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C. Alper · SciRah

Researcher profile · Semantic Scholar

C. Alper

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C. Alper — researcher profile on SciRah

h-index: 44
Works: 191
Citations: 7,235

Most-cited papers

Genetic prediction of nonresponse to hepatitis B vaccine.
C. Alper, M. Kruskall, D. Marcus-Bagley, D. Craven +5 more
1989New England Journal of Medicine394 citations
Semantic Scholar
HLA-DQB1*0602 Is Associated With Dominant Protection From Diabetes Even Among Islet Cell Antibody–Positive First-Degree Relatives of Patients with IDDM
A. Pugliese, R. Gianani, Rocio Moromisato, Z. Awdeh +4 more
1995Diabetes205 citations
Semantic Scholar
Inheritable variable sizes of DNA stretches in the human MHC: conserved extended haplotypes and their fragments or blocks.
E. Yunis, C. Larsen, M. Fernández-Viña, Z. Awdeh +3 more
2003Tissue Antigens175 citations
Semantic Scholar
Prognostically Significant Heterogeneity of Cytoplasmic Islet Cell Antibodies in Relatives of Patients with Type I Diabetes
R. Gianani, A. Pugliese, S. Bonner-Weir, Alicia J Shiffrin +6 more
1992Diabetes131 citations
Semantic Scholar
The cellular basis for lack of antibody response to hepatitis B vaccine in humans
Eduardo Egea, A. Iglesias, M. Salazar, Chika Morimoto +5 more
1991Journal of Experimental Medicine131 citations Open access
Semantic Scholar
Major histocompatibility complex genes and susceptibility to systemic lupus erythematosus.
Z. Fronek, L. Timmerman, C. Alper, B. Hahn +3 more
1990Arthritis & Rheumatism109 citations
Semantic Scholar
The haplotype structure of the human major histocompatibility complex.
C. Alper, C. Larsen, D. Dubey, Z. Awdeh +2 more
2006Human Immunology103 citations
Semantic Scholar
The genetics of HLA-associated disease.
C. Larsen, C. Alper
2004Current Opinion in Immunology99 citations
Semantic Scholar
Circulating CD2+ monocytes are dendritic cells.
K. Crawford, D. Gabuzda, Vassilios Pantazopoulos, Jianhua Xu +3 more
1999Journal of Immunology88 citations Open access
Semantic Scholar
Implication of Specific DQB1 Alleles in Genetic Susceptibility and Resistance by Identification of IDDM Siblings With Novel HLA-DQB1 Allele and Unusual DR2 and DR1 Haplotypes
H. Erlich, R. L. Griffith, T. Bugawan, R. Ziegler +2 more
1991Diabetes80 citations
Semantic Scholar
Monoclonal and oligoclonal gammopathy after bone marrow transplantation.
Anna J. Mitus, Rosanne Stein, Joel M. Rappeport, Joseph H. Antin +3 more
1989Blood76 citations Open access
Semantic Scholar
Specific Association of HLA-DR4 With Increased Prevalence and Level of Insulin Autoantibodies in First-Degree Relatives of Patients With Type I Diabetes
R. Ziegler, C. Alper, Z. Awdeh, L. Castaňo +4 more
1991Diabetes74 citations
Semantic Scholar
Host-pathogen interactions in emerging and re-emerging infectious diseases: a genomic perspective of tuberculosis, malaria, human immunodeficiency virus infection, hepatitis B, and cholera.
J. Mcnicholl, M. Downer, V. Udhayakumar, C. Alper +1 more
2000Annual Review of Public Health73 citations Open access
Semantic Scholar
The effect of ethnicity on major histocompatibility complex complement allotypes and extended haplotypes in patients with systemic lupus erythematosus.
P. Schur, D. Marcus-Bagley, Z. Awdeh, E. Yunis +1 more
1990Arthritis & Rheumatism73 citations
Semantic Scholar
MHC class II alleles and haplotypes in patients with pemphigus vulgaris from India.
J. Delgado, D. Yunis, M. Bozon, M. Salazar +11 more
1996Tissue Antigens55 citations
Semantic Scholar
Conserved extended haplotypes discriminate HLA-DR3-homozygous Basque patients with type 1 diabetes mellitus and celiac disease
J. Bilbao, B. Calvo, A. Aransay, A. Martín-Pagola +10 more
2006Genes and Immunity54 citations
Semantic Scholar
Identical MHC markers in non-Jewish Iranian and Ashkenazi Jewish patients with pemphigus vulgaris: possible common central Asian ancestral origin.
N. Mobini, E. Yunis, C. Alper, J. Yunis +7 more
1997Human Immunology54 citations
Semantic Scholar
A genetic explanation for the rising incidence of type 1 diabetes, a polygenic disease.
Z. Awdeh, E. Yunis, M. Audeh, D. Fici +3 more
2006Journal of Autoimmunity49 citations
Semantic Scholar
GENETIC PREDICTION OF NON-RESPONSE TO HEPATITIS B VACCINE
C. Alper
199049 citations Open access
Semantic Scholar
Normal HBsAg presentation and T-cell defect in the immune response of nonresponders
M. Salazar, H. Deulofeut, C. Granja, R. Deulofeut +5 more
2004Immunogenetics48 citations
Semantic Scholar
Immunoglobulin Deficiencies and Susceptibility to Infection Among Homozygotes and Heterozygotes for C2 Deficiency
C. Alper, Jianhua Xu, Katherine Cosmopoulos, B. Dolinski +8 more
2003Journal of Clinical Immunology46 citations
Semantic Scholar
Complex cytokine responses to hepatitis B surface antigen and tetanus toxoid in responders, nonresponders and subjects naive to hepatitis B surface antigen.
C. Larsen, Jian-Hua Xu, Susan Lee, D. Dubey +3 more
2000Vaccine44 citations
Semantic Scholar
Protective KIR-HLA interactions for HCV infection in intravenous drug users
J. Zúñiga, Viviana A. Romero, J. Azócar, Daniel Terreros +9 more
2009Molecular Immunology39 citations Open access
Semantic Scholar
Incomplete penetrance of susceptibility genes for MHC-determined immunoglobulin deficiencies in monozygotic twins discordant for type 1 diabetes.
C. Alper, Z. Husain, C. Larsen, D. Dubey +7 more
2006Journal of Autoimmunity39 citations Open access
Semantic Scholar
CD2 engagement induces dendritic cell activation: implications for immune surveillance and T-cell activation.
K. Crawford, Aleksandra Stark, Betsy Kitchens, Kerry Sternheim +8 more
2003Blood37 citations
Semantic Scholar
Two subsets of HLA-DQA1 alleles mark phenotypic variation in levels of insulin autoantibodies in first degree relatives at risk for insulin-dependent diabetes.
A. Pugliese, T. Bugawan, Rocio Moromisato, Z. Awdeh +4 more
1994Journal of Clinical Investigation36 citations Open access
Semantic Scholar
Increased Apoptosis of CD20+ IgA+ B Cells is the Basis for IgA Deficiency: The Molecular Mechanism for Correction In Vitro by IL-10 and CD40L
Z. Husain, N. Holodick, C. Day, Irma Szymanski +1 more
2006Journal of Clinical Immunology34 citations
Semantic Scholar
No Independent Association Between HSP70 Gene Polymorphism and IDDM
A. Pugliese, Z. Awdeh, A. Galluzzo, E. Yunis +2 more
1992Diabetes34 citations
Semantic Scholar
HLA-Cw7 Zygosity Affects the Size of a Subset of CD158b+ Natural Killer Cells
Z. Husain, E. Levitan, C. Larsen, N. Mirza +4 more
2004Journal of Clinical Immunology20 citations
Semantic Scholar
Linkage of familial dysalbuminemic hyperthyroxinemia to the albumin gene in a large Amish kindred.
R. Weiss, T. Sunthornthepvarakul, P. Angkeow, D. Marcus-Bagley +3 more
1995Journal of Clinical Endocrinology and Metabolism20 citations
Semantic Scholar
Frequent occurrence of conserved extended haplotypes (CEHs) in two Caucasian populations.
Á. Szilágyi, Z. Banlaki, É. Pozsonyi, E. Yunis +7 more
2010Molecular Immunology19 citations
Semantic Scholar
Dominant Sequences of Human Major Histocompatibility Complex Conserved Extended Haplotypes from HLA-DQA2 to DAXX
C. Larsen, Dennis R. Alford, Michael R Trautwein, Y. K. Jalloh +6 more
2014PLoS Genetics18 citations Open access
Semantic Scholar
Immunofixation Electrophoresis: A Technique for the Study of Protein Polymorphism
C. Alper, A. M. Johnson
1993Vox Sanguinis18 citations
Semantic Scholar
BF types and the mode of inheritance of insulin-dependent diabetes mellitus (IDDM)
D. Raum, Z. Awdeh, C. Alper
2005Immunogenetics17 citations
Semantic Scholar
Single Nucleotide Polymorphism Blocks and Haplotypes: Human MHC Block Diversity
E. Yunis, J. Zúñiga, C. Larsen, C. Alper +3 more
200615 citations
Semantic Scholar
Molecular analysis distinguishes two HLA-DR3-bearing major histocompatibility complex extended haplotypes
Mark Z. Wescott, Z. Awdeh, E. Yunis, C. Alper
2004Immunogenetics15 citations
Semantic Scholar
HLA-DQA1, DQB1 and DPB1 alleles on HLA-DQ2- and DQ9-carrying extended haplotypes.
J. Yunis, M. Salazar, M. B. Delgado, C. Alper +2 more
1993Tissue Antigens15 citations
Semantic Scholar
A restriction fragment of the C2 gene is a unique marker for C2 deficiency and the uncommon C2 allele C2*B (a marker for type 1 diabetes).
S. Simon, Z. Awdeh, R. Campbell, P. Ronco +4 more
1991Journal of Clinical Investigation15 citations Open access
Semantic Scholar
Mendelian inheritance of polygenic diseases: a hypothetical basis for increasing incidence.
Z. Awdeh, C. Alper
2005Medical Hypotheses14 citations
Semantic Scholar
HLA-Cw alleles associated with HLA extended haplotypes and C2 deficiency.
O. Clavijo, J. Delgado, Z. Awdeh, D. Fici +4 more
1998Tissue Antigens14 citations
Semantic Scholar
The MHC type 1 diabetes susceptibility gene is centromeric to HLA-DQB1.
Z. Husain, M. Kelly, G. Eisenbarth, A. Pugliese +3 more
2008Journal of Autoimmunity13 citations
Semantic Scholar
Quantitative variation of C4 variant proteins associated with many MHC haplotypes
L. Truedsson, Z. Awdeh, E. Yunis, S. Mrose +2 more
2006Immunogenetics13 citations
Semantic Scholar
Linkage disequilibrium of HLA-SB1 with the HLA-A1, B8, DR3, SCO1 and of HLA-SB4 with the HLA-A26, Bw38, Dw10, DR4, SC21 extended haplotypes
Yoshiki Matsui, S. Alosco, Z. Awdeh, R. Duquesnoy +4 more
2004Immunogenetics13 citations
Semantic Scholar
The [HLA-B18, F1C30, DR3] Conserved Extended Haplotype Carries a Susceptibility Gene for IgD Deficiency
B. Calvo, L. Castaño, D. Marcus-Bagley, D. Fici +2 more
2000Journal of Clinical Immunology13 citations
Semantic Scholar
HLA: The Major Histocompatibility Complex of Man
A. Johnson, C. Hurley, R. Hartzman, C. Alper +1 more
199113 citations
Semantic Scholar
A Simple Estimate of the General Population Frequency of the MHC Susceptibility Gene for Autoimmune Polygenic Disease
C. Alper, D. Dubey, E. Yunis, Z. Awdeh
2000Experimental and Clinical Immunogenetics12 citations
Semantic Scholar
Predictability of alloreactivity among unrelated individuals.
Z. Awdeh, C. Alper, D. Fici, E. Eynon +2 more
1992Tissue Antigens12 citations
Semantic Scholar
A History of Complement Genetics
C. Alper
1999Experimental and Clinical Immunogenetics11 citations
Semantic Scholar
A New Pedigree-Based SNP Haplotype Method for Genomic Polymorphism and Genetic Studies
Zareen Vadva, C. Larsen, Bennett E Propp, Michael R Trautwein +2 more
2019Cells9 citations Open access
Semantic Scholar
Pedigree-Defined Haplotypes and Their Applications to Genetic Studies.
C. Alper, C. Larsen
2017Methods in molecular biology9 citations
Semantic Scholar

Frequent co-authors

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Z. Awdeh×25
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Z. Awdeh — researcher profile on SciRah
E. Yunis×23
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E. Yunis — researcher profile on SciRah
C. Larsen×15
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C. Larsen — researcher profile on SciRah
G. Eisenbarth×8
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G. Eisenbarth — researcher profile on SciRah

×7

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D. Fici — researcher profile on SciRah

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A. Pugliese — researcher profile on SciRah

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D. Dubey — researcher profile on SciRah

D. Marcus-Bagley×5

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D. Marcus-Bagley — researcher profile on SciRah

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Z. Husain — researcher profile on SciRah

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R. Jackson — researcher profile on SciRah

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M. Salazar — researcher profile on SciRah

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S. Brink — researcher profile on SciRah