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R. Kopperud · SciRah

Researcher profile · Semantic Scholar

R. Kopperud

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R. Kopperud — researcher profile on SciRah

h-index: 23
Works: 46
Citations: 2,242

Most-cited papers

Identification of twelve new susceptibility loci for different histotypes of epithelial ovarian cancer
C. Phelan, Karoline B. Kuchenbaecker, J. Tyrer, S. Kar +410 more
2017Nature Genetics399 citations Open access
Semantic Scholar
cAMP effector mechanisms. Novel twists for an ‘old’ signaling system
R. Kopperud, C. Krakstad, F. Selheim, S. Døskeland
2003FEBS Letters207 citations Open access
Semantic Scholar
Genome-wide Meta-analyses of Breast, Ovarian and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by At Least Two Cancer Types
S. Kar, J. Beesley, A. A. Al Olama, K. Michailidou +223 more
2016Cancer Discovery188 citations Open access
Semantic Scholar
Epac1 and cAMP-dependent Protein Kinase Holoenzyme Have Similar cAMP Affinity, but Their cAMP Domains Have Distinct Structural Features and Cyclic Nucleotide Recognition*
Khanh K. Dao, K. Teigen, R. Kopperud, E. Hodneland +4 more
2006Journal of Biological Chemistry157 citations Open access
Semantic Scholar
Association of vitamin D levels and risk of ovarian cancer: a Mendelian randomization study.
Jue-Sheng Ong, G. Cuéllar-Partida, Yi Lu, P. Fasching +107 more
2016International Journal of Epidemiology114 citations Open access
Semantic Scholar
L1CAM expression in endometrial carcinomas: an ENITEC collaboration study
L. V. D. van der Putten, N. Visser, K. K. van de Vijver, M. Santacana +24 more
2016British Journal of Cancer104 citations Open access
Semantic Scholar
Shared genetics underlying epidemiological association between endometriosis and ovarian cancer.
Yi Lu, G. Cuéllar-Partida, J. Painter, D. Nyholt +107 more
2015Human Molecular Genetics78 citations Open access
Semantic Scholar
Adult body mass index and risk of ovarian cancer by subtype: a Mendelian randomization study.
S. Dixon, C. Nagle, A. Thrift, P. Pharoah +109 more
2016International Journal of Epidemiology76 citations Open access
Semantic Scholar
Search for new cyclic AMP‐binding proteins
S. Dremier, R. Kopperud, S. Døskeland, J. E. Dumont +1 more
2003FEBS Letters72 citations
Semantic Scholar
Formation of Inactive cAMP-saturated Holoenzyme of cAMP-dependent Protein Kinase under Physiological Conditions*
R. Kopperud, A. Christensen, Endre Kjærland, K. Viste +2 more
2002Journal of Biological Chemistry70 citations Open access
Semantic Scholar
Androgen receptor as potential therapeutic target in metastatic endometrial cancer
I. L. Tangen, T. B. Onyango, R. Kopperud, A. Berg +7 more
2016OncoTarget66 citations Open access
Semantic Scholar
Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer
C. Phelan, K. Kuchenbaecker, J. Tyrer, S. Kar +410 more
2017Nature Genetics62 citations Open access
Semantic Scholar
Nuclear export of the human immunodeficiency virus type 1 nucleocytoplasmic shuttle protein Rev is mediated by its activation domain and is blocked by transdominant negative mutants
A. Szilvay, K. Brokstad, R. Kopperud, Gunnar Haukenes +1 more
1995Journal of Virology59 citations Open access
Semantic Scholar
Added Value of Estrogen Receptor, Progesterone Receptor, and L1 Cell Adhesion Molecule Expression to Histology-Based Endometrial Carcinoma Recurrence Prediction Models: An ENITEC Collaboration Study
L. V. D. van der Putten, N. Visser, K. K. van de Vijver, M. Santacana +25 more
2018International Journal of Gynecologic Cancer58 citations
Semantic Scholar
Substrate Enhances the Sensitivity of Type I Protein Kinase A to cAMP*
K. Viste, R. Kopperud, A. Christensen, S. Døskeland
2005Journal of Biological Chemistry48 citations Open access
Semantic Scholar
8-Substituted cAMP analogues reveal marked differences in adaptability, hydrogen bonding, and charge accommodation between homologous binding sites (AI/AII and BI/BII) in cAMP kinase I and II.
F. Schwede, A. Christensen, Susanne Liauw, Thomas Hippe +3 more
2000Biochemistry46 citations
Semantic Scholar
Activation of Protein Kinase A and Exchange Protein Directly Activated by cAMP Promotes Adipocyte Differentiation of Human Mesenchymal Stem Cells
Bing-Bing Jia, L. Madsen, R. Petersen, N. Techer +7 more
2012PLoS ONE45 citations Open access
Semantic Scholar
White Blood Cell BRCA1 Promoter Methylation Status and Ovarian Cancer Risk
P. Lønning, E. Berge, M. Bjørnslett, Laura Minsaas +20 more
2018Annals of Internal Medicine41 citations
Semantic Scholar
Expression of L1CAM in curettage or high L1CAM level in preoperative blood samples predicts lymph node metastases and poor outcome in endometrial cancer patients
I. L. Tangen, R. Kopperud, N. Visser, A. Staff +9 more
2017British Journal of Cancer41 citations Open access
Semantic Scholar
Increased microvascular permeability in mice lacking Epac1 (Rapgef3)
R. Kopperud, C. B. Rygh, T. V. Karlsen, C. Krakstad +13 more
2016Acta Physiologica40 citations Open access
Semantic Scholar
Multimodal Imaging of Orthotopic Mouse Model of Endometrial Carcinoma
I. Haldorsen, M. Popa, Tina Fonnes, N. Brekke +7 more
2015PLoS ONE38 citations Open access
Semantic Scholar
Assessing the genetic architecture of epithelial ovarian cancer histological subtypes
G. Cuéllar-Partida, Yi Lu, S. Dixon, P. Fasching +104 more
2016Human Genetics28 citations Open access
Semantic Scholar
Multi-parametric single cell evaluation defines distinct drug responses in healthy hematologic cells that are retained in corresponding malignant cell types
M. Majumder, Aino-Maija Leppä, M. Hellesøy, P. Dowling +13 more
2019Haematologica24 citations Open access
Semantic Scholar
The cAMP-dependent protein kinase pathway as therapeutic target: possibilities and pitfalls.
R. Kleppe, C. Krakstad, F. Selheim, R. Kopperud +1 more
2011Current Topics in Medicinal Chemistry21 citations
Semantic Scholar
Cross-Cancer Genome-Wide Association Study of Endometrial Cancer and Epithelial Ovarian Cancer Identifies Genetic Risk Regions Associated with Risk of Both Cancers
Dylan M Glubb, D. Thompson, K. Aben, Ahmad Alsulimani +149 more
2020Cancer Epidemiology, Biomarkers and Prevention20 citations Open access
Semantic Scholar
Long-term consumption of an obesogenic high fat diet prior to ischemia-reperfusion mediates cardioprotection via Epac1-dependent signaling
Fridtjov Edland, A. Wergeland, R. Kopperud, Kathrine Sivertsen Åsrud +8 more
2016Nutrition and Metabolism20 citations Open access
Semantic Scholar
Off-target effect of the Epac agonist 8-pCPT-2'-O-Me-cAMP on P2Y12 receptors in blood platelets.
L. Herfindal, Gyrid Nygaard, R. Kopperud, C. Krakstad +2 more
2013Biochemical and Biophysical Research Communications - BBRC19 citations
Semantic Scholar
Epac1-deficient mice have bleeding phenotype and thrombocytes with decreased GPIbβ expression
Gyrid Nygaard, L. Herfindal, K. S. Åsrud, Ronja Bjørnstad +9 more
2017Scientific Reports18 citations Open access
Semantic Scholar
Adult height is associated with increased risk of ovarian cancer: a Mendelian randomisation study
S. Dixon-Suen, C. Nagle, A. Thrift, P. Pharoah +116 more
2018British Journal of Cancer15 citations Open access
Semantic Scholar
Deletion of exchange proteins directly activated by cAMP (Epac) causes defects in hippocampal signaling in female mice
Reidun Aesoy, H. Muwonge, K. S. Åsrud, Misbah Sabir +6 more
2018PLoS ONE12 citations Open access
Semantic Scholar
Dipyridamole synergizes with nitric oxide to prolong inhibition of thrombin-induced platelet shape change
B. O. Jensen, R. Kleppe, R. Kopperud, Gyrid Nygaard +3 more
2011Platelets10 citations
Semantic Scholar
Epac1 null mice have nephrogenic diabetes insipidus with deficient corticopapillary osmotic gradient and weaker collecting duct tight junctions
Kathrine Sivertsen Åsrud, Ronja Bjørnstad, R. Kopperud, Line Pedersen +8 more
2020Acta Physiologica9 citations Open access
Semantic Scholar
Introduction of Aromatic Ring-Containing Substituents in Cyclic Nucleotides Is Associated with Inhibition of Toxin Uptake by the Hepatocyte Transporters OATP 1B1 and 1B3
L. Herfindal, C. Krakstad, L. Myhren, H. Hagland +5 more
2014PLoS ONE9 citations Open access
Semantic Scholar
Liquid Biopsies in Solid Cancers: Implementation in a Nordic Healthcare System
O. Nordgård, Rakel Brendsdal Forthun, Morten Lapin, B. Grønberg +7 more
2021Cancers8 citations Open access
Semantic Scholar
Modulation of phospho-proteins by interferon-alpha and valproic acid in acute myeloid leukemia
R. Forthun, M. Hellesøy, A. Sulen, R. Kopperud +4 more
2019Journal of Cancer Research and Clinical Oncology8 citations Open access
Semantic Scholar
Time-dependent inhibitory effects of cGMP-analogues on thrombin-induced platelet-derived microparticles formation, platelet aggregation, and P-selectin expression.
Gyrid Nygaard, L. Herfindal, R. Kopperud, A. Aragay +4 more
2014Biochemical and Biophysical Research Communications - BBRC6 citations Open access
Semantic Scholar
POSTMan (POST‐translational modification analysis), a software application for PTM discovery
M. Arntzen, Christoffer Leif Osland, Christopher Rasch-Olsen Raa, R. Kopperud +3 more
2009Proteomics5 citations
Semantic Scholar
Microvascular permeability in the absence of Epac1 activity
T. V. Karlsen, R. Kopperud, Å. Lidén, Cecilie Brekke Rygh +2 more
20122 citations Open access
Semantic Scholar
Epac1 Functions as a Central Cardioprotective cAMP Effector During Ischemic and β-adrenergic Preconditioning.
M. Eriksen, F. E. Ravn, A. Aspevik, J. T. Haugom +6 more
2026Cardiovascular Drugs and Therapy0 citations Open access
Semantic Scholar
CT-954: Intradermal Vididencel Vaccination in Measurable Residual Disease-Positive Acute Myeloid Leukemia Patients Results in Increased Antigen-Presenting Cells and T Cells at the Injection Site and Local Immune-Cell Interactions
Øystein Sefland, R. Kopperud, H. V. van Zeeburg, J. Rovers +3 more
2025Clinical Lymphoma, Myeloma & Leukemia0 citations Open access
Semantic Scholar
POSTER: CT-954 Intradermal Vididencel Vaccination in Measurable Residual Disease-Positive Acute Myeloid Leukemia Patients Results in Increased Antigen-Presenting Cells and T Cells at the Injection Site and Local Immune-Cell Interactions
Øystein Sefland, R. Kopperud, H. V. van Zeeburg, J. Rovers +3 more
2025Clinical Lymphoma, Myeloma & Leukemia0 citations
Semantic Scholar
Intradermal Vaccination with Vididencel in MRD+ AML-Patients Leads to Increase in Antigen Presenting Cells and T-Cells to the Injection Site, Visualized Using Imaging Mass Cytometry, Showing Local Immune Cell Interactions Leading to Systemic Immune Responses
Oystein Sefland, R. Kopperud, H. V. van Zeeburg, J. Rovers +3 more
2023Blood0 citations Open access
Semantic Scholar
KMT2D mutations and TP53 disruptions are poor prognostic biomarkers in mantle cell lymphoma receiving high-dose therapy a FIL study
M. Majumder, Aino-Maija Leppä, M. Hellesøy, P. Dowling +15 more
20200 citations
Semantic Scholar
Epac1-deficient mice have bleeding phenotype and thrombocytes with decreased GPIbβ expression
Gyrid Nygaard, L. Herfindal, K. S. Åsrud, Ronja Bjørnstad +9 more
2017Scientific Reports0 citations Open access
Semantic Scholar
randomization Association of vitamin D levels and risk of ovarian cancer: a Mendelian randomization study
Jue-Sheng Ong, G. Cuéllar-Partida, Yi Lu, P. Fasching +90 more
20160 citations
Semantic Scholar
Mendelian randomization Association of vitamin D levels and risk of ovarian cancer : a Mendelian randomization study
Jue-Sheng Ong, G. Cuéllar-Partida, Yi Lu, P. Fasching +90 more
20160 citations
Semantic Scholar

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