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W. Mandemakers · SciRah

Researcher profile · Semantic Scholar

W. Mandemakers

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W. Mandemakers — researcher profile on SciRah

h-index: 29
Works: 64
Citations: 5,783

Most-cited papers

Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/β-secretase expression
Sébastien S. Hébert, Katrien Horré, Laura Nicolaï, A. Papadopoulou +5 more
2008Proceedings of the National Academy of Sciences of the United States of America1,203 citations Open access
Semantic Scholar
Parkinson's disease mutations in PINK1 result in decreased Complex I activity and deficient synaptic function
V. Morais, Patrik Verstreken, A. Roethig, J. Smet +10 more
2009EMBO Molecular Medicine446 citations Open access
Semantic Scholar
LRRK2 controls an EndoA phosphorylation cycle in synaptic endocytosis.
S. Matta, K. Van Kolen, Raquel Ferro Da Cunha, G. van den Bogaart +17 more
2012Neuron357 citations Open access
Semantic Scholar
The deubiquitinase USP15 antagonizes Parkin-mediated mitochondrial ubiquitination and mitophagy
Tom Cornelissen, D. Haddad, Fieke Wauters, Cindy Van Humbeeck +7 more
2014Human Molecular Genetics329 citations Open access
Semantic Scholar
The POU proteins Brn-2 and Oct-6 share important functions in Schwann cell development.
M. Jaegle, M. Ghazvini, W. Mandemakers, M. Piirsoo +5 more
2003Genes & Development315 citations Open access
Semantic Scholar
The POU Factor Oct-6 and Schwann Cell Differentiation
M. Jaegle, W. Mandemakers, L. Broos, R. Zwart +4 more
1996Science308 citations
Semantic Scholar
Parkin Interacts with Ambra1 to Induce Mitophagy
Cindy Van Humbeeck, Tom Cornelissen, H. Hofkens, W. Mandemakers +3 more
2011Journal of Neuroscience279 citations Open access
Semantic Scholar
MicroRNAs in Alzheimer's disease.
C. Delay, W. Mandemakers, Sébastien S. Hébert
2012Neurobiology of Disease239 citations Open access
Semantic Scholar
The neurite outgrowth inhibitor Nogo A is involved in autoimmune-mediated demyelination
T. Karnezis, W. Mandemakers, J. McQualter, Bin-Hai Zheng +6 more
2004Nature Neuroscience237 citations
Semantic Scholar
The SAC1 domain in synaptojanin is required for autophagosome maturation at presynaptic terminals
Roeland Vanhauwaert, S. Kuenen, R. Masius, Adekunle T. Bademosi +17 more
2017EMBO Journal204 citations Open access
Semantic Scholar
An Oligodendrocyte Lineage-Specific Semaphorin, Sema5A, Inhibits Axon Growth by Retinal Ganglion Cells
J. Goldberg, M. E. Vargas, Jack T. Wang, W. Mandemakers +3 more
2004Journal of Neuroscience190 citations Open access
Semantic Scholar
A cell biological perspective on mitochondrial dysfunction in Parkinson disease and other neurodegenerative diseases
W. Mandemakers, V. Morais, B. de Strooper
2007Journal of Cell Science188 citations Open access
Semantic Scholar
DNAJC6 Mutations Associated With Early‐Onset Parkinson's Disease
S. Olgiati, M. Quadri, M. Fang, Janneke P. M. A. Rood +17 more
2016Annals of Neurology178 citations Open access
Semantic Scholar
LRRK2 functions in synaptic vesicle endocytosis through a kinase-dependent mechanism
Amaia M. Arranz, Lore Delbroek, K. Van Kolen, M. R. Guimarães +12 more
2015Journal of Cell Science160 citations
Semantic Scholar
LRP10 genetic variants in familial Parkinson's disease and dementia with Lewy bodies: a genome-wide linkage and sequencing study.
M. Quadri, W. Mandemakers, Martyna M. Grochowska, R. Masius +2 more
2018Lancet Neurology120 citations Open access
Semantic Scholar
A Novel Purification Method for CNS Projection Neurons Leads to the Identification of Brain Vascular Cells As a Source of Trophic Support for Corticospinal Motor Neurons
Jason C. Dugas, W. Mandemakers, M. Rogers, Adilijan Ibrahim +2 more
2008Journal of Neuroscience105 citations Open access
Semantic Scholar
Parkinson’s disease protein DJ-1 regulates ATP synthase protein components to increase neuronal process outgrowth
Rong-Min Chen, Han-A Park, N. Mnatsakanyan, Yu-Long Niu +12 more
2019Cell Death and Disease90 citations Open access
Semantic Scholar
The lipid sulfatide is a novel myelin-associated inhibitor of CNS axon outgrowth
Alissa Winzeler, W. Mandemakers, Matthew Z. Sun, M. Stafford +2 more
2011Journal of Neuroscience87 citations Open access
Semantic Scholar
Functional dissection of the Oct6 Schwann cell enhancer reveals an essential role for dimeric Sox10 binding
Noorjahan B. Jagalur, M. Ghazvini, W. Mandemakers, Siska Driegen +6 more
2011Journal of Neuroscience81 citations Open access
Semantic Scholar
A cell type‐specific allele of the POU gene Oct‐6 reveals Schwann cell autonomous function in nerve development and regeneration
Merhnaz Ghazvini, W. Mandemakers, M. Jaegle, M. Piirsoo +5 more
2002EMBO Journal69 citations Open access
Semantic Scholar
Paroxysmal exercise‐induced dystonia within the phenotypic spectrum of ECHS1 deficiency
S. Olgiati, M. Škorvánek, M. Quadri, Michelle Minneboo +23 more
2016Movement Disorders68 citations
Semantic Scholar
Deficiency of the miR-29a/b-1 cluster leads to ataxic features and cerebellar alterations in mice.
A. Papadopoulou, L. Serneels, T. Achsel, W. Mandemakers +13 more
2015Neurobiology of Disease60 citations Open access
Semantic Scholar
A distal Schwann cell‐specific enhancer mediates axonal regulation of the Oct‐6 transcription factor during peripheral nerve development and regeneration
W. Mandemakers, R. Zwart, M. Jaegle, E. Walbeehm +3 more
2000EMBO Journal60 citations Open access
Semantic Scholar
EIF2AK2 Missense Variants Associated with Early Onset Generalized Dystonia
Demy J. S. Kuipers, W. Mandemakers, C. Lu, S. Olgiati +30 more
2020Annals of Neurology58 citations Open access
Semantic Scholar
LRRK2 expression is enriched in the striosomal compartment of mouse striatum.
W. Mandemakers, An Snellinx, M. O'Neill, B. de Strooper
2012Neurobiology of Disease56 citations Open access
Semantic Scholar
Co-regulation of intragenic microRNA miR-153 and its host gene Ia-2β: identification of miR-153 target genes with functions related to IA-2β in pancreas and brain
W. Mandemakers, Liron Abuhatzira, Huan-Yu Xu, L. Caromile +7 more
2013Diabetologia46 citations Open access
Semantic Scholar
Gene and MicroRNA Transcriptome Analysis of Parkinson's Related LRRK2 Mouse Models
Véronique G. Dorval, W. Mandemakers, Francis Jolivette, L. Coudert +3 more
2014PLoS ONE43 citations Open access
Semantic Scholar
Axon regeneration: it's getting crowded at the gates of TROY.
W. Mandemakers, B. Barres
2005Current Biology34 citations Open access
Semantic Scholar
Comparison of sequence and function of the Oct-6 genes in zebrafish, chicken and mouse.
F. Levavasseur, W. Mandemakers, Pim Visser, L. Broos +3 more
1998Mechanisms of Development33 citations Open access
Semantic Scholar
PTPA variants and impaired PP2A activity in early-onset parkinsonism with intellectual disability
C. Fevga, C. Tesson, Ana Carreras Mascaro, T. Courtin +22 more
2022Brain : a journal of neurology27 citations Open access
Semantic Scholar
Development of an enzyme-linked immunosorbent assay for detection of cellular and in vivo LRRK2 S935 phosphorylation.
Lore Delbroek, K. Van Kolen, Liesbeth Steegmans, Raquel Ferro Da Cunha +9 more
2013Journal of Pharmaceutical and Biomedical Analysis26 citations Open access
Semantic Scholar
WARS2 mutations cause dopa-responsive early-onset parkinsonism and progressive myoclonus ataxia.
M. Škorvánek, I. Rektorová, W. Mandemakers, M. Wagner +22 more
2021Parkinsonism & Related Disorders24 citations Open access
Semantic Scholar
LRP10 interacts with SORL1 in the intracellular vesicle trafficking pathway in non-neuronal brain cells and localises to Lewy bodies in Parkinson’s disease and dementia with Lewy bodies
Martyna M. Grochowska, Ana Carreras Mascaro, Valerie Boumeester, Domenico Natale +12 more
2021Acta Neuropathologica20 citations Open access
Semantic Scholar
TMEM230: How does it fit in the etiology and pathogenesis of Parkinson's disease?
W. Mandemakers, M. Quadri, M. Stamelou, V. Bonifati
2017Movement Disorders12 citations
Semantic Scholar
Pervasive glycative stress links metabolic imbalance and muscle atrophy in early-onset Parkinson's disease
Natalia Prudente de Mello, Michelle T. Berger, K. Lagerborg, Yingfei Yan +24 more
2025Molecular Metabolism5 citations Open access
Semantic Scholar
LRP10 and α-synuclein transmission in Lewy body diseases
Ana Carreras Mascaro, Martyna M. Grochowska, Valerie Boumeester, N. Dits +7 more
2024Cellular and Molecular Life Sciences4 citations Open access
Semantic Scholar
Immunopanning of retrograde-labeled corticospinal motor neurons from early postnatal rodents.
W. Mandemakers
2014Cold Spring Harbor Protocols4 citations
Semantic Scholar
Generation and characterization of a genetic Parkinson's disease-patient derived iPSC line DJ-1-delP (LCSBi008-A).
Paul D. Mencke, I. Boussaad, G. Önal, A. Kievit +4 more
2022Stem Cell Research3 citations Open access
Semantic Scholar
LRP10 in α-synucleinopathies - Authors' reply.
M. Quadri, W. Mandemakers, Demy J. S. Kuipers, G. Breedveld +1 more
2018Lancet Neurology3 citations Open access
Semantic Scholar
DNAJC6 mutations associated with early-onset Parkinson's disease
S. Olgiati, M. Quadri, M. Fang, Janneke P. M. A. Rood +17 more
20163 citations
Semantic Scholar
Reply to Letter by Dr. Elsayed and colleagues
S. Olgiati, M. Quadri, W. Mandemakers, V. Bonifati
20153 citations
Semantic Scholar
CRISPR/Cas9-mediated LRP10 Knockout in HuTu-80 and HEK 293T Cell Lines.
Martyna M. Grochowska, V. Bonifati, W. Mandemakers
2022Bio-protocol2 citations Open access
Semantic Scholar
Generation of isogenic control DJ-1-delP GC13 for the genetic Parkinson's disease-patient derived iPSC line DJ-1-delP (LCSBi008-A-1).
Paul D. Mencke, Zoé Hanss, J. Jarazo, F. Massart +8 more
2022Stem Cell Research2 citations Open access
Semantic Scholar
Purification and culture of corticospinal motor neurons.
W. Mandemakers
2014Cold Spring Harbor Protocols2 citations
Semantic Scholar
Retrograde labeling of corticospinal motor neurons from early postnatal rodents.
W. Mandemakers
2014Cold Spring Harbor Protocols2 citations
Semantic Scholar
microRNAs in Sporadic Alzheimer’s Disease and Related Dementias
Sébastien S. Hébert, W. Mandemakers, A. Papadopoulou, B. Destrooper
20102 citations
Semantic Scholar
deCLUTTER2+ – a pipeline to analyze calcium traces in a stem cell model for ventral midbrain patterned astrocytes
Martyna M. Grochowska, F. Ferraro, Ana Carreras Mascaro, Domenico Natale +5 more
2023Disease Models & Mechanisms1 citations Open access
Semantic Scholar
Reply
S. Olgiati, M. Quadri, W. Mandemakers, V. Bonifati
2016Annals of Neurology1 citations
Semantic Scholar
Interactome mapping reveals a role for LRP10 in autophagy and NDFIP1-mediated α-synuclein secretion
Ana Carreras Mascaro, F. Ferraro, Valerie Boumeester, Guido J. Breedveld +6 more
2023bioRxiv0 citations Open access
Semantic Scholar
LRP10 as a novel α-synuclein regulator in Lewy body diseases
Ana Carreras Mascaro, Martyna M. Grochowska, Valerie Boumeester, N. Dits +7 more
2023bioRxiv0 citations Open access
Semantic Scholar

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