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Y. Calle · SciRah

Researcher profile · Semantic Scholar

Y. Calle

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Y. Calle — researcher profile on SciRah

h-index: 24
Works: 66
Citations: 2,815

Most-cited papers

WIP Regulates the Stability and Localization of WASP to Podosomes in Migrating Dendritic Cells
H. Chou, I. Anton, M. Holt, C. Curcio +6 more
2006Current Biology421 citations Open access
Semantic Scholar
CRM1 inhibition induces tumor cell cytotoxicity and impairs osteoclastogenesis in multiple myeloma: molecular mechanisms and therapeutic implications
Yu-Tzu Tai, Y. Landesman, C. Acharya, Y. Calle +20 more
2013Leukemia304 citations Open access
Semantic Scholar
Two novel activating mutations in the Wiskott-Aldrich syndrome protein result in congenital neutropenia.
P. Ancliff, M. Blundell, G. Cory, Y. Calle +10 more
2006Blood227 citations
Semantic Scholar
Bruton tyrosine kinase inhibition is a novel therapeutic strategy targeting tumor in the bone marrow microenvironment in multiple myeloma.
Yu-Tzu Tai, B. Chang, Sun-Young Kong, M. Fulciniti +19 more
2012Blood173 citations Open access
Semantic Scholar
Unregulated actin polymerization by WASp causes defects of mitosis and cytokinesis in X-linked neutropenia
D. Moulding, M. Blundell, D. Spiller, M. White +8 more
2007Journal of Experimental Medicine167 citations Open access
Semantic Scholar
The leukocyte podosome.
Y. Calle, S. Burns, A. Thrasher, G. Jones
2006European Journal of Cell Biology154 citations
Semantic Scholar
Inhibition of calpain stabilises podosomes and impairs dendritic cell motility
Y. Calle, N. Carragher, A. Thrasher, G. Jones
2006Journal of Cell Science133 citations Open access
Semantic Scholar
WASp deficiency in mice results in failure to form osteoclast sealing zones and defects in bone resorption.
Y. Calle, G. Jones, C. Jagger, K. Fuller +4 more
2004Blood123 citations
Semantic Scholar
Wiskott–Aldrich syndrome protein and the cytoskeletal dynamics of dendritic cells
Y. Calle, H. Chou, A. Thrasher, G. Jones
2004Journal of Pathology105 citations Open access
Semantic Scholar
Evidence for a macromolecular complex in poor prognosis CLL that contains CD38, CD49d, CD44 and MMP‐9
A. Buggins, A. Levi, S. Gohil, K. Fishlock +4 more
2011British Journal of Haematology93 citations Open access
Semantic Scholar
Intracellular Staphylococcus aureus Modulates Host Central Carbon Metabolism To Activate Autophagy
Natalia Bravo-Santano, J. K. Ellis, Luís M. Mateos, Y. Calle +3 more
2018Msphere86 citations Open access
Semantic Scholar
Role of WASP in cell polarity and podosome dynamics of myeloid cells
J. Monypenny, H. Chou, I. Bañón-Rodríguez, A. Thrasher +3 more
2011European Journal of Cell Biology77 citations Open access
Semantic Scholar
Phosphorylation of WASp is a key regulator of activity and stability in vivo
M. Blundell, G. Bouma, J. Metelo, A. Worth +11 more
2009Proceedings of the National Academy of Sciences of the United States of America68 citations Open access
Semantic Scholar
Absence of mutations in cereblon (CRBN) and DNA damage-binding protein 1 (DDB1) genes and significance for IMiD therapy
A. Thakurta, A. Gandhi, Michelle F. Waldman, Chad C. Bjorklund +12 more
2013Leukemia56 citations Open access
Semantic Scholar
Epithelial Mesenchymal Transition (EMT) and Associated Invasive Adhesions in Solid and Haematological Tumours
D. Greaves, Y. Calle
2022Cells53 citations Open access
Semantic Scholar
WASP and WIP regulate podosomes in migrating leukocytes
Y. Calle, I. Anton, A. Thrasher, G. Jones
2008Journal of Microscopy50 citations
Semantic Scholar
Improvement of migratory defects in a murine model of Wiskott-Aldrich syndrome gene therapy.
M. Blundell, G. Bouma, Y. Calle, G. Jones +2 more
2008Molecular Therapy46 citations Open access
Semantic Scholar
Quantifying cell–matrix adhesion dynamics in living cells using interference reflection microscopy
M. Holt, Y. Calle, Deborah H. Sutton, D. Critchley +2 more
2008Journal of Microscopy46 citations
Semantic Scholar
The cortactin-binding domain of WIP is essential for podosome formation and extracellular matrix degradation by murine dendritic cells.
I. Bañón-Rodríguez, J. Monypenny, Chiara Ragazzini, A. Franco +3 more
2011European Journal of Cell Biology41 citations
Semantic Scholar
Host-directed kinase inhibitors act as novel therapies against intracellular Staphylococcus aureus
Natalia Bravo-Santano, Helen Stölting, F. Cooper, Narina Bileckaja +6 more
2019Scientific Reports31 citations Open access
Semantic Scholar
Indoxyl sulfate- and P-cresol-induced monocyte adhesion and migration is mediated by integrin-linked kinase-dependent podosome formation
S. Campillo, Lourdes Bohórquez, E. Gutiérrez-Calabrés, D. García-Ayuso +7 more
2022Experimental and Molecular Medicine27 citations Open access
Semantic Scholar
TIMP-2 secreted by monocyte-like cells is a potent suppressor of invadopodia formation in pancreatic cancer cells
C. Benzing, Hoyin Lam, Chi M. Tsang, Alexander Rimmer +3 more
2019BMC Cancer27 citations Open access
Semantic Scholar
Intracellular Staphylococcus aureus Elicits the Production of Host Very Long-Chain Saturated Fatty Acids with Antimicrobial Activity
Natalia Bravo-Santano, J. K. Ellis, Y. Calle, H. Keun +2 more
2019Metabolites25 citations Open access
Semantic Scholar
Tyrosine phosphorylation of WIP releases bound WASP and impairs podosome assembly in macrophages
V. Vijayakumar, J. Monypenny, Xing Judy Chen, L. Machesky +5 more
2015Journal of Cell Science24 citations Open access
Semantic Scholar
Tyrosine phosphorylation of WASP promotes calpain-mediated podosome disassembly
L. Macpherson, J. Monypenny, M. Blundell, G. Cory +4 more
2012Haematologica23 citations Open access
Semantic Scholar
Role of Cdc42 in neurite outgrowth of PC12 cells and cerebellar granule neurons
Ijaz Ahmed, Y. Calle, S. Iwashita, A. Nur‐e‐Kamal
2006Molecular and Cellular Biochemistry19 citations
Semantic Scholar
Cdc42-dependent nuclear translocation of non-receptor tyrosine kinase, ACK.
Ijaz Ahmed, Y. Calle, M. A. Sayed, J. Kamal +4 more
2004Biochemical and Biophysical Research Communications - BBRC19 citations
Semantic Scholar
Interleukin-2 increases intracellular glutathione levels and reverses the growth inhibiting effects of cyclophosphamide on B16 melanoma cells
T. Palomares, A. Alonso-Varona, A. Alvarez, B. Castro +2 more
1997Clinical and Experimental Metastasis19 citations
Semantic Scholar
PAK4 Kinase Activity Plays a Crucial Role in the Podosome Ring of Myeloid Cells
Elizabeth Foxall, Adela D. Staszowska, L. Hirvonen, M. Georgouli +8 more
2019Cell Reports18 citations Open access
Semantic Scholar
Fluorescence‐based experimental model to evaluate the concomitant effect of drugs on the tumour microenvironment and cancer cells
K. Ramasamy, H. Khatun, L. Macpherson, M. Caley +4 more
2012British Journal of Haematology17 citations
Semantic Scholar
Identification of novel targets for host-directed therapeutics against intracellular Staphylococcus aureus
Natalia Bravo-Santano, P. Capilla-Lasheras, Luís M. Mateos, Y. Calle +2 more
2019Scientific Reports16 citations Open access
Semantic Scholar
BCR–ABL1-induced downregulation of WASP in chronic myeloid leukemia involves epigenetic modification and contributes to malignancy
W. O. Pereira, D. D. De Carvalho, M. E. Zenteno, B. F. Ribeiro +9 more
2017Cell Death and Disease15 citations Open access
Semantic Scholar
Integrin linked kinase (ILK) regulates podosome maturation and stability in dendritic cells
M. Griera, Ester Martín-Villar, I. Bañón-Rodríguez, M. Blundell +5 more
2014International Journal of Biochemistry and Cell Biology15 citations Open access
Semantic Scholar
Effects of L‐2‐oxothiazolidine‐4‐carboxylate on the cytotoxic activity and toxicity of cyclophosphamide in mice bearing B16F10 melanoma liver metastases
M. del Olmo, A. Alonso-Varona, B. Castro, Y. Calle +2 more
2000Melanoma research15 citations
Semantic Scholar
In vitro and in vivo comparison between the effects of treatment with adenosine triphosphate and treatment with buthionine sulfoximine on chemosensitization and tumour growth of B16 melanoma.
T. Palomares, P. Bilbao, M. del Olmo, B. Castro +2 more
1999Melanoma research15 citations
Semantic Scholar
Tumor-host interaction in non-random metastatic pattern distribution.
A. Alonso-Varona, T. Palomares, P. Bilbao, Y. Calle +2 more
1996Bulletin du Cancer13 citations
Semantic Scholar
Tunicamycin Treatment Reduces Intracellular Glutathione Levels: Effect on the Metastatic Potential of the Rhabdomyosarcoma Cell Line S4MH
Y. Calle, T. Palomares, B. Castro, M. del Olmo +2 more
2000Chemotherapy11 citations
Semantic Scholar
Removal of N‐glycans from cell surface proteins induces apoptosis by reducing intracellular glutathione levels in the rhabdomyosarcoma cell line S4MH
Y. Calle, T. Palomares, B. Castro, M. Olmo +1 more
2000Biology of the Cell9 citations
Semantic Scholar
HOX genes and cell adhesion molecules in cancers.
A. Varona, B. Castro, Y. Calle, T. Palomares +4 more
1996International Journal of Developmental Biology6 citations
Semantic Scholar
Inhibition of PI3K Class IA Kinases Using GDC-0941 Overcomes Cytoprotection of Multiple Myeloma Cells in the Osteoclastic Bone Marrow Microenvironment Enhancing the Efficacy of Current Clinical Therapeutics
H. Kikuchi, Eunice Amofa, M. Mcenery, S. Schey +3 more
2023Cancers4 citations Open access
Semantic Scholar
PAK4 Kinase Activity Plays a Crucial Role in the Podosome Ring of Myeloid Cells
Elizabeth Foxall, Adela D. Staszowska, L. Hirvonen, M. Georgouli +8 more
2020Cell Reports4 citations Open access
Semantic Scholar
Plasticity in leukocyte migration during haematopoiesis and inflammation
C. Villella, M. Ciccioli, I. Anton, Y. Calle
2025Journal of Muscle Research and Cell Motility3 citations Open access
Semantic Scholar
Absence Of Mutation In Cereblon (CRBN) and DNA Damage Binding Protein 1 (DDB1) Genes In Myeloma Cells and Patients and Its Clinical Significance
A. Gandhi, Michelle F. Waldman, Chad C. Bjorklund, S. Lentzsch +11 more
20133 citations
Semantic Scholar
CRM1 Blockade by Novel Inhibitors of Nuclear Export (SINEs) Inhibits Multiple Myeloma Cell Growth, Osteoclastogenesis, and Myeloma-Induced Osteolysis
Yu-Tzu Tai, Y. Landesman, C. Acharya, M. Zhong +21 more
20122 citations
Semantic Scholar
Targeting Brouton's Tyrosine Kinase with PCI-32765 Blocks Growth and Survival of Multiple Myeloma and Waldenstrom Macroglobulinemia Via Potent Inhibition of Osteoclastogenesis, Cytokines/Chemokine Secretion, and Myeloma Stem-Like Cells in the Bone Marrow Microenvironment
Yu-Tzu Tai, B. Chang, Sun-Young Kong, M. Fulciniti +18 more
20112 citations
Semantic Scholar
Podia in Multiple Myeloma (MM) Cells Promote Adhesion with Bone Marrow (BM) Fibroblastic Stromal Cells
K. Ramasamy, Amna Anwar, M. Kazmi, S. Schey +1 more
20112 citations
Semantic Scholar
A simple cell labeling technique by means of lectins linked to fluorochromes for the detection of cells on tissue sections
A. Alonso-Varona, Y. Calle, T. Palomares, B. Castro +1 more
1995Biology of the Cell2 citations
Semantic Scholar
CRM1 Inhibition Abrogates Osteoclast Formation and Bone Resorption Via Inhibition of RANKL-Induced NFκB While Sparing Osteoblastogenesis: Further Therapeutic Implication in Multiple Myeloma
C. Acharya, M. Zhong, Y. Calle, S. Schey +9 more
20121 citations
Semantic Scholar
The Wiskott Aldrich Syndrome Protein (WASP) Is Involved in Dexamethasone-Signalling Pathways Leading to Apoptosis of Multiple Myeloma Cells and in Cell Adhesion Mediated Drug Resistance Against Dexamethasone
H. Khatun, Amna Anwar, M. Kazmi, S. Schey +1 more
20111 citations
Semantic Scholar
Direct Effect on the Stroma by the Conventional Anti-Multiple Myeloma Drug Dexamethasone Results In Resistance of Multiple Myeloma Plasma Cells Against Therapy. Sensitisation to Dexamethasone by the Kinase Inhibitor Dasatinib
K. Ramasamy, H. Khatun, L. Macpherson, G. Mufti +2 more
20101 citations
Semantic Scholar

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