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I. Yasinska · SciRah

Researcher profile · Semantic Scholar

I. Yasinska

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I. Yasinska — researcher profile on SciRah

h-index: 22
Works: 51
Citations: 1,838

Most-cited papers

The Tim-3-galectin-9 Secretory Pathway is Involved in the Immune Escape of Human Acute Myeloid Leukemia Cells
Isabel Gonçalves Silva, I. Yasinska, S. Sakhnevych, W. Fiedler +11 more
2017EBioMedicine218 citations Open access
Semantic Scholar
Gold nanoparticles downregulate interleukin-1β-induced pro-inflammatory responses.
V. Sumbayev, I. Yasinska, C. García, D. Gilliland +6 more
2013Small212 citations
Semantic Scholar
S‐nitrosation of Cys‐800 of HIF‐1α protein activates its interaction with p300 and stimulates its transcriptional activity
I. Yasinska, V. Sumbayev
2003FEBS Letters168 citations Open access
Semantic Scholar
The Tim-3-Galectin-9 Pathway and Its Regulatory Mechanisms in Human Breast Cancer
I. Yasinska, S. Sakhnevych, Ludmila Pavlova, Anette Teo Hansen Selnø +15 more
2019Frontiers in Immunology161 citations Open access
Semantic Scholar
Regulation of MAP kinase-dependent apoptotic pathway: implication of reactive oxygen and nitrogen species.
V. Sumbayev, I. Yasinska
2005Archives of Biochemistry and Biophysics123 citations
Semantic Scholar
Ligand-Receptor Interactions of Galectin-9 and VISTA Suppress Human T Lymphocyte Cytotoxic Activity
I. Yasinska, N. Meyer, S. Schlichtner, R. Hussain +12 more
2020Frontiers in Immunology100 citations Open access
Semantic Scholar
Role of MAP Kinase‐Dependent Apoptotic Pathway in Innate Immune Responses and Viral Infection
V. Sumbayev, I. Yasinska
2006Scandinavian Journal of Immunology76 citations Open access
Semantic Scholar
Involvement of xanthine oxidase and hypoxia-inducible factor 1 in Toll-like receptor 7/8-mediated activation of caspase 1 and interleukin-1β
Sally A. Nicholas, V. V. Bubnov, I. Yasinska, V. Sumbayev
2010Cellular and Molecular Life Sciences53 citations Open access
Semantic Scholar
Transforming growth factor beta type 1 (TGF-β) and hypoxia-inducible factor 1 (HIF-1) transcription complex as master regulators of the immunosuppressive protein galectin-9 expression in human cancer and embryonic cells
A. T. H. Selnø, S. Schlichtner, I. Yasinska, S. Sakhnevych +11 more
2020Aging52 citations Open access
Semantic Scholar
Involvement of Hypoxia-Inducible Factor-1 in the Inflammatory Responses of Human LAD2 Mast Cells and Basophils
V. Sumbayev, I. Yasinska, A. Oniku, C. Streatfield +1 more
2012PLoS ONE51 citations Open access
Semantic Scholar
T lymphocytes induce human cancer cells derived from solid malignant tumors to secrete galectin-9 which facilitates immunosuppression in cooperation with other immune checkpoint proteins
S. Schlichtner, I. Yasinska, G. Lall, Steffen M. Berger +6 more
2023Journal for ImmunoTherapy of Cancer45 citations Open access
Semantic Scholar
High mobility group box 1 (HMGB1) acts as an “alarmin” to promote acute myeloid leukaemia progression
I. Yasinska, Isabel Gonçalves Silva, S. Sakhnevych, Laura Ruegg +11 more
2018Oncoimmunology42 citations Open access
Semantic Scholar
Nitric oxide inhibits HIF-1alpha protein accumulation under hypoxic conditions: implication of 2-oxoglutarate and iron.
A. Kozhukhar, I. Yasinska, V. Sumbayev
2006Biochimie39 citations
Semantic Scholar
L-Kynurenine participates in cancer immune evasion by downregulating hypoxic signaling in T lymphocytes
S. Schlichtner, I. Yasinska, E. Klenova, Maryam Abooali +8 more
2023Oncoimmunology36 citations Open access
Semantic Scholar
S-nitrosation of thioredoxin in the nitrogen monoxide/superoxide system activates apoptosis signal-regulating kinase 1.
I. Yasinska, A. Kozhukhar, V. Sumbayev
2004Archives of Biochemistry and Biophysics35 citations
Semantic Scholar
Expression of the Immune Checkpoint Protein VISTA Is Differentially Regulated by the TGF-β1 – Smad3 Signaling Pathway in Rapidly Proliferating Human Cells and T Lymphocytes
S. Schlichtner, I. Yasinska, S. Ruggiero, Steffen M. Berger +7 more
2022Frontiers in Medicine30 citations Open access
Semantic Scholar
Microscopic Analysis of the Interaction of Gold Nanoparticles with Cells of the Innate Immune System
C. García, V. Sumbayev, D. Gilliland, I. Yasinska +4 more
2013Scientific Reports30 citations Open access
Semantic Scholar
High Mobility Group Box 1 (HMGB1) Induces Toll-Like Receptor 4-Mediated Production of the Immunosuppressive Protein Galectin-9 in Human Cancer Cells
Anette Teo Hansen Selnø, S. Schlichtner, I. Yasinska, S. Sakhnevych +7 more
2021Frontiers in Immunology28 citations Open access
Semantic Scholar
Mechanisms of hypoxic signal transduction regulated by reactive nitrogen species
V. Sumbayev, I. Yasinska
2007Scandinavian Journal of Immunology28 citations Open access
Semantic Scholar
Functional role of galectin-9 in directing human innate immune reactions to Gram-negative bacteria and T cell apoptosis.
S. Schlichtner, N. Meyer, I. Yasinska, Nijas Aliu +4 more
2021International Immunopharmacology26 citations Open access
Semantic Scholar
IgE‐mediated basophil tumour necrosis factor alpha induces matrix metalloproteinase‐9 from monocytes
S. Falkencrone, L. Poulsen, C. Bindslev-Jensen, A. Woetmann +8 more
2013Allergy. European Journal of Allergy and Clinical Immunology26 citations
Semantic Scholar
Effects of Stem Cell Factor on Hypoxia-Inducible Factor 1 Alpha Accumulation in Human Acute Myeloid Leukaemia and LAD2 Mast Cells
B. Gibbs, I. Yasinska, A. Oniku, V. Sumbayev
2011PLoS ONE24 citations Open access
Semantic Scholar
The HIF-1 transcription complex is essential for translational control of myeloid hematopoietic cell function by maintaining mTOR phosphorylation
I. Yasinska, B. Gibbs, G. Lall, V. Sumbayev
2013Cellular and Molecular Life Sciences21 citations Open access
Semantic Scholar
Caffeine affects the biological responses of human hematopoietic cells of myeloid lineage via downregulation of the mTOR pathway and xanthine oxidase activity
Bernhard F. Gibbs, I. G. Silva, A. Prokhorov, Maryam Abooali +5 more
2015OncoTarget20 citations Open access
Semantic Scholar
Dysfunctional mitochondria contain endogenous high-affinity human Toll-like receptor 4 (TLR4) ligands and induce TLR4-mediated inflammatory reactions.
Sally A. Nicholas, K. Coughlan, I. Yasinska, G. Lall +3 more
2011International Journal of Biochemistry and Cell Biology20 citations
Semantic Scholar
Biochemical mechanisms implemented by human acute myeloid leukemia cells to suppress host immune surveillance
I. Yasinska, Isabel Gonçalves Silva, S. Sakhnevych, B. Gibbs +3 more
2018Cellular & Molecular Immunology19 citations Open access
Semantic Scholar
Intracellular and extracellular activities of V-domain Ig-containing suppressor of T cell activation (VISTA) modulated by immunosuppressive factors of tumour microenvironment.
Maryam Abooali, S. Schlichtner, X. Lei, Nijas Aliu +25 more
2025Cancer Letters18 citations Open access
Semantic Scholar
Mitochondrial Defunctionalization Supresses Tim-3-Galectin-9 Secretory Pathway in Human Colorectal Cancer Cells and Thus Can Possibly Affect Tumor Immune Escape
S. Sakhnevych, I. Yasinska, E. Fasler-Kan, V. Sumbayev
2019Frontiers in Pharmacology16 citations Open access
Semantic Scholar
Expression of functional neuronal receptor latrophilin 1 in human acute myeloid leukaemia cells
V. Sumbayev, I. G. Silva, Jennifer K. Blackburn, B. Gibbs +4 more
2016OncoTarget16 citations Open access
Semantic Scholar
Peroxynitrite as an alternative donor of oxygen in HIF-1α proline hydroxylation under low oxygen availability
V. Sumbayev, I. Yasinska
2006Free radical research16 citations
Semantic Scholar
Highly specific targeting of human acute myeloid leukaemia cells using pharmacologically active nanoconjugates.
I. Yasinska, G. Ceccone, I. Ojea-Jiménez, J. Ponti +12 more
2018Nanoscale15 citations Open access
Semantic Scholar
Differential control of hypoxia-inducible factor 1 activity during pro-inflammatory reactions of human haematopoietic cells of myeloid lineage.
B. Gibbs, I. Yasinska, D. Pchejetski, Rafał Wyszyński +1 more
2012International Journal of Biochemistry and Cell Biology15 citations
Semantic Scholar
Targeting of Basophil and Mast Cell Pro-Allergic Reactivity Using Functionalised Gold Nanoparticles
I. Yasinska, L. Calzolai, U. Raap, R. Hussain +3 more
2019Frontiers in Pharmacology12 citations Open access
Semantic Scholar
Highly specific targeting of human leukocytes using gold nanoparticle-based biologically active conjugates.
B. Gibbs, I. Yasinska, L. Calzolai, D. Gilliland +1 more
2014Journal of Biomedical Nanotechnology11 citations
Semantic Scholar
Cortisol facilitates the immune escape of human acute myeloid leukemia cells by inducing latrophilin 1 expression
S. Sakhnevych, I. Yasinska, A. Bratt, Ouafa Benlaouer +8 more
2018Cellular & Molecular Immunology10 citations Open access
Semantic Scholar
Activation of immune evasion machinery is a part of the process of malignant transformation of human cells
Maryam Abooali, I. Yasinska, S. Schlichtner, S. Ruggiero +6 more
2023Translational Oncology9 citations Open access
Semantic Scholar
Protein S-nitrosation in signal transduction: assays for specific qualitative and quantitative analysis.
V. Sumbayev, I. Yasinska
2008Methods in Enzymology5 citations
Semantic Scholar
Wuhan strain of SARS-CoV-2 triggers activation of immune evasion machinery similar to the one operated by cancer cells
Maryam Abooali, I. Yasinska, G. Thapa, X. Lei +7 more
2025Frontiers in Immunology4 citations Open access
Semantic Scholar
Alliance of galectin-3 and CD74 biochemical networks as a crucial component of survival machinery operated by human acute myeloid leukaemia cells
I. Yasinska, V. Sumbayev
2019EBioMedicine3 citations Open access
Semantic Scholar
Ligand-receptor interactions of V-domain Ig-containing suppressor of T cell activation and programmed death-1 suppress the anticancer activities of T cells
M. Abooali, Le Xi, I. Yasinska, S. Schlichtner +8 more
2025Immuno-Oncology Technology2 citations Open access
Semantic Scholar
P01.17 Tim-3/Galectin-9 pathway controls the ability of malignant cells to escape host immune surveillance. Regulatory mechanisms and therapeutic targets
V. Sumbayev, I. Yasinska, SS Sakhnevych, E. Fasler-Kan +1 more
20202 citations Open access
Semantic Scholar
PO-409 Highly specific targeting of human acute myeloid leukaemia (AML) cells using functionalised gold nanoparticles
I. Yasinska, B. Gibbs, L. Varani, R. Hussain +4 more
2018ESMO Open1 citations Open access
Semantic Scholar
61 Hypoxia-Inducible Factor 1 (HIF-1) Transcription is a “Signalling Driver” for Allergic Inflammation, Host Innate Immune Defence and Leukaemia Progression
V. Sumbayev, I. Yasinska, B. Gibbs
2012The World Allergy Organization Journal1 citations Open access
Semantic Scholar
CD44-galectin-9 and TGF-β-Smad3 Pathways Form an Autocrine Loop which Facilitates Human Cancer Cells to Self-Regulate their Immune Evasion Machinery.
X. Lei, Si-Bo Peng, Nijas Aliu, R. Hussain +17 more
2026Cancer Letters0 citations Open access
Semantic Scholar
P01.07 Galectin 9 dependent immune evasion machinery as a potential target for personalised immunotherapy of cancer
V. Sumbayev, I. Yasinska, S. Schlichtner, G. Lall +2 more
2022Poster Presentations0 citations Open access
Semantic Scholar
Abstract A30: Targeting of the mTOR pathway in human acute myeloid leukemia cells using functionalized gold nanoparticles
I. Yasinska, B. Gibbs, L. Varani, R. Hussain +4 more
20200 citations
Semantic Scholar
PO-395 Cortisol triggers immune escape of human acute myeloid leukaemia cells by inducing expression of G protein-coupled receptor latrophilin 1 which facilitates exocytosis of immune suppressor galectin-9
Svetlana S. Sakhnevych, I. Yasinska, I. G. Silva, Y. Ushkaryov +2 more
2018ESMO Open0 citations Open access
Semantic Scholar
Physical and chemical properties of AuNPs
V. Sumbayev, I. Yasinska, B. Gibbs, Medway
20130 citations
Semantic Scholar
129 Involvement of the Hypoxia-Inducible Factor-1 Transcription Complex in the Inflammatory Responses of Human Mast Cells and Basophils
I. Yasinska, V. Sumbayev, B. Gibbs
2012The World Allergy Organization Journal0 citations Open access
Semantic Scholar
the biological responses of human hematopoietic cells of myeloid lineage via downregulation of the
Bernhard F. Gibbs, Isabel Gonçalves, A. Prokhorov, Maryam Abooali +5 more
0 citations
Semantic Scholar

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