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G. Heller · SciRah

Researcher profile · Semantic Scholar

G. Heller

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G. Heller — researcher profile on SciRah

h-index: 32
Works: 126
Citations: 3,395

Most-cited papers

CDK6 as a key regulator of hematopoietic and leukemic stem cell activation.
Ruth Scheicher, Andrea Hoelbl-Kovacic, F. Bellutti, Anca-Sarmiza Tigan +9 more
2015Blood237 citations Open access
Semantic Scholar
Aggressive B-cell lymphomas in patients with myelofibrosis receiving JAK1/2 inhibitor therapy
E. Porpaczy, Sabrina Tripolt, Andrea Hoelbl-Kovacic, B. Gisslinger +33 more
2018Blood143 citations Open access
Semantic Scholar
STAT5 Is a Key Regulator in NK Cells and Acts as a Molecular Switch from Tumor Surveillance to Tumor Promotion.
D. Gotthardt, E. Putz, Eva Grundschober, M. Prchal-Murphy +12 more
2016Cancer Discovery143 citations Open access
Semantic Scholar
Review of cancer treatment with immune checkpoint inhibitors
C. Thallinger, T. Füreder, M. Preusser, G. Heller +8 more
2017Wiener Klinische Wochenschrift115 citations Open access
Semantic Scholar
SPAG6 and L1TD1 are transcriptionally regulated by DNA methylation in non-small cell lung cancers
C. Altenberger, G. Heller, B. Ziegler, E. Tomasich +11 more
2017Molecular Cancer109 citations Open access
Semantic Scholar
HIF1α Regulates mTOR Signaling and Viability of Prostate Cancer Stem Cells
Maximilian Marhold, E. Tomasich, A. El-Gazzar, G. Heller +4 more
2014Molecular Cancer Research77 citations Open access
Semantic Scholar
Increased copy-number and not DNA hypomethylation causes overexpression of the candidate proto-oncogene CYP24A1 in colorectal cancer
J. Höbaus, Doris M. Hummel, U. Thiem, I. Fetahu +7 more
2013International Journal of Cancer73 citations Open access
Semantic Scholar
CDK6 antagonizes p53-induced responses during tumorigenesis
F. Bellutti, Anca-Sarmiza Tigan, S. Nebenfuehr, M. Dolezal +23 more
2018Cancer Discovery68 citations Open access
Semantic Scholar
Next-generation sequencing identifies major DNA methylation changes during progression of Ph+ chronic myeloid leukemia
G. Heller, T. Topakian, C. Altenberger, S. Cerny-Reiterer +12 more
2016Leukemia55 citations Open access
Semantic Scholar
A kinase-independent role for CDK8 in BCR-ABL1+ leukemia
Ingeborg Menzl, Ting-Hu Zhang, Angelika Berger-Becvar, R. Grausenburger +23 more
2019Nature Communications48 citations Open access
Semantic Scholar
SOCS2 is part of a highly prognostic 4-gene signature in AML and promotes disease aggressiveness
C. H. Nguyen, Tobias Glüxam, Angela Schlerka, Katharina Bauer +9 more
2019Scientific Reports47 citations Open access
Semantic Scholar
SARS-CoV-2 seroprevalence in oncology healthcare professionals and patients with cancer at a tertiary care centre during the COVID-19 pandemic
T. Fuereder, A. Berghoff, G. Heller, H. Haslacher +12 more
2020ESMO Open46 citations Open access
Semantic Scholar
A STAT5B-CD9 axis determines self-renewal in hematopoietic and leukemic stem cells.
S. Kollmann, R. Grausenburger, T. Klampfl, M. Prchal-Murphy +15 more
2021Blood39 citations Open access
Semantic Scholar
A Kinase-Independent Function of CDK6 Links the Cell Cycle to Tumor Angiogenesis
K. Kollmann, G. Heller, Christine Schneckenleithner, W. Warsch +20 more
2016Cancer Cell38 citations Open access
Semantic Scholar
Tumor DNA methylation profiles correlate with response to anti-PD-1 immune checkpoint inhibitor monotherapy in sarcoma patients
A. Starzer, A. Berghoff, R. Hamacher, E. Tomasich +13 more
2021Journal for ImmunoTherapy of Cancer36 citations Open access
Semantic Scholar
Systemic inflammation scores correlate with survival prognosis in patients with newly diagnosed brain metastases
A. Starzer, A. Steindl, M. Mair, C. Deischinger +7 more
2021British Journal of Cancer36 citations Open access
Semantic Scholar
CGRP Signaling via CALCRL Increases Chemotherapy Resistance and Stem Cell Properties in Acute Myeloid Leukemia
Tobias Gluexam, A. Grandits, Angela Schlerka, C. H. Nguyen +12 more
2019International Journal of Molecular Sciences35 citations Open access
Semantic Scholar
IDO1+ Paneth cells promote immune escape of colorectal cancer
Sandra Pflügler, J. Svinka, Irene Scharf, Ilija Crnčec +24 more
2020Communications Biology34 citations Open access
Semantic Scholar
microRNA‐146a controls age‐related bone loss
V. Saferding, M. Hofmann, J. Brunner, B. Niederreiter +13 more
2020Aging Cell33 citations Open access
Semantic Scholar
Differential prognostic impact of interleukin-34 mRNA expression and infiltrating immune cell composition in intrinsic breast cancer subtypes
K. Zins, G. Heller, M. Mayerhofer, Martin Schreiber +1 more
2018OncoTarget33 citations Open access
Semantic Scholar
DNA methylation of microRNA‐coding genes in non‐small‐cell lung cancer patients
G. Heller, C. Altenberger, I. Steiner, T. Topakian +10 more
2018Journal of Pathology32 citations Open access
Semantic Scholar
Epigenetic down‐regulation of integrin α7 increases migratory potential and confers poor prognosis in malignant pleural mesothelioma
V. Laszlo, M. Hoda, T. Garay, C. Pirker +21 more
2015Journal of Pathology31 citations
Semantic Scholar
EVI1 promotes tumor growth via transcriptional repression of MS4A3
G. Heller, Anna Rommer, Katarina Steinleitner, J. Etzler +12 more
2015Journal of Hematology & Oncology31 citations Open access
Semantic Scholar
Favourable outcome of patients with breast cancer brain metastases treated with dual HER2 blockade of trastuzumab and pertuzumab
E. Bergen, Amelie Binter, A. Starzer, G. Heller +12 more
2021Therapeutic Advances in Medical Oncology27 citations Open access
Semantic Scholar
IL2RA Promotes Aggressiveness and Stem Cell–Related Properties of Acute Myeloid Leukemia
C. H. Nguyen, Angela Schlerka, A. Grandits, E. Koller +5 more
2020Cancer Research27 citations
Semantic Scholar
Frequent overexpression of HER3 in brain metastases from breast and lung cancer.
E. Tomasich, A. Steindl, C. Paiato, T. Hatziioannou +11 more
2023Clinical Cancer Research26 citations Open access
Semantic Scholar
DNA methylation profiles differ in responders versus non-responders to anti-PD-1 immune checkpoint inhibitors in patients with advanced and metastatic head and neck squamous cell carcinoma
A. Starzer, G. Heller, E. Tomasich, T. Melchardt +10 more
2022Journal for ImmunoTherapy of Cancer23 citations Open access
Semantic Scholar
Degradation of BRD4 - a promising treatment approach not only for hematologic but also for solid cancer.
K. Bauer, A. Berghoff, M. Preusser, G. Heller +3 more
2021American Journal of Cancer Research23 citations
Semantic Scholar
Myeloid lncRNA LOUP Mediates Opposing Regulatory Effects of RUNX1 and RUNX1-ETO in t(8;21) AML.
B. Trinh, S. Ummarino, Yan-Zhou Zhang, A. Ebralidze +24 more
2021Blood22 citations Open access
Semantic Scholar
DNA methylation transcriptionally regulates the putative tumor cell growth suppressor ZNF677 in non-small cell lung cancers
G. Heller, C. Altenberger, B. Schmid, Maximilian Marhold +14 more
2014OncoTarget22 citations Open access
Semantic Scholar
Tumor mutational burden and immune infiltrates in renal cell carcinoma and matched brain metastases
A. Steindl, D. Alpár, G. Heller, M. Mair +9 more
2021ESMO Open21 citations Open access
Semantic Scholar
EGFR Controls Hair Shaft Differentiation in a p53-Independent Manner
N. Amberg, P. Sotiropoulou, G. Heller, B. Lichtenberger +5 more
2019iScience20 citations Open access
Semantic Scholar
Inhibitory CARs fail to protect from immediate T cell cytotoxicity
Maximilian A Funk, G. Heller, Petra Waidhofer-Söllner, J. Leitner +1 more
2024Molecular Therapy18 citations Open access
Semantic Scholar
Pembrolizumab plus docetaxel for the treatment of recurrent/metastatic head and neck cancer: A prospective phase I/II study.
T. Fuereder, C. Minichsdorfer, M. Mittlboeck, C. Wagner +7 more
2021Oral Oncology18 citations Open access
Semantic Scholar
Triple-negative breast cancer cells rely on kinase-independent functions of CDK8 to evade NK-cell-mediated tumor surveillance
V. M. Knab, D. Gotthardt, Klara Klein, R. Grausenburger +8 more
2021Cell Death and Disease18 citations Open access
Semantic Scholar
DNA Methylation Signatures Correlate with Response to Immune Checkpoint Inhibitors in Metastatic Melanoma
J. Ressler, E. Tomasich, T. Hatziioannou, H. Ringl +9 more
2024Targeted oncology17 citations Open access
Semantic Scholar
New perspectives on biology, disease progression, and therapy response of head and neck cancer gained from single cell RNA sequencing and spatial transcriptomics
G. Heller, T. Fuereder, A. Grandits, Rotraud Wieser
2023Oncology Research17 citations Open access
Semantic Scholar
CDK6 Degradation Is Counteracted by p16INK4A and p18INK4C in AML
B. Schmalzbauer, T. Thondanpallil, G. Heller, A. Schirripa +10 more
2022Cancers16 citations Open access
Semantic Scholar
The FAM3C locus that encodes interleukin-like EMT inducer (ILEI) is frequently co-amplified in MET-amplified cancers and contributes to invasiveness
U. Schmidt, G. Heller, G. Timelthaler, P. Heffeter +5 more
2020Journal of experimental & clinical cancer research : CR16 citations Open access
Semantic Scholar
Pharmacological Inhibition of Lipid Import and Transport Proteins in Ovarian Cancer
Lisa Lemberger, R. Wagner, G. Heller, Dietmar Pils +1 more
2022Cancers15 citations Open access
Semantic Scholar
Down-regulation of MTSS1 in acute myeloid leukemia is associated with a poor prognosis, chemotherapy resistance, and disease aggressiveness
A. Grandits, C. H. Nguyen, Angela Schlerka, H. Hackl +7 more
2021Leukemia15 citations Open access
Semantic Scholar
Loss of HCRP1 leads to upregulation of PD-L1 via STAT3 activation and is of prognostic significance in EGFR-dependent cancer.
E. Tomasich, T. Topakian, G. Heller, Simon Udovica +2 more
2020Translational Research: The Journal of Laboratory and Clinical Medicine13 citations Open access
Semantic Scholar
CDK6 kinase inhibition unmasks metabolic dependencies in BCR::ABL1+ leukemia
Lisa Scheiblecker, Thorsten Klampfl, E. Doma, S. Nebenfuehr +14 more
2025Cell Death and Disease12 citations Open access
Semantic Scholar
Kinase-inactivated CDK6 preserves the long-term functionality of adult hematopoietic stem cells
I. Mayer, E. Doma, Thorsten Klampfl, M. Prchal-Murphy +16 more
2024Blood12 citations Open access
Semantic Scholar
Loss of NKG2D in murine NK cells leads to increased perforin production upon long‐term stimulation with IL‐2
D. Prinz, Klara R. Klein, J. List, V. M. Knab +8 more
2019European Journal of Immunology12 citations Open access
Semantic Scholar
STAT5BN642H drives transformation of NKT cells: a novel mouse model for CD56+ T-LGL leukemia
Klara R. Klein, A. Witalisz-Siepracka, B. Maurer, D. Prinz +6 more
2019Leukemia12 citations Open access
Semantic Scholar
Core binding factor leukemia hijacks T-cell prone PU.1 antisense promoter.
E. van der Kouwe, G. Heller, A. Czibere, J. Pulikkan +29 more
2021Blood11 citations Open access
Semantic Scholar
Core binding factor leukemia hijacks T-cell prone PU.1 antisense promoter
E. van der Kouwe, G. Heller, A. Czibere, L. Castilla +22 more
2020bioRxiv11 citations Open access
Semantic Scholar
Early postoperative treatment versus initial observation in CNS WHO grade 2 and 3 oligodendroglioma: clinical outcomes and DNA methylation patterns.
M. Mair, A. Leibetseder, G. Heller, R. Puhr +13 more
2022Clinical Cancer Research10 citations Open access
Semantic Scholar
Myeloid lncRNA LOUP Mediates Opposing Regulatory Effects of RUNX1 and RUNX1-ETO in t(8;21) AML
B. Trinh, S. Ummarino, A. Ebralidze, E. van der Kouwe +23 more
2020bioRxiv10 citations Open access
Semantic Scholar

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