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C. Bouzat · SciRah

Researcher profile · Semantic Scholar

C. Bouzat

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C. Bouzat — researcher profile on SciRah

h-index: 36
Works: 117
Citations: 3,775

Most-cited papers

Coupling of agonist binding to channel gating in an ACh-binding protein linked to an ion channel
C. Bouzat, Fernanda Gumilar, G. Spitzmaul, Hai-Long Wang +4 more
2004Nature274 citations Open access
Semantic Scholar
Understanding the Bases of Function and Modulation of α7 Nicotinic Receptors: Implications for Drug Discovery
J. Corradi, C. Bouzat
2016Molecular Pharmacology163 citations
Semantic Scholar
Molecular mechanisms and binding site locations for noncompetitive antagonists of nicotinic acetylcholine receptors.
H. Arias, Pankaj Bhumireddy, C. Bouzat
2006International Journal of Biochemistry and Cell Biology138 citations
Semantic Scholar
The Interface between Extracellular and Transmembrane Domains of Homomeric Cys-Loop Receptors Governs Open-Channel Lifetime and Rate of Desensitization
C. Bouzat, M. Bartos, J. Corradi, S. Sine
2008Journal of Neuroscience126 citations Open access
Semantic Scholar
Number and Locations of Agonist Binding Sites Required to Activate Homomeric Cys-Loop Receptors
D. Rayes, M. J. De Rosa, S. Sine, C. Bouzat
2009Journal of Neuroscience117 citations Open access
Semantic Scholar
An intrinsic GABAergic system in human lymphocytes.
L. Dionisio, M. D. De Rosa, C. Bouzat, María del Carmen Esandi
2011Neuropharmacology111 citations Open access
Semantic Scholar
Stoichiometry for activation of neuronal α7 nicotinic receptors
N. Andersen, J. Corradi, S. Sine, C. Bouzat
2013Proceedings of the National Academy of Sciences of the United States of America88 citations Open access
Semantic Scholar
Stoichiometry of the α9α10 Nicotinic Cholinergic Receptor
P. Plazas, E. Katz, M. E. Gómez-Casati, C. Bouzat +1 more
2005Journal of Neuroscience88 citations Open access
Semantic Scholar
Molecular function of α7 nicotinic receptors as drug targets
C. Bouzat, Matías Lasala, B. E. Nielsen, J. Corradi +1 more
2017Journal of Physiology85 citations Open access
Semantic Scholar
Nicotinic Receptor Fourth Transmembrane Domain
C. Bouzat, F. Barrantes, S. Sine
2000The Journal of General Physiology77 citations Open access
Semantic Scholar
Single-channel and structural foundations of neuronal α7 acetylcholine receptor potentiation
Corrie J. B. daCosta, C. Free, J. Corradi, C. Bouzat +1 more
2011Journal of Neuroscience71 citations Open access
Semantic Scholar
Single-channel kinetic analysis for activation and desensitization of homomeric 5-HT(3)A receptors.
J. Corradi, Fernanda Gumilar, C. Bouzat
2009Biophysical Journal70 citations Open access
Semantic Scholar
Exploring the positive allosteric modulation of human α7 nicotinic receptors from a single-channel perspective.
N. Andersen, B. E. Nielsen, J. Corradi, M. F. Tolosa +3 more
2016Neuropharmacology66 citations Open access
Semantic Scholar
Alpha 7 nicotinic acetylcholine receptor modulates lymphocyte activation.
M. D. De Rosa, L. Dionisio, E. Agriello, C. Bouzat +1 more
2009Life Science63 citations Open access
Semantic Scholar
Molecular mechanisms of inhibition of nicotinic acetylcholine receptors by tricyclic antidepressants.
Fernanda Gumilar, H. Arias, G. Spitzmaul, C. Bouzat
2003Neuropharmacology63 citations Open access
Semantic Scholar
An ER‐resident membrane protein complex regulates nicotinic acetylcholine receptor subunit composition at the synapse
Ruta B. Almedom, Jana F. Liewald, Guillermina Hernando, C. Schultheis +6 more
2009EMBO Journal55 citations Open access
Semantic Scholar
Molecular Modulation of Human α7 Nicotinic Receptor by Amyloid-β Peptides
Matías Lasala, C. Fabiani, J. Corradi, S. Antollini +1 more
2019Frontiers in Cellular Neuroscience54 citations Open access
Semantic Scholar
Subunit-selective contribution to channel gating of the M4 domain of the nicotinic receptor.
C. Bouzat, Fernanda Gumilar, María del Carmen Esandi, S. Sine
2002Biophysical Journal51 citations Open access
Semantic Scholar
Nicotinic acetylcholine receptors at the single‐channel level
C. Bouzat, S. Sine
2018British Journal of Pharmacology50 citations Open access
Semantic Scholar
Structural Basis of Activation of Cys-Loop Receptors: the Extracellular–Transmembrane Interface as a Coupling Region
M. Bartos, J. Corradi, C. Bouzat
2009Molecular Neurobiology49 citations Open access
Semantic Scholar
Molecular Basis of the Differential Sensitivity of Nematode and Mammalian Muscle to the Anthelmintic Agent Levamisole*
D. Rayes, M. J. De Rosa, M. Bartos, C. Bouzat
2004Journal of Biological Chemistry49 citations Open access
Semantic Scholar
Expression and Functional Role of α7 Nicotinic Receptor in Human Cytokine-stimulated Natural Killer (NK) Cells*
S. Zanetti, A. Ziblat, Nicolás I Torres, N. Zwirner +1 more
2016Journal of Biological Chemistry47 citations Open access
Semantic Scholar
New insights into the structural bases of activation of Cys-loop receptors.
C. Bouzat
2012Journal of Physiology - Paris47 citations Open access
Semantic Scholar
Relationship between alpha 7 nAChR and apoptosis in human lymphocytes.
M. J. De Rosa, María del Carmen Esandi, Andrés Garelli, D. Rayes +1 more
2005Journal of Neuroimmunology47 citations
Semantic Scholar
Contribution of Subunits to Caenorhabditis elegans Levamisole-Sensitive Nicotinic Receptor Function
Guillermina Hernando, I. Bergé, D. Rayes, C. Bouzat
2012Molecular Pharmacology46 citations Open access
Semantic Scholar
Interaction of Bupropion with Muscle-Type Nicotinic Acetylcholine Receptors in Different Conformational States
H. Arias, Fernanda Gumilar, A. Rosenberg, Katarzyna M Targowska-Duda +5 more
2009Biochemistry44 citations Open access
Semantic Scholar
Relationship between a 7 nAChR and apoptosis in human lymphocytes
J. De Rosa, del Carmen Esandi, Andrés Garelli, D. Rayes +1 more
201843 citations
Semantic Scholar
Caenorhabditis elegans Neuromuscular Junction: GABA Receptors and Ivermectin Action
Guillermina Hernando, C. Bouzat
2014PLoS ONE39 citations Open access
Semantic Scholar
Single-Channel Kinetic Analysis of Chimeric α7–5HT3A Receptors
D. Rayes, G. Spitzmaul, S. Sine, C. Bouzat
2005Molecular Pharmacology39 citations
Semantic Scholar
Activation of Single Nicotinic Receptor Channels from Caenorhabditis elegans Muscle
D. Rayes, M. Flamini, Guillermina Hernando, C. Bouzat
2007Molecular Pharmacology37 citations Open access
Semantic Scholar
Alterations in the memory of rat offspring exposed to low levels of fluoride during gestation and lactation: Involvement of the α7 nicotinic receptor and oxidative stress.
M. Bartos, Fernanda Gumilar, C. Gallegos, Cristina Bras +6 more
2018Reproductive Toxicology36 citations Open access
Semantic Scholar
Functional Relationships Between Agonist Binding Sites and Coupling Regions of Homomeric Cys-loop Receptors
N. Andersen, J. Corradi, M. Bartos, S. Sine +1 more
2011Journal of Neuroscience36 citations Open access
Semantic Scholar
The local anaesthetics proadifen and adiphenine inhibit nicotinic receptors by different molecular mechanisms
G. Spitzmaul, Fernanda Gumilar, J. Dilger, C. Bouzat
2009British Journal of Pharmacology35 citations Open access
Semantic Scholar
Molecular mechanisms and binding site location for the noncompetitive antagonist crystal violet on nicotinic acetylcholine receptors.
H. Arias, Pankaj Bhumireddy, G. Spitzmaul, J. Trudell +1 more
2006Biochemistry34 citations
Semantic Scholar
Caenorhabditis elegans muscle Cys-loop receptors as novel targets of terpenoids with potential anthelmintic activity
Guillermina Hernando, Ornella Turani, C. Bouzat
2019PLoS Neglected Tropical Diseases32 citations Open access
Semantic Scholar
A human-specific, truncated α7 nicotinic receptor subunit assembles with full-length α7 and forms functional receptors with different stoichiometries
Matías Lasala, J. Corradi, A. Bruzzone, María del Carmen Esandi +1 more
2018Journal of Biological Chemistry29 citations Open access
Semantic Scholar
Molecular function of the novel α7β2 nicotinic receptor
B. E. Nielsen, Teresa Minguez, I. Bermúdez, C. Bouzat
2018Cellular and Molecular Life Sciences29 citations Open access
Semantic Scholar
Differential Contribution of Subunit Interfaces to α9α10 Nicotinic Acetylcholine Receptor Function
J. Boffi, Irina Marcovich, JasKiran K. Gill-Thind, J. Corradi +8 more
2017Molecular Pharmacology29 citations Open access
Semantic Scholar
Molecular Determinants of Pyrantel Selectivity in Nicotinic Receptors
M. Bartos, D. Rayes, C. Bouzat
2006Molecular Pharmacology26 citations Open access
Semantic Scholar
Key roles of hydrophobic rings of TM2 in gating of the α9α10 nicotinic cholinergic receptor
Paola V. Plazas, M. D. De Rosa, M. E. Gómez-Casati, M. Verbitsky +4 more
200526 citations Open access
Semantic Scholar
The noncompetitive inhibitor quinacrine modifies the desensitization kinetics of muscle acetylcholine receptors.
G. Spitzmaul, James P. Dilger, C. Bouzat
2001Molecular Pharmacology26 citations Open access
Semantic Scholar
Flavonoids as positive allosteric modulators of α7 nicotinic receptors.
B. E. Nielsen, I. Bermúdez, C. Bouzat
2019Neuropharmacology25 citations Open access
Semantic Scholar
Tricyclic antidepressants inhibit homomeric Cys-loop receptors by acting at different conformational states.
Fernanda Gumilar, C. Bouzat
2008European Journal of Pharmacology25 citations Open access
Semantic Scholar
Steroids differentially inhibit the nicotinic acetylcholine receptor
I. Garbus, C. Bouzat, F. Barrantes
2001NeuroReport25 citations Open access
Semantic Scholar
Diazepam treatment reduces inflammatory cells and mediators in the central nervous system of rats with experimental autoimmune encephalomyelitis.
Nicolás Fernández Hurst, S. Zanetti, Natalia S. Baez, Mario J. Bibolini +2 more
2017Journal of Neuroimmunology23 citations Open access
Semantic Scholar
The anthelmintic pyrantel acts as a low efficacious agonist and an open-channel blocker of mammalian acetylcholine receptors.
D. Rayes, M. J. De Rosa, G. Spitzmaul, C. Bouzat
2001Neuropharmacology22 citations Open access
Semantic Scholar
Regulation of nicotinic acetylcholine receptors by post-translational modifications.
Juan Facundo Chrestia, Ornella Turani, Noelia Rodriguez Araujo, Guillermina Hernando +2 more
2023Pharmacological Research21 citations Open access
Semantic Scholar
A Cys-loop Mutation in the Caenorhabditis elegans Nicotinic Receptor Subunit UNC-63 Impairs but Does Not Abolish Channel Function*
Andrew K. Jones, D. Rayes, A. Al-Diwani, T. Maynard +5 more
2010Journal of Biological Chemistry20 citations Open access
Semantic Scholar
Tyrosine phosphorylation differentially fine-tunes ionotropic and metabotropic responses of human α7 nicotinic acetylcholine receptor
Juan Facundo Chrestia, A. Bruzzone, María del Carmen Esandi, C. Bouzat
2021Cellular and Molecular Life Sciences19 citations Open access
Semantic Scholar
Unraveling Mechanisms Underlying Partial Agonism in 5-HT3A Receptors
J. Corradi, C. Bouzat
2014Journal of Neuroscience19 citations Open access
Semantic Scholar

Frequent co-authors

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J. Corradi×13
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J. Corradi — researcher profile on SciRah
D. Rayes×12
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D. Rayes — researcher profile on SciRah
S. Sine×10
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S. Sine — researcher profile on SciRah
María del Carmen Esandi×9
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María del Carmen Esandi — researcher profile on SciRah

Fernanda Gumilar

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Fernanda Gumilar — researcher profile on SciRah

G. Spitzmaul×7

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G. Spitzmaul — researcher profile on SciRah

Guillermina Hernando×7

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Guillermina Hernando — researcher profile on SciRah

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M. Bartos — researcher profile on SciRah

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H. Arias — researcher profile on SciRah

M. J. De Rosa×4

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M. J. De Rosa — researcher profile on SciRah

B. E. Nielsen×4

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B. E. Nielsen — researcher profile on SciRah

M. D. De Rosa×3

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M. D. De Rosa — researcher profile on SciRah