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A. Sundstedt · SciRah

Researcher profile · Semantic Scholar

A. Sundstedt

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A. Sundstedt — researcher profile on SciRah

h-index: 23
Works: 55
Citations: 1,711

Most-cited papers

Role for IL-10 in Suppression Mediated by Peptide-Induced Regulatory T Cells In Vivo 1
A. Sundstedt, E. O'Neill, K. Nicolson, D. Wraith
2003Journal of Immunology177 citations Open access
Semantic Scholar
Immunoregulatory role of IL-10 during superantigen-induced hyporesponsiveness in vivo.
A. Sundstedt, I. Höidén, A. Rosendahl, T. Kalland +2 more
1997Journal of Immunology158 citations
Semantic Scholar
Cytokine-Induced Src Homology 2 Protein (Cis) Promotes T Cell Receptor–Mediated Proliferation and Prolongs Survival of Activated T Cells
Su-Ling Li, Shang-Wu Chen, Xiufeng Xu, A. Sundstedt +5 more
2000Journal of Experimental Medicine123 citations Open access
Semantic Scholar
In vivo anergized CD4+ T cells express perturbed AP-1 and NF-kappa B transcription factors.
A. Sundstedt, Mikael Sigvardsson, Tomas Leanderson, Gunnar Hedlund +2 more
1996Proceedings of the National Academy of Sciences of the United States of America119 citations Open access
Semantic Scholar
Bcl-3 and NFκB p50-p50 Homodimers Act as Transcriptional Repressors in Tolerant CD4+ T Cells*
Susanna Grundström, P. Anderson, P. Scheipers, A. Sundstedt
2004Journal of Biological Chemistry105 citations Open access
Semantic Scholar
Tasquinimod modulates suppressive myeloid cells and enhances cancer immunotherapies in murine models
Li Shen, A. Sundstedt, M. Ciesielski, K. M. Miles +12 more
2014Cancer immunology research89 citations Open access
Semantic Scholar
Persistent antigenic stimulation alters the transcription program in T cells, resulting in antigen-specific tolerance
P. Anderson, B. Manzo, A. Sundstedt, S. Minaee +7 more
2006European Journal of Immunology77 citations Open access
Semantic Scholar
Tasquinimod triggers an early change in the polarization of tumor associated macrophages in the tumor microenvironment
Anders H. Olsson, J. Nakhlé, A. Sundstedt, P. Plas +8 more
2015Journal of Immunotherapy for Cancer74 citations Open access
Semantic Scholar
Superantigen-Induced Regulatory T Cells Display Different Suppressive Functions in the Presence or Absence of Natural CD4+CD25+ Regulatory T Cells In Vivo1
Susanna Grundström, Lukas Cederbom, A. Sundstedt, P. Scheipers +1 more
2003Journal of Immunology72 citations Open access
Semantic Scholar
Superantigen‐induced cytokines suppress growth of human colon‐carcinoma cells
M. Dohlsten, A. Sundstedt, M. Björklund, G. Hedlund +1 more
1993International Journal of Cancer65 citations
Semantic Scholar
IL-2 Unresponsiveness in Anergic CD4+ T Cells Is Due to Defective Signaling Through the Common γ-Chain of the IL-2 Receptor1
Susanna Grundström, M. Dohlsten, A. Sundstedt
2000Journal of Immunology55 citations Open access
Semantic Scholar
Immunopharmacology of the superantigen staphylococcal enterotoxin A in T-cell receptor V beta 3 transgenic mice.
M. Dohlsten, M. Björklund, A. Sundstedt, Gunnar Hedlund +2 more
1993Immunology52 citations
Semantic Scholar
In vivo anergized CD4+ T cells have defective expression and function of the activating protein-1 transcription factor.
A. Sundstedt, M. Dohlsten
1998Journal of Immunology50 citations Open access
Semantic Scholar
Superantigens anergize cytokine production but not cytotoxicity in vivo.
A. Sundstedt, M. Dohlsten, G. Hedlund, I. Höidén +2 more
1994Immunology48 citations
Semantic Scholar
The role of cytokines in immunological tolerance: potential for therapy
Mark Harber, A. Sundstedt, D. Wraith
2000Expert Reviews in Molecular Medicine43 citations
Semantic Scholar
Antigen-Induced IL-10+ Regulatory T Cells Are Independent of CD25+ Regulatory Cells for Their Growth, Differentiation, and Function
K. Nicolson, E. O'Neill, A. Sundstedt, H. Streeter +2 more
2006Journal of Immunology40 citations Open access
Semantic Scholar
Intranasal peptide-induced peripheral tolerance: the role of IL-10 in regulatory T cell function within the context of experimental autoimmune encephalomyelitis.
E. Massey, A. Sundstedt, M. Day, G. Corfield +2 more
2002Veterinary Immunology and Immunopathology39 citations
Semantic Scholar
Superantigen-induced anergy in cytotoxic CD8+ T cells.
A. Sundstedt, I. Höidén, Johan Hansson, G. Hedlund +2 more
1995Journal of Immunology37 citations Open access
Semantic Scholar
Amelioration of experimental autoimmune encephalomyelitis by the quinoline-3-carboxamide paquinimod: reduced priming of proinflammatory effector CD4(+) T cells.
Sofia Helmersson, A. Sundstedt, Adnan Deronic, T. Leanderson +1 more
2013American Journal of Pathology34 citations
Semantic Scholar
Immune response during tumor therapy with antibody‐superantigen fusion proteins
Alexander Rosendahl, J. Hansson, A. Sundstedt, T. Kalland +1 more
1996International Journal of Cancer33 citations Open access
Semantic Scholar
Pharmacological modulation of T cell immunity results in long-term remission of autoimmune arthritis
Yi-Shu Huang, W. Tseng, F. Clanchy, L. Topping +13 more
2021Proceedings of the National Academy of Sciences of the United States of America30 citations Open access
Semantic Scholar
Natural and Induced Regulatory T Cells
E. O'Neill, A. Sundstedt, G. Mazza, Kirsty S. Nicolson +5 more
2004Annals of the New York Academy of Sciences30 citations
Semantic Scholar
Bispecific antibodies targeting CD40 and tumor-associated antigens promote cross-priming of T cells resulting in an antitumor response superior to monospecific antibodies
K. Hagerbrand, Laura A Varas, Adnan Deronic, Barnabas Nyesiga +17 more
2022Journal for ImmunoTherapy of Cancer29 citations Open access
Semantic Scholar
Immunological response and overall survival in a subset of advanced renal cell carcinoma patients from a randomized phase 2/3 study of naptumomab estafenatox plus IFN-α versus IFN-α
E. Elkord, D. Burt, A. Sundstedt, Ö. Nordle +2 more
2015OncoTarget22 citations Open access
Semantic Scholar
Combining tumor-targeted superantigens with interferon-alpha results in synergistic anti-tumor effects.
A. Sundstedt, Mona Celander, G. Hedlund
2008International Immunopharmacology21 citations
Semantic Scholar
The Tumor Targeted Superantigen ABR-217620 Selectively Engages TRBV7-9 and Exploits TCR-pMHC Affinity Mimicry in Mediating T Cell Cytotoxicity
G. Hedlund, H. Eriksson, A. Sundstedt, G. Forsberg +5 more
2013PLoS ONE18 citations Open access
Semantic Scholar
Immunotherapy with tumor-targeted superantigens (TTS) in combination with docetaxel results in synergistic anti-tumor effects.
A. Sundstedt, Mona Celander, Marie Wallén Ohman, G. Forsberg +1 more
2009International Immunopharmacology18 citations
Semantic Scholar
Monotherapeutically Nonactive CTLA-4 Blockade Results in Greatly Enhanced Antitumor Effects When Combined With Tumor-targeted Superantigens in a B16 Melanoma Model
A. Sundstedt, Mona Celander, H. Eriksson, M. Törngren +1 more
2012Journal of immunotherapy13 citations
Semantic Scholar
Tolerogenic dendritic cells generated in vitro using a novel protocol mimicking mucosal tolerance mechanisms represent a potential therapeutic cell platform for induction of immune tolerance
Gillian Dao Nyesiga, Lieneke Pool, Pavlos C. Englezou, Terese Hylander +6 more
2023Frontiers in Immunology11 citations Open access
Semantic Scholar
The Bispecific Tumor Antigen-Conditional 4–1BB x 5T4 Agonist, ALG.APV-527, Mediates Strong T-Cell Activation and Potent Antitumor Activity in Preclinical Studies
Michelle H. Nelson, S. Fritzell, Robert Miller, Doreen Werchau +25 more
2022Molecular Cancer Therapeutics10 citations Open access
Semantic Scholar
Selective induction of p38 mitogen-activated protein kinase activity following A6H co-stimulation in primary human CD4(+) T cells.
T. Labuda, A. Sundstedt, M. Dohlsten
2000International Immunology9 citations
Semantic Scholar
Monoclonal antibodies and superantigens: A novel therapeutic approach
T. Kalland, M. Dohlsten, P. Lind, A. Sundstedt +5 more
1993Medical Oncology and Tumor Pharmacotherapy7 citations
Semantic Scholar
Tumor‐Targeted Superantigens
G. Hedlund, G. Forsberg, T. Nederman, A. Sundstedt +3 more
20132 citations
Semantic Scholar
Regulatory mechanisms controlling T cell activity
A. Sundstedt
19982 citations
Semantic Scholar
581 Preliminary phase 1 results of clinical trial investigating BI-1910, a tumor necrosis factor receptor 2 (TNFR2) agonist, in solid tumor cancer patients
Tatiana Hernandez, B. Doger, J. Yachnin, K. S. Rohrberg +16 more
2025Regular and Young Investigator Award Abstracts1 citations Open access
Semantic Scholar
751 Neo-X-Prime bispecific antibodies targeting CD40 and tumor antigens promote cross-presentation of tumor exosome-derived neoantigen and induce superior anti-tumor responses compared to CD40 mAb
K. Hagerbrand, M. Levin, L. von Schantz, Laura A Varas +11 more
2021Journal for ImmunoTherapy of Cancer1 citations Open access
Semantic Scholar
Abstract B17: Immunomodulation by tasquinimod: Combination with immunotherapy results in enhanced CD8 T cell responses and improved antitumor effects.
A. Sundstedt, Anders H. Olsson, M. Stenström, Mona Celander +5 more
20131 citations
Semantic Scholar
Selective induction of p 38 mitogen-activated protein kinase activity following A 6 H co-stimulation in primary human CD 4 T cells
T. Labuda, A. Sundstedt, M. Dohlsten
20001 citations
Semantic Scholar
Anti-TNFR2 antibody BI-1808 induces tumor regression and antitumor T cell immunity through T reg and myeloid cell modulation in patients with solid tumors.
I. Teige, K. Rohrberg, A. Carneiro, J. Yachnin +28 more
2026Clinical Cancer Research0 citations Open access
Semantic Scholar
BI-1808 + pembrolizumab: Responses to a chemotherapy-free regimen in advanced ovarian cancer.
Anja Williams, R. Kristeleit, Juanita Lopez, J. Yachnin +16 more
2026Journal of Clinical Oncology0 citations
Semantic Scholar
ATOR-4066, a Bispecific Antibody Targeting CD40 and CEACAM5, Induces Strong Myeloid and T Cell–Dependent Tumor Immunity and Synergizes with PD-1 Blockade
Hampus Andersson, I. Uddback, Tova Hermodsson, Mona Celander +14 more
2025Cancer immunology research0 citations
Semantic Scholar
Abstract 5309: ATOR-4066, a Neo-X-Prime™ bispecific antibody targeting CD40 and CEACAM5, induces tumor localized immune cell activation in preclinical in vivo tumor model
Hampus Andersson, Ida Uddbäck, Mona Celander, Maria Johansson +11 more
2024Cancer Research0 citations
Semantic Scholar
Abstract 2939: ATOR-4066, a Neo-X-Prime bispecific antibody targeting CD40 and CEA, activates myeloid cells in primary human tumors in vitro and induces anti-tumor immunity in vivo
K. Hagerbrand, A. Sundstedt, M. Levin, Yago Pico de Coaña +8 more
2023Cancer Research0 citations
Semantic Scholar
837 Combination treatment with ATOR-4066, a Neo-X-Prime™ bispecific antibody targeting CD40 and CEACAM5, and anti-PD-1 reverses T cell exhaustion in vitro
Ida Uddbäck, S. Fritzell, Lill Ljung, Annelie C. Nilsson +9 more
2023Regular and Young Investigator Award Abstracts0 citations Open access
Semantic Scholar
796 ALG.APV-527: a 5T4 tumor directed bispecific approach utilizing ADAPTIRTM technology designed for conditional 4-1BB T cell/NK agonism against solid tumors
Michelle H. Nelson, A. Sundstedt, Yago Pico de Coaña, Ashly Lucas +9 more
2021Journal for ImmunoTherapy of Cancer0 citations Open access
Semantic Scholar
Treatment with zebularine-treated tolerogenic dendritic cells reduces the amount of inhibitory antibodies in rats with induced immunity to human Factor VIII
P. Ericsson, A. Maddahi, X. Jing, T. Bäckström +5 more
20180 citations
Semantic Scholar
SAT0005 DNA methylation inhibitors produce sustained remission of arthritis in mice and promote regulatory T cell responses
W. Tseng, I.-S. Huang, F. Clanchy, K. Mcnamee +7 more
20170 citations
Semantic Scholar
for Their Growth, Differentiation, and Are Independent of CD25+ Regulatory Cells Antigen-Induced IL-10+ Regulatory T Cells
H. Streeter, D. Wraith, K. Nicolson, E. O'Neill +1 more
20130 citations
Semantic Scholar
Targeting of superantigens
T. Kalland, M. Dohlsten, L. Abrahmsén, G. Hedlund +5 more
2009Cell Biophysics0 citations
Semantic Scholar
Combining tumor-targeted superantigens with docetaxel results in synergistic anti-tumor effects in B16 tumor bearing mice.
A. Sundstedt, Mona Celander, Marie Wallén Ohman, G. Forsberg +1 more
20080 citations
Semantic Scholar

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