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Iryna Lebedyeva · SciRah

Researcher profile · Semantic Scholar

Iryna Lebedyeva

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Iryna Lebedyeva — researcher profile on SciRah

h-index: 16
Works: 57
Citations: 770

Most-cited papers

Blocking myristoylation of Src inhibits its kinase activity and suppresses prostate cancer progression
Sungjin Kim, O. Alsaidan, O. Goodwin, Qianjin Li +12 more
2017Cancer Research83 citations Open access
Semantic Scholar
Ceramide activates lysosomal cathepsin B and cathepsin D to attenuate autophagy and induces ER stress to suppress myeloid-derived suppressor cells
Fei-Yan Liu, Xia Li, Chun-Wan Lu, A. Bai +6 more
2016OncoTarget81 citations Open access
Semantic Scholar
CXCR2-Expressing Tumor Cells Drive Vascular Mimicry in Antiangiogenic Therapy–Resistant Glioblastoma
Kartik Angara, T. Borin, M. Rashid, Iryna Lebedyeva +6 more
2018Neoplasia68 citations Open access
Semantic Scholar
SUV39H1 represses the expression of cytotoxic T-lymphocyte effector genes to promote colon tumor immune evasion
Chun-Wan Lu, Da-Feng Yang, John D. Klement, Kyu Oh +13 more
2019Cancer immunology research57 citations Open access
Semantic Scholar
Targeting TREM1 augments antitumor T cell immunity by inhibiting myeloid-derived suppressor cells and restraining anti–PD-1 resistance
Ashwin Ajith, K. Mamouni, D. D. Horuzsko, A. Musa +7 more
2023Journal of Clinical Investigation55 citations Open access
Semantic Scholar
Multi-kinase inhibitors can associate with heat shock proteins through their NH2-termini by which they suppress chaperone function
Laurence A. Booth, B. Shuch, T. Albers, Jane L. Roberts +9 more
2016OncoTarget47 citations Open access
Semantic Scholar
SUV39H1 regulates human colon carcinoma apoptosis and cell cycle to promote tumor growth
Chun-Wan Lu, John D. Klement, Da-Feng Yang, T. Albers +3 more
2020Cancer Letters41 citations Open access
Semantic Scholar
Magnetic nanoparticles as a new approach to improve the efficacy of gene therapy against differentiated human uterine fibroid cells and tumor-initiating stem cells
S. Shalaby, Mostafa Khater, Aymara Mas Perucho, S. Mohamed +6 more
2016Fertility and Sterility37 citations Open access
Semantic Scholar
HET0016 decreases lung metastasis from breast cancer in immune-competent mouse model
T. Borin, Adarsh Shankar, Kartik Angara, M. Rashid +7 more
2017PLoS ONE27 citations Open access
Semantic Scholar
Intravenous Formulation of HET0016 Decreased Human Glioblastoma Growth and Implicated Survival Benefit in Rat Xenograft Models
Meenu Jain, N. H. Gamage, M. Alsulami, Adarsh Shankar +13 more
2017Scientific Reports26 citations Open access
Semantic Scholar
Ceramide mediates FasL-induced caspase 8 activation in colon carcinoma cells to enhance FasL-induced cytotoxicity by tumor-specific cytotoxic T lymphocytes
Genevieve L. Coe, Priscilla S. Redd, A. Paschall, Chun-Wan Lu +5 more
2016Scientific Reports25 citations Open access
Semantic Scholar
Pharmacologically targeting the myristoylation of the scaffold protein FRS2α inhibits FGF/FGFR-mediated oncogenic signaling and tumor progression
Qianjin Li, O. Alsaidan, Yong-Jie Ma, Sungjin Kim +8 more
2018Journal of Biological Chemistry23 citations Open access
Semantic Scholar
The Lectin-like Domain of TNF Increases ENaC Open Probability through a Novel Site at the Interface between the Second Transmembrane and C-terminal Domains of the α-Subunit*
R. Lucas, Q. Yue, A. Alli, B. Duke +16 more
2016Journal of Biological Chemistry22 citations Open access
Semantic Scholar
Multi-kinase inhibitors interact with sildenafil and ERBB1/2/4 inhibitors to kill tumor cells in vitro and in vivo
Laurence A. Booth, T. Albers, Jane L. Roberts, M. Tavallai +3 more
2016OncoTarget22 citations Open access
Semantic Scholar
Changes in the tumor microenvironment and outcome for TME-targeting therapy in glioblastoma: A pilot study
S. Ali, T. Borin, R. Piranlioglu, Roxan Ara +5 more
2021PLoS ONE20 citations Open access
Semantic Scholar
Ternary Condensation of Biginelli Thiones, Chloroacetic Acid, and Aldehydes as an Effective Approach towards Thiazolo[3,2-a] pyrimidines and 5-Arylidenethiazolidine-2,4-diones
Iryna Lebedyeva, Mykhaylo V. Povstyanoy, A. Ryabitskii, V. Povstyanoy
201018 citations
Semantic Scholar
The Thorpe–Ziegler-type reaction of 3-cyanopyridine-2(1H)-thiones with Biginelli 6-bromomethyl-3,4-dihydropyrimidin-2(1H)-ones: cascade assembling of tetra- and pentacyclic heterocyclic scaffolds
Iryna Lebedyeva, V. Dotsenko, Vladimir V. Turovtsev, S. Krivokolysko +2 more
201214 citations
Semantic Scholar
Gabapentin hybrid peptides and bioconjugates.
Iryna Lebedyeva, D. Ostrov, J. Neubert, P. Steel +6 more
2014Bioorganic & Medicinal Chemistry12 citations
Semantic Scholar
Tandem deprotection-dimerization-macrocyclization route to C(2) symmetric cyclo-tetrapeptides.
Khanh Q. Ha, Iryna Lebedyeva, S. Hamedzadeh, Zhi-Liang Li +7 more
2014Chemistry11 citations
Semantic Scholar
Synthesis of taurine-containing peptides, sulfonopeptides, and N- and O-conjugates.
Peter Vertesaljai, Suvendu Biswas, Iryna Lebedyeva, E. Broggi +2 more
2014Journal of Organic Chemistry9 citations
Semantic Scholar
A benzotriazole-mediated route to protected marine-derived hetero-2,5-diketopiperazines containing proline.
O. Nsengiyumva, S. Hamedzadeh, James W McDaniel, Jocelyn M Macho +8 more
2015Organic and biomolecular chemistry8 citations
Semantic Scholar
Theophyllinylpyrimidine Scaffolds Undergo Intramolecular Cyclization Reactions to Form 1,3-Diazepines and Imidazopurines
Iryna Lebedyeva, V. Povstyanoy, A. Ryabitskii, Oleksandr G. Panasyuk +5 more
20138 citations
Semantic Scholar
Conformationally assisted lactamizations for the synthesis of symmetrical and unsymmetrical bis-2,5-diketopiperazines.
Khanh Q. Ha, Iryna Lebedyeva, Zhi-Liang Li, Kristy A. Martin +6 more
2013Journal of Organic Chemistry8 citations
Semantic Scholar
Inhibition of N-Myristoyltransferase activity promotes androgen receptor degradation in prostate cancer
O. Alsaidan, Emmanuel Onobun, Chenming Ye, Lei Lou +5 more
2023The Prostate6 citations Open access
Semantic Scholar
One-pot decarboxylative acylation of N-, O-, S-nucleophiles and peptides with 2,2-disubstituted malonic acids.
Iryna Lebedyeva, Suvendu Biswas, Kevin Goncalves, Sean M. Sileno +4 more
2014Chemistry6 citations
Semantic Scholar
Benzotriazole-Based Strategies Toward Peptidomimetics, Conjugates, and Other Peptide Derivatives
T. Albers, Davita L. Watkins, A. Gameiro, V. Povstyanoy +2 more
20155 citations
Semantic Scholar
One-pot synthesis of diethyl 4,4′-(1,4-phenylene)bis[6-(halomethyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylates] and their bispyrrolocyclization
Iryna Lebedyeva, Mykhaylo V. Povstyanoy, V. Povstyanoy, Oleksandr G. Panasyuk +2 more
20105 citations
Semantic Scholar
A Non-Systemic Phosphodiesterase-5 Inhibitor Suppresses Colon Proliferation in Mice
Avelina Lee, Iryna Lebedyeva, Wen-Bo Zhi, Vani Senthil +6 more
2023International Journal of Molecular Sciences4 citations Open access
Semantic Scholar
Peptidoyl Benzotriazolide-Mediated Acylation of Nitrile-Activated Methylene Groups
Sandhyamayee Sahu, Iryna Lebedyeva, Siva S. Panda, A. Katritzky
20134 citations
Semantic Scholar
17α-Ethynylestradiol Peptide Labeling by ‘Click’ Chemistry
Oleg Bol'shakov, Iryna Lebedyeva, A. Katritzky
20124 citations
Semantic Scholar
Corrigendum to "CXCR2-Expressing Tumor Cells Drive Vascular Mimicry in Antiangiogenic Therapy-Resistant Glioblastoma" Neoplasia, October 2018, Volume 20, Issue 10, Pages 1070-1082.
Kartik Angara, T. Borin, M. Rashid, Iryna Lebedyeva +6 more
2019Neoplasia3 citations Open access
Semantic Scholar
Diazapentacene derivatives: synthesis, properties, and structures
J. J. Hoff, Lei Zhu, Yutong Dong, T. Albers +5 more
20163 citations
Semantic Scholar
Abstract 127: CYP4A11 overexpression increases aggressiveness in glioblastoma and breast cancer
T. Borin, S. Ali, Kartik Angara, M. Rashid +6 more
2019Tumor Biology2 citations Open access
Semantic Scholar
Synthesis of L‐Lys‐Aminoxy‐Goralatide
Zhi-Liang Li, Iryna Lebedyeva, De-Qian Zhao, Lauren Myers +3 more
2014Journal of Peptide Science2 citations
Semantic Scholar
Sweet-Tasting Ionic Conjugates of Local Anesthetics and Vasoconstrictors
J. Neubert, A. Oliferenko, Polina V. Oliferenko, Sergey V. Emets +6 more
2021Molecules1 citations Open access
Semantic Scholar
Influence of spatial static and dynamic inhomogeneities on the distribution of electroelastic fields and electronic processes in piezoceramic composites
Iryna Lebedyeva, O. Boryseiko, Valeriy Y. Yashchuk
20211 citations
Semantic Scholar
Changes in the tumor microenvironment and treatment outcome in glioblastoma: A pilot study
S. Ali, T. Borin, R. Piranlioglu, Roxan Ara +5 more
2020bioRxiv1 citations Open access
Semantic Scholar
Mimicking a proline tripeptide with pyrazolidines and a cyclopentane linker
Peter Vertesaljai, Iryna Lebedyeva, A. Oliferenko, Xin Qi +5 more
20151 citations
Semantic Scholar
Abstract A293: Novel allosteric small molecule FAK inhibitors effectively inhibit cancer cell viability and clonogenicity.
V. Golubovskaya, Iryna Lebedyeva, B. Ho, Michael Yemma +5 more
20131 citations
Semantic Scholar
Abstract 1417: A non-systemic phosphodiesterase-5 inhibitor for colon cancer prevention
Bianca N. Islam, Avelina Lee, Iryna Lebedyeva, D. Browning
2022Cancer Research0 citations
Semantic Scholar
Variations of morphology of fluoropolymer thin films versus deposition conditions
K. Grytsenko, Y. Kolomzarov, P. Lytvyn, Iryna Lebedyeva +1 more
2021Surface Topography Metrology and Properties0 citations
Semantic Scholar
Conjugation of Tryptamine to Biologically Active Carboxylic Acids in Order to Create Prodrugs
C. Miller, Iryna Lebedyeva
2021The Arsenal: The Undergraduate Research Journal of Augusta University0 citations Open access
Semantic Scholar
Neutral ceramidase regulates ferroptosis in myeloid-derived suppressor cells
Huabin Zhu, Chun-Wan Lu, Da-Feng Yang, Priscilla S. Redd +8 more
2020Journal of Immunology0 citations
Semantic Scholar
Abstract A32: The SUV39H1-H3K9me3 pathway represses cytotoxic T lymphocyte effector expression to confer colon carcinoma immune escape
Chun-Wan Lu, Da-Feng Yang, John D. Klement, Kyu Oh +13 more
20200 citations
Semantic Scholar
Abstract 2263: Ceramide mimetics regulation of tumor cell response to immune checkpoint inhibitor immunotherapy
Priscilla S. Redd, Chun-Wan Lu, John D. Klement, Mohammed L. Ibrahim +4 more
2019Immunology0 citations
Semantic Scholar
Abstract 4966: The SUV39H1-H3K9me3 axis mediates colon carcinoma cell intrinsic apoptosis and immune evasion
Chun-Wan Lu, Da-Feng Yang, John D. Klement, A. Colby +6 more
2018Immunology0 citations
Semantic Scholar
Abstract 1679: Interference of PD-1 and PD-L1 interaction with small-molecule inhibitors enhances the efficacy of tumor-specific CTLs
Priscilla S. Redd, Chun-Wan Lu, D. Ostrov, Iryna Lebedyeva +1 more
2018Immunology0 citations
Semantic Scholar
SYNTHESIS OF PEPTIDES WITH FLUORESCENT TAGS
Angel M. Weather, Zachary Sweatman, Junsoo Bae, Iryna Lebedyeva
20180 citations
Semantic Scholar
Functionalized Diphenyl‐Imidazolo‐Pyrimidines
Pavel P. Lyubashov, V. Povstyanoy, A. A. Krysko, A. Plotkin +3 more
20180 citations
Semantic Scholar
Abstract A070: Targeting N-myristoyltransferase 1 inhibits prostate cancer progression
O. Alsaidan, Sungjin Kim, O. Goodwin, Qianjin Li +8 more
2018Poster Presentations - Proffered Abstracts0 citations
Semantic Scholar

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