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S. Velupillai · SciRah

Researcher profile · Semantic Scholar

S. Velupillai

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S. Velupillai — researcher profile on SciRah

h-index: 8
Works: 55
Citations: 836

Most-cited papers

Rapid Covalent-Probe Discovery by Electrophile-Fragment Screening
E. Resnick, A. Bradley, Jin-Rui Gan, A. Douangamath +30 more
2018bioRxiv288 citations Open access
Semantic Scholar
Structural analysis of human KDM5B guides histone demethylase inhibitor development.
C. Johansson, S. Velupillai, A. Tumber, A. Szykowska +20 more
2016Nature Chemical Biology175 citations Open access
Semantic Scholar
Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells
A. Tumber, A. Nuzzi, E. Hookway, S. Hatch +24 more
2017Cell Chemical Biology114 citations Open access
Semantic Scholar
8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors
V. Bavetsias, R. Lanigan, G. F. Ruda, B. Atrash +39 more
2016Journal of Medicinal Chemistry87 citations Open access
Semantic Scholar
Phosphorylation of Synaptic Vesicle Protein 2A at Thr84 by Casein Kinase 1 Family Kinases Controls the Specific Retrieval of Synaptotagmin-1
Ning Zhang, S. Gordon, M. J. Fritsch, Noor Esoof +8 more
2015Journal of Neuroscience71 citations Open access
Semantic Scholar
Docking and Linking of Fragments To Discover Jumonji Histone Demethylase Inhibitors
M. Korczynska, D. Le, N. Younger, E. Gregori-Puigjané +11 more
2015Journal of Medicinal Chemistry48 citations Open access
Semantic Scholar
A Chemical Probe for Tudor Domain Protein Spindlin1 to Investigate Chromatin Function.
V. Fagan, C. Johansson, C. Gileadi, Octovia P. Monteiro +30 more
2019Journal of Medicinal Chemistry37 citations Open access
Semantic Scholar
C8-substituted pyrido[3,4-d]pyrimidin-4(3H)-ones: Studies towards the identification of potent, cell penetrant Jumonji C domain containing histone lysine demethylase 4 subfamily (KDM4) inhibitors, compound profiling in cell-based target engagement assays
Y. Le Bihan, Rachel M. Lanigan, B. Atrash, Mark G. McLaughlin +25 more
2019European journal of medicinal chemistry14 citations Open access
Semantic Scholar
Deliberately Losing Control of C−H Activation Processes in the Design of Small‐Molecule‐Fragment Arrays Targeting Peroxisomal Metabolism
Raysa Khan Tareque, Storm Hassell-Hart, T. Krojer, A. Bradley +12 more
2020ChemMedChem2 citations Open access
Semantic Scholar
Human peroxisomal coenzyme A diphosphatase (NUDT7): a target enabling package (TEP)
S. Velupillai, L. D. Sáez, T. Krojer, J. Bennett +15 more
20181 citations
Semantic Scholar
Crystal structure of human CUL3 N-terminal domain bound to KEAP1 BTB and 3-box
R. Adamson, T. Krojer, D. Pinkas, S. G. Bartual +15 more
20171 citations
Semantic Scholar
Investigating the localization mechanism of Bsg25D mRNA in Drosophila melanogaster
S. Velupillai
20200 citations
Semantic Scholar
PanDDA analysis group deposition -- Crystal Structure of DCP2 (NUDT20) in complex with Z2895259675
E. R. Nelson, S. Velupillai, R. Talon, P. Collins +9 more
20190 citations
Semantic Scholar
PanDDA analysis group deposition -- Crystal Structure of DCP2 (NUDT20) in complex with XST00000847b
E. R. Nelson, S. Velupillai, R. Talon, P. Collins +9 more
20190 citations
Semantic Scholar
PanDDA analysis group deposition -- Crystal Structure of DCP2 (NUDT20) in complex with NUOOA000023a
E. R. Nelson, S. Velupillai, R. Talon, P. Collins +9 more
20190 citations
Semantic Scholar
PanDDA analysis group deposition -- Crystal Structure of DCP2 (NUDT20) in complex with Z1699011516
E. R. Nelson, S. Velupillai, R. Talon, P. Collins +9 more
20190 citations
Semantic Scholar
PanDDA analysis group deposition -- Crystal Structure of DCP2 (NUDT20) in complex with Z1187701032
E. R. Nelson, S. Velupillai, R. Talon, P. Collins +9 more
20190 citations
Semantic Scholar
PanDDA analysis group deposition -- Crystal Structure of DCP2 (NUDT20) in complex with FMOPL000449a
E. R. Nelson, S. Velupillai, R. Talon, P. Collins +9 more
20190 citations
Semantic Scholar
PanDDA analysis group deposition -- Crystal Structure of DCP2 (NUDT20) in complex with Z1203490773
E. R. Nelson, S. Velupillai, R. Talon, P. Collins +9 more
20190 citations
Semantic Scholar
PanDDA analysis group deposition -- Crystal Structure of DCP2 (NUDT20) in complex with PB1787571279
E. R. Nelson, S. Velupillai, R. Talon, P. Collins +9 more
20190 citations
Semantic Scholar
PanDDA analysis group deposition -- Crystal Structure of DCP2 (NUDT20) in complex with Z1190363272
E. R. Nelson, S. Velupillai, R. Talon, P. Collins +9 more
20190 citations
Semantic Scholar
PanDDA analysis group deposition -- Crystal Structure of DCP2 (NUDT20) in complex with Z100435060
E. R. Nelson, S. Velupillai, R. Talon, P. Collins +9 more
20190 citations
Semantic Scholar
PanDDA analysis group deposition -- Crystal Structure of DCP2 (NUDT20) in complex with Z1170065264
E. R. Nelson, S. Velupillai, R. Talon, P. Collins +9 more
20190 citations
Semantic Scholar
Crystal structure of human KDM5B in complex with compound 34a
Y. Le Bihan, S. Velupillai, R. van Montfort
20190 citations
Semantic Scholar
Crystal structure of human KDM5B in complex with compound 34f
Y. Le Bihan, S. Velupillai, R. van Montfort
20190 citations
Semantic Scholar
PanDDA analysis group deposition -- Crystal Structure of DCP2 (NUDT20) in complex with Z450133538
E. R. Nelson, S. Velupillai, R. Talon, P. Collins +9 more
20190 citations
Semantic Scholar
PanDDA analysis group deposition -- Crystal Structure of DCP2 (NUDT20) in complex with YW-FY-378
E. R. Nelson, S. Velupillai, R. Talon, P. Collins +9 more
20190 citations
Semantic Scholar
A Chemical Probe For Tudor Domain Protein Spin1 to Investigate Chromatin Functions
Vincent Fagan, C. Johansson, C. Gileadi, Octovia P. Monteiro +30 more
20190 citations Open access
Semantic Scholar
PanDDA analysis group deposition -- Crystal Structure of DCP2 (NUDT20) in complex with FMOPL000435a
E. R. Nelson, S. Velupillai, R. Talon, P. Collins +9 more
20190 citations
Semantic Scholar
PanDDA analysis group deposition -- Crystal Structure of DCP2 (NUDT20) in complex with Z296300542
E. R. Nelson, S. Velupillai, R. Talon, P. Collins +9 more
20190 citations
Semantic Scholar
PanDDA analysis group deposition -- Crystal Structure of DCP2 (NUDT20) in complex with Z2212124043
E. R. Nelson, S. Velupillai, R. Talon, P. Collins +9 more
20190 citations
Semantic Scholar
PanDDA analysis group deposition -- Crystal Structure of DCP2 (NUDT20) in complex with Z1662802141
E. R. Nelson, S. Velupillai, R. Talon, P. Collins +9 more
20190 citations
Semantic Scholar
PanDDA analysis group deposition -- Crystal Structure of DCP2 (NUDT20) in complex with Z2895259681
E. R. Nelson, S. Velupillai, R. Talon, P. Collins +9 more
20190 citations
Semantic Scholar
PanDDA analysis group deposition -- Crystal Structure of DCP2 (NUDT20) in complex with Z2895259680
E. R. Nelson, S. Velupillai, R. Talon, P. Collins +9 more
20190 citations
Semantic Scholar
PanDDA analysis group deposition -- Crystal Structure of DCP2 (NUDT20) in complex with FMOPL000213a
E. R. Nelson, S. Velupillai, R. Talon, P. Collins +9 more
20190 citations
Semantic Scholar
PanDDA analysis group deposition -- Crystal Structure of DCP2 (NUDT20) in complex with Z1494850193
E. R. Nelson, S. Velupillai, R. Talon, P. Collins +9 more
20190 citations
Semantic Scholar
PanDDA analysis group deposition -- Crystal Structure of DCP2 (NUDT20) in complex with FMOPL000576a
E. R. Nelson, S. Velupillai, R. Talon, P. Collins +9 more
20190 citations
Semantic Scholar
PanDDA analysis group deposition -- Crystal Structure of DCP2 (NUDT20) in complex with FMOPL000701a
E. R. Nelson, S. Velupillai, R. Talon, P. Collins +9 more
20190 citations
Semantic Scholar
PanDDA analysis group deposition -- Crystal Structure of DCP2 (NUDT20) in complex with FMOCR000171b
E. R. Nelson, S. Velupillai, R. Talon, P. Collins +9 more
20190 citations
Semantic Scholar
PanDDA analysis group deposition -- Crystal Structure of DCP2 (NUDT20) in complex with FMOPL000294a
E. R. Nelson, S. Velupillai, R. Talon, P. Collins +9 more
20190 citations
Semantic Scholar
Crystal structure of human KDM5B in complex with compound 16a
Y. Le Bihan, S. Velupillai, R. van Montfort
20190 citations
Semantic Scholar
PanDDA analysis group deposition -- Crystal Structure of DCP2 (NUDT20) in complex with Z1592710382
E. R. Nelson, S. Velupillai, R. Talon, P. Collins +9 more
20190 citations
Semantic Scholar
PanDDA analysis group deposition -- Crystal Structure of DCP2 (NUDT20) in complex with PB1230873739
E. R. Nelson, S. Velupillai, R. Talon, P. Collins +9 more
20190 citations
Semantic Scholar
Crystal Structure of DCP2 (NUDT20) after initial refinement with no ligand modelled (structure $n)
E. R. Nelson, S. Velupillai, R. Talon, P. Collins +9 more
20190 citations
Semantic Scholar
PanDDA analysis group deposition -- Crystal Structure of DCP2 (NUDT20) in complex with FMOPL000446a
E. R. Nelson, S. Velupillai, R. Talon, P. Collins +9 more
20190 citations
Semantic Scholar
PanDDA analysis group deposition -- Crystal Structure of DCP2 (NUDT20) in complex with Z454376544
E. R. Nelson, S. Velupillai, R. Talon, P. Collins +9 more
20190 citations
Semantic Scholar
PanDDA analysis group deposition -- Crystal Structure of DCP2 (NUDT20) in complex with FMOPL000144a
E. R. Nelson, S. Velupillai, R. Talon, P. Collins +9 more
20190 citations
Semantic Scholar
Crystal structure of human KDM5B in complex with compound 34g
Y. Le Bihan, S. Velupillai, R. van Montfort
20190 citations
Semantic Scholar
Edinburgh Research Explorer Phosphorylation of Synaptic Vesicle Protein 2A at Thr84 by Casein Kinase 1 Family Kinases Controls the Specific Retrieval of Synaptotagmin-1
Ning Zhang, S. Gordon, M. J. Fritsch, Noor Esoof +8 more
20180 citations
Semantic Scholar
Crystal Structure of Human Dihydropyrimidinease-like 2 (DPYSL2A)/Collapsin Response Mediator Protein (CRMP2 13-516) Mutant Y479E/Y499E
R. Sethi, Yiyan Zheng, R. Talon, S. Velupillai +5 more
20170 citations
Semantic Scholar

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