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D. Serruto · SciRah

Researcher profile · Semantic Scholar

D. Serruto

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D. Serruto — researcher profile on SciRah

h-index: 34
Works: 57
Citations: 6,073

Most-cited papers

A universal vaccine for serogroup B meningococcus.
M. Giuliani, J. Adu‐Bobie, M. Comanducci, B. Aricó +26 more
2006Proceedings of the National Academy of Sciences of the United States of America764 citations Open access
Semantic Scholar
Vaccination against Neisseria meningitidis Using Three Variants of the Lipoprotein GNA1870
V. Masignani, M. Comanducci, M. Giuliani, S. Bambini +13 more
2003Journal of Experimental Medicine448 citations Open access
Semantic Scholar
The role of vaccines in combatting antimicrobial resistance
F. Micoli, F. Bagnoli, R. Rappuoli, D. Serruto
2021Nature Reviews Microbiology412 citations Open access
Semantic Scholar
The new multicomponent vaccine against meningococcal serogroup B, 4CMenB: immunological, functional and structural characterization of the antigens
D. Serruto, M. Bottomley, S. Ram, M. Giuliani +1 more
2012Vaccine398 citations Open access
Semantic Scholar
Microbiology in the post-genomic era
D. Medini, D. Serruto, J. Parkhill, D. Relman +4 more
2008Nature Reviews Microbiology358 citations
Semantic Scholar
Qualitative and quantitative assessment of meningococcal antigens to evaluate the potential strain coverage of protein-based vaccines
J. Donnelly, D. Medini, G. Boccadifuoco, A. Biolchi +16 more
2010Proceedings of the National Academy of Sciences of the United States of America325 citations Open access
Semantic Scholar
Predicted strain coverage of a meningococcal multicomponent vaccine (4CMenB) in Europe: a qualitative and quantitative assessment.
U. Vogel, M. Taha, J. Vázquez, J. Findlow +32 more
2013Lancet. Infectious Diseases (Print)302 citations
Semantic Scholar
Multiple Factors Modulate Biofilm Formation by the Anaerobic Pathogen Clostridium difficile
Tanja Dapa, R. Leuzzi, Yen K. Ng, S. Baban +6 more
2012Journal of Bacteriology273 citations Open access
Semantic Scholar
Genomic characterization of non-O1, non-O139 Vibrio cholerae reveals genes for a type III secretion system.
M. Dziejman, D. Serruto, V. Tam, D. Sturtevant +10 more
2005Proceedings of the National Academy of Sciences of the United States of America218 citations Open access
Semantic Scholar
Neisseria meningitidis is structured in clades associated with restriction modification systems that modulate homologous recombination
S. Budroni, Emilio Siena, Julie C. Dunning Hotopp, Kate L. Seib +12 more
2011Proceedings of the National Academy of Sciences of the United States of America217 citations Open access
Semantic Scholar
A type III secretion system in Vibrio cholerae translocates a formin/spire hybrid-like actin nucleator to promote intestinal colonization.
V. Tam, D. Serruto, M. Dziejman, W. Brieher +1 more
2007Cell Host and Microbe173 citations Open access
Semantic Scholar
Transcriptome Analysis of Neisseria meningitidis in Human Whole Blood and Mutagenesis Studies Identify Virulence Factors Involved in Blood Survival
Hebert Echenique-Rivera, A. Muzzi, E. Del Tordello, Kate L. Seib +4 more
2011PLoS Pathogens155 citations Open access
Semantic Scholar
Post‐genomic vaccine development
D. Serruto, R. Rappuoli
2006FEBS Letters144 citations Open access
Semantic Scholar
Molecular mechanisms of complement evasion: learning from staphylococci and meningococci
D. Serruto, R. Rappuoli, M. Scarselli, P. Gros +1 more
2010Nature Reviews Microbiology141 citations
Semantic Scholar
Two years into reverse vaccinology.
J. Adu‐Bobie, B. Capecchi, D. Serruto, R. Rappuoli +1 more
2003Vaccine141 citations
Semantic Scholar
Factor H-Binding Protein Is Important for Meningococcal Survival in Human Whole Blood and Serum and in the Presence of the Antimicrobial Peptide LL-37
Kate L. Seib, D. Serruto, Francesca Oriente, Isabel Delany +5 more
2008Infection and Immunity126 citations Open access
Semantic Scholar
Neisseria meningitidis NhhA is a multifunctional trimeric autotransporter adhesin
M. Scarselli, D. Serruto, Paolo Montanari, B. Capecchi +5 more
2006Molecular Microbiology115 citations
Semantic Scholar
Neisseria meningitidis App, a new adhesin with autocatalytic serine protease activity
D. Serruto, J. Adu‐Bobie, M. Scarselli, D. Veggi +3 more
2003Molecular Microbiology113 citations Open access
Semantic Scholar
Measuring antigen-specific bactericidal responses to a multicomponent vaccine against serogroup B meningococcus.
M. Giuliani, A. Biolchi, D. Serruto, Francesca Ferlicca +5 more
2010Vaccine102 citations
Semantic Scholar
Staphylococcal Esx Proteins Modulate Apoptosis and Release of Intracellular Staphylococcus aureus during Infection in Epithelial Cells
Charalampia-Georgia Korea, G. Balsamo, Alfredo Pezzicoli, Christina Merakou +4 more
2014Infection and Immunity89 citations Open access
Semantic Scholar
Genome-based approaches to develop vaccines against bacterial pathogens.
D. Serruto, L. Serino, V. Masignani, M. Pizza
2009Vaccine86 citations
Semantic Scholar
The genome revolution in vaccine research.
B. Capecchi, D. Serruto, J. Adu‐Bobie, R. Rappuoli +1 more
2004Current Issues in Molecular Biology74 citations Open access
Semantic Scholar
Neisseria meningitidis NalP cleaves human complement C3, facilitating degradation of C3b and survival in human serum
E. Del Tordello, I. Vacca, S. Ram, R. Rappuoli +1 more
2013Proceedings of the National Academy of Sciences of the United States of America73 citations Open access
Semantic Scholar
The Hfq-Dependent Small Noncoding RNA NrrF Directly Mediates Fur-Dependent Positive Regulation of Succinate Dehydrogenase in Neisseria meningitidis
Matteo M. E. Metruccio, L. Fantappiè, D. Serruto, A. Muzzi +4 more
2008Journal of Bacteriology63 citations Open access
Semantic Scholar
Biotechnology and vaccines: application of functional genomics to Neisseria meningitidis and other bacterial pathogens.
D. Serruto, J. Adu‐Bobie, B. Capecchi, R. Rappuoli +2 more
2004Journal of Biotechnology63 citations
Semantic Scholar
Identification of a Novel Zinc Metalloprotease through a Global Analysis of Clostridium difficile Extracellular Proteins
Valeria Cafardi, M. Biagini, M. Martinelli, R. Leuzzi +6 more
2013PLoS ONE62 citations Open access
Semantic Scholar
Staphylococcus aureus FhuD2 is involved in the early phase of staphylococcal dissemination and generates protective immunity in mice.
R. Mishra, P. Mariotti, Luigi Fiaschi, S. Nosari +10 more
2012Journal of Infectious Diseases61 citations Open access
Semantic Scholar
Influence of sequence variability on bactericidal activity sera induced by Factor H binding protein variant 1.1.
B. Brunelli, E. Del Tordello, E. Palumbo, A. Biolchi +8 more
2011Vaccine53 citations
Semantic Scholar
HadA is an atypical new multifunctional trimeric coiled‐coil adhesin of Haemophilus influenzae biogroup aegyptius, which promotes entry into host cells
D. Serruto, T. Spadafina, M. Scarselli, S. Bambini +13 more
2009Cellular Microbiology46 citations Open access
Semantic Scholar
Structure of the C-terminal Domain of Neisseria Heparin Binding Antigen (NHBA), One of the Main Antigens of a Novel Vaccine against Neisseria meningitidis
V. Esposito, V. Musi, C. de Chiara, D. Veggi +5 more
2011Journal of Biological Chemistry44 citations Open access
Semantic Scholar
NarE: a novel ADP‐ribosyltransferase from Neisseria meningitidis
V. Masignani, E. Balducci, F. Di Marcello, S. Savino +10 more
2003Molecular Microbiology44 citations
Semantic Scholar
Neisserial Heparin Binding Antigen (NHBA) Contributes to the Adhesion of Neisseria meningitidis to Human Epithelial Cells
I. Vacca, E. Del Tordello, G. Gasperini, Alfredo Pezzicoli +12 more
2016PLoS ONE43 citations Open access
Semantic Scholar
A novel Hfq‐dependent sRNA that is under FNR control and is synthesized in oxygen limitation in Neisseria meningitidis
L. Fantappiè, Francesca Oriente, A. Muzzi, D. Serruto +2 more
2011Molecular Microbiology40 citations Open access
Semantic Scholar
Recombinant bacterial vaccines.
M. Unnikrishnan, R. Rappuoli, D. Serruto
2012Current Opinion in Immunology35 citations
Semantic Scholar
Self-Assembling Nanoparticles Usher in a New Era of Vaccine Design.
R. Rappuoli, D. Serruto
2019Cell33 citations Open access
Semantic Scholar
Streptococcus pyogenes SpyCEP Influences Host-Pathogen Interactions during Infection in a Murine Air Pouch Model
N. Chiappini, A. Seubert, J. Telford, G. Grandi +3 more
2012PLoS ONE33 citations Open access
Semantic Scholar
Global Transcriptome Analysis Reveals Small RNAs Affecting Neisseria meningitidis Bacteremia
L. Fagnocchi, S. Bottini, G. Golfieri, L. Fantappiè +9 more
2015PLoS ONE31 citations Open access
Semantic Scholar
Future challenges in the elimination of bacterial meningitis.
M. Bottomley, D. Serruto, M. A. Sáfadi, K. Klugman
2012Vaccine31 citations
Semantic Scholar
In silico identification of novel bacterial ADP-ribosyltransferases.
V. Masignani, E. Balducci, D. Serruto, D. Veggi +4 more
2004International Journal of Medical Microbiology30 citations
Semantic Scholar
Monocyte-activation test to reliably measure the pyrogenic content of a vaccine: An in vitro pyrogen test to overcome in vivo limitations.
S. Valentini, G. Santoro, Federica Baffetta, S. Franceschi +5 more
2019Vaccine28 citations
Semantic Scholar
Analysis of the Regulated Transcriptome of Neisseria meningitidis in Human Blood Using a Tiling Array
E. Del Tordello, S. Bottini, A. Muzzi, D. Serruto
2012Journal of Bacteriology28 citations Open access
Semantic Scholar
High coverage of diverse invasive meningococcal serogroup B strains by the 4-component vaccine 4CMenB in Australia, 2007–2011: Concordant predictions between MATS and genetic MATS
S. Tozer, H. Smith, D. Whiley, R. Borrow +10 more
2021Human Vaccines & Immunotherapeutics15 citations Open access
Semantic Scholar
A Naturally Occurring Single-Residue Mutation in the Translocator Domain of Neisseria meningitidis NhhA Affects Trimerization, Surface Localization, and Adhesive Capabilities
Hebert Echenique-Rivera, B. Brunelli, M. Scarselli, A. Taddei +3 more
2011Infection and Immunity13 citations Open access
Semantic Scholar
The signal peptide sequence of a lytic transglycosylase of Neisseria meningitidis is involved in regulation of gene expression.
D. Serruto, C. Galeotti
2004Microbiology10 citations Open access
Semantic Scholar
Meningococcus B: From Genome to Vaccine
D. Serruto, R. Rappuoli, M. Pizza
20059 citations
Semantic Scholar
Functional genomics studies of the human pathogen Neisseria meningitidis.
E. Del Tordello, D. Serruto
2013Briefings in Functional Genomics7 citations Open access
Semantic Scholar
Bacterial Genomes and Vaccine Design
Valeria Cafardi, J. Telford, D. Serruto
20136 citations
Semantic Scholar
The early clinical development of a multicomponent vaccine against meningococcal serogroup B
J. Wassil, E. D. G. McIntosh, D. Serruto, L. DeTora +2 more
20126 citations
Semantic Scholar
Neisseria meningitidis population is structured in phylogenetic clades , associated with restriction-modification systems that modulate the effect of homologous recombination
S. Budroni, Emilio Siena, Julie C. Dunning Hotopp, Kate L. Seib +12 more
20101 citations
Semantic Scholar
Chapter 2 Bacterial Genomes and Vaccine Design
Valeria Cafardi, J. Telford, D. Serruto
20180 citations
Semantic Scholar

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M. Comanducci×10
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M. Giuliani — researcher profile on SciRah

J. Adu‐Bobie×9

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A. Muzzi — researcher profile on SciRah

M. Scarselli×9

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V. Masignani×8

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E. Del Tordello — researcher profile on SciRah