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E. Margheritis · SciRah

Researcher profile · Semantic Scholar

E. Margheritis

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E. Margheritis — researcher profile on SciRah

h-index: 13
Works: 33
Citations: 621

Most-cited papers

Transplantation of gasdermin pores by extracellular vesicles propagates pyroptosis to bystander cells
Skylar S. Wright, Puja Kumari, Víctor Fraile-Ágreda, Cheng-Liang Wang +12 more
2024Cell117 citations Open access
Semantic Scholar
Two Na+ Sites Control Conformational Change in a Neurotransmitter Transporter Homolog*
Sotiria Tavoulari, E. Margheritis, Anu Nagarajan, David C. DeWitt +6 more
2015Journal of Biological Chemistry70 citations Open access
Semantic Scholar
NMR-Guided Directed Evolution
Sagar Bhattacharya, E. Margheritis, Katsuya Takahashi, Alona Kulesha +7 more
2021Nature57 citations Open access
Semantic Scholar
Atg9 interactions via its transmembrane domains are required for phagophore expansion during autophagy
Sabrina Chumpen Ramirez, R. Gómez-Sánchez, Pauline Verlhac, Ralph Hardenberg +4 more
2022Autophagy49 citations Open access
Semantic Scholar
Bile Acid Recognition by NAPE-PLD
E. Margheritis, B. Castellani, P. Magotti, Sara Peruzzi +6 more
2016ACS Chemical Biology41 citations Open access
Semantic Scholar
Nanobeam precession-assisted 3D electron diffraction reveals a new polymorph of hen egg-white lysozyme
A. Lanza, E. Margheritis, E. Mugnaioli, V. Cappello +2 more
2019IUCrJ37 citations Open access
Semantic Scholar
Gasdermin D cysteine residues synergistically control its palmitoylation-mediated membrane targeting and assembly
E. Margheritis, Shirin Kappelhoff, John S. H. Danial, Nadine Gehle +4 more
2024EMBO Journal34 citations Open access
Semantic Scholar
New insights into Gasdermin D pore formation.
Shirin Kappelhoff, E. Margheritis, Katia Cosentino
2024Biochemical Society Transactions26 citations
Semantic Scholar
Pore-Forming Proteins: From Pore Assembly to Structure by Quantitative Single-Molecule Imaging
E. Margheritis, Shirin Kappelhoff, Katia Cosentino
2023International Journal of Molecular Sciences24 citations Open access
Semantic Scholar
Functional properties of a newly cloned fish ortholog of the neutral amino acid transporter B0AT1 (SLC6A19).
E. Margheritis, G. Terova, R. Cinquetti, A. Peres +1 more
2013Comparative biochemistry and physiology. Part A, Molecular & integrative physiology20 citations Open access
Semantic Scholar
Characterization of the transport of lysine-containing dipeptides by PepT1 orthologs expressed in Xenopus laevis oocytes.
E. Margheritis, G. Terova, Ayodele Oyadeyi, M. Renna +3 more
2013Comparative biochemistry and physiology. Part A, Molecular & integrative physiology19 citations Open access
Semantic Scholar
Amino acid transporter B0AT1 (slc6a19) and ancillary protein: impact on function
E. Margheritis, F. Imperiali, R. Cinquetti, Alessandra Vollero +4 more
2016Pflügers Archiv: European Journal of Physiology18 citations
Semantic Scholar
Role of Gln222 in Photoswitching of Aequorea Fluorescent Proteins: A Twisting and H-Bonding Affair?
B. Storti, E. Margheritis, Gerardo Abbandonato, G. Domenichini +5 more
2018ACS Chemical Biology13 citations Open access
Semantic Scholar
Temperature effects on the kinetic properties of the rabbit intestinal oligopeptide cotransporter PepT1
E. Bossi, F. Cherubino, E. Margheritis, Ayodele Oyadeyi +2 more
2012Pflügers Archiv: European Journal of Physiology13 citations
Semantic Scholar
NAPE-PLD is target of thiazide diuretics.
S. Chiarugi, Francesco Margheriti, Valentina De Lorenzi, Elisa Martino +12 more
2025Cell Chemical Biology11 citations
Semantic Scholar
Development of potent dual PDK1/AurA kinase inhibitors for cancer therapy: Lead-optimization, structural insights, and ADME-Tox profile.
S. Sestito, A. Bacci, S. Chiarugi, Massimiliano Runfola +10 more
2021European journal of medicinal chemistry9 citations Open access
Semantic Scholar
Systematic Assessment of the Accuracy of Subunit Counting in Biomolecular Complexes Using Automated Single-Molecule Brightness Analysis
J. Danial, Y. Quintana, Uris Ros, R. Shalaby +5 more
2021bioRxiv9 citations Open access
Semantic Scholar
The D‐amino acid transport by the invertebrate SLC6 transporters KAAT1 and CAATCH1 from Manduca sexta
Alessandra Vollero, F. Imperiali, R. Cinquetti, E. Margheritis +2 more
2016Physiological Reports9 citations Open access
Semantic Scholar
Evaluation of DIBMA nanoparticles of variable size and anionic lipid content as tools for the structural and functional study of membrane proteins.
N. Voskoboynikova, E. Margheritis, F. Kodde, Malte Rademacher +5 more
2021Biochimica et Biophysica Acta - Biomembranes8 citations Open access
Semantic Scholar
Silica-Based Nanoparticles for Protein Encapsulation and Delivery
Filippo Begarani, Domenico Cassano, E. Margheritis, R. Marotta +2 more
2018Nanomaterials8 citations Open access
Semantic Scholar
Gasdermins: multifunctional effectors of membrane permeabilization across cellular compartments
E. Margheritis, Nadine Gehle, Katia Cosentino
2025The FEBS Journal7 citations Open access
Semantic Scholar
Structure and regulation of GSDMD pores at the plasma membrane of pyroptotic cells
Shirin Kappelhoff, Michael Holtmannspötter, Stefan L. Schäfer, E. Margheritis +10 more
2023bioRxiv7 citations Open access
Semantic Scholar
An Inverse Relationship Links Temperature and Substrate Apparent Affinity in the Ion-Coupled Cotransporters rGAT1 and KAAT1
A. Peres, Alessandra Vollero, E. Margheritis, F. D’Antoni +1 more
2012International Journal of Molecular Sciences5 citations Open access
Semantic Scholar
Amino acid transporter B0AT1 (slc6a19) and ancillary protein: impact on function
E. Margheritis, F. Imperiali, R. Cinquetti, Alessandra Vollero +4 more
2016Pflügers Archiv: European Journal of Physiology3 citations
Semantic Scholar
Temperature effects on the kinetic properties of the rabbit intestinal oligopeptide cotransporter PepT1
E. Bossi, F. Cherubino, E. Margheritis, Ayodele Oyadeyi +2 more
2012Pflügers Archiv: European Journal of Physiology3 citations
Semantic Scholar
Direct visualization of native GSDMD pores reveals lipid-driven stabilization during pyroptosis
Shirin Kappelhoff, Michael Holtmannspötter, Stefan L. Schäfer, E. Margheritis +15 more
2026Science Advances2 citations Open access
Semantic Scholar
Nanoscale PI(4,5)P2 partitioning driven by FGF2 oligomerization triggers membrane pore formation
A. Griffo, Daniel Beyer, Jaime Fernández Sobaberas, M. König +9 more
2025bioRxiv2 citations Open access
Semantic Scholar
Novel Dual PDK1/AurK-A Inhibitors for Cancer Therapy: Med Chem Evolution and Crystallographic Investigation
S. Sestito, S. Chiarugi, E. Margheritis, Massimiliano Runfola +3 more
2019Proceedings2 citations Open access
Semantic Scholar
Structural mechanism of Gasdermin E-mediated mtDNA release from apoptotic mitochondria
Lisa Hohorst, R. Shalaby, Nadine Gehle, Zakarya Benayad +20 more
2026bioRxiv0 citations Open access
Semantic Scholar
SPECTROSCOPIC AND STRUCTURAL STUDY OF QW, A EGFP MUTANT SHOWING PHOTOSWITCHING PROPERTIES
G. Garau, E. Margheritis
20190 citations
Semantic Scholar
Nanobeam precession-assisted 3D electron diffraction reveals a new lysozyme polymorph
A. Lanza, V. Cappello, E. Margheritis, E. Mugnaioli +2 more
2018Acta Crystallographica Section A: Foundations and Advances0 citations Open access
Semantic Scholar
Acid by
E. Margheritis, B. Castellani, Paola Magotti, Sara Peruzzi +6 more
20160 citations
Semantic Scholar
Molecular cloning and kinetic characterization of fish amino acid transporter B0AT1 (SLC6A19)
E. Margheritis, R. Cinquetti, G. Terova, A. Cardillo +2 more
20130 citations
Semantic Scholar

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Katia Cosentino×12
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E. Bossi×9
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Shirin Kappelhoff×7
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