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A. Kawashima · SciRah

Researcher profile · Semantic Scholar

A. Kawashima

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A. Kawashima — researcher profile on SciRah

h-index: 34
Works: 140
Citations: 3,558

Most-cited papers

The progression of vascular calcification and serum osteoprotegerin levels in patients on long-term hemodialysis.
K. Nitta, T. Akiba, K. Uchida, A. Kawashima +3 more
2003American Journal of Kidney Diseases197 citations
Semantic Scholar
Inflammasome Activation by Mitochondrial Oxidative Stress in Macrophages Leads to the Development of Angiotensin II–Induced Aortic Aneurysm
Fumitake Usui, K. Shirasuna, Hiroaki Kimura, Kazuki Tatsumi +9 more
2015Arteriosclerosis, Thrombosis and Vascular Biology180 citations Open access
Semantic Scholar
Critical role of caspase-1 in vascular inflammation and development of atherosclerosis in Western diet-fed apolipoprotein E-deficient mice.
Fumitake Usui, K. Shirasuna, Hiroaki Kimura, Kazuki Tatsumi +6 more
2012Biochemical and Biophysical Research Communications - BBRC180 citations
Semantic Scholar
Iodine Excess as an Environmental Risk Factor for Autoimmune Thyroid Disease
Yuqian Luo, A. Kawashima, Y. Ishido, A. Yoshihara +5 more
2014International Journal of Molecular Sciences169 citations Open access
Semantic Scholar
Saturated Fatty Acids Undergo Intracellular Crystallization and Activate the NLRP3 Inflammasome in Macrophages
T. Karasawa, A. Kawashima, Fumitake Usui-Kawanishi, Sachiko Watanabe +12 more
2018Arteriosclerosis, Thrombosis and Vascular Biology139 citations Open access
Semantic Scholar
Current status of leprosy: Epidemiology, basic science and clinical perspectives
Koichi Suzuki, Takeshi Akama, A. Kawashima, A. Yoshihara +2 more
2012Journal of dermatology (Print)133 citations Open access
Semantic Scholar
NLRP3 Regulates Neutrophil Functions and Contributes to Hepatic Ischemia–Reperfusion Injury Independently of Inflammasomes
Yoshiyuki Inoue, K. Shirasuna, Hiroaki Kimura, Fumitake Usui +14 more
2014Journal of Immunology130 citations Open access
Semantic Scholar
ARIH2 Ubiquitinates NLRP3 and Negatively Regulates NLRP3 Inflammasome Activation in Macrophages
A. Kawashima, T. Karasawa, K. Tago, Hiroaki Kimura +9 more
2017Journal of Immunology127 citations Open access
Semantic Scholar
Role of NLRP3 Inflammasomes for Rhabdomyolysis-induced Acute Kidney Injury
T. Komada, Fumitake Usui, A. Kawashima, Hiroaki Kimura +9 more
2015Scientific Reports95 citations Open access
Semantic Scholar
Innate immune activation and thyroid autoimmunity.
A. Kawashima, Kazunari Tanigawa, Takeshi Akama, A. Yoshihara +2 more
2011Journal of Clinical Endocrinology and Metabolism70 citations Open access
Semantic Scholar
NLRP3 Deficiency Improves Angiotensin II-Induced Hypertension But Not Fetal Growth Restriction During Pregnancy.
K. Shirasuna, T. Karasawa, Fumitake Usui, Motoi Kobayashi +6 more
2015Endocrinology69 citations
Semantic Scholar
Pathogenicity and virulence of Mycobacterium leprae
Mariko Sugawara-Mikami, Kazunari Tanigawa, A. Kawashima, Mitsuo Kiriya +3 more
2022Virulence68 citations Open access
Semantic Scholar
Nanosilica-induced placental inflammation and pregnancy complications: Different roles of the inflammasome components NLRP3 and ASC
K. Shirasuna, Fumitake Usui, T. Karasawa, Hiroaki Kimura +9 more
2015Nanotoxicology67 citations
Semantic Scholar
ASC in renal collecting duct epithelial cells contributes to inflammation and injury after unilateral ureteral obstruction.
T. Komada, Fumitake Usui, K. Shirasuna, A. Kawashima +10 more
2014American Journal of Pathology66 citations Open access
Semantic Scholar
Interleukin-17 deficiency reduced vascular inflammation and development of atherosclerosis in Western diet-induced apoE-deficient mice.
Fumitake Usui, Hiroaki Kimura, Taichi Ohshiro, Kazuki Tatsumi +5 more
2012Biochemical and Biophysical Research Communications - BBRC66 citations
Semantic Scholar
NLRP3 Deficiency Reduces Macrophage Interleukin-10 Production and Enhances the Susceptibility to Doxorubicin-induced Cardiotoxicity
Motoi Kobayashi, Fumitake Usui, T. Karasawa, A. Kawashima +7 more
2016Scientific Reports65 citations Open access
Semantic Scholar
Whole-Genome Tiling Array Analysis of Mycobacterium leprae RNA Reveals High Expression of Pseudogenes and Noncoding Regions
Takeshi Akama, Koichi Suzuki, Kazunari Tanigawa, A. Kawashima +5 more
2009Journal of Bacteriology64 citations Open access
Semantic Scholar
Expression of adipose differentiation-related protein (ADRP) and perilipin in macrophages infected with Mycobacterium leprae.
Kazunari Tanigawa, Koichi Suzuki, Kazuaki Nakamura, Takeshi Akama +7 more
2008FEMS Microbiology Letters64 citations
Semantic Scholar
Four week supplementation with mixed fruit and vegetable juice concentrates increased protective serum antioxidants and folate and decreased plasma homocysteine in Japanese subjects.
A. Kawashima, T. Madarame, Hiroto Koike, Y. Komatsu +1 more
2007Asia Pacific Journal of Clinical Nutrition61 citations
Semantic Scholar
Fragments of genomic DNA released by injured cells activate innate immunity and suppress endocrine function in the thyroid.
A. Kawashima, Kazunari Tanigawa, Takeshi Akama, Huhehasi Wu +11 more
2011Endocrinology58 citations Open access
Semantic Scholar
NLRP3 Protein Deficiency Exacerbates Hyperoxia-induced Lethality through Stat3 Protein Signaling Independent of Interleukin-1β*
Y. Mizushina, K. Shirasuna, Fumitake Usui, T. Karasawa +13 more
2014Journal of Biological Chemistry57 citations Open access
Semantic Scholar
Demonstration of Innate Immune Responses in the Thyroid Gland: Potential to Sense Danger and a Possible Trigger for Autoimmune Reactions
A. Kawashima, K. Yamazaki, T. Hara, Takeshi Akama +9 more
2013Thyroid51 citations Open access
Semantic Scholar
Oligomerized CARD16 promotes caspase-1 assembly and IL-1β processing
T. Karasawa, A. Kawashima, Fumitake Usui, Hiroaki Kimura +7 more
2015FEBS Open Bio49 citations Open access
Semantic Scholar
Effects of an Angiotensin II Receptor Antagonist and Angiotensin-Converting Enzyme Inhibitors on Burst Forming Units-Erythroid in Chronic Hemodialysis Patients
M. Naito, A. Kawashima, T. Akiba, M. Takanashi +1 more
2003American Journal of Nephrology47 citations
Semantic Scholar
Soluble Osteopontin and Vascular Calcification in Hemodialysis Patients
K. Nitta, Tsutomu Ishizuka, S. Horita, Tetsuo Hayashi +9 more
2001Nephron47 citations
Semantic Scholar
Detection of Mycobacterium leprae DNA from Archaeological Skeletal Remains in Japan Using Whole Genome Amplification and Polymerase Chain Reaction
Koichi Suzuki, W. Takigawa, Kazunari Tanigawa, Kazuaki Nakamura +8 more
2010PLoS ONE43 citations Open access
Semantic Scholar
Regulation of Dual Oxidase Expression and H2O2 Production by Thyroglobulin
A. Yoshihara, T. Hara, A. Kawashima, Takeshi Akama +8 more
2012Thyroid42 citations Open access
Semantic Scholar
Role of thyroglobulin on negative feedback autoregulation of thyroid follicular function and growth.
Koichi Suzuki, A. Kawashima, A. Yoshihara, Takeshi Akama +3 more
2011Journal of Endocrinology42 citations Open access
Semantic Scholar
Interferon-Tau Attenuates Uptake of Nanoparticles and Secretion of Interleukin-1β in Macrophages
K. Hara, K. Shirasuna, Fumitake Usui, T. Karasawa +7 more
2014PLoS ONE39 citations Open access
Semantic Scholar
Characterization of Th1/Th2 Profile in Uremic Patients
K. Nitta, T. Akiba, A. Kawashima, N. Kimata +6 more
2002Nephron36 citations
Semantic Scholar
In vitro TGF-beta1 antagonistic activity of ursolic and oleanolic acids isolated from Clerodendranthus spicatus.
Hiromitsu Yoshimura, K. Sugawara, M. Saito, S. Saito +7 more
2003Planta Medica34 citations
Semantic Scholar
Immunoproteasome subunit LMP7 Deficiency Improves Obesity and Metabolic Disorders
Hiroaki Kimura, Fumitake Usui, T. Karasawa, A. Kawashima +11 more
2015Scientific Reports32 citations Open access
Semantic Scholar
Tryptophan aspartate‐containing coat protein (CORO1A) suppresses Toll‐like receptor signalling in Mycobacterium leprae infection
Kazunari Tanigawa, Koichi Suzuki, Hiroaki Kimura, F. Takeshita +4 more
2009Clinical and Experimental Immunology30 citations Open access
Semantic Scholar
Propylthiouracil Increases Sodium/Iodide Symporter Gene Expression and Iodide Uptake in Rat Thyroid Cells in the Absence of TSH
M. Sue, Takeshi Akama, A. Kawashima, H. Nakamura +10 more
2012Thyroid28 citations Open access
Semantic Scholar
Inhibitory effects of methimazole and propylthiouracil on iodotyrosine deiodinase 1 in thyrocytes.
A. Yoshihara, Yuqian Luo, Y. Ishido, Kensei Usukura +5 more
2019Endocrine journal27 citations Open access
Semantic Scholar
Identification of microRNAs that mediate thyroid cell growth induced by TSH.
Takeshi Akama, M. Sue, A. Kawashima, Huhehasi Wu +7 more
2012Molecular Endocrinology25 citations Open access
Semantic Scholar
Host-Related Laboratory Parameters for Leprosy Reactions
Yuqian Luo, Mitsuo Kiriya, Kazunari Tanigawa, A. Kawashima +3 more
2021Frontiers in Medicine23 citations Open access
Semantic Scholar
Design and synthesis of the tumor-activated prodrug of dihydropyrimidine dehydrogenase (DPD) inhibitor, RO0094889 for combination therapy with capecitabine.
Kazuo Hattori, Y. Kohchi, N. Oikawa, Hitomi Suda +10 more
2003Bioorganic & Medicinal Chemistry Letters23 citations Open access
Semantic Scholar
Trehalose alleviates oxidative stress-mediated liver injury and Mallor-Denk body formation via activating autophagy in mice
Yuichi Honma, Miyuki Sato-Morita, Yuka Katsuki, Hitomi Mihara +5 more
2020Medical Molecular Morphology22 citations
Semantic Scholar
Role of Extrachromosomal Histone H2B on Recognition of DNA Viruses and Cell Damage
K. Kobiyama, A. Kawashima, N. Jounai, F. Takeshita +3 more
2013Frontiers in Genetics22 citations Open access
Semantic Scholar
Caspase-1 deficiency promotes high-fat diet-induced adipose tissue inflammation and the development of obesity.
Hiroaki Kimura, T. Karasawa, Fumitake Usui, A. Kawashima +9 more
2016American Journal of Physiology. Endocrinology and Metabolism21 citations
Semantic Scholar
Essential role of hormone-sensitive lipase (HSL) in the maintenance of lipid storage in Mycobacterium leprae-infected macrophages.
Kazunari Tanigawa, De-Gang Yang, A. Kawashima, Takeshi Akama +5 more
2012Microbial Pathogenesis21 citations Open access
Semantic Scholar
Pathological role of excessive DNA as a trigger of keratinocyte proliferation in psoriasis
Y. Luo, T. Hara, A. Kawashima, Y. Ishido +4 more
2020Clinical and Experimental Immunology19 citations Open access
Semantic Scholar
Essential Roles of PPARs in Lipid Metabolism during Mycobacterial Infection
Kazunari Tanigawa, Yuqian Luo, A. Kawashima, Mitsuo Kiriya +3 more
2021International Journal of Molecular Sciences17 citations Open access
Semantic Scholar
Radon Therapy for Autoimmune Diseases Pemphigus and Diabetes: 2 Case Reports
S. Kojima, J. Cuttler, N. Shimura, Hironobu Koga +2 more
2019Dose-Response17 citations Open access
Semantic Scholar
Effects of BSO and L‐Cysteine on Drug‐Induced Cytotoxicity in Primary Cell Cultures: Drug‐, Cell Type‐, and Species‐Specific Difference
Yongke Lu, A. Kawashima, I. Horii, Lai-Fu Zhong
2004Drug and chemical toxicology (New York, N.Y. 1978)17 citations
Semantic Scholar
Analysis of Mycobacterium leprae gene expression using DNA microarray.
Takeshi Akama, Kazunari Tanigawa, A. Kawashima, Huhehasi Wu +2 more
2010Microbial Pathogenesis16 citations
Semantic Scholar
Cisplatin-Induced Cytotoxicity in BSO-Exposed Renal Proximal Tubular Epithelial Cells: Sex, Age, and Species
Yongke Lu, A. Kawashima, I. Horii, Lai-Fu Zhong
2005Renal Failure15 citations Open access
Semantic Scholar
Regulation of solute carrier family 26 member 7 (Slc26a7) by thyroid stimulating hormone in thyrocytes.
Yuta Tanimura, Mitsuo Kiriya, A. Kawashima, H. Mori +3 more
2021Endocrine journal14 citations Open access
Semantic Scholar
Amyloidosis: Multisystem Spectrum of Disease with Pathologic Correlation.
M. Sugi, A. Kawashima, M. Salomao, S. Bhalla +2 more
2021Radiographics14 citations
Semantic Scholar

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Hiroaki Kimura×19
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Hiroaki Kimura — researcher profile on SciRah
Masafumi Takahashi×16
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Masafumi Takahashi — researcher profile on SciRah
N. Ishii×16
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N. Ishii — researcher profile on SciRah
T. Karasawa×15
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T. Karasawa — researcher profile on SciRah

Kazunari Tanigawa

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Kazunari Tanigawa — researcher profile on SciRah

Fumitake Usui×14

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Takeshi Akama×14

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Takeshi Akama — researcher profile on SciRah

K. Shirasuna×12

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K. Shirasuna — researcher profile on SciRah

A. Yoshihara×12

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A. Yoshihara — researcher profile on SciRah

Koichi Suzuki×11

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Koichi Suzuki — researcher profile on SciRah

Koichi Suzuki×11

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Koichi Suzuki — researcher profile on SciRah

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Y. Ishido — researcher profile on SciRah