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S. Thorpe · SciRah

Researcher profile · Semantic Scholar

S. Thorpe

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S. Thorpe — researcher profile on SciRah

h-index: 83
Works: 226
Citations: 29K

Most-cited papers

Effect of Collagen Turnover on the Accumulation of Advanced Glycation End Products*
N. Verzijl, J. DeGroot, S. Thorpe, Ruud A. Bank +6 more
2000Journal of Biological Chemistry905 citations Open access
Semantic Scholar
Simple non-invasive assessment of advanced glycation endproduct accumulation
R. Meerwaldt, R. Graaff, P. Oomen, T. Links +6 more
2004Diabetologia781 citations Open access
Semantic Scholar
Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging.
H. Van Remmen, Y. Ikeno, M. Hamilton, M. Pahlavani +9 more
2003Physiological Genomics762 citations
Semantic Scholar
Maillard reaction products in tissue proteins: New products and new perspectives
S. Thorpe, J. Baynes
2003Amino Acids553 citations
Semantic Scholar
Glycoxidation and lipoxidation in atherogenesis.
J. Baynes, S. Thorpe
2000Free Radical Biology & Medicine516 citations
Semantic Scholar
Crosslinking by advanced glycation end products increases the stiffness of the collagen network in human articular cartilage: a possible mechanism through which age is a risk factor for osteoarthritis.
N. Verzijl, J. DeGroot, Chaya Ben Zaken, Orit Braun-Benjamin +9 more
2002Arthritis & Rheumatism490 citations Open access
Semantic Scholar
Pyridoxamine inhibits early renal disease and dyslipidemia in the streptozotocin-diabetic rat.
T. Degenhardt, N. Alderson, D. D. Arrington, R. J. Beattie +4 more
2002Kidney International391 citations Open access
Semantic Scholar
Skin autofluorescence, a measure of cumulative metabolic stress and advanced glycation end products, predicts mortality in hemodialysis patients.
R. Meerwaldt, J. Hartog, R. Graaff, Roel J Huisman +7 more
2005Journal of the American Society of Nephrology389 citations
Semantic Scholar
The AGE inhibitor pyridoxamine inhibits development of retinopathy in experimental diabetes.
Alan W. Stitt, T. Gardiner, Nathan L. Anderson, P. Canning +7 more
2002Diabetes368 citations Open access
Semantic Scholar
Inhibition of NADPH Oxidase Prevents Advanced Glycation End Product–Mediated Damage in Diabetic Nephropathy Through a Protein Kinase C-α–Dependent Pathway
V. Thallas-Bonke, S. Thorpe, M. Coughlan, K. Fukami +6 more
2008Diabetes358 citations Open access
Semantic Scholar
Age-related accumulation of Maillard reaction products in human articular cartilage collagen.
N. Verzijl, J. DeGroot, Esther Oldehinkel, R. Bank +6 more
2000Biochemical Journal356 citations Open access
Semantic Scholar
Chelating Activity of Advanced Glycation End-product Inhibitors*
David L. Price, Patricia M. Rhett, S. Thorpe, J. Baynes
2001Journal of Biological Chemistry320 citations Open access
Semantic Scholar
Glycation impairs high-density lipoprotein function
C. Hedrick, S. Thorpe, M. Fu, C. M. Harper +4 more
2000Diabetologia319 citations Open access
Semantic Scholar
Advanced glycation end product interventions reduce diabetes-accelerated atherosclerosis.
J. Forbes, L. Yee, V. Thallas, M. Lassila +8 more
2004Diabetes317 citations
Semantic Scholar
Glyoxalase‐1 prevents mitochondrial protein modification and enhances lifespan in Caenorhabditis elegans
M. Morcos, Xueliang Du, Friederike Pfisterer, H. Hutter +24 more
2008Aging Cell283 citations Open access
Semantic Scholar
Pyridoxamine, an Inhibitor of Advanced Glycation Reactions, Also Inhibits Advanced Lipoxidation Reactions
J. Onorato, A. Jenkins, S. Thorpe, J. Baynes
2000Journal of Biological Chemistry258 citations Open access
Semantic Scholar
Nephrology Dialysis Transplantation Lipoxidation products as biomarkers of oxidative damage to proteins during lipid peroxidation reactions
Jesús R. Requena, M. Fu, M. Ahmed, A. J. Jenkins +2 more
2005246 citations
Semantic Scholar
Modulation of soluble receptor for advanced glycation end products by angiotensin-converting enzyme-1 inhibition in diabetic nephropathy.
J. Forbes, S. Thorpe, V. Thallas-Bonke, J. Pete +9 more
2005Journal of the American Society of Nephrology215 citations
Semantic Scholar
Simple Noninvasive Measurement of Skin Autofluorescence
R. Meerwaldt, T. Links, R. Graaff, S. Thorpe +4 more
2005Annals of the New York Academy of Sciences214 citations
Semantic Scholar
Mice deficient in both Mn superoxide dismutase and glutathione peroxidase-1 have increased oxidative damage and a greater incidence of pathology but no reduction in longevity.
Yi-Qiang Zhang, Y. Ikeno, W. Qi, A. Chaudhuri +7 more
2009The journals of gerontology. Series A, Biological sciences and medical sciences205 citations Open access
Semantic Scholar
S-(2-Succinyl)cysteine: a novel chemical modification of tissue proteins by a Krebs cycle intermediate.
N. Alderson, Yu-Ping Wang, M. Blatnik, N. Frizzell +7 more
2006Archives of Biochemistry and Biophysics199 citations
Semantic Scholar
Pyridoxamine, an inhibitor of advanced glycation and lipoxidation reactions: a novel therapy for treatment of diabetic complications.
T. Metz, N. Alderson, S. Thorpe, J. Baynes
2003Archives of Biochemistry and Biophysics190 citations
Semantic Scholar
The AGE inhibitor pyridoxamine inhibits lipemia and development of renal and vascular disease in Zucker obese rats.
N. Alderson, M. Chachich, N. Youssef, R. J. Beattie +3 more
2003Kidney International177 citations Open access
Semantic Scholar
The role of AGEs and AGE inhibitors in diabetic cardiovascular disease.
M. Thomas, J. Baynes, S. Thorpe, M. Cooper
2005Current Drug Targets170 citations
Semantic Scholar
Inactivation of Glyceraldehyde-3-Phosphate Dehydrogenase by Fumarate in Diabetes
M. Blatnik, N. Frizzell, S. Thorpe, J. Baynes
2008Diabetes142 citations Open access
Semantic Scholar
Combination therapy with the advanced glycation end product cross-link breaker, alagebrium, and angiotensin converting enzyme inhibitors in diabetes: synergy or redundancy?
M. Coughlan, V. Thallas-Bonke, J. Pete, D. M. Long +6 more
2007Endocrinology124 citations Open access
Semantic Scholar
Confocal Raman microscopy can quantify advanced glycation end product (AGE) modifications in Bruch's membrane leading to accurate, nondestructive prediction of ocular aging
J. Glenn, J. Beattie, Lindsay J. Barrett, N. Frizzell +4 more
2007The FASEB Journal118 citations
Semantic Scholar
Pyridoxamine Traps Intermediates in Lipid Peroxidation Reactions in Vivo
T. Metz, N. Alderson, M. Chachich, S. Thorpe +1 more
2003Journal of Biological Chemistry117 citations Open access
Semantic Scholar
Impaired retinal angiogenesis in diabetes: role of advanced glycation end products and galectin-3.
Alan W. Stitt, C. McGoldrick, A. Rice-McCaldin, D. McCance +5 more
2005Diabetes116 citations Open access
Semantic Scholar
Succination of Thiol Groups in Adipose Tissue Proteins in Diabetes
N. Frizzell, M. Rajesh, Matthew J. Jepson, R. Nagai +3 more
2009Journal of Biological Chemistry109 citations Open access
Semantic Scholar
Effect of antioxidants and ACE inhibition on chemical modification of proteins and progression of nephropathy in the streptozotocin diabetic rat
N. Alderson, M. Chachich, N. Frizzell, P. Canning +6 more
2004Diabetologia109 citations Open access
Semantic Scholar
Low fatty acid unsaturation: a mechanism for lowered lipoperoxidative modification of tissue proteins in mammalian species with long life spans.
R. Pamplona, M. Portero-Otín, D. Riba, J. Requena +3 more
2000The journals of gerontology. Series A, Biological sciences and medical sciences88 citations Open access
Semantic Scholar
Succination of Proteins by Fumarate
M. Blatnik, S. Thorpe, J. Baynes
2008Annals of the New York Academy of Sciences85 citations Open access
Semantic Scholar
Autoimmune response to advanced glycosylation end-products of human LDL Published, JLR Papers in Press, December 1, 2002. DOI 10.1194/jlr.M200370-JLR200
G. Virella, S. Thorpe, N. Alderson, E. Stephan +3 more
2003Journal of Lipid Research84 citations Open access
Semantic Scholar
Succination of Protein Thiols during Adipocyte Maturation
R. Nagai, Jonathan W. C. Brock, M. Blatnik, J. Baatz +5 more
2007Journal of Biological Chemistry82 citations Open access
Semantic Scholar
Role of lipids in chemical modification of proteins and development of complications in diabetes.
A. Januszewski, N. Alderson, T. Metz, S. Thorpe +1 more
2003Biochemical Society Transactions80 citations
Semantic Scholar
Proteomic analysis of the site specificity of glycation and carboxymethylation of ribonuclease.
Jonathan W. C. Brock, D. J. Hinton, W. E. Cotham, T. Metz +3 more
2003Journal of Proteome Research78 citations
Semantic Scholar
Substrates modified by advanced glycation end-products cause dysfunction and death in retinal pericytes by reducing survival signals mediated by platelet-derived growth factor
Alan W. Stitt, S. Hughes, P. Canning, O. Lynch +6 more
2004Diabetologia67 citations Open access
Semantic Scholar
Chemical modification of muscle protein in diabetes.
N. Alt, J. Carson, N. Alderson, Yu-Ping Wang +4 more
2004Archives of Biochemistry and Biophysics62 citations
Semantic Scholar
Advanced glycation end-products and methionine sulphoxide in skin collagen of patients with type 1 diabetes
Y. Yu, S. Thorpe, A. Jenkins, J. Shaw +9 more
2006Diabetologia56 citations Open access
Semantic Scholar
Lipid peroxidation and protein modification in a mouse model of chronic iron overload.
M. Sochaski, W. Bartfay, S. Thorpe, J. Baynes +3 more
2002Metabolism: Clinical and Experimental56 citations
Semantic Scholar
SUCCINATION* OF PROTEIN THIOLS DURING ADIPOCYTE MATURATION – A BIOMARKER OF MITOCHONDRIAL STRESS
R. Nagai, Jonathan W. C. Brock, M. Blatnik, J. Baatz +5 more
200753 citations
Semantic Scholar
Proteomic Analysis of Arginine Adducts on Glyoxal-modified Ribonuclease*
W. E. Cotham, T. Metz, P. L. Ferguson, Jonathan W. C. Brock +4 more
2004Molecular & Cellular Proteomics52 citations Open access
Semantic Scholar
CML: a brief history
S. Thorpe, J. Baynes
200250 citations
Semantic Scholar
Renal Effects of Oral Maillard Reaction Product Load in the Form of Bread Crusts in Healthy and Subtotally Nephrectomized Rats
K. Šebeková, T. Hofmann, P. Boor, O. Uličná +5 more
2005Annals of the New York Academy of Sciences49 citations
Semantic Scholar
Advanced glycation end products and the absence of premature atherosclerosis in glycogen storage disease Ia
N. den Hollander, D. Mulder, R. Graaff, S. Thorpe +3 more
2007Journal of Inherited Metabolic Disease48 citations Open access
Semantic Scholar
Increased methionine sulfoxide content of apoA-I in type 1 diabetes Published, JLR Papers in Press, January 17, 2008.
Jonathan W. C. Brock, A. Jenkins, T. Lyons, R. Klein +5 more
2008Journal of Lipid Research46 citations Open access
Semantic Scholar
Tissue‐Specific Variation in Glycation of Proteins in Diabetes: Evidence for a Functional Role of Amadoriase Enzymes
Sarah M. Brown, Della M. Smith, N. Alt, S. Thorpe +1 more
2005Annals of the New York Academy of Sciences46 citations
Semantic Scholar
Dietary Bread Crust Advanced Glycation End Products Bind to the Receptor for AGEs in HEK‐293 Kidney Cells but Are Rapidly Excreted after Oral Administration to Healthy and Subtotally Nephrectomized Rats
V. Somoza, M. Lindenmeier, T. Hofmann, O. Frank +11 more
2005Annals of the New York Academy of Sciences46 citations
Semantic Scholar
Advanced glycation and advanced lipoxidation: possible role in initiation and progression of diabetic retinopathy.
Alan W. Stitt, N. Frizzell, S. Thorpe
2004Current pharmaceutical design45 citations
Semantic Scholar

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T. Metz — researcher profile on SciRah

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M. Chachich — researcher profile on SciRah