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Da-Feng Yang · SciRah

Researcher profile · Semantic Scholar

Da-Feng Yang

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Da-Feng Yang — researcher profile on SciRah

h-index: 36
Works: 99
Citations: 3,159

Most-cited papers

An osteopontin/CD44 immune checkpoint controls CD8+ T cell activation and tumor immune evasion
John D. Klement, A. Paschall, Priscilla S. Redd, Mohammed L. Ibrahim +6 more
2018Journal of Clinical Investigation302 citations Open access
Semantic Scholar
NF-κB Directly Regulates Fas Transcription to Modulate Fas-mediated Apoptosis and Tumor Suppression*
Fei-Yan Liu, Kankana Bardhan, Da-Feng Yang, M. Thangaraju +5 more
2012Journal of Biological Chemistry131 citations Open access
Semantic Scholar
Long noncoding RNA SNHG12 integrates a DNA-PK–mediated DNA damage response and vascular senescence
S. Haemmig, Da-Feng Yang, Xinghui Sun, Debapria Das +19 more
2020Science Translational Medicine120 citations Open access
Semantic Scholar
Asah2 represses the p53-Hmox1 axis to protect myeloid-derived suppressor cells from ferroptosis
Huabin Zhu, John D. Klement, Chun-Wan Lu, Priscilla S. Redd +12 more
2021Journal of Immunology117 citations Open access
Semantic Scholar
Tumor PD-L1 engages myeloid PD-1 to suppress type I interferon to impair cytotoxic T lymphocyte recruitment
John D. Klement, Priscilla S. Redd, Chun-Wan Lu, Alyssa D Merting +7 more
2023Cancer Cell108 citations Open access
Semantic Scholar
H3K9 Trimethylation Silences Fas Expression to Confer Colon Carcinoma Immune Escape and 5-Fluorouracil Chemoresistance
A. Paschall, Da-Feng Yang, Chun-Wan Lu, Jeong-Hyeon Choi +8 more
2015Journal of Immunology102 citations Open access
Semantic Scholar
Repression of IFN regulatory factor 8 by DNA methylation is a molecular determinant of apoptotic resistance and metastatic phenotype in metastatic tumor cells.
Da-Feng Yang, M. Thangaraju, Kristy M. Greeneltch, D. Browning +6 more
2007Cancer Research93 citations Open access
Semantic Scholar
Decitabine and Vorinostat Cooperate to Sensitize Colon Carcinoma Cell to FasL-induced Apoptosis In Vitro and Tumor Suppression In Vivo
Da-Feng Yang, Christina M. Torres, Kankana Bardhan, Mary A. Zimmerman +2 more
2012Journal of Immunology90 citations Open access
Semantic Scholar
Myeloid-Derived Suppressor Cells Produce IL-10 to Elicit DNMT3b-Dependent IRF8 Silencing to Promote Colitis-Associated Colon Tumorigenesis
Mohammed L. Ibrahim, John D. Klement, Chun-Wan Lu, Priscilla S. Redd +7 more
2018Cell Reports87 citations Open access
Semantic Scholar
WDR5-H3K4me3 epigenetic axis regulates OPN expression to compensate PD-L1 function to promote pancreatic cancer immune escape
Chun-Wan Lu, Zhuo-Qi Liu, John D. Klement, Da-Feng Yang +6 more
2021Journal for ImmunoTherapy of Cancer85 citations Open access
Semantic Scholar
Long Noncoding RNAs in Cardiovascular Pathology, Diagnosis, and Therapy
S. Haemmig, Viorel Simion, Da-Feng Yang, Yihuan Deng +1 more
2017Current Opinion in Cardiology85 citations Open access
Semantic Scholar
Deregulation of Apoptotic Factors Bcl-xL and Bax Confers Apoptotic Resistance to Myeloid-derived Suppressor Cells and Contributes to Their Persistence in Cancer*
Xiao-Ling Hu, Kankana Bardhan, A. Paschall, Da-Feng Yang +6 more
2013Journal of Biological Chemistry70 citations Open access
Semantic Scholar
IRF8 Regulates Acid Ceramidase Expression to Mediate Apoptosis and Suppresses Myelogeneous Leukemia
Xiao-Ling Hu, Da-Feng Yang, Mary A. Zimmerman, Fei-Yan Liu +8 more
2011Cancer Research69 citations Open access
Semantic Scholar
Autocrine IL6-mediated activation of the STAT3-DNMT axis silences the TNFα-RIP1 necroptosis pathway to sustain survival and accumulation of myeloid-derived suppressor cells
Alyssa D. Smith, Chun-Wan Lu, Daniela Payne, A. Paschall +10 more
2020Cancer Research68 citations Open access
Semantic Scholar
LncRNA VINAS regulates atherosclerosis by modulating NF-κB and MAPK signaling
Viorel Simion, Haoyang Zhou, Jacob B. Pierce, Da-Feng Yang +6 more
2020JCI Insight66 citations Open access
Semantic Scholar
The NF-κB p65 and p50 homodimer cooperate with IRF8 to activate iNOS transcription
Priscilla S. Simon, Sarah K. Sharman, Chun-Wan Lu, Da-Feng Yang +3 more
2015BMC Cancer66 citations Open access
Semantic Scholar
Adipocytes promote interleukin-18 binding to its receptors during abdominal aortic aneurysm formation in mice.
Cong-Lin Liu, Jingyuan Ren, Yun-Zhe Wang, Xian Zhang +14 more
2019European Heart Journal62 citations Open access
Semantic Scholar
SETD1B activates iNOS expression in myeloid-derived suppressor cells
Priscilla S. Redd, Mohammed L. Ibrahim, John D. Klement, Sarah K. Sharman +4 more
2017Cancer Research61 citations Open access
Semantic Scholar
DNA Methylation Represses IFN-γ–Induced and Signal Transducer and Activator of Transcription 1–Mediated IFN Regulatory Factor 8 Activation in Colon Carcinoma Cells
Jon M McGough, Da-Feng Yang, Shuang Huang, David E. Georgi +5 more
2008Molecular Cancer Research58 citations Open access
Semantic Scholar
SUV39H1 represses the expression of cytotoxic T-lymphocyte effector genes to promote colon tumor immune evasion
Chun-Wan Lu, Da-Feng Yang, John D. Klement, Kyu Oh +13 more
2019Cancer immunology research57 citations Open access
Semantic Scholar
Verticillin A Overcomes Apoptosis Resistance in Human Colon Carcinoma through DNA methylation-dependent Upregulation of BNIP3
Fei-Yan Liu, Qianqian Liu, Da-Feng Yang, W. Bollag +3 more
2011Cancer Research54 citations Open access
Semantic Scholar
Contrasting roles of H3K4me3 and H3K9me3 in regulation of apoptosis and gemcitabine resistance in human pancreatic cancer cells
Chun-Wan Lu, Da-Feng Yang, M. Sabbatini, A. Colby +4 more
2018BMC Cancer53 citations Open access
Semantic Scholar
Dihydromyricetin increases endothelial nitric oxide production and inhibits atherosclerosis through microRNA‐21 in apolipoprotein E‐deficient mice
Da-Feng Yang, Zhou-Sheng Yang, Lei Chen, Dabin Kuang +14 more
2020Journal of Cellular and Molecular Medicine52 citations Open access
Semantic Scholar
Regulation of Fas Expression in Nonhemopoietic Tumor Cells via IFN Regulatory Factor 8 Mediates Apoptosis
Da-Feng Yang, M. Thangaraju, D. Browning, Zheng Dong +4 more
200751 citations
Semantic Scholar
Unphosphorylated STAT1 promotes sarcoma development through repressing expression of Fas and Bad and conferring apoptotic resistance
Mary A. Zimmerman, Nur-Taz Rahman, Da-Feng Yang, G. Lahat +4 more
2012Cancer Research50 citations Open access
Semantic Scholar
Osteopontin Blockade Immunotherapy Increases Cytotoxic T Lymphocyte Lytic Activity and Suppresses Colon Tumor Progression
John D. Klement, Dakota B Poschel, Chun-Wan Lu, Alyssa D Merting +3 more
2021Cancers49 citations Open access
Semantic Scholar
The diagnostic value of circulating microRNAs for middle-aged (40–60-year-old) coronary artery disease patients
Ali Sheikh Md Sayed, K. Xia, Fei Li, Xu Deng +7 more
2015Clinics49 citations Open access
Semantic Scholar
A smooth muscle cell-enriched lncRNA regulates cell plasticity and atherosclerosis by interacting with serum response factor
Huaner Ni, S. Haemmig, Yihuan Deng, Jing-Shu Chen +12 more
2021Arteriosclerosis, Thrombosis and Vascular Biology47 citations Open access
Semantic Scholar
Ceramide targets xIAP and cIAP1 to sensitize metastatic colon and breast cancer cells to apoptosis induction to suppress tumor progression
A. Paschall, Mary A. Zimmerman, Christina M. Torres, Da-Feng Yang +7 more
2014BMC Cancer46 citations Open access
Semantic Scholar
MicroRNA‐181b inhibits thrombin‐mediated endothelial activation and arterial thrombosis by targeting caspase recruitment domain family member 10
Jibin Lin, Shao-Lin He, Xinghui Sun, G. Franck +7 more
2016The FASEB Journal44 citations Open access
Semantic Scholar
SUV39H1 regulates human colon carcinoma apoptosis and cell cycle to promote tumor growth
Chun-Wan Lu, John D. Klement, Da-Feng Yang, T. Albers +3 more
2020Cancer Letters41 citations Open access
Semantic Scholar
IFNγ induces DNA methylation-silenced GPR109A expression via pSTAT1/p300 and H3K18 acetylation in colon cancer
Kankana Bardhan, A. Paschall, Da-Feng Yang, May R. Chen +10 more
2015Cancer immunology research40 citations Open access
Semantic Scholar
Loss of Fas Expression and Function is Coupled with Colon Cancer Resistance to Immune Checkpoint Inhibitor Immunotherapy
Wei-Ling Xiao, Mohammed L. Ibrahim, Priscilla S. Redd, John D. Klement +4 more
2018Molecular Cancer Research39 citations Open access
Semantic Scholar
CD133+CD24lo defines a 5-Fluorouracil-resistant colon cancer stem cell-like phenotype
A. Paschall, Da-Feng Yang, Chun-Wan Lu, Priscilla S. Redd +5 more
2016OncoTarget39 citations Open access
Semantic Scholar
CTL Adoptive Immunotherapy Concurrently Mediates Tumor Regression and Tumor Escape
Ke-Bin Liu, Sheila Caldwell, Kristy M. Greeneltch, Da-Feng Yang +1 more
2006Journal of Immunology39 citations Open access
Semantic Scholar
Lipid nanoparticle delivery of Fas plasmid restores Fas expression to suppress melanoma growth in vivo
Zeinab Y. Al Subeh, Dakota B Poschel, Priscilla S. Redd, John D. Klement +10 more
2022ACS Nano36 citations Open access
Semantic Scholar
IFN Regulatory Factor 8 Sensitizes Soft Tissue Sarcoma Cells to Death Receptor-initiated Apoptosis via Repression of FLICE-like Protein Expression
Da-Feng Yang, Sui-Zhao Wang, C. Brooks, Zheng Dong +10 more
2009Cancer Research36 citations Open access
Semantic Scholar
G6PD functions as a metabolic checkpoint to regulate granzyme B expression in tumor-specific cytotoxic T lymphocytes
Chun-Wan Lu, Da-Feng Yang, John D. Klement, Y. Colson +7 more
2022Journal for ImmunoTherapy of Cancer34 citations Open access
Semantic Scholar
Lymphotoxin β receptor mediates caspase-dependent tumor cell apoptosis in vitro and tumor suppression in vivo despite induction of NF-κB activation.
Xiao-Ling Hu, Mary A. Zimmerman, Kankana Bardhan, Da-Feng Yang +10 more
2013Carcinogenesis34 citations Open access
Semantic Scholar
IFN-γ Upregulates Survivin and Ifi202 Expression to Induce Survival and Proliferation of Tumor-Specific T Cells
Mary A. Zimmerman, Da-Feng Yang, Xiao-Ling Hu, Fei-Yan Liu +7 more
2010PLoS ONE34 citations Open access
Semantic Scholar
Downregulation of IFN‐γR in association with loss of Fas function is linked to tumor progression
Da-Feng Yang, T. Stewart, Kimberly K. Smith, David E. Georgi +2 more
2008International Journal of Cancer33 citations Open access
Semantic Scholar
Cutting Edge: IRF8 Regulates Bax Transcription In Vivo in Primary Myeloid Cells
Jine Yang, Xiao-Ling Hu, Mary A. Zimmerman, Christina M. Torres +3 more
2011Journal of Immunology30 citations Open access
Semantic Scholar
H3K9me3 represses G6PD expression to suppress the pentose phosphate pathway and ROS production to promote human mesothelioma growth
Chun-Wan Lu, Da-Feng Yang, John D. Klement, Y. Colson +8 more
2022Oncogene27 citations Open access
Semantic Scholar
Dihydromyricetin Attenuates TNF-α-Induced Endothelial Dysfunction through miR-21-Mediated DDAH1/ADMA/NO Signal Pathway
Da-Feng Yang, Sheng-Lan Tan, Zhou-Sheng Yang, Pei Jiang +10 more
2018BioMed Research International27 citations Open access
Semantic Scholar
Targeting Lymphotoxin β Receptor with Tumor-Specific T Lymphocytes for Tumor Regression
Da-Feng Yang, Najam ud din, D. Browning, S. Abrams +1 more
2007Clinical Cancer Research26 citations Open access
Semantic Scholar
Downregulation of Profilin-1 Expression Attenuates Cardiomyocytes Hypertrophy and Apoptosis Induced by Advanced Glycation End Products in H9c2 Cells
Da-Feng Yang, Ya Wang, M. Jiang, Xu Deng +6 more
2017BioMed Research International25 citations Open access
Semantic Scholar
Eosinophils protect pressure overload- and β-adrenoreceptor agonist-induced cardiac hypertrophy
Chong-Zhe Yang, Jie Li, Zhiyong Deng, Songyuan Luo +19 more
2022Cardiovascular Research24 citations Open access
Semantic Scholar
Methotrexate attenuates vascular inflammation through an adenosine-microRNA-dependent pathway
Da-Feng Yang, S. Haemmig, Haoyang Zhou, D. Pérez-Cremades +7 more
2021eLife24 citations Open access
Semantic Scholar
Regulatory T cells promote adipocyte beiging in subcutaneous adipose tissue
Wenqian Fang, Zhiyong Deng, Feriel Benadjaoud, Da-Feng Yang +2 more
2020The FASEB Journal24 citations Open access
Semantic Scholar
Biosilicate scaffolds for bone regeneration: influence of introducing SrO
Ci-Jun Shuai, Hang Sun, Ping Wu, Cheng-De Gao +6 more
201723 citations Open access
Semantic Scholar

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