Jill M. Marinis

Most-cited papers

1. Autophagy protein ATG16L1 prevents necroptosis in the intestinal epithelium

   Yu Matsuzawa-Ishimoto, Y. Shono, Luis E. Gomez, Vanessa M. Hubbard-Lucey +13 more

   2017Journal of Experimental Medicine272 citations Open access

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2. Integrator Regulates Transcriptional Initiation and Pause Release Following Activation

   Alessandro Gardini, David Baillat, M. Cesaroni, D. Hu +5 more

   2014Molecules and Cells186 citations Open access

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3. RIP1 Kinase Drives Macrophage-Mediated Adaptive Immune Tolerance in Pancreatic Cancer.

   Wei Wang, Jill M. Marinis, A. Beal, Shivraj Savadkar +37 more

   2020Cancer Cell170 citations Open access

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4. ITCH directly K63-ubiquitinates the NOD2 binding protein, RIP2, to influence inflammatory signaling pathways

   M. Tao, P. Scacheri, Jill M. Marinis, E. Harhaj +2 more

   2009Current Biology149 citations Open access

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5. PPARγ is a nexus controlling alternative activation of macrophages via glutamine metabolism

   V. Nelson, Hoang C B Nguyen, J. García-Cañaveras, Erika R. Briggs +5 more

   2018Genes & Development132 citations Open access

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6. Genetic Variation Determines PPARγ Function and Antidiabetic Drug Response In Vivo

   Raymond E. Soccio, Eric R. Chen, Satyajit R. Rajapurkar, Pegah Safabakhsh +13 more

   2015Cell122 citations Open access

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7. Dysregulation of a long noncoding RNA reduces leptin leading to a leptin-responsive form of obesity

   Olof S. Dallner, Jill M. Marinis, Yi-Hsueh Lu, Kıvanç Birsoy +15 more

   2019Nature Medicine102 citations

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8. Anti-diabetic rosiglitazone remodels the adipocyte transcriptome by redistributing transcription to PPARγ-driven enhancers

   Sonia E. Step, H. Lim, Jill M. Marinis, A. Prokesch +4 more

   2014Genes & Development99 citations Open access

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9. RIP1 Kinase Drives Macrophage Mediated Adaptive Immune Tolerance in Pancreatic Cancer

   Wei Wang, Jill M. Marinis, A. Beal, Shivraj Savadkar +37 more

   2018Cancer Cell84 citations Open access

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10. Identification of a RIP1 Kinase Inhibitor Clinical Candidate (GSK3145095) for the Treatment of Pancreatic Cancer

    P. Harris, Jill M. Marinis, J. Lich, Scott B. Berger +24 more

    2019ACS Medicinal Chemistry Letters82 citations Open access

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11. A Novel Motif in the Crohn's Disease Susceptibility Protein, NOD2, Allows TRAF4 to Down-regulate Innate Immune Responses*

    Jill M. Marinis, C. Homer, C. McDonald, Derek W. Abbott

    2010Journal of Biological Chemistry75 citations Open access

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12. MEKK4 sequesters RIP2 to dictate signal specificity downstream of the Crohn’s Disease Susceptibility Protein, NOD2

    Nivedita M. Clark, Jill M. Marinis, B. Cobb, Derek W. Abbott

    2008Current Biology34 citations Open access

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13. IκB Kinase α Phosphorylation of TRAF4 Downregulates Innate Immune Signaling

    Jill M. Marinis, Jessica E. Hutti, C. Homer, B. Cobb +3 more

    2012Molecular and Cellular Biology33 citations Open access

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14. Innate Immune-Directed NF-κB Signaling Requires Site-Specific NEMO Ubiquitination

    Janice C. Jun, S. Kertesy, Mark B. Jones, Jill M. Marinis +3 more

    2013Cell Reports16 citations Open access

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15. A phase I/II study of GSK3145095 alone and in combination with anticancer agents including pembrolizumab in adults with selected solid tumors.

    D. Cohen, S. Pant, B. O'Neil, Jill M. Marinis +8 more

    2019Journal of Clinical Oncology3 citations

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16. Application of DMPK toolbox in predicting human pharmacokinetics for back-up RIP1 inhibitors: Learnings from GSK2982772 in clinic

    M. Mahajan, Phillip A. Harris, David Zhang, L. Richards-Peterson +7 more

    2019Drug Metabolism and Pharmacokinetics0 citations

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17. Genome-wide analysis of enhancer-RNA transcription reveals regulatory mechanisms by an anti-diabetic drug in adipocyte

    H. Lim, Sonia E. Step, Jill M. Marinis, A. Prokesch +4 more

    20140 citations

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18. Negative Regulation of NOD2 Signaling

    Jill M. Marinis

    20120 citations

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19. Tu1900 Defective NOD2 Signaling and Innate Cytokine Production in Response to MDP in Experimental Crohn's Disease (CD)

    D. Corridoni, Jill M. Marinis, Derek W. Abbott, F. Cominelli

    20120 citations

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20. I (cid:1) B Kinase (cid:2) Phosphorylation of TRAF4 Downregulates Innate Immune Signaling

    Jill M. Marinis, Jessica E. Hutti, C. Homer, B. Cobb +3 more

    20120 citations

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21. I (cid:1) B Kinase (cid:2) Phosphorylation of TRAF4 Downregulates Innate Immune Signaling

    Jill M. Marinis, Jessica E. Hutti, C. Homer, B. Cobb +3 more

    20120 citations

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22. CS05-5. Defective Nod2 Signaling And Innate Cytokine Production In Response To Mdp In Experimental Crohn’s Disease (CD)

    D. Corridoni, Jill M. Marinis, Derek W. Abbott, F. Cominelli

    20110 citations

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23. Targeting inhibitors of NOD2 signaling to allow productive inflammation in genetic inflammatory disease (157.9)

    Jill M. Marinis, C. Homer, C. McDonald, Derek W. Abbott

    2011Journal of Immunology0 citations

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