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Angelika Doetzlhofer · SciRah

Researcher profile · Semantic Scholar

Angelika Doetzlhofer

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Angelika Doetzlhofer — researcher profile on SciRah

h-index: 20
Works: 41
Citations: 2,516

Most-cited papers

Histone Deacetylase 1 Can Repress Transcription by Binding to Sp1
Angelika Doetzlhofer, H. Rotheneder, Gerda Lagger, Manfred Koranda +4 more
1999Molecular and Cellular Biology437 citations Open access
Semantic Scholar
Mammalian cochlear supporting cells can divide and trans-differentiate into hair cells
Patricia M. White, Angelika Doetzlhofer, Yun-Shain Lee, A. Groves +1 more
2006Nature419 citations
Semantic Scholar
Math1-driven GFP expression in the developing nervous system of transgenic mice.
E. Lumpkin, Tandi Collisson, Preeti B. Parab, Adil Omer-Abdalla +7 more
2003Gene Expression Patterns284 citations
Semantic Scholar
Hey2 regulation by FGF provides a Notch-independent mechanism for maintaining pillar cell fate in the organ of Corti
Angelika Doetzlhofer, Martin L. Basch, T. Ohyama, M. Gessler +2 more
2009Developmental Cell253 citations Open access
Semantic Scholar
The Tumor Suppressor p53 and Histone Deacetylase 1 Are Antagonistic Regulators of the Cyclin-Dependent Kinase Inhibitor p21/WAF1/CIP1 Gene
Gerda Lagger, Angelika Doetzlhofer, B. Schuettengruber, Eva Haidweger +7 more
2003Molecular and Cellular Biology218 citations Open access
Semantic Scholar
p19Ink4d and p21Cip1 Collaborate to Maintain the Postmitotic State of Auditory Hair Cells, Their Codeletion Leading to DNA Damage and p53-Mediated Apoptosis
Heidi Laine, Angelika Doetzlhofer, Johanna Mantela, J. Ylikoski +4 more
2007Journal of Neuroscience96 citations Open access
Semantic Scholar
In vitro growth and differentiation of mammalian sensory hair cell progenitors: a requirement for EGF and periotic mesenchyme.
Angelika Doetzlhofer, Patricia M. White, Jane E. Johnson, Neil Segil +1 more
2004Developmental Biology93 citations Open access
Semantic Scholar
Notch Signaling Limits Supporting Cell Plasticity in the Hair Cell-Damaged Early Postnatal Murine Cochlea
Soumya Korrapati, I. Roux, Elisabeth Glowatzki, Angelika Doetzlhofer
2013PLoS ONE89 citations Open access
Semantic Scholar
Impaired neurogenesis alters brain biomechanics in a neuroprogenitor-based genetic subtype of congenital hydrocephalus
Phan Q. Duy, S. Weise, Claudia Marini, Xiao-Jun Li +63 more
2022Nature Neuroscience86 citations Open access
Semantic Scholar
Fine-tuning of Notch signaling sets the boundary of the organ of Corti and establishes sensory cell fates
Martin L. Basch, Rogers M. Brown, Hsin-I Jen, F. Semerci +10 more
2016eLife76 citations Open access
Semantic Scholar
LIN28B/let-7 control the ability of neonatal murine auditory supporting cells to generate hair cells through mTOR signaling
Xiao-Jun Li, Angelika Doetzlhofer
2020Proceedings of the National Academy of Sciences of the United States of America62 citations Open access
Semantic Scholar
Hey1 and Hey2 Control the Spatial and Temporal Pattern of Mammalian Auditory Hair Cell Differentiation Downstream of Hedgehog Signaling
Ana Benito-Gonzalez, Angelika Doetzlhofer
2014Journal of Neuroscience59 citations Open access
Semantic Scholar
The RNA-binding protein LIN28B regulates developmental timing in the mammalian cochlea
E. Golden, Ana Benito-Gonzalez, Angelika Doetzlhofer
2015Proceedings of the National Academy of Sciences of the United States of America47 citations Open access
Semantic Scholar
Follistatin promotes LIN28B-mediated supporting cell reprogramming and hair cell regeneration in the murine cochlea
Xiao-Jun Li, Charles Morgan, L. Goff, Angelika Doetzlhofer
2022Science Advances45 citations Open access
Semantic Scholar
Alternate Activation of Two Divergently Transcribed Mouse Genes from a Bidirectional Promoter Is Linked to Changes in Histone Modification* 210
B. Schuettengruber, Angelika Doetzlhofer, K. Kroboth, E. Wintersberger +1 more
2003Journal of Biological Chemistry34 citations Open access
Semantic Scholar
Prospective identification and purification of hair cell and supporting cell progenitors from the embryonic cochlea.
Angelika Doetzlhofer, Patricia M. White, Yun-Shain Lee, A. Groves +1 more
2006Brain Research33 citations
Semantic Scholar
Canonical Notch signaling plays an instructive role in auditory supporting cell development
Dean P. Campbell, Elena Chrysostomou, Angelika Doetzlhofer
2016Scientific Reports28 citations Open access
Semantic Scholar
Growth-regulated antisense transcription of the mouse thymidine kinase gene.
Hedwig Sutterluety, Stefan Bartl, Angelika Doetzlhofer, Harald Khier +2 more
1998Nucleic Acids Research26 citations Open access
Semantic Scholar
A counter gradient of Activin A and follistatin instructs the timing of hair cell differentiation in the murine cochlea
Meenakshi Prajapati-DiNubila, Ana Benito-Gonzalez, E. Golden, Shuran Zhang +1 more
2019eLife24 citations Open access
Semantic Scholar
Seminars in Cell and Developmental Biology Insights into inner ear-specific gene regulation: epigenetics and non-coding RNAs in inner ear development and regeneration
Angelika Doetzlhofer
201623 citations
Semantic Scholar
let-7 miRNAs inhibit CHD7 expression and control auditory-sensory progenitor cell behavior in the developing inner ear
Lale Evsen, Xiao-Jun Li, Shuran Zhang, S. Razin +1 more
2020Development18 citations Open access
Semantic Scholar
The Notch Ligand Jagged1 Is Required for the Formation, Maintenance, and Survival of Hensen's Cells in the Mouse Cochlea
Elena Chrysostomou, Luyi Zhou, Yuanzhao L. Darcy, Kaley A. Graves +2 more
2020Journal of Neuroscience17 citations Open access
Semantic Scholar
The Notch ligand Jagged1 plays a dual role in cochlear hair cell regeneration
Xiao-Jun Li, Charles Morgan, Lin Li, Wan-Yu Zhang +2 more
2025Nature Communications14 citations Open access
Semantic Scholar
Follistatin regulates the specification of the apical cochlea responsible for low-frequency hearing in mammals
Heiyeun Koo, Min-A Kim, Hyehyun Min, J. Hwang +7 more
2022Proceedings of the National Academy of Sciences of the United States of America12 citations Open access
Semantic Scholar
TRIM71 reactivation enhances the mitotic and hair cell–forming potential of cochlear supporting cells
Xiao-Jun Li, Charles Morgan, Prathamesh T. Nadar-Ponniah, W. Kolanus +1 more
2023EMBO Reports11 citations Open access
Semantic Scholar
The RNA-binding protein TRIM71 is essential for hearing in humans and mice and times auditory sensory organ development
Xiao-Jun Li, Charles Morgan, Phan Q. Duy, Lale Evsen +15 more
2025Proceedings of the National Academy of Sciences of the United States of America5 citations
Semantic Scholar
Gene Transfer into the Chicken Auditory Organ by In Ovo Micro-electroporation.
Lale Evsen, Angelika Doetzlhofer
2016Journal of Visualized Experiments5 citations Open access
Semantic Scholar
Insights into inner ear-specific gene regulation: epigenetics and non-coding RNAs in inner ear development and regeneration
Angelika Doetzlhofer, Karen B. Avraham
2016Seminars in Cell and Developmental Biology3 citations Open access
Semantic Scholar
Notch1 and Notch2 receptors mediate the prosensory functions of the Notch ligand Jagged1 in the mammalian cochlea
He Huang, Xiao-Jun Li, Elannah Venhaus, Angelika Doetzlhofer
2026bioRxiv0 citations Open access
Semantic Scholar
CASZ1 regulates the maturation of outer hair cells and is required for hearing in mice
Y. Nakano, E. C. Driver, Ning Hu, Braulio Peguero +9 more
2026iScience0 citations Open access
Semantic Scholar
The RNA-binding protein TRIM71 Promotes Supporting Cell Reprogramming and Hair Cell Regeneration by Activating Sall4
Lin Li, He Huang, Shi-Xiang Meng, Xing-Yu Liu +14 more
2026bioRxiv0 citations Open access
Semantic Scholar
Loss of Zbtb20 disrupts cochlear supporting cell differentiation and maturation and extends the postnatal hair cell regenerative window in mice
Charles Morgan, Z. Ur-Rehman, Angelika Doetzlhofer
2026bioRxiv0 citations Open access
Semantic Scholar
The Notch ligand Jagged1 plays a dual role in cochlear hair cell regeneration
Xiao-Jun Li, Charles Morgan, Lin Li, Wan-Yu Zhang +2 more
2025bioRxiv0 citations Open access
Semantic Scholar
CASZ1 regulates the rate at which outer hair cells mature and is required for hearing
Y. Nakano, E. C. Driver, Susan C. Wiechert, Braulio Peguero +7 more
2025bioRxiv0 citations Open access
Semantic Scholar
The RNA-binding protein TRIM71 is essential for hearing in humans and mice and regulates the timing of auditory sensory organ development
Xiao-Jun Li, Lin Li, Charles Morgan, Phan Q. Duy +15 more
2025bioRxiv0 citations
Semantic Scholar
Reactivation of the progenitor gene Trim71 enhances the mitotic and hair cell-forming potential of cochlear supporting cells
Xiao-Jun Li, Charles Morgan, Prathamesh T. Nadar-Ponniah, W. Kolanus +1 more
2023bioRxiv0 citations Open access
Semantic Scholar
LIN28B controls the regenerative capacity of neonatal murine auditory supporting cells through activation of mTOR signaling
Xiao-Jun Li, Angelika Doetzlhofer
2020bioRxiv0 citations Open access
Semantic Scholar
Author response: A counter gradient of Activin A and follistatin instructs the timing of hair cell differentiation in the murine cochlea
Meenakshi Prajapati-DiNubila, Ana Benito-Gonzalez, E. Golden, Shuran Zhang +1 more
20190 citations Open access
Semantic Scholar
Let-7 miRNAs control auditory sensory progenitor behavior in the vertebrate inner ear
Lale Evsen, Shuran Zhang, Angelika Doetzlhofer
2019bioRxiv0 citations Open access
Semantic Scholar
Activin signaling informs the graded pattern of terminal mitosis and hair cell differentiation in the mammalian cochlea
Meenakshi Prajapati-DiNubila, Ana Benito-Gonzalez, E. Golden, Shuran Zhang +1 more
2018bioRxiv0 citations Open access
Semantic Scholar
Author response: Fine-tuning of Notch signaling sets the boundary of the organ of Corti and establishes sensory cell fates
Martin L. Basch, Rogers M. Brown, Hsin-I Jen, F. Semerci +10 more
20160 citations Open access
Semantic Scholar

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