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L. Goff · SciRah

Researcher profile · Semantic Scholar

L. Goff

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L. Goff — researcher profile on SciRah

h-index: 43
Works: 111
Citations: 27K

Most-cited papers

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks
C. Trapnell, Adam Roberts, L. Goff, G. Pertea +6 more
2012Nature Protocols12K citations Open access
Semantic Scholar
Differential analysis of gene regulation at transcript resolution with RNA-seq
C. Trapnell, David G. Hendrickson, Martin Sauvageau, L. Goff +2 more
2012Nature Biotechnology3,569 citations Open access
Semantic Scholar
Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses.
M. Cabili, C. Trapnell, L. Goff, Magdalena J. Koziol +3 more
2011Genes & Development3,402 citations Open access
Semantic Scholar
Multiple knockout mouse models reveal lincRNAs are required for life and brain development
Martin Sauvageau, L. Goff, Simona Lodato, B. Bonev +21 more
2013eLife681 citations Open access
Semantic Scholar
Topological Organization of Multi-chromosomal Regions by Firre
Ezgi Hacisuleyman, L. Goff, C. Trapnell, Adam Williams +14 more
2014Nature Structural &Molecular Biology598 citations Open access
Semantic Scholar
DNMT1-interacting RNAs block gene specific DNA methylation
A. Di Ruscio, A. Ebralidze, T. Benoukraf, G. Amabile +14 more
2013Nature508 citations Open access
Semantic Scholar
Single cell RNA-Seq analysis of retinal development identifies NFI factors as regulating mitotic exit and late-born cell specification.
Brian S. Clark, G. Stein-O'Brien, Fion Shiau, Gabrielle H. Cannon +10 more
2019Neuron409 citations Open access
Semantic Scholar
Long noncoding RNAs regulate adipogenesis
Lei Sun, L. Goff, C. Trapnell, Ryan K. Alexander +10 more
2013Proceedings of the National Academy of Sciences of the United States of America408 citations Open access
Semantic Scholar
Psychedelics reopen the social reward learning critical period
Romain Nardou, E. Sawyer, Young-Ju Song, Makenzie Wilkinson +8 more
2023Nature307 citations Open access
Semantic Scholar
The microRNA miR-181 is a critical cellular metabolic rheostat essential for NKT cell ontogenesis and lymphocyte development and homeostasis
Jorge Henao-Mejia, Adam Williams, L. Goff, Matthew M. Staron +5 more
2013Immunity269 citations Open access
Semantic Scholar
Single-Cell Analysis of Human Retina Identifies Evolutionarily Conserved and Species-Specific Mechanisms Controlling Development
Yufeng Lu, Fion Shiau, Wenyang Yi, Suying Lu +24 more
2019bioRxiv254 citations Open access
Semantic Scholar
DeCoN: genome-wide analysis of in vivo transcriptional dynamics during pyramidal neuron fate selection in neocortex
B. Molyneaux, L. Goff, Andrea C. Brettler, Hsu-Hsin Chen +4 more
2014Neuron236 citations Open access
Semantic Scholar
Enter the Matrix: Factorization Uncovers Knowledge from Omics
G. Stein-O'Brien, R. Arora, A. Culhane, Alexander V. Favorov +8 more
2018Trends in Genetics231 citations Open access
Semantic Scholar
Transcriptional and epigenomic landscapes of CNS and non-CNS vascular endothelial cells
Mark F. Sabbagh, Jacob S. Heng, C. Luo, R. Castanon +5 more
2018eLife214 citations Open access
Semantic Scholar
Linking RNA biology to lncRNAs
L. Goff, J. Rinn
2015Genome Research171 citations Open access
Semantic Scholar
Spatiotemporal expression and transcriptional perturbations by long noncoding RNAs in the mouse brain
L. Goff, A. Groff, Martin Sauvageau, Zachary Trayes-Gibson +12 more
2015Proceedings of the National Academy of Sciences of the United States of America155 citations Open access
Semantic Scholar
Linear models enable powerful differential activity analysis in massively parallel reporter assays
Leslie Myint, D. Avramopoulos, L. Goff, K. Hansen
2017BMC Genomics140 citations Open access
Semantic Scholar
Gene co-regulation by Fezf2 selects neurotransmitter identity and connectivity of corticospinal neurons
Simona Lodato, B. Molyneaux, Emanuela Zuccaro, L. Goff +8 more
2014Nature Neuroscience137 citations Open access
Semantic Scholar
A ketogenic diet rescues hippocampal memory defects in a mouse model of Kabuki syndrome
J. Benjamin, Genay O. Pilarowski, Giovanni A. Carosso, Li Zhang +5 more
2016Proceedings of the National Academy of Sciences of the United States of America117 citations Open access
Semantic Scholar
Prenatal immune stress blunts microglia reactivity, impairing neurocircuitry
L. Hayes, K. An, E. Carloni, Fangze Li +8 more
2022Nature114 citations Open access
Semantic Scholar
Universal prediction of cell-cycle position using transfer learning
Shijie C. Zheng, G. Stein-O’Brien, Jonathan J Augustin, Jared Slosberg +6 more
2021Genome Biology111 citations Open access
Semantic Scholar
Erratum: Live imaging and quantitative analysis of gastrulation in mouse embryos using light-sheet microscopy and 3D tracking tools
C. Trapnell, Adam Roberts, L. Goff, G. Pertea +6 more
2014Nature Protocols111 citations Open access
Semantic Scholar
The long non-coding RNAs : a new ( p ) layer in the “ dark matter ”
Martin Sauvageau, L. Goff, Simona Lodato, B. Bonev +21 more
2014109 citations
Semantic Scholar
Decomposing cell identity for transfer learning across cellular measurements, platforms, tissues, and species
G. Stein-O'Brien, Brian S. Clark, Thomas Sherman, Cristina Zibetti +8 more
2019Cell Systems99 citations Open access
Semantic Scholar
Changes in the Excitability of Neocortical Neurons in a Mouse Model of Amyotrophic Lateral Sclerosis Are Not Specific to Corticospinal Neurons and Are Modulated by Advancing Disease
Juhyun Kim, E. Hughes, Ashwin S. Shetty, P. Arlotta +3 more
2017Journal of Neuroscience91 citations Open access
Semantic Scholar
RNase-mediated protein footprint sequencing reveals protein-binding sites throughout the human transcriptome
I. Silverman, Fan Li, Anissa Alexander, L. Goff +3 more
2014Genome Biology90 citations Open access
Semantic Scholar
Expression profiling of synaptic microRNAs from the adult rat brain identifies regional differences and seizure-induced dynamic modulation
Israel Pichardo-Casas, L. Goff, M. Swerdel, Alejandro Athie +6 more
2011Brain Research86 citations Open access
Semantic Scholar
Decomposing cell identity for transfer learning across cellular measurements, platforms, tissues, and species
G. Stein-O'Brien, Brian S. Clark, Thomas Sherman, Cristina Zibetti +8 more
2018bioRxiv82 citations Open access
Semantic Scholar
projectR: An R/Bioconductor package for transfer learning via PCA, NMF, correlation, and clustering
Gaurav Sharma, C. Colantuoni, L. Goff, E. Fertig +1 more
2019bioRxiv77 citations Open access
Semantic Scholar
Variation in Activity State, Axonal Projection, and Position Define the Transcriptional Identity of Individual Neocortical Projection Neurons
Maxime Chevée, Johanna De Jong Robertson, Gabrielle H. Cannon, S. Brown +1 more
2018Cell Reports76 citations Open access
Semantic Scholar
Comprehensive analysis of a mouse model of spontaneous uveoretinitis using single-cell RNA sequencing
Jacob S. Heng, S. Hackett, Genevieve Stein-O'Brien, B. Winer +3 more
2019Proceedings of the National Academy of Sciences of the United States of America72 citations Open access
Semantic Scholar
Parallel social information processing circuits are differentially impacted in autism
Eastman M. Lewis, G. Stein-O'Brien, Alejandra V. Patino, Romain Nardou +9 more
2020bioRxiv70 citations Open access
Semantic Scholar
Hypoxia tolerance in the Norrin-deficient retina and the chronically hypoxic brain studied at single-cell resolution
Jacob S. Heng, A. Rattner, Genevieve Stein-O'Brien, B. Winer +4 more
2019Proceedings of the National Academy of Sciences of the United States of America70 citations Open access
Semantic Scholar
Group 1 Innate lymphoid cell lineage identity is determined by a cis-regulatory element marked by a long non-coding RNA
Walter K. Mowel, S. McCright, Jonathan J. Kotzin, Magalie A. Collet +24 more
2017Immunity69 citations Open access
Semantic Scholar
Computational Analysis of Noncoding RNAs
Stefan Washietl, S. Will, D. Hendrix, L. Goff +3 more
2012Wiley Interdisciplinary Reviews - RNA60 citations Open access
Semantic Scholar
Precocious neuronal differentiation and disrupted oxygen responses in Kabuki syndrome.
Giovanni A. Carosso, Leandros Boukas, Jonathan J Augustin, Ha Nam Nguyen +7 more
2019JCI Insight51 citations Open access
Semantic Scholar
Keratinocyte-derived defensins activate neutrophil-specific receptors Mrgpra2a/b to prevent skin dysbiosis and bacterial infection
Xin-Tong Dong, N. Limjunyawong, Elizabeth I. Sypek, Gaofeng Wang +16 more
2022Immunity49 citations Open access
Semantic Scholar
Follistatin promotes LIN28B-mediated supporting cell reprogramming and hair cell regeneration in the murine cochlea
Xiao-Jun Li, Charles Morgan, L. Goff, Angelika Doetzlhofer
2022Science Advances45 citations Open access
Semantic Scholar
Creation and characterization of an airway epithelial cell line for stable expression of CFTR variants
Laura B Gottschalk, B. Vecchio-Pagan, N. Sharma, Sangwoo T. Han +5 more
2015Journal of Cystic Fibrosis40 citations Open access
Semantic Scholar
Mitoregulin Controls β-Oxidation in Human and Mouse Adipocytes
M. Friesen, C. R. Warren, Hao-Jie Yu, T. Toyohara +7 more
2020Stem Cell Reports39 citations Open access
Semantic Scholar
A screen of 1,049 schizophrenia and 30 Alzheimer’s-associated variants for regulatory potential
Leslie Myint, Ruihua Wang, Leandros Boukas, K. Hansen +2 more
2019American Journal of Medical Genetics Part B: Neuropsychiatric Genetics39 citations Open access
Semantic Scholar
Pumping the brakes on RNA velocity – understanding and interpreting RNA velocity estimates
Shijie C. Zheng, G. Stein-O'Brien, Leandros Boukas, L. Goff +1 more
2022bioRxiv38 citations Open access
Semantic Scholar
Increased expression of anion transporter SLC26A9 delays diabetes onset in cystic fibrosis.
Anh Lam, M. Aksit, B. Vecchio-Pagan, Celeste A. Shelton +6 more
2019Journal of Clinical Investigation38 citations Open access
Semantic Scholar
The DPYSL2 gene connects mTOR and schizophrenia
X. Phạm, Guang Song, S. Lao, L. Goff +3 more
2016Translational Psychiatry38 citations Open access
Semantic Scholar
Pumping the brakes on RNA velocity by understanding and interpreting RNA velocity estimates
Shijie C. Zheng, G. Stein-O’Brien, Leandros Boukas, L. Goff +1 more
2023Genome Biology36 citations Open access
Semantic Scholar
Differential variation analysis enables detection of tumor heterogeneity using single-cell RNA-sequencing data
Emily F. Davis-Marcisak, Thomas Sherman, Pranay Orugunta, G. Stein-O'Brien +8 more
2019Cancer Research33 citations Open access
Semantic Scholar
Normal and Sjogren’s syndrome models of the murine lacrimal gland studied at single-cell resolution
A. Rattner, Jacob S. Heng, B. Winer, L. Goff +1 more
2023Proceedings of the National Academy of Sciences of the United States of America31 citations Open access
Semantic Scholar
A Positive Feedback Mechanism That Regulates Expression of miR-9 during Neurogenesis
J. Davila, L. Goff, Christopher L. Ricupero, C. Camarillo +5 more
2014PLoS ONE28 citations Open access
Semantic Scholar
The Transcription Factor Tbx5 Regulates Direction-Selective Retinal Ganglion Cell Development and Image Stabilization
Timour Al-Khindi, M. Sherman, T. Kodama, P. Gopal +6 more
2022Current Biology27 citations Open access
Semantic Scholar
Investigating long noncoding RNAs using animal models.
Michael J. Feyder, L. Goff
2016Journal of Clinical Investigation26 citations Open access
Semantic Scholar

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J. Rinn×18
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J. Rinn — researcher profile on SciRah
G. Stein-O'Brien×9
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C. Trapnell×7
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E. Fertig×7
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Martin Sauvageau

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