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I. Singeç · SciRah

Researcher profile · Semantic Scholar

I. Singeç

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I. Singeç — researcher profile on SciRah

h-index: 22
Works: 58
Citations: 2,413

Most-cited papers

Murine Features of Neurogenesis in the Human Hippocampus across the Lifespan from 0 to 100 Years
R. Knoth, I. Singeç, M. Ditter, G. Pantazis +5 more
2010PLoS ONE661 citations Open access
Semantic Scholar
Defining the actual sensitivity and specificity of the neurosphere assay in stem cell biology
I. Singeç, R. Knoth, R. P. Meyer, J. Maciaczyk +4 more
2006Nature Methods388 citations
Semantic Scholar
A Versatile Polypharmacology Platform Promotes Cytoprotection and Viability of Human Pluripotent and Differentiated Cells
Yu Chen, C. Tristan, Lu Chen, V. Jovanovic +14 more
2019bioRxiv156 citations Open access
Semantic Scholar
The leading edge of stem cell therapeutics.
I. Singeç, Rahul Jandial, A. Crain, G. Nikkhah +1 more
2007Annual Review of Medicine143 citations
Semantic Scholar
A defined roadmap of radial glia and astrocyte differentiation from human pluripotent stem cells
V. Jovanovic, C. Weber, Jaroslav Slamecka, Seungmi Ryu +16 more
2023Stem Cell Reports97 citations Open access
Semantic Scholar
Bioprinted 3D outer retina barrier uncovers RPE-dependent choroidal phenotype in advanced macular degeneration
Min Jae Song, Russ Quinn, Eric Nguyen, Christopher Hampton +20 more
2021Nature Methods70 citations Open access
Semantic Scholar
Spontaneous reversal of the developmental aging of normal human cells following transcriptional reprogramming.
H. Vaziri, K. B. Chapman, A. Guigova, J. Teichroeb +13 more
2010Regenerative medicine66 citations
Semantic Scholar
Three-dimensional scaffolding to investigate neuronal derivatives of human embryonic stem cells
P. Soman, Brian T. D. Tobe, J. W. Lee, A. Winquist +4 more
2012Biomedical microdevices64 citations Open access
Semantic Scholar
Synaptic vesicle protein synaptoporin is differently expressed by subpopulations of mouse hippocampal neurons
I. Singeç, R. Knoth, M. Ditter, C. Hagemeyer +3 more
2002The Journal of comparative neurology64 citations
Semantic Scholar
Neurogranin is expressed by principal cells but not interneurons in the rodent and monkey neocortex and hippocampus
I. Singeç, R. Knoth, M. Ditter, B. Volk +1 more
2004The Journal of comparative neurology59 citations
Semantic Scholar
Developing nociceptor-selective treatments for acute and chronic pain
S. Jayakar, Jaehoon Shim, S. Jo, B. Bean +2 more
2021Science Translational Medicine56 citations Open access
Semantic Scholar
Neurogranin expression by cerebellar neurons in rodents and non‐human primates
I. Singeç, R. Knoth, M. Ditter, M. Frotscher +1 more
2003The Journal of comparative neurology53 citations Open access
Semantic Scholar
Inflammation as a matchmaker: revisiting cell fusion
I. Singeç, E. Snyder
2008Nature Cell Biology51 citations
Semantic Scholar
Robotic high-throughput biomanufacturing and functional differentiation of human pluripotent stem cells
C. Tristan, P. Ormanoglu, J. Slamecka, C. Malley +14 more
2021Stem Cell Reports48 citations Open access
Semantic Scholar
Genetic modification of neural stem cells.
Rahul Jandial, I. Singeç, C. Ames, E. Snyder
2008Molecular Therapy46 citations Open access
Semantic Scholar
Combined use of BDNF, ascorbic acid, low oxygen, and prolonged differentiation time generates tyrosine hydroxylase-expressing neurons after long-term in vitro expansion of human fetal midbrain precursor cells.
J. Maciaczyk, I. Singeç, D. Maciaczyk, G. Nikkhah
2008Experimental Neurology43 citations
Semantic Scholar
Scalable generation of sensory neurons from human pluripotent stem cells
Tao Deng, V. Jovanovic, C. Tristan, C. Weber +18 more
2023Stem Cell Reports41 citations Open access
Semantic Scholar
Quantitative Analysis of Human Pluripotency and Neural Specification by In-Depth (Phospho)Proteomic Profiling
I. Singeç, A. Crain, Jun-Jie Hou, Brian T. D. Tobe +12 more
2016Stem Cell Reports34 citations Open access
Semantic Scholar
Efficient and safe single-cell cloning of human pluripotent stem cells by using the CEPT cocktail
C. Tristan, Hyenjong Hong, Yogita Jethmalani, Yu Chen +8 more
2022Nature Protocols33 citations
Semantic Scholar
Robotic High-Throughput Biomanufacturing and Functional Differentiation of Human Pluripotent Stem Cells
C. Tristan, P. Ormanoglu, J. Slamecka, C. Malley +13 more
2020bioRxiv31 citations Open access
Semantic Scholar
A sensitive green fluorescent protein biomarker of N‐glycosylation site occupancy
Marie-Estelle Losfeld, Francesca Soncin, B. Ng, I. Singeç +1 more
2012The FASEB Journal28 citations Open access
Semantic Scholar
Restricted Spontaneous In Vitro Differentiation and Region-Specific Migration of Long-Term Expanded Fetal Human Neural Precursor Cells After Transplantation Into the Adult Rat Brain
J. Maciaczyk, I. Singeç, D. Maciaczyk, Alexander Klein +1 more
2009Stem Cells and Development28 citations
Semantic Scholar
Human OPRM1 and murine Oprm1 promoter driven viral constructs for genetic access to μ-opioidergic cell types
Gregory J. Salimando, Sébastien Tremblay, Blake A. Kimmey, Jia Li +21 more
2023Nature Communications19 citations Open access
Semantic Scholar
Bortezomib-induced neurotoxicity in human neurons is the consequence of nicotinamide adenine dinucleotide depletion
Andrew R. Snavely, Keungjung Heo, Veselina Petrova, T. Ho +8 more
2022Disease Models & Mechanisms18 citations Open access
Semantic Scholar
SEQUIN is an R/Shiny framework for rapid and reproducible analysis of RNA-seq data.
C. Weber, M. Hirst, Ben Ernest, Nicholas J. Schaub +6 more
2023Cell Reports Methods15 citations Open access
Semantic Scholar
Phosphoproteomic analysis: An emerging role in deciphering cellular signaling in human embryonic stem cells and their differentiated derivatives
Brian T. D. Tobe, Jun-Jie Hou, A. Crain, I. Singeç +2 more
2011Stem Cell Reviews and Reports13 citations Open access
Semantic Scholar
Stress-free cell aggregation by using the CEPT cocktail enhances embryoid body and organoid fitness
Seungmi Ryu, C. Weber, Pei-Hsuan Chu, Ben Ernest +13 more
2023Biofabrication11 citations Open access
Semantic Scholar
Satellite glial contact enhances differentiation and maturation of human iPSC-derived sensory neurons
Chelsey J. LeBlang, Maria F. Pazyra-Murphy, Elizabeth S. Silagi, Srestha Dasgupta +13 more
2024bioRxiv10 citations Open access
Semantic Scholar
Detecting Secretory Proteins by Acoustic Droplet Ejection in Multiplexed High-Throughput Applications
Michael J Iannotti, R. Macarthur, Richard Jones, D. Tao +3 more
2019ACS Chemical Biology8 citations Open access
Semantic Scholar
Human Pluripotent Stem Cells for High-Throughput Drug Screening and Characterization of Small Molecules
Seungmi Ryu, Pei-Hsuan Chu, C. Malley, John C. Braisted +10 more
2021Methods in molecular biology7 citations Open access
Semantic Scholar
Different testosterone metabolism by immortalized embryonic and postnatal hippocampal neurons from C57BL/6 mice: A crucial role for androstenedione
C. Hagemeyer, H. Rosenbrock, I. Singeç, R. Knoth +1 more
20007 citations
Semantic Scholar
Central nervous system repair and stem cells
Rahul Jandial, I. Singeç, Vincent J. Duenas, Allen L. Ho +2 more
20076 citations
Semantic Scholar
A versatile polypharmacology platform promotes cytoprotection and viability of human pluripotent and differentiated cells
Yu Chen, C. Tristan, Lu Chen, V. Jovanovic +14 more
2021Nature Methods5 citations Open access
Semantic Scholar
Quo vadis brain repair? A long axonal journey in the adult CNS.
I. Singeç, E. Snyder
2007Cell Stem Cell5 citations Open access
Semantic Scholar
Highly efficient generation of self-renewing trophoblast from human pluripotent stem cells
Jaroslav Slamecka, Seungmi Ryu, C. Tristan, Pei-Hsuan Chu +7 more
2024iScience4 citations Open access
Semantic Scholar
Prospects of Pluripotent and Adult Stem Cells for Rare Diseases.
J. García-Castro, I. Singeç
2017Advances in Experimental Medicine and Biology4 citations
Semantic Scholar
Combined total proteomic and phosphoproteomic analysis of human pluripotent stem cells.
Jun-Jie Hou, Brian T. D. Tobe, Frederick Lo, Justin D. Blethrow +5 more
2013Methods in molecular biology4 citations
Semantic Scholar
Cell Therapy for Neurodegenerative Disorders
I. Singeç
20134 citations
Semantic Scholar
Scalable Hypothalamic Arcuate Neuron Differentiation from Human Pluripotent Stem Cells Suitable for Modeling Metabolic and Reproductive Disorders
V. Jovanovic, N. Narisu, L. Bonnycastle, Ravi Tharakan +24 more
2024bioRxiv3 citations
Semantic Scholar
Scalable Generation of Pseudo-Unipolar Sensory Neurons from Human Pluripotent Stem Cells
Tao Deng, C. Tristan, C. Weber, Pei-Hsuan Chu +13 more
2022bioRxiv3 citations Open access
Semantic Scholar
Different testosterone metabolism by immortalized embryonic and postnatal hippocampal neurons from C57BL/6 mice: a crucial role for androstenedione.
C. Hagemeyer, H. Rosenbrock, I. Singeç, R. Knoth +1 more
2000Journal of Neuroscience Research3 citations
Semantic Scholar
A human iPSC-derived sensory neuron platform for high-throughput discovery of neuroprotectants against chemotherapy-induced peripheral neuropathy
V. Petrova, Caitlin E. Mills, Clemens Hug, Aysel Cetinkaya-Fisgin +19 more
2026Cell Reports Medicine2 citations Open access
Semantic Scholar
Modeling Friedreich’s ataxia with Bergmann glia-enriched human cerebellar organoids
Seungmi Ryu, Jason Inman, Hyenjong Hong, V. Jovanovic +10 more
2025bioRxiv2 citations
Semantic Scholar
Enhancing the Fitness of Embryoid Bodies and Organoids by Chemical Cytoprotection
Seungmin Ryu, C. Weber, Pei-Hsuan Chu, C. Tristan +10 more
2022bioRxiv2 citations Open access
Semantic Scholar
SEQUIN: rapid and reproducible analysis of RNA-seq data in R/Shiny
C. Weber, M. Hirst, Ben Ernest, Hannah M. Baskir +3 more
2022bioRxiv1 citations Open access
Semantic Scholar
Directed Differentiation of Human Pluripotent Stem Cells into Radial Glia and Astrocytes Bypasses Neurogenesis
V. Jovanovic, C. Malley, C. Tristan, Seungmi Ryu +8 more
2021bioRxiv1 citations Open access
Semantic Scholar
Detecting Secretory Proteins by Acoustic Droplet Ejection in Multiplexed High-Throughput Applications.
Michael J Iannotti, R. Macarthur, R. Jones, Ding-Yin Tao +3 more
2019ACS Chemical Biology1 citations Open access
Semantic Scholar
Chemically-Defined Neural Conversion of Human Pluripotent Stem Cells
Yu Chen, C. Tristan, S. K. Mallanna, P. Ormanoglu +3 more
2019Methods in molecular biology1 citations Open access
Semantic Scholar
The rostral migratory stream generates hippocampal CA1 pyramidal-like neurons in a novel organotypic slice co-culture model
I. Singeç, R. Knoth, I. Vida, M. Frotscher
2015Biology Open1 citations Open access
Semantic Scholar
Modeling Friedreich’s ataxia with Bergmann glia-enriched human cerebellar organoids
Seungmi Ryu, Jason Inman, Hyenjong Hong, V. Jovanovic +12 more
2026Communications Biology0 citations Open access
Semantic Scholar

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C. Tristan — researcher profile on SciRah
V. Jovanovic×15
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Seungmi Ryu — researcher profile on SciRah

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E. Snyder — researcher profile on SciRah

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C. Weber — researcher profile on SciRah

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R. Knoth — researcher profile on SciRah

Sam G. Michael×8

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Hyenjong Hong×7

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Yogita Jethmalani×7

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Yogita Jethmalani — researcher profile on SciRah