrase IX is essential for the growth and metastasis of breast tumors
Y. Lou, P. McDonald, A. Oloumi, S. Chia +14 more
20100 citations
Semantic Scholar
Retraction: a novel combination of Chinese medicines to treat advanced cancers and lymphomas tested in rats
D. Waterhouse
2010Chinese Medicine0 citations Open access
Semantic Scholar
Abstract 3661: Vascular changes and potentiating secondary drug delivery in colorectal cancer with Irinophore C
R. Neijzen, M. Wong, M. Anantha, D. Waterhouse +3 more
20100 citations
Semantic Scholar
Triggered Release of Nanoparticulate Arsenic Trioxide for Treatment of Malignant Lymphomas: Preclinical Studies
J. Winter, D. Waterhouse, R. Ahn, Haimei Chen +4 more
20080 citations
Semantic Scholar
Temporal targeting in cancer: combined chemotherapy and antiangiogenic therapy.
D. Waterhouse, M. Bally
2006Nanomedicine0 citations
Semantic Scholar
Lipid/Polymer Nanoparticles as Tools to Improve the Therapeutic Activity of Existing and Emerging Anticancer Drug Combinations
E. Ramsay, D. Waterhouse, K. Gelmon, N. D. Santos +15 more
2004International Conference on MEMS, NANO, and Smart Systems0 citations
Semantic Scholar
Sulfasalazine inhibits growth of mantle cell lymphoma cell cultures via cyst ine starvation and delays tumour growth in a newly developed murine MCL model
G. Bebb, Dan W. Doxsee, Catherine A. Tucker, D. Waterhouse +5 more
20030 citations
Semantic Scholar
Antisense oligonucleotides as therapeutics for the treatment of aggressive breast cancer
D. Waterhouse
20020 citations
Semantic Scholar

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M. Bally×37
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M. Bally — researcher profile on SciRah
M. Anantha×13
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M. Anantha — researcher profile on SciRah
D. Yapp×10
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D. Yapp — researcher profile on SciRah
D. Masin×9
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D. Masin — researcher profile on SciRah

×7

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Dita Strutt — researcher profile on SciRah

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L. Mayer — researcher profile on SciRah

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M. Webb — researcher profile on SciRah

W. Dragowska×6

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W. Dragowska — researcher profile on SciRah

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K. Gelmon — researcher profile on SciRah

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E. Ramsay — researcher profile on SciRah

A. Minchinton×5

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A. Minchinton — researcher profile on SciRah

Lincoln A. Edwards×5

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Lincoln A. Edwards — researcher profile on SciRah