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I. Teige · SciRah

Researcher profile · Semantic Scholar

I. Teige

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I. Teige — researcher profile on SciRah

h-index: 19
Works: 69
Citations: 2,069

Most-cited papers

Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies
F. Arce Vargas, A. Furness, K. Litchfield, K. Joshi +251 more
2018Cancer Cell554 citations Open access
Semantic Scholar
Neuron-mediated generation of regulatory T cells from encephalitogenic T cells suppresses EAE
Ya-Wei Liu, I. Teige, B. Birnir, Shohreh Issazadeh-Navikas
2006Nature Medicine321 citations
Semantic Scholar
IFN-β Gene Deletion Leads to Augmented and Chronic Demyelinating Experimental Autoimmune Encephalomyelitis1
I. Teige, A. Treschow, Anna Teige, R. Mattsson +4 more
2003Journal of Immunology155 citations Open access
Semantic Scholar
Antibodies to Costimulatory Receptor 4‐1BB Enhance Anti‐tumor Immunity via T Regulatory Cell Depletion and Promotion of CD8 T Cell Effector Function
Sarah L. Buchan, L. Dou, M. Remer, S. Booth +25 more
2018Immunity145 citations Open access
Semantic Scholar
Antagonistic human FcγRIIB (CD32B) antibodies have anti-tumor activity and overcome resistance to antibody therapy in vivo.
A. Roghanian, I. Teige, L. Mårtensson, K. Cox +28 more
2015Cancer Cell135 citations Open access
Semantic Scholar
TPA induction leads to a Th17-like response in transgenic K14/VEGF mice: a novel in vivo screening model of psoriasis.
H. Hvid, I. Teige, P. Kvist, L. Svensson +1 more
2008International Immunology82 citations Open access
Semantic Scholar
A human ICAM-1 antibody isolated by a function-first approach has potent macrophage-dependent antimyeloma activity in vivo.
Niina Veitonmäki, M. Hansson, F. Zhan, Annika Sundberg +13 more
2013Cancer Cell71 citations Open access
Semantic Scholar
IFN-β Inhibits T Cell Activation Capacity of Central Nervous System APCs1
I. Teige, Ya-Wei Liu, Shohreh Issazadeh-Navikas
2006Journal of Immunology55 citations Open access
Semantic Scholar
Encephalomyelitis Experimental Autoimmune Central Nervous System Inflammation in Cd1-dependent Regulation of Chronic
Issazadeh-Navikas Shohreh Bockermann, Emma Mondoc, R. Holmdahl, Anna Teige +3 more
54 citations
Semantic Scholar
Targeting the Antibody Checkpoints to Enhance Cancer Immunotherapy–Focus on FcγRIIB
I. Teige, L. Mårtensson, B. Frendéus
2019Frontiers in Immunology47 citations Open access
Semantic Scholar
A single-arm, open-label, phase 2 clinical trial evaluating disease response following treatment with BI-505, a human anti-intercellular adhesion molecule-1 monoclonal antibody, in patients with smoldering multiple myeloma
S. Wichert, G. Juliusson, Å. Johansson, Elisabeth Sonesson +5 more
2017PLoS ONE47 citations Open access
Semantic Scholar
Stromal cells and osteoclasts are responsible for exacerbated collagen-induced arthritis in interferon-beta-deficient mice.
A. Treschow, I. Teige, Kutty Selva Nandakumar, R. Holmdahl +1 more
2005Arthritis & Rheumatism46 citations Open access
Semantic Scholar
A Phase I Dose-Escalation Study of Antibody BI-505 in Relapsed/Refractory Multiple Myeloma
M. Hansson, P. Gimsing, A. Badros, T. Niskanen +15 more
2015Clinical Cancer Research42 citations Open access
Semantic Scholar
Development and Characterization of Monoclonal Antibodies Specific for Mouse and Human Fcγ Receptors
A. Tutt, S. James, S. Laversin, Thomas R. W. Tipton +23 more
2015Journal of Immunology41 citations Open access
Semantic Scholar
Vectorized Treg-depleting αCTLA-4 elicits antigen cross-presentation and CD8+ T cell immunity to reject ‘cold’ tumors
M. Semmrich, Jean-Baptiste Marchand, Laetitia Fend, M. Rehn +14 more
2022Journal for ImmunoTherapy of Cancer30 citations Open access
Semantic Scholar
IFN-beta inhibits T cell activation capacity of central nervous system APCs.
I. Teige, Ya-Wei Liu, Shohreh Issazadeh-Navikas
2006Journal of Immunology30 citations
Semantic Scholar
FcγRIIB controls antibody-mediated target cell depletion by ITIM-independent mechanisms
Alexander P. Simpson, A. Roghanian, Robert J. Oldham, H. Claude Chan +15 more
2022Cell Reports27 citations Open access
Semantic Scholar
Regulatory T cells control VEGF-dependent skin inflammation.
I. Teige, H. Hvid, L. Svensson, P. Kvist +1 more
2009Journal of Investigative Dermatology25 citations Open access
Semantic Scholar
Domain binding and isotype dictate the activity of anti-human OX40 antibodies
J. Griffiths, Khiyam Hussain, Hannah L. Smith, T. Sanders +17 more
2020Journal for ImmunoTherapy of Cancer24 citations Open access
Semantic Scholar
Induced keratinocyte hyper-proliferation in alpha2beta1 integrin transgenic mice results in systemic immune cell activation.
I. Teige, Alexandra Bäcklund, L. Svensson, P. Kvist +2 more
2010International Immunopharmacology16 citations
Semantic Scholar
A platform for phenotypic discovery of therapeutic antibodies and targets applied on Chronic Lymphocytic Leukemia
Anne Ljungars, L. Mårtensson, J. Mattsson, Mathilda Kovacek +13 more
2018npj Precision Oncology14 citations Open access
Semantic Scholar
Local therapy with CpG motifs in a murine model of allergic airway inflammation in IFN-β knock-out mice
V. Matheu, A. Treschow, I. Teige, V. Navikas +1 more
2005Respiratory Research13 citations Open access
Semantic Scholar
Suppression of EAE by oral tolerance is independent of endogenous IFN‐β whereas treatment with recombinant IFN‐β ameliorates EAE
Ya-Wei Liu, I. Teige, Ida Ericsson, V. Navikas +1 more
2010Immunology and Cell Biology11 citations Open access
Semantic Scholar
FcγRIIb Expression Is Decreased on Naive and Marginal Zone-Like B Cells From Females With Multiple Sclerosis
Stephanie Trend, J. Leffler, I. Teige, B. Frendéus +3 more
2021Frontiers in Immunology10 citations Open access
Semantic Scholar
Abstract 936: Targeting TNFR2 for cancer immunotherapy: Ligand blocking depletors versus receptor agonists
L. Mårtensson, Kirstie L. S. Cleary, M. Semmrich, Mathilda Kovacek +12 more
2020Immunology10 citations
Semantic Scholar
Targeting FcγRIIB by antagonistic antibody BI-1206 improves the efficacy of rituximab-based therapies in aggressive mantle cell lymphoma
V. Jiang, Yang Liu, Alexa A. Jordan, Angela Leeming +14 more
2022Journal of Hematology & Oncology9 citations Open access
Semantic Scholar
Evaluating Anti-CD32b F(ab) Conformation Using Molecular Dynamics and Small-Angle X-Ray Scattering
Emma J Sutton, Richard T. Bradshaw, C. Orr, B. Frendéus +5 more
2018Biophysical Journal8 citations Open access
Semantic Scholar
19-BI-1808-01, a phase 1/2a clinical trial of BI-1808, a tumor necrosis factor receptor 2 (TNFR2) blocker/depleter with or without pembrolizumab.
K. Rohrberg, Z. Pápai, R. Eefsen, J. Yachnin +16 more
2024Journal of Clinical Oncology6 citations Open access
Semantic Scholar
Accelerating target deconvolution for therapeutic antibody candidates using highly parallelized genome editing
J. Mattsson, Ludvig Ekdahl, Fredrik Junghus, Ram Ajore +6 more
2021Nature Communications5 citations Open access
Semantic Scholar
Abstract 5602: BT-001, an oncolytic vaccinia virus armed with a Treg-depletion-optimized recombinant human anti-CTLA4 antibody and GM-CSF to target the tumor microenvironment
Jean-Baptiste Marchand, M. Semmrich, Laetitia Fend, M. Rehn +6 more
2020Immunology5 citations
Semantic Scholar
BT-001, AN ONCOLYTIC VACCINIA VIRUS ARMED WITH A TREG-DEPLETING HUMAN RECOMBINANT ANTI-CTLA4 ANTIBODY AND GM-CSF TO TARGET THE TUMOR MICROENVIRONMENT
Laetitia Fend, M. Rehn, N. Silvestre, L. Mårtensson +4 more
20204 citations
Semantic Scholar
757 Phase 1/2a clinical trial of BI-1808, a monoclonal antibody to tumor necrosis factor receptor 2 (TNFR2) as single agent and in combination with pembrolizumab
K. S. Rohrberg, Z. Pápai, A. Carneiro, István Láng +20 more
2023Regular and Young Investigator Award Abstracts3 citations Open access
Semantic Scholar
Abstract 4156: BI-1808 - a first in class ligand-blocking αTNFR2 antibody for cancer immunotherapy
L. Mårtensson, Kirsty Cleary, P. Holmkvist, Mathilda Kovacek +16 more
2022Cancer Research3 citations
Semantic Scholar
746 Vectorized Treg-depleting anti-CTLA-4 elicits antigen cross-presentation and CD8+ T cell immunity to reject “cold” tumors
M. Semmrich, Jean-Baptiste Marchand, M. Rehn, Laetitia Fend +12 more
2021Journal for ImmunoTherapy of Cancer3 citations Open access
Semantic Scholar
Phase 1/2a Clinical Trial of BI-1206, a Monoclonal Antibody to Fcγriib, in Combination with Rituximab in Subjects with Indolent B-Cell Non-Hodgkin Lymphoma That Has Relapsed or Is Refractory to Rituximab
I. Karlsson, S. Gertsson, S. Kilany, M. Borggren +12 more
2021Blood3 citations Open access
Semantic Scholar
17-BI-1206-02 Phase 1/2a Clinical Trial of BI-1206, a Monoclonal Antibody to Fcgriib, in Combination with Rituximab in Subjects with Indolent B-Cell Non-Hodgkin Lymphoma That Has Relapsed or Is Refractory to Rituximab
M. Jerkeman, A. Mcallister, C. Roos, Marie Lindell Andersson +9 more
20203 citations
Semantic Scholar
Leveraging TNFR2 for antitumour immunity: T reg depletion and myeloid reprogramming versus T cell costimulation
L. Mårtensson, P. Holmkvist, Kirstie Cleary, Carolin Svensson +20 more
2026bioRxiv2 citations
Semantic Scholar
BI-1808, a tumor necrosis factor receptor 2 (TNFR2) blocker/depleter, showing promising efficacy in T cell lymphoma patients
S. Barta, C. Querfeld, Sean H Lim, A. Carneiro +12 more
2025Blood2 citations
Semantic Scholar
1368 Preclinical development of an agonistic anti-TNFR2 antibody (BI-1910) for cancer immunotherapy
L. Mårtensson, P. Holmkvist, Mathilda Kovacek, Carolin Svensson +16 more
2023Regular and Young Investigator Award Abstracts2 citations Open access
Semantic Scholar
Macrophages Activation By ICAM1 Antibody Combined With Lenalidomide Has Enhanced Anti-Myeloma Activity In a Supportive Microenvironment In Vivo and In Vitro
S. U. Venkateshaiah, Rakesh Bam, Xin Li, K. Sharmin +6 more
20132 citations
Semantic Scholar
Antibody binding geometry and affinity control inhibitory hFcγRIIB receptor signaling.
Hayden Fisher, Emma J Sutton, Robert J. Oldham, Richard T. Bradshaw +23 more
2026Immunity1 citations Open access
Semantic Scholar
A “Function-First” Approach to Identify Regulatory T cell–Targeting Antibodies for Immunotherapy
Kirstie L. S. Cleary, M. Semmrich, L. Mårtensson, Ulla-Carin Tornberg +17 more
2025Cancer immunology research1 citations
Semantic Scholar
Abstract 3567: Comprehensive preclinical studies of BT-001: An oncolytic vaccinia virus armed with Treg-depleting @CTLA4 and GM-CSF
Jean-Baptiste Marchand, M. Semmrich, C. Ziller, M. Rehn +12 more
2022Cancer Research1 citations
Semantic Scholar
Targeting Antibody Checkpoint Fcgriib Using Monoclonal Antibody BI-1206 to Overcome Therapeutic Resistance in Mantle Cell Lymphoma
Alexa A. Jordan, J. McIntosh, Yang Liu, Angela Leeming +8 more
20201 citations
Semantic Scholar
BI-1206, a Monoclonal Antibody Against Fcγriib, Showed Superior Anti-Tumor Activity in an Ibrutinib-Venetoclax Dual Resistant PDX Model in Mantle Cell Lymphoma
Chang-Ying Jiang, Yang Liu, J. McIntosh, Angela Leeming +9 more
2019Blood1 citations Open access
Semantic Scholar
PHASE 1/2A CLINICAL TRIALS OF BI‐1206, A MONOCLONAL ANTIBODY TO FCΓRIIB, ADMINISTERED AS A SINGLE AGENT OR IN COMBINATION WITH RITUXIMAB IN SUBJECTS WITH B‐CELL MALIGNANCIES
I. Karlsson, S. Traub, K. Järås, D. Edwards +13 more
2019Hematological Oncology1 citations
Semantic Scholar
Role of IFN-beta gene in the immune response after CpG motifs treatment in an allergy murine model
V. Matheu, A. Treschow, I. Teige, Y. Barrios +1 more
20031 citations Open access
Semantic Scholar
Anti-TNFR2 antibody BI-1808 induces tumor regression and antitumor T cell immunity through T reg and myeloid cell modulation in patients with solid tumors.
I. Teige, K. Rohrberg, A. Carneiro, J. Yachnin +28 more
2026Clinical Cancer Research0 citations Open access
Semantic Scholar
Ligand-Blocking and Agonist Antibodies Targeting TNFR2 Use Distinct Modes of Action to Induce Antitumor Immunity
L. Mårtensson, P. Holmkvist, Kirstie L. S. Cleary, Carolin Svensson +20 more
2026Cancer Research0 citations Open access
Semantic Scholar
Tailored FcγR blockade enhances immune checkpoint therapy and overcomes resistance
Robert J. Oldham, L. Mårtensson, M. Semmrich, N. Yoosuf +12 more
2026Journal of experimental & clinical cancer research : CR0 citations Open access
Semantic Scholar

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