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P. Dowling · SciRah

Researcher profile · Semantic Scholar

P. Dowling

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P. Dowling — researcher profile on SciRah

h-index: 39
Works: 156
Citations: 4,172

Most-cited papers

Bone Disease in Multiple Myeloma: Pathophysiology and Management
Abdul Hameed, J. Brady, P. Dowling, M. Clynes +1 more
2014Cancer Growth and Metastasis186 citations Open access
Semantic Scholar
Targeting Proteotoxic Stress in Cancer: A Review of the Role that Protein Quality Control Pathways Play in Oncogenesis
Matthew Ho Zhi Guang, Emma L. Kavanagh, L. Dunne, P. Dowling +9 more
2019Cancers109 citations Open access
Semantic Scholar
The development of cisplatin resistance in neuroblastoma is accompanied by epithelial to mesenchymal transition in vitro.
O. Piskareva, H. Harvey, J. Nolan, R. Conlon +7 more
2015Cancer Letters96 citations Open access
Semantic Scholar
Circulating miRNAs miR-34a and miR-150 associated with colorectal cancer progression
Sinéad T. Aherne, S. Madden, D. Hughes, B. Pardini +6 more
2015BMC Cancer91 citations Open access
Semantic Scholar
Fiber-Type Shifting in Sarcopenia of Old Age: Proteomic Profiling of the Contractile Apparatus of Skeletal Muscles
P. Dowling, S. Gargan, D. Swandulla, K. Ohlendieck
2023International Journal of Molecular Sciences89 citations Open access
Semantic Scholar
Mitochondrial Dysfunction Reveals the Role of mRNA Poly(A) Tail Regulation in Oculopharyngeal Muscular Dystrophy Pathogenesis
A. Chartier, P. Klein, Stéphanie Pierson, N. Barbezier +15 more
2015PLoS Genetics68 citations Open access
Semantic Scholar
Current Methods of Post-Translational Modification Analysis and Their Applications in Blood Cancers
Katie Dunphy, P. Dowling, D. Bazou, P. O'Gorman
2021Cancers57 citations Open access
Semantic Scholar
Label‐free mass spectrometric analysis of the mdx‐4cv diaphragm identifies the matricellular protein periostin as a potential factor involved in dystrophinopathy‐related fibrosis
A. Holland, P. Dowling, P. Meleady, M. Henry +4 more
2015Proteomics57 citations
Semantic Scholar
Aminopeptidase Expression in Multiple Myeloma Associates with Disease Progression and Sensitivity to Melflufen
Juho J Miettinen, R. Kumari, G. A. Traustadottir, Maiju-Emilia Huppunen +14 more
2021Cancers51 citations Open access
Semantic Scholar
Proteomic analysis of dystrophin deficiency and associated changes in the aged mdx-4cv heart model of dystrophinopathy-related cardiomyopathy.
Sandra Murphy, P. Dowling, Margit Zweyer, R. R. Mundegar +4 more
2016Journal of Proteomics47 citations
Semantic Scholar
PP2A inhibition overcomes acquired resistance to HER2 targeted therapy
M. McDermott, B. Browne, N. Conlon, N. O'Brien +7 more
2014Molecular Cancer46 citations Open access
Semantic Scholar
Pathoproteomic profiling of the skeletal muscle matrisome in dystrophinopathy associated myofibrosis
A. Holland, Sandra Murphy, P. Dowling, K. Ohlendieck
2016Proteomics43 citations Open access
Semantic Scholar
The Dystrophin Node as Integrator of Cytoskeletal Organization, Lateral Force Transmission, Fiber Stability and Cellular Signaling in Skeletal Muscle
P. Dowling, S. Gargan, Sandra Murphy, Margit Zweyer +3 more
2021Proteomes42 citations Open access
Semantic Scholar
Multiple myeloma gammopathies Targeting histone deacetylase 3 ( HDAC 3 ) in the bone marrow microenvironment inhibits multiple myeloma proliferation by modulating exosomes and IL-6 trans-signaling
M. Ho, Tian-Zeng Chen, Jiye Liu, P. Dowling +18 more
201941 citations
Semantic Scholar
OVERCOMING MULTIPLE MYELOMA DRUG RESISTANCE IN THE ERA OF CANCER “OMICS”
Matthew Ho Zhi Guang, A. McCann, G. Bianchi, Li Zhang +4 more
2017Leukemia and Lymphoma40 citations Open access
Semantic Scholar
Comparative Skeletal Muscle Proteomics Using Two-Dimensional Gel Electrophoresis
Sandra Murphy, P. Dowling, K. Ohlendieck
2016Proteomes40 citations Open access
Semantic Scholar
Proteomic profiling of mdx-4cv serum reveals highly elevated levels of the inflammation-induced plasma marker haptoglobin in muscular dystrophy
Sandra Murphy, P. Dowling, Margit Zweyer, M. Henry +4 more
2017International Journal of Molecular Medicine39 citations Open access
Semantic Scholar
Proteomic analysis of bronchoalveolar lavage fluid (BALF) from lung cancer patients using label-free mass spectrometry
A. Hmmier, M. E. O'Brien, V. Lynch, M. Clynes +2 more
2017BBA Clinical36 citations Open access
Semantic Scholar
Proteomic profiling of carbonic anhydrase CA3 in skeletal muscle
P. Dowling, S. Gargan, Margit Zweyer, H. Sabir +2 more
2021Espert Review of Proteomics31 citations
Semantic Scholar
Proteomic profiling of muscle fibre type shifting in neuromuscular diseases
P. Dowling, Sandra Murphy, K. Ohlendieck
2016Espert Review of Proteomics31 citations
Semantic Scholar
Abnormal levels of heterogeneous nuclear ribonucleoprotein A2B1 (hnRNPA2B1) in tumour tissue and blood samples from patients diagnosed with lung cancer.
P. Dowling, D. Pollard, A. Larkin, M. Henry +11 more
2015Molecular Biosystems31 citations
Semantic Scholar
Elevated levels of 14-3-3 proteins, serotonin, gamma enolase and pyruvate kinase identified in clinical samples from patients diagnosed with colorectal cancer.
P. Dowling, D. Hughes, A. Larkin, J. Meiller +9 more
2015Clinica chimica acta; international journal of clinical chemistry31 citations
Semantic Scholar
Emerging proteomic biomarkers of X-linked muscular dystrophy
P. Dowling, Sandra Murphy, Margit Zweyer, Maren Raucamp +2 more
2019Expert Review of Molecular Diagnostics29 citations Open access
Semantic Scholar
Mass Spectrometry-Based Identification of Muscle-Associated and Muscle-Derived Proteomic Biomarkers of Dystrophinopathies
P. Dowling, A. Holland, K. Ohlendieck
2014Journal of Neuromuscular Diseases29 citations Open access
Semantic Scholar
Targeting Histone Deacetylase 3 (HDAC3) in the Bone Marrow Microenvironment Inhibits Multiple Myeloma Proliferation by Modulating Exosomes and IL-6 Trans-Signaling
M. Ho, Tian-Zeng Chen, Jiye Liu, P. Dowling +17 more
2019Leukemia25 citations Open access
Semantic Scholar
A novel inhibitory anti-invasive MAb isolated using phenotypic screening highlights AnxA6 as a functionally relevant target protein in pancreatic cancer
D. O'Sullivan, P. Dowling, H. Joyce, E. Mcauley +11 more
2017British Journal of Cancer25 citations Open access
Semantic Scholar
Proteome-wide Changes in the mdx-4cv Spleen due to Pathophysiological Cross Talk with Dystrophin-Deficient Skeletal Muscle
P. Dowling, S. Gargan, Margit Zweyer, M. Henry +3 more
2020iScience24 citations Open access
Semantic Scholar
Multi-parametric single cell evaluation defines distinct drug responses in healthy hematologic cells that are retained in corresponding malignant cell types
M. Majumder, Aino-Maija Leppä, M. Hellesøy, P. Dowling +13 more
2019Haematologica24 citations Open access
Semantic Scholar
Pathoproteomics of testicular tissue deficient in the GARP component VPS54: The wobbler mouse model of globozoospermia
H. Jockusch, A. Holland, Lisa Staunton, T. Schmitt-John +3 more
2014Proteomics23 citations Open access
Semantic Scholar
Dynamics of CXCR4 positive circulating tumor cells in prostate cancer patients during radiotherapy
D. Klusa, F. Lohaus, A. Franken, Marian Baumbach +19 more
2023International Journal of Cancer22 citations Open access
Semantic Scholar
Characterization of Contractile Proteins from Skeletal Muscle Using Gel-Based Top-Down Proteomics
P. Dowling, Margit Zweyer, D. Swandulla, K. Ohlendieck
2019Proteomes22 citations Open access
Semantic Scholar
Elevated 12‐hydroxyeicosatetraenoic acid (12‐HETE) levels in serum of individuals with newly diagnosed Type 1 diabetes
E. Hennessy, A. Rakovac Tisdall, N. Murphy, A. Carroll +6 more
2017Diabetic Medicine22 citations
Semantic Scholar
Transferrin-bound proteins as potential biomarkers for advanced breast cancer patients
P. Dowling, V. Palmerini, M. Henry, P. Meleady +6 more
2014BBA Clinical22 citations Open access
Semantic Scholar
Protocol for the Bottom-Up Proteomic Analysis of Mouse Spleen
P. Dowling, S. Gargan, Margit Zweyer, M. Henry +3 more
2020STAR Protocols21 citations Open access
Semantic Scholar
Proteomic profiling of impaired excitation–contraction coupling and abnormal calcium handling in muscular dystrophy
P. Dowling, S. Gargan, D. Swandulla, K. Ohlendieck
2022Proteomics20 citations Open access
Semantic Scholar
Proteomic and cell biological profiling of the renal phenotype of the mdx-4cv mouse model of Duchenne muscular dystrophy.
P. Dowling, Margit Zweyer, Maren Raucamp, M. Henry +3 more
2019European Journal of Cell Biology20 citations Open access
Semantic Scholar
Novel panel of protein biomarkers to predict response to bortezomib-containing induction regimens in multiple myeloma patients
K. Ting, M. Henry, J. Meiller, A. Larkin +5 more
2017BBA Clinical20 citations Open access
Semantic Scholar
Metabolomic and proteomic analysis of breast cancer patient samples suggests that glutamate and 12-HETE in combination with CA15-3 may be useful biomarkers reflecting tumour burden
P. Dowling, M. Henry, P. Meleady, Colin Clarke +9 more
2015Metabolomics19 citations
Semantic Scholar
Proteomic profiling of fatty acid binding proteins in muscular dystrophy
P. Dowling, S. Gargan, Margit Zweyer, D. Swandulla +1 more
2020Espert Review of Proteomics18 citations
Semantic Scholar
Proteomic profiling of giant skeletal muscle proteins
Sandra Murphy, P. Dowling, Margit Zweyer, D. Swandulla +1 more
2019Espert Review of Proteomics18 citations Open access
Semantic Scholar
Clinical utility of C‐terminal telopeptide of type 1 collagen in multiple myeloma
K. Ting, J. Brady, Abdul Hameed, Giao N. Lê +10 more
2016British Journal of Haematology18 citations
Semantic Scholar
Clinical Proteomics of Biofluids in Haematological Malignancies
Katie Dunphy, Kelly O'Mahoney, P. Dowling, P. O'Gorman +1 more
2021International Journal of Molecular Sciences16 citations Open access
Semantic Scholar
Proteomic profiling of the interface between the stomach wall and the pancreas in dystrophinopathy
P. Dowling, S. Gargan, Margit Zweyer, H. Sabir +4 more
2021European Journal of Translational Myology15 citations Open access
Semantic Scholar
Proteomic Identification of Markers of Membrane Repair, Regeneration and Fibrosis in the Aged and Dystrophic Diaphragm
S. Gargan, P. Dowling, Margit Zweyer, M. Henry +3 more
2022Life14 citations Open access
Semantic Scholar
Identification of marker proteins of muscular dystrophy in the urine proteome from the mdx-4cv model of dystrophinopathy.
S. Gargan, P. Dowling, Margit Zweyer, D. Swandulla +1 more
2020Molecular Omics14 citations Open access
Semantic Scholar
Development and characterisation of a panel of phosphatidylinositide 3-kinase – mammalian target of rapamycin inhibitor resistant lung cancer cell lines
S. Heavey, P. Dowling, Gillian Moore, M. Barr +6 more
2018Scientific Reports14 citations Open access
Semantic Scholar
7B7: a novel antibody directed against the Ku70/Ku80 heterodimer blocks invasion in pancreatic and lung cancer cells
D. O'Sullivan, M. Henry, H. Joyce, N. Walsh +7 more
2014Tumor Biology14 citations Open access
Semantic Scholar
Proteomic Identification of Saliva Proteins as Noninvasive Diagnostic Biomarkers.
E. O'Sullivan, P. Dowling, D. Swandulla, K. Ohlendieck
2023Methods in molecular biology13 citations
Semantic Scholar
Mass Spectrometric Profiling of Extraocular Muscle and Proteomic Adaptations in the mdx-4cv Model of Duchenne Muscular Dystrophy
S. Gargan, P. Dowling, Margit Zweyer, J. Reimann +4 more
2021Life13 citations Open access
Semantic Scholar
Next generation proteomics with drug sensitivity screening identifies sub-clones informing therapeutic and drug development strategies for multiple myeloma patients
Ciara Tierney, D. Bazou, M. Majumder, P. Anttila +4 more
2021Scientific Reports13 citations Open access
Semantic Scholar

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