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L. Debusk · SciRah

Researcher profile · Semantic Scholar

L. Debusk

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L. Debusk — researcher profile on SciRah

h-index: 18
Works: 37
Citations: 2,975

Most-cited papers

Expansion of myeloid immune suppressor Gr+CD11b+ cells in tumor-bearing host directly promotes tumor angiogenesis.
Li Yang, L. Debusk, K. Fukuda, B. Fingleton +5 more
2004Cancer Cell1,180 citations Open access
Semantic Scholar
Presence of soluble amyloid β–peptide precedes amyloid plaque formation in Down's syndrome
J. Teller, C. Russo, L. Debusk, G. Angelini +7 more
1996Nature Medicine341 citations
Semantic Scholar
Quantitative pharmacokinetic analysis of DCE-MRI data without an arterial input function: a reference region model.
T. Yankeelov, J. Luci, M. Lepage, Rui Li +4 more
2005Magnetic Resonance Imaging312 citations
Semantic Scholar
EP2, a receptor for PGE2, regulates tumor angiogenesis through direct effects on endothelial cell motility and survival
M. Kamiyama, A. Pozzi, Li Yang, L. Debusk +2 more
2006Oncogene130 citations Open access
Semantic Scholar
Heterogeneity of water‐soluble amyloid β‐peptide in Alzheimer's disease and Down's syndrome brains
C. Russo, T. Saido, L. Debusk, M. Tabaton +2 more
1997FEBS Letters130 citations Open access
Semantic Scholar
Akt is a major angiogenic mediator downstream of the Ang1/Tie2 signaling pathway.
L. Debusk, D. Hallahan, P. Lin
2004Experimental Cell Research126 citations
Semantic Scholar
Tie2 receptor tyrosine kinase, a major mediator of tumor necrosis factor alpha-induced angiogenesis in rheumatoid arthritis.
L. Debusk, Ying Chen, T. Nishishita, Jin Chen +2 more
2003Arthritis & Rheumatism116 citations
Semantic Scholar
Hepatocyte growth factor mediates angiopoietin-induced smooth muscle cell recruitment.
Hanako Kobayashi, L. Debusk, Y. Babichev, D. Dumont +1 more
2006Blood97 citations Open access
Semantic Scholar
Dual functional roles of Tie-2/angiopoietin in TNF-α-mediated angiogenesis
Jian-Xiong Chen, Ying Chen, L. Debusk, Wenyu Lin +1 more
200476 citations
Semantic Scholar
Gene therapy targeting the Tie2 function ameliorates collagen-induced arthritis and protects against bone destruction.
Ying Chen, E. Donnelly, Hanako Kobayashi, L. Debusk +1 more
2005Arthritis & Rheumatism73 citations
Semantic Scholar
Repeatability of a reference region model for analysis of murine DCE‐MRI data at 7T
T. Yankeelov, L. Debusk, D. Billheimer, J. Luci +3 more
2006Journal of Magnetic Resonance Imaging67 citations
Semantic Scholar
Oncogenic Mutations Regulate Tumor Microenvironment through Induction of Growth Factors and Angiogenic Mediators
S. E. Wang, Yang Yu, Tracy Criswell, L. Debusk +5 more
2010Oncogene48 citations Open access
Semantic Scholar
Dual functional roles of Tie-2/angiopoietin in TNF-alpha-mediated angiogenesis.
Jian-Xiong Chen, Ying Chen, L. Debusk, Wenyu Lin +1 more
2004American Journal of Physiology. Heart and Circulatory Physiology48 citations
Semantic Scholar
A Randomized, Double‐Blinded, Phase II Trial of Gemcitabine and Nab‐Paclitaxel Plus Apatorsen or Placebo in Patients with Metastatic Pancreatic Cancer: The RAINIER Trial
Andrew H. Ko, P. Murphy, J. Peyton, D. Shipley +11 more
2017The Oncologist47 citations Open access
Semantic Scholar
Incorporating the effects of transcytolemmal water exchange in a reference region model for DCE‐MRI analysis: Theory, simulations, and experimental results
T. Yankeelov, J. Luci, L. Debusk, P. C. Lin +1 more
2008Magnetic Resonance in Medicine45 citations Open access
Semantic Scholar
Rituximab with or without bevacizumab for the treatment of patients with relapsed follicular lymphoma.
J. Hainsworth, F. Greco, E. Raefsky, D. Thompson +6 more
2014Clinical Lymphoma, Myeloma & Leukemia26 citations
Semantic Scholar
IkappaB kinase-alpha regulates endothelial cell motility and tumor angiogenesis.
L. Debusk, P. Massion, P. Lin
2008Cancer Research23 citations Open access
Semantic Scholar
Heterozygous deficiency of δ-catenin impairs pathological angiogenesis
L. Debusk, Kimberly C. Boelte, Yong-Fen Min, P. Lin
2010Journal of Experimental Medicine18 citations Open access
Semantic Scholar
Cabazitaxel Plus Lapatinib as Therapy for HER2+ Metastatic Breast Cancer With Intracranial Metastases: Results of a Dose‐finding Study
D. Yardley, L. Hart, P. Ward, Gail L. Wright +4 more
2018Clinical Breast Cancer15 citations
Semantic Scholar
Spontaneous immortalization of human dermal microvascular endothelial cells.
M. Jiang, Yong-Fen Min, L. Debusk, Suzanne Fernandez +3 more
2010World Journal of Stem Cells12 citations Open access
Semantic Scholar
A Randomized Phase II Study of Eribulin/Cyclophosphamide or Docetaxel/Cyclophosphamide as Neoadjuvant Therapy in Operable HER2‐negative Breast Cancer
D. Yardley, D. Shipley, J. Zubkus, Gail L. Wright +6 more
2019Clinical Breast Cancer8 citations
Semantic Scholar
A Phase II Open Label Study of Everolimus in Combination With Endocrine Therapy in Resistant Hormone Receptor-Positive HER2-Negative Advanced Breast Cancer.
D. Yardley, W. Liggett, M. Mainwaring, A. Castrellon +8 more
2019Clinical Breast Cancer8 citations
Semantic Scholar
Phase II trial of eribulin in patients who do not achieve pathologic complete response (pCR) following neoadjuvant chemotherapy
D. Yardley, N. Peacock, B. Daniel, Betrand Anz +9 more
2020Breast Cancer Research and Treatment5 citations
Semantic Scholar
Abstract P5-14-04: A phase 2 study evaluating orteronel, an inhibitor of androgen biosynthesis, in patients with androgen receptor (AR)-expressing metastatic breast cancer: Interim analysis
D. Yardley, N. Peacock, R. Young, A. Silber +8 more
20165 citations
Semantic Scholar
Angiopoietin/Tie2 Signaling Regulates Tumor Angiogenesis
Hanako Kobayashi, L. Debusk, P. Lin
20083 citations
Semantic Scholar
Expansion of Myeloid Immune Suppressor Cells in Tumor-bearing Host Directly Promotes Tumor Angiogenesis, Tumor Growth, and Metastasis
P. Lin, L. Debusk, Jian-Hua Huang, L. Matrisian +3 more
20073 citations
Semantic Scholar
Array-Based Comparative Genomic Hybridization (aCGH) In Myelofibrosis Reveals Divergent Genetic Copy Number Alterations Among Patients With Post-Essential Thrombocythemia-Myelofibrosis/Post-Polycythemia Rubra Vera-Myelofibrosis (PET-MF and PPV-MF) and Patients With Idiopathic Myelofibrosis
Zeqiang Ma, L. Debusk, Pranil K. Chandra, Shile Liang +6 more
20132 citations
Semantic Scholar
In the forefront of basic and translational cancer research: Seventh Joint Conference of the American Association for Cancer Research and the Japanese Cancer Association.
L. Debusk, A. Russell, K. Imai, L. Matrisian
2007Cancer Research2 citations
Semantic Scholar
Hepatocyte Growth Factor Mediates Angiopoietin-induced Smooth Muscle Cells Recruitment
Hanako Kobayashi, L. Debusk, Y. Babichev, D. Dumont +1 more
20062 citations
Semantic Scholar
Incorporating the Effects of Transcytolemmal Water Exchange in the Reference Region Model for DCE-MRI Analysis
T. Yankeelov, L. Debusk, P. C. Lin, J. Gore
20062 citations
Semantic Scholar
A randomized, double-blinded, placebo-controlled phase II trial of gemcitabine (gem) plus nab-paclitaxel (nab-P) plus apatorsen (A) or placebo (Pl) in patients (pts) with metastatic pancreatic cancer (mPC): The RAINIER trial.
Andrew H. Ko, P. Murphy, J. Peyton, D. Shipley +11 more
20161 citations
Semantic Scholar
Abstract P1-12-04: A phase 2 study of eribulin in breast cancer not achieving a pathologic complete response (pCR) to neoadjuvant chemotherapy (NAC)
D. Yardley, N. Peacock, S. Shroff, D. Molthrop +12 more
20161 citations
Semantic Scholar
Abstract P1-14-06: A phase II randomized study with eribulin/cyclophosphamide (ErC) and docetaxel/cyclophosphamide (TC) as neoadjuvant therapy in HER2-negative breast cancer- Final analysis of primary endpoint and correlative analysis results
D. Yardley, Pranil K. Chandra, L. Hart, G. Wright +8 more
20161 citations
Semantic Scholar
Abstract P4-22-09: A phase 2 open label study of everolimus in combination with endocrine therapy in resistant hormone receptor-positive HER2-negative advanced breast cancer
D. Yardley, L. Blakely, B. Hemphill, M. Joseph +8 more
20170 citations
Semantic Scholar
Abstract OT2-1-08: A phase II open label study of everolimus in combination with anti-estrogen therapy in hormone receptor-positive HER2-negative advanced breast cancer
D. Yardley, M. Shastry, L. Debusk, H. Burris +1 more
20150 citations
Semantic Scholar
A phase II study with lead-in safety cohort of cabazitaxel (C) plus lapatinib (L) as therapy for HER2+ metastatic breast cancer (MBC) with intracranial metastases (mets).
D. Yardley, J. Hainsworth, E. Hamilton, L. Hart +3 more
20140 citations
Semantic Scholar
Heterozygous deficiency of δ-catenin impairs pathological angiogenesis
L. Debusk, Kimberly C. Boelte, Yong-Fen Min, P. Lin
2010Journal of Experimental Medicine0 citations Open access
Semantic Scholar

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