Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

J. Westermarck · SciRah

Researcher profile · Semantic Scholar

J. Westermarck

Share profile

J. Westermarck — researcher profile on SciRah

h-index: 53
Works: 190
Citations: 12K

Most-cited papers

The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer
S. Vervoort, S. A. Welsh, J. Devlin, E. Barbieri +29 more
2021Cell181 citations Open access
Semantic Scholar
Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription
Riina Kaukonen, Anja Mai, M. Georgiadou, Markku Saari +11 more
2016Nature Communications133 citations Open access
Semantic Scholar
PP2A inhibition is a druggable MEK inhibitor resistance mechanism in KRAS-mutant lung cancer cells
O. Kauko, Caitlin M. O'Connor, Evgeny Kulesskiy, Jaya Sangodkar +14 more
2018Science Translational Medicine131 citations Open access
Semantic Scholar
Non-genomic mechanisms of protein phosphatase 2A (PP2A) regulation in cancer.
O. Kauko, J. Westermarck
2018International Journal of Biochemistry and Cell Biology105 citations
Semantic Scholar
Oncoprotein CIP2A is stabilized via interaction with tumor suppressor PP2A/B56
Jiao Wang, Juha Okkeri, Karolina Pavic, Zhizhi Wang +7 more
2017EMBO Reports97 citations Open access
Semantic Scholar
Editor's Note: p38 Mitogen-activated Protein Kinase Pathway Suppresses Cell Survival by Inducing Dephosphorylation of Mitogen-activated Protein/Extracellular Signal-regulated Kinase Kinase1,2.
Song-Ping Li, M. Junttila, Jia-Huai Han, V. Kähäri +1 more
2020Cancer Research92 citations
Semantic Scholar
Druggable cancer phosphatases
J. Vainonen, M. Momeny, J. Westermarck
2021Science Translational Medicine90 citations
Semantic Scholar
CIP2A Causes Tau/APP Phosphorylation, Synaptopathy, and Memory Deficits in Alzheimer’s Disease
Yangping Shentu, Yu-Da Huo, Xiao-Long Feng, James P. Gilbert +11 more
2018Cell Reports85 citations Open access
Semantic Scholar
Thioridazine inhibits autophagy and sensitizes glioblastoma cells to temozolomide
Tor-Christian Johannessen, M. Hasan-Olive, Huaiyang Zhu, O. Denisova +16 more
2018International Journal of Cancer76 citations Open access
Semantic Scholar
Phosphoproteome and drug-response effects mediated by the three protein phosphatase 2A inhibitor proteins CIP2A, SET, and PME-1
O. Kauko, Susumu Y. Imanishi, Evgeny Kulesskiy, L. Yetukuri +16 more
2020Journal of Biological Chemistry57 citations Open access
Semantic Scholar
Direct Activation of Protein Phosphatase 2A (PP2A) by Tricyclic Sulfonamides Ameliorates Alzheimer’s Disease Pathogenesis in Cell and Animal Models
Hui Wei, Hui-liang Zhang, Xiao-Chuan Wang, Jia-Zhao Xie +9 more
2020Neurotherapeutics53 citations Open access
Semantic Scholar
Targeted therapies don't work for a reason; the neglected tumor suppressor phosphatase PP2A strikes back
J. Westermarck
2018The FEBS Journal53 citations
Semantic Scholar
Stimuli-responsive hybrid nanocarriers developed by controllable integration of hyperbranched PEI with mesoporous silica nanoparticles for sustained intracellular siRNA delivery
N. Prabhakar, Ji-Xi Zhang, D. Desai, Eudald Casals +4 more
2016International Journal of Nanomedicine53 citations Open access
Semantic Scholar
Regulation of protein phosphatase 2A (PP2A) tumor suppressor function by PME-1.
Amanpreet Kaur, J. Westermarck
2016Biochemical Society Transactions52 citations
Semantic Scholar
PP2A Inhibitor PME-1 Drives Kinase Inhibitor Resistance in Glioma Cells.
Amanpreet Kaur, O. Denisova, X. Qiao, M. Jumppanen +8 more
2016Cancer Research49 citations Open access
Semantic Scholar
Enhanced expression of MycN/CIP2A drives neural crest toward a neural stem cell-like fate: Implications for priming of neuroblastoma
L. Kerosuo, Pushpa Neppala, J. Hsin, S. Mohlin +5 more
2018Proceedings of the National Academy of Sciences of the United States of America46 citations Open access
Semantic Scholar
CIP2A interacts with TopBP1 and drives basal-like breast cancer tumorigenesis
A. Laine, S. Nagelli, Caroline C Farrington, Umar Butt +20 more
2021Cancer Research45 citations Open access
Semantic Scholar
UBR5 Is Coamplified with MYC in Breast Tumors and Encodes an Ubiquitin Ligase That Limits MYC-Dependent Apoptosis
X. Qiao, Y. Liu, M. L. Prada, Aravind K. Mohan +15 more
2020Cancer Research43 citations Open access
Semantic Scholar
Optimized design and analysis of preclinical intervention studies in vivo
T. D. Laajala, M. Jumppanen, R. Huhtaniemi, V. Fey +8 more
2016Scientific Reports43 citations Open access
Semantic Scholar
Structural mechanism for inhibition of PP2A-B56α and oncogenicity by CIP2A
Karolina Pavic, Nikhil Gupta, Judit Domènech Omella, R. Derua +18 more
2023Nature Communications34 citations Open access
Semantic Scholar
Inactivation of PP2A by a recurrent mutation drives resistance to MEK inhibitors
Caitlin M. O'Connor, D. Leonard, Danica D. Wiredja, Rita A. Avelar +15 more
2019Oncogene34 citations Open access
Semantic Scholar
PP2A Inactivation Mediated by PPP2R4 Haploinsufficiency Promotes Cancer Development.
W. Sents, B. Meeusen, P. Kalev, E. Radaelli +9 more
2017Cancer Research34 citations
Semantic Scholar
Monotherapy efficacy of blood–brain barrier permeable small molecule reactivators of protein phosphatase 2A in glioblastoma
J. Merisaari, O. Denisova, M. Doroszko, V. Le Joncour +9 more
2020Brain Communications32 citations Open access
Semantic Scholar
Piecing Together a Broken Tumor Suppressor Phosphatase for Cancer Therapy.
J. Westermarck, B. Neel
2020Cell28 citations Open access
Semantic Scholar
PWP1 Mediates Nutrient-Dependent Growth Control through Nucleolar Regulation of Ribosomal Gene Expression.
Ying Liu, Jaakko Mattila, S. Ventelä, Leena Yadav +8 more
2017Developmental Cell27 citations Open access
Semantic Scholar
Chk1 Inhibition Ameliorates Alzheimer’s Disease Pathogenesis and Cognitive Dysfunction Through CIP2A/PP2A Signaling
Wenting Hu, Zhuoqun Wang, Hui-liang Zhang, Y. Mahaman +12 more
2022Neurotherapeutics26 citations Open access
Semantic Scholar
DUSP6 inhibition overcomes neuregulin/HER3-driven therapy tolerance in HER2+ breast cancer
Majid Momeny, Mari Tienhaara, Mukund Sharma, D. Chakroborty +10 more
2024EMBO Molecular Medicine23 citations Open access
Semantic Scholar
CIP2A-promoted astrogliosis induces AD-like synaptic degeneration and cognitive deficits
Yangping Shentu, Wenting Hu, Qing Zhang, Yu-Da Huo +10 more
2018Neurobiology of Aging21 citations Open access
Semantic Scholar
CIP2A coordinates phosphosignaling, mitosis, and the DNA damage response.
S. Nagelli, J. Westermarck
2023Trends in Cancer20 citations Open access
Semantic Scholar
CIP2A Promotes T-Cell Activation and Immune Response to Listeria monocytogenes Infection
C. Côme, Anna N. Cvrljevic, Mohd Moin Khan, Irina Treise +20 more
2016PLoS ONE20 citations Open access
Semantic Scholar
Cisplatin overcomes radiotherapy resistance in OCT4-expressing head and neck squamous cell carcinoma.
J. Routila, X. Qiao, J. Weltner, J. Rantala +12 more
2022Oral Oncology19 citations Open access
Semantic Scholar
(2S, 4R)-4-[18F]Fluoroglutamine for In vivo PET Imaging of Glioma Xenografts in Mice: an Evaluation of Multiple Pharmacokinetic Models
M. Miner, H. Liljenbäck, J. Virta, J. Merisaari +4 more
2020Molecular Imaging and Biology19 citations Open access
Semantic Scholar
Relevance Rank Platform (RRP) for Functional Filtering of High Content Protein–Protein Interaction Data*
Yuba Raj Pokharel, J. Saarela, Agnieszka Szwajda, C. Rupp +8 more
2015Molecular & Cellular Proteomics18 citations Open access
Semantic Scholar
Protein phosphatase 2A (PP2A) inhibitor CIP2A indicates resistance to radiotherapy in rectal cancer
E. Birkman, A. Elzagheid, T. Jokilehto, Tuulia Avoranta +5 more
2018Cancer Medicine17 citations Open access
Semantic Scholar
Endogenous PP2A inhibitor CIP2A degradation by chaperone-mediated autophagy contributes to the antitumor effect of mitochondrial complex I inhibition.
R. Cazzoli, F. Romeo, I. Pallavicini, Sebastiano Peri +10 more
2023Cell Reports15 citations Open access
Semantic Scholar
Circumventing Drug Treatment? Intrinsic Lethal Effects of Polyethyleneimine (PEI)-Functionalized Nanoparticles on Glioblastoma Cells Cultured in Stem Cell Conditions
N. Prabhakar, J. Merisaari, V. Le Joncour, M. Peurla +5 more
2021Cancers15 citations Open access
Semantic Scholar
Arpp19 Promotes Myc and Cip2a Expression and Associates with Patient Relapse in Acute Myeloid Leukemia
Eleonora Mäkelä, E. Löyttyniemi, U. Salmenniemi, O. Kauko +4 more
2019Cancers15 citations Open access
Semantic Scholar
PP2A methylesterase PME‐1 suppresses anoikis and is associated with therapy relapse of PTEN ‐deficient prostate cancers
Anna Aakula, Aleksi Isomursu, C. Rupp, A. Erickson +15 more
2022Molecular Oncology14 citations Open access
Semantic Scholar
Discovery of a Novel CIP2A Variant (NOCIVA) with Clinical Relevance in Predicting TKI Resistance in Myeloid Leukemias
Eleonora Mäkelä, Karolina Pavic, Taru Varila, U. Salmenniemi +10 more
2021Clinical Cancer Research14 citations Open access
Semantic Scholar
CIP2A Constrains Th17 Differentiation by Modulating STAT3 Signaling
Mohd Moin Khan, Ubaid Ullah, M. H. Khan, Ling-Jia Kong +9 more
2020iScience14 citations Open access
Semantic Scholar
Genistein Decreases APP/tau Phosphorylation and Ameliorates Aβ Over- production Through Inhibiting CIP2A.
Yangping Shentu, Wenting Hu, Jia-wei Liang, Zhen-yu Liuyang +6 more
2019Current Alzheimer Research14 citations
Semantic Scholar
Evaluation of prognostic biomarkers in a population-validated Finnish HNSCC patient cohort
J. Routila, I. Leivo, H. Minn, J. Westermarck +1 more
2021European Archives of Oto-Rhino-Laryngology12 citations Open access
Semantic Scholar
Good Guy in Bad Company: How STRNs Convert PP2A into an Oncoprotein.
K. Kurppa, J. Westermarck
2020Cancer Cell12 citations Open access
Semantic Scholar
Inhibition of adaptive therapy tolerance in cancer: is triplet mitochondrial targeting the key?
J. Westermarck
2023Molecular Oncology11 citations Open access
Semantic Scholar
Cancer cell line microarray as a novel screening method for identification of radioresistance biomarkers in head and neck squamous cell carcinoma
J. Routila, K. Suvila, R. Grénman, I. Leivo +2 more
2021BMC Cancer10 citations Open access
Semantic Scholar
Copy number increase of oncoprotein CIP2A is associated with poor patient survival in human head and neck squamous cell carcinoma.
J. Routila, T. Bilgen, O. Saramäki, R. Grénman +3 more
2016Journal of Oral Pathology & Medicine10 citations
Semantic Scholar
RAS and PP2A activities converge on epigenetic gene regulation
Anna Aakula, Mukund Sharma, Francesco Tabaro, R. Nätkin +6 more
2023Life Science Alliance9 citations Open access
Semantic Scholar
PP2A‐based triple‐strike therapy overcomes mitochondrial apoptosis resistance in brain cancer cells
O. Denisova, J. Merisaari, R. Huhtaniemi, X. Qiao +12 more
2023Molecular Oncology8 citations Open access
Semantic Scholar
Rules for PP2A-controlled phosphosignalling and drug responses
O. Kauko, Susumu Y. Imanishi, Evgeny Kulesskiy, T. D. Laajala +13 more
2018bioRxiv8 citations Open access
Semantic Scholar
Potential role for inhibition of protein phosphatase 2A tumor suppressor in salivary gland malignancies
J. Routila, Juho-Antti Mäkelä, Heikki Luukkaa, I. Leivo +4 more
2016Genes, Chromosomes and Cancer8 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

O. Kauko×11
Invite
O. Kauko — researcher profile on SciRah
T. Aittokallio×8
Invite
T. Aittokallio — researcher profile on SciRah
S. Ventelä×7
Invite
S. Ventelä — researcher profile on SciRah
Karolina Pavic×6
Invite
Karolina Pavic — researcher profile on SciRah

×6

Invite

T. D. Laajala — researcher profile on SciRah

K. Wennerberg×6

Invite

K. Wennerberg — researcher profile on SciRah

J. Merisaari×6

Invite

J. Merisaari — researcher profile on SciRah

Invite

M. Ohlmeyer — researcher profile on SciRah

Invite

Anna Aakula — researcher profile on SciRah

Invite

L. Yetukuri — researcher profile on SciRah

Invite

Taru Varila — researcher profile on SciRah

Jian-Zhi Wang×5

Invite

Jian-Zhi Wang — researcher profile on SciRah