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R. Saffrich · SciRah

Researcher profile · Semantic Scholar

R. Saffrich

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R. Saffrich — researcher profile on SciRah

h-index: 45
Works: 122
Citations: 9,738

Most-cited papers

Nanotubular Highways for Intercellular Organelle Transport
A. Rustom, R. Saffrich, I. Marković, P. Walther +1 more
2004Science1,218 citations
Semantic Scholar
Replicative Senescence of Mesenchymal Stem Cells: A Continuous and Organized Process
W. Wagner, P. Horn, M. Castoldi, A. Diehlmann +7 more
2008PLoS ONE1,134 citations Open access
Semantic Scholar
Direct induction of cyclin D2 by Myc contributes to cell cycle progression and sequestration of p27
C. Bouchard, Katja Thieke, A. Maier, R. Saffrich +6 more
1999EMBO Journal558 citations Open access
Semantic Scholar
VEGF expression by mesenchymal stem cells contributes to angiogenesis in pancreatic carcinoma
BM Beckermann, G. Kallifatidis, A. Groth, D. Frommhold +14 more
2008British Journal of Cancer406 citations Open access
Semantic Scholar
Exp5 exports eEF1A via tRNA from nuclei and synergizes with other transport pathways to confine translation to the cytoplasm
M. Bohnsack, Kathrin Regener, B. Schwappach, R. Saffrich +3 more
2002EMBO Journal253 citations Open access
Semantic Scholar
Inhibition of αvβ3 Integrin Survival Signaling Enhances Antiangiogenic and Antitumor Effects of Radiotherapy
A. Abdollahi, D. Griggs, H. Zieher, A. Roth +8 more
2005Clinical Cancer Research201 citations Open access
Semantic Scholar
The heterogeneity of human mesenchymal stem cell preparations--evidence from simultaneous analysis of proteomes and transcriptomes.
W. Wagner, R. Feldmann, A. Seckinger, M. Maurer +9 more
2006Experimental Hematology200 citations Open access
Semantic Scholar
Trimodal cancer treatment: beneficial effects of combined antiangiogenesis, radiation, and chemotherapy.
P. Huber, M. Bischof, J. Jenne, S. Heiland +6 more
2005Cancer Research193 citations Open access
Semantic Scholar
Co-culture with mesenchymal stromal cells increases proliferation and maintenance of haematopoietic progenitor cells
T. Walenda, S. Bork, P. Horn, F. Wein +5 more
2009Journal of Cellular and Molecular Medicine173 citations Open access
Semantic Scholar
Standardization of Good Manufacturing Practice-compliant production of bone marrow-derived human mesenchymal stromal cells for immunotherapeutic applications.
P. Wuchter, K. Bieback, H. Schrezenmeier, M. Bornhäuser +18 more
2015Cytotherapy146 citations
Semantic Scholar
Effects of CTGF Blockade on Attenuation and Reversal of Radiation-Induced Pulmonary Fibrosis
S. Bickelhaupt, C. Erbel, C. Timke, U. Wirkner +16 more
2017Journal of the National Cancer Institute144 citations Open access
Semantic Scholar
A gallium-labeled DOTA-alpha-melanocyte- stimulating hormone analog for PET imaging of melanoma metastases.
S. Froidevaux, M. Calame-Christe, J. Schuhmacher, H. Tanner +3 more
2004Journal of Nuclear Medicine142 citations
Semantic Scholar
Induction of cyclin E–cdk2 kinase activity, E2F‐dependent transcription and cell growth by Myc are genetically separable events
R. Beier, A. Bürgin, A. Kiermaier, M. Fero +6 more
2000EMBO Journal124 citations Open access
Semantic Scholar
The DEXD/H‐box RNA helicase RHII/Gu is a co‐factor for c‐Jun‐activated transcription
J. Westermarck, C. Weiss, R. Saffrich, J. Kast +7 more
2002EMBO Journal123 citations Open access
Semantic Scholar
Adhesion of hematopoietic progenitor cells to human mesenchymal stem cells as a model for cell-cell interaction.
W. Wagner, F. Wein, C. Roderburg, R. Saffrich +7 more
2007Experimental Hematology122 citations Open access
Semantic Scholar
Complex Functions of AP-1 Transcription Factors in Differentiation and Survival of PC12 Cells
S. Leppä, M. Eriksson, R. Saffrich, W. Ansorge +1 more
2001Molecular and Cellular Biology101 citations Open access
Semantic Scholar
Inhibition of alpha(v)beta3 integrin survival signaling enhances antiangiogenic and antitumor effects of radiotherapy.
A. Abdollahi, D. Griggs, H. Zieher, A. Roth +8 more
2005Clinical Cancer Research99 citations
Semantic Scholar
Radio-resistant mesenchymal stem cells: mechanisms of resistance and potential implications for the clinic
N. Nicolay, R. Perez, R. Saffrich, P. Huber
2015OncoTarget95 citations Open access
Semantic Scholar
The role of junctional adhesion molecule‐C (JAM‐C) in oxidized LDL‐mediated leukocyte recruitment
Tanja Keiper, N. Al-Fakhri, E. Chavakis, Athanasios N. Athanasopoulos +9 more
2005The FASEB Journal95 citations Open access
Semantic Scholar
Hematopoietic Progenitor Cells and Cellular Microenvironment: Behavioral and Molecular Changes upon Interaction
W. Wagner, R. Saffrich, U. Wirkner, V. Eckstein +7 more
2005Stem Cells88 citations
Semantic Scholar
Human Mesenchymal Stromal Cells Regulate Initial Self‐Renewing Divisions of Hematopoietic Progenitor Cells by a β1‐Integrin‐Dependent Mechanism
S. Gottschling, R. Saffrich, A. Seckinger, U. Krause +3 more
2007Stem Cells85 citations
Semantic Scholar
Proinflammatory profile of autoimmune CD8+ T cells relies on increased LDHA activity and aerobic glycolysis.
M. Margarida Souto-Carneiro, K. Klika, Mónica T. Abreu, A. Meyer +11 more
2020Arthritis & Rheumatology82 citations Open access
Semantic Scholar
Nuclear Export of the Nonenveloped Parvovirus Virion Is Directed by an Unordered Protein Signal Exposed on the Capsid Surface
B. Maroto, N. Valle, R. Saffrich, J. Almendral
2004Journal of Virology82 citations Open access
Semantic Scholar
Induction of CD4+ T-cell anergy and apoptosis by activated human B cells.
T. Tretter, Ram Kumar Chowdary Venigalla, V. Eckstein, R. Saffrich +3 more
2008Blood81 citations Open access
Semantic Scholar
Mesenchymal stem cells retain their defining stem cell characteristics after exposure to ionizing radiation.
N. Nicolay, E. Sommer, Ramón López, U. Wirkner +6 more
2013International Journal of Radiation Oncology, Biology, Physics79 citations
Semantic Scholar
N-cadherin is expressed on human hematopoietic progenitor cells and mediates interaction with human mesenchymal stromal cells.
F. Wein, Larissa Pietsch, R. Saffrich, P. Wuchter +7 more
2010Stem Cell Research75 citations Open access
Semantic Scholar
Effect of Increased Lactate Dehydrogenase A Activity and Aerobic Glycolysis on the Proinflammatory Profile of Autoimmune CD8+ T Cells in Rheumatoid Arthritis
M. Souto‐Carneiro, K. Klika, Mónica T. Abreu, A. Meyer +11 more
202064 citations Open access
Semantic Scholar
MEGAP impedes cell migration via regulating actin and microtubule dynamics and focal complex formation.
Ying Yang, M. Marcello, V. Endris, R. Saffrich +4 more
2006Experimental Cell Research64 citations
Semantic Scholar
Cep63 recruits Cdk1 to the centrosome: implications for regulation of mitotic entry, centrosome amplification, and genome maintenance.
H. Löffler, Anne-Meike Fechter, Marc Matuszewska, R. Saffrich +6 more
2011Cancer Research60 citations Open access
Semantic Scholar
Adhesion of Human Hematopoietic Progenitor Cells to Mesenchymal Stromal Cells Involves CD44
W. Wagner, F. Wein, C. Roderburg, R. Saffrich +3 more
2007Cells Tissues Organs58 citations
Semantic Scholar
Improved lentiviral transduction of human mesenchymal stem cells for therapeutic intervention in pancreatic cancer
G. Kallifatidis, BM Beckermann, A. Groth, M. Schubert +18 more
2008Cancer Gene Therapy57 citations
Semantic Scholar
The Many Facets of SDF-1α, CXCR4 Agonists and Antagonists on Hematopoietic Progenitor Cells
Anne Faber, C. Roderburg, F. Wein, R. Saffrich +8 more
2007Journal of Biomedicine and Biotechnology50 citations Open access
Semantic Scholar
Targeting of the 22 kDa integral peroxisomal membrane protein
Birgit Pause, R. Saffrich, A. Hunziker, W. Ansorge +1 more
2000FEBS Letters47 citations
Semantic Scholar
Mesenchymal stem cells are sensitive to bleomycin treatment
N. Nicolay, A. Rühle, R. Perez, T. Trinh +6 more
2016Scientific Reports45 citations Open access
Semantic Scholar
Mesenchymal stem cells are resistant to carbon ion radiotherapy
N. Nicolay, Yingying Liang, R. Perez, T. Bostel +7 more
2014OncoTarget43 citations Open access
Semantic Scholar
Rapid lamellipodia formation in nerve growth factor‐stimulated PC12 cells is dependent on Rac and PI3K activity
Guido Posern, R. Saffrich, W. Ansorge, S. Feller
2000Journal of Cellular Physiology42 citations
Semantic Scholar
Human mesenchymal stem cells lose their functional properties after paclitaxel treatment
Franziska Münz, R. Lopez Perez, T. Trinh, S. Sisombath +6 more
2018Scientific Reports39 citations Open access
Semantic Scholar
RhoA Regulates Peroxisome Association to Microtubules and the Actin Cytoskeleton
L. Schollenberger, Thomas Gronemeyer, Christoph M. Huber, Dorothee Lay +7 more
2010PLoS ONE38 citations Open access
Semantic Scholar
Microcavity arrays as an in vitro model system of the bone marrow niche for hematopoietic stem cells
P. Wuchter, R. Saffrich, S. Giselbrecht, Cordula Nies +4 more
2016Cell and Tissue Research37 citations Open access
Semantic Scholar
Quantifying Adhesion Mechanisms and Dynamics of Human Hematopoietic Stem and Progenitor Cells
Alexandra Burk, C. Monzel, H. Yoshikawa, P. Wuchter +4 more
2015Scientific Reports37 citations Open access
Semantic Scholar
Mesenchymal stem cells maintain their defining stem cell characteristics after treatment with cisplatin
N. Nicolay, R. Perez, A. Rühle, T. Trinh +6 more
2016Scientific Reports36 citations Open access
Semantic Scholar
Characterization of hematopoietic stem cell subsets from patients with multiple myeloma after mobilization with plerixafor.
Isabel Taubert, R. Saffrich, Abraham Zepeda‐Moreno, I. Hellwig +4 more
2011Cytotherapy36 citations
Semantic Scholar
Heterogeneity of leukemia stem cell candidates at diagnosis of acute myeloid leukemia and their clinical significance.
D. Ran, M. Schubert, Isabel Taubert, V. Eckstein +7 more
2012Experimental Hematology35 citations Open access
Semantic Scholar
The Stromal Activity of Mesenchymal Stromal Cells
W. Wagner, R. Saffrich, A. Ho
2008Transfusion Medicine and Hemotherapy35 citations Open access
Semantic Scholar
PAMAM structure-based multifunctional fluorescent conjugates for improved fluorescent labelling of biomacromolecules.
C. Wängler, G. Moldenhauer, R. Saffrich, E. Knapp +6 more
2008Chemistry35 citations
Semantic Scholar
The current understanding of mesenchymal stem cells as potential attenuators of chemotherapy‐induced toxicity
A. Rühle, P. Huber, R. Saffrich, R. Lopez Perez +1 more
2018International Journal of Cancer34 citations Open access
Semantic Scholar
Evaluation of GMP-compliant culture media for in vitro expansion of human bone marrow mesenchymal stromal cells.
P. Wuchter, M. Vetter, R. Saffrich, A. Diehlmann +3 more
2016Experimental Hematology34 citations Open access
Semantic Scholar
DNA binding of USF is required for specific E-box dependent gene activation in vivo
A. Kiermaier, J. Gawn, L. Desbarats, R. Saffrich +4 more
1999Oncogene30 citations
Semantic Scholar
Receptor‐mediated regulation of peroxisomal motility in CHO and endothelial cells
Christoph M. Huber, R. Saffrich, W. Ansorge, Wilhelm W. Just
1999EMBO Journal28 citations Open access
Semantic Scholar
The Radiation Resistance of Human Multipotent Mesenchymal Stromal Cells Is Independent of Their Tissue of Origin.
A. Rühle, O. Xia, R. Perez, T. Trinh +7 more
2018International Journal of Radiation Oncology, Biology, Physics27 citations
Semantic Scholar

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