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N. Zwirner · SciRah

Researcher profile · Semantic Scholar

N. Zwirner

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N. Zwirner — researcher profile on SciRah

h-index: 30
Works: 71
Citations: 4,310

Most-cited papers

Differential glycosylation of TH1, TH2 and TH-17 effector cells selectively regulates susceptibility to cell death
M. Toscano, Germán A. Bianco, J. Ilarregui, D. Croci +7 more
2007Nature Immunology678 citations
Semantic Scholar
Targeted inhibition of galectin-1 gene expression in tumor cells results in heightened T cell-mediated rejection; A potential mechanism of tumor-immune privilege.
N. Rubinstein, Mariano J. Alvarez, N. Zwirner, M. Toscano +6 more
2004Cancer Cell565 citations Open access
Semantic Scholar
MICA, a new polymorphic HLA-related antigen, is expressed mainly by keratinocytes, endothelial cells, and monocytes
N. Zwirner, M. Fernández-Viña, P. Sťastný
1997Immunogenetics246 citations
Semantic Scholar
Identification of MICA as a new polymorphic alloantigen recognized by antibodies in sera of organ transplant recipients.
N. Zwirner, C. Y. Marcos, F. Mirbaha, Yi-Zhou Zou +1 more
2000Human Immunology190 citations Open access
Semantic Scholar
Differential surface expression of MICA by endothelial cells, fibroblasts, keratinocytes, and monocytes.
N. Zwirner, Karyn Dole, Peter Stastny
1999Human Immunology187 citations
Semantic Scholar
Cytokine regulation of natural killer cell effector functions
N. Zwirner, Carolina I. Domaica
2010Biofactors179 citations
Semantic Scholar
Leveraging NKG2D Ligands in Immuno-Oncology
M. Fuertes, C. Domaica, N. Zwirner
2021Frontiers in Immunology135 citations Open access
Semantic Scholar
Regulation of NK Cell Activation and Effector Functions by the IL-12 Family of Cytokines: The Case of IL-27
N. Zwirner, A. Ziblat
2017Frontiers in Immunology126 citations Open access
Semantic Scholar
Engagement of TLR3, TLR7, and NKG2D Regulate IFN-γ Secretion but Not NKG2D-Mediated Cytotoxicity by Human NK Cells Stimulated with Suboptimal Doses of IL-121
M. Girart, M. Fuertes, C. Domaica, L. Rossi +1 more
2007Journal of Immunology121 citations Open access
Semantic Scholar
Intracellular Retention of the NKG2D Ligand MHC Class I Chain-Related Gene A in Human Melanomas Confers Immune Privilege and Prevents NK Cell-Mediated Cytotoxicity1
M. Fuertes, M. Girart, L. Molinero, C. Domaica +5 more
2008Journal of Immunology115 citations Open access
Semantic Scholar
NK Cells Restrain Spontaneous Antitumor CD8+ T Cell Priming through PD-1/PD-L1 Interactions with Dendritic Cells
X. Raffo-Iraolagoitia, R. Spallanzani, Nicolás I Torres, R. Araya +8 more
2016Journal of Immunology103 citations Open access
Semantic Scholar
NF-κB Regulates Expression of the MHC Class I-Related Chain A Gene in Activated T Lymphocytes1
L. Molinero, M. Fuertes, M. Girart, L. Fainboim +3 more
2004Journal of Immunology100 citations Open access
Semantic Scholar
Cytokine-driven regulation of NK cell functions in tumor immunity: role of the MICA-NKG2D system.
N. Zwirner, M. Fuertes, M. Girart, C. Domaica +1 more
2007Cytokine & growth factor reviews96 citations
Semantic Scholar
Human M2 Macrophages Limit NK Cell Effector Functions through Secretion of TGF-β and Engagement of CD85j
S. Y. Nuñez, A. Ziblat, Florencia Secchiari, Nicolás I Torres +6 more
2018Journal of Immunology87 citations Open access
Semantic Scholar
Activation‐induced expression of MICA on T lymphocytes involves engagement of CD3 and CD28
L. Molinero, M. Fuertes, G. Rabinovich, L. Fainboim +1 more
2002Journal of Leukocyte Biology87 citations Open access
Semantic Scholar
Cross‐reactivity studies and differential serodiagnosis of human infections caused by Trypanosoma cruzi and Leishmania spp; use of immunoblotting and ELISA with a purified antigen (Ag163B6)
E. Malchiodi, M. Chiaramonte, N. Taranto, N. Zwirner +1 more
1994Clinical and Experimental Immunology87 citations Open access
Semantic Scholar
Regulated expression of galectin-1 during T-cell activation involves Lck and Fyn kinases and signaling through MEK1/ERK, p38 MAP kinase and p70S6 kinase
M. Fuertes, L. Molinero, M. Toscano, J. Ilarregui +4 more
2004Molecular and Cellular Biochemistry83 citations
Semantic Scholar
IL‐27 stimulates human NK‐cell effector functions and primes NK cells for IL‐18 responsiveness
A. Ziblat, Carolina I. Domaica, Raúl G. Spallanzani, X. L. Raffo Iraolagoitia +5 more
2015European Journal of Immunology81 citations Open access
Semantic Scholar
Histone deacetylase inhibitors impair NK cell viability and effector functions through inhibition of activation and receptor expression
L. Rossi, Damián E. Ávila, Raúl G. Spallanzani, A. Ziblat +6 more
2012Journal of Leukocyte Biology81 citations Open access
Semantic Scholar
NF-kappa B regulates expression of the MHC class I-related chain A gene in activated T lymphocytes.
L. Molinero, M. Fuertes, M. Girart, L. Fainboim +3 more
2004Journal of Immunology59 citations
Semantic Scholar
Nuclear factor (NF)-κB controls expression of the immunoregulatory glycan-binding protein galectin-1.
M. Toscano, L. Campagna, L. Molinero, J. Cerliani +8 more
2011Molecular Immunology57 citations Open access
Semantic Scholar
Interleukin (IL)-23 Stimulates IFN-γ Secretion by CD56bright Natural Killer Cells and Enhances IL-18-Driven Dendritic Cells Activation
A. Ziblat, S. Y. Nuñez, X. L. Raffo Iraolagoitia, R. Spallanzani +6 more
2018Frontiers in Immunology48 citations Open access
Semantic Scholar
Expression and Functional Role of α7 Nicotinic Receptor in Human Cytokine-stimulated Natural Killer (NK) Cells*
S. Zanetti, A. Ziblat, Nicolás I Torres, N. Zwirner +1 more
2016Journal of Biological Chemistry47 citations Open access
Semantic Scholar
Broad MICA/B Expression in the Small Bowel Mucosa: A Link between Cellular Stress and Celiac Disease
Y. Allegretti, C. Bondar, L. Guzmán, Eduardo Cueto Rua +4 more
2013PLoS ONE44 citations Open access
Semantic Scholar
Intracellular expression of MICA in activated CD4 T lymphocytes and protection from NK cell-mediated MICA-dependent cytotoxicity.
L. Molinero, C. Domaica, M. Fuertes, M. Girart +2 more
2006Human Immunology42 citations Open access
Semantic Scholar
Trypanosoma cruzi and Leishmania spp. human mixed infection.
M. Chiaramonte, N. Zwirner, S. Caropresi, N. Taranto +1 more
1996American Journal of Tropical Medicine and Hygiene41 citations
Semantic Scholar
Regulatory functions of NK cells during infections and cancer
N. Zwirner, C. Domaica, M. Fuertes
2020Journal of Leukocyte Biology36 citations Open access
Semantic Scholar
Tumor-Experienced Human NK Cells Express High Levels of PD-L1 and Inhibit CD8+ T Cell Proliferation
Jessica Sierra, Florencia Secchiari, S. Y. Nuñez, X. Raffo-Iraolagoitia +16 more
2021Frontiers in Immunology35 citations Open access
Semantic Scholar
Up‐regulated expression of MICA on activated T lymphocytes involves Lck and Fyn kinases and signaling through MEK1/ERK, p38 MAP kinase, and calcineurin
L. Molinero, M. Fuertes, L. Fainboim, G. Rabinovich +1 more
2003Journal of Leukocyte Biology34 citations Open access
Semantic Scholar
Regulatory Dendritic Cells Restrain NK Cell IFN-γ Production through Mechanisms Involving NKp46, IL-10, and MHC Class I–Specific Inhibitory Receptors
R. Spallanzani, Nicolás I Torres, Damián E. Ávila, A. Ziblat +6 more
2015Journal of Immunology32 citations Open access
Semantic Scholar
Restoration of antitumor immunity through anti-MICA antibodies elicited with a chimeric protein
Nicolás I Torres, M. V. Regge, Florencia Secchiari, A. Friedrich +18 more
2020Journal for ImmunoTherapy of Cancer28 citations Open access
Semantic Scholar
Tumour‐experienced T cells promote NK cell activity through trogocytosis of NKG2D and NKp46 ligands
Carolina I. Domaica, M. Fuertes, L. Rossi, M. Girart +3 more
2009EMBO Reports28 citations Open access
Semantic Scholar
Circulating and Tumor-Infiltrating NK Cells From Clear Cell Renal Cell Carcinoma Patients Exhibit a Predominantly Inhibitory Phenotype Characterized by Overexpression of CD85j, CD45, CD48 and PD-1
A. Ziblat, X. L. R. Iraolagoitia, S. Y. Nuñez, Nicolás I Torres +8 more
2021Frontiers in Immunology27 citations Open access
Semantic Scholar
STAT5B restrains human B-cell differentiation to maintain humoral immune homeostasis.
Simon J. Pelham, M. Caldirola, D. Avery, J. Mackie +25 more
2022Journal of Allergy and Clinical Immunology26 citations Open access
Semantic Scholar
Human Natural Killer Cell Maturation Defect Supports In Vivo CD56bright to CD56dim Lineage Development
C. Domaica, M. Fuertes, I. Uriarte, M. Girart +6 more
2012PLoS ONE26 citations Open access
Semantic Scholar
Overcoming the hurdles of tumor immunity by targeting regulatory pathways in innate and adaptive immune cells.
N. Zwirner, D. Croci, C. Domaica, G. Rabinovich
2010Current pharmaceutical design25 citations
Semantic Scholar
Expansion of CD11b+Ly6G+Ly6Cint cells driven by medroxyprogesterone acetate in mice bearing breast tumors restrains NK cell effector functions
R. Spallanzani, Tomás Dalotto-Moreno, X. L. Raffo Iraolagoitia, A. Ziblat +8 more
2013Cancer Immunology and Immunotherapy23 citations Open access
Semantic Scholar
Cloning, expression and interaction of human T-cell receptors with the bacterial superantigen SSA.
M. De Marzi, M. Fernández, E. Sundberg, L. Molinero +4 more
2004European Journal of Biochemistry22 citations Open access
Semantic Scholar
Up-regulated expression of MICA and proinflammatory cytokines in skin biopsies from patients with seborrhoeic dermatitis.
L. Molinero, M. Gruber, J. Leoni, A. Woscoff +1 more
2003Clinical Immunology22 citations
Semantic Scholar
A lytic monoclonal antibody to Trypanosoma cruzi bloodstream trypomastigotes which recognizes an epitope expressed in tissues affected in Chagas' disease
N. Zwirner, E. L. Malchiodi, M. Chiaramonte, Carlos A. Fossati
1994Infection and Immunity22 citations Open access
Semantic Scholar
Primary Immunodeficiencies Unravel the Role of IL-2/CD25/STAT5b in Human Natural Killer Cell Maturation
M. Caldirola, María Guadalupe Rodríguez Broggi, M. Gaillard, L. Bezrodnik +1 more
2018Frontiers in Immunology21 citations Open access
Semantic Scholar
Modulation of cardiac physiology by an anti‐Trypanosoma cruzi monoclonal antibody after interaction with myocardium
G. Cremaschi, N. Zwirner, G. Gorelik, E. L. Malchiodi +3 more
1995The FASEB Journal21 citations
Semantic Scholar
Immunobiology of the human MHC class I chain-related gene A (MICA): from transplantation immunology to tumor immune escape
N. Zwirner, M. Fuertes, M. Girart, C. Domaica +1 more
200620 citations
Semantic Scholar
Oryzomys Flavescens and O. Delticola Chromosomes (Rodentia, Cricetidae) from Uruguay and Argentina
N. Brum-Zorrilla, T. G. de Fronza, R. Wainberg, L. V. Rioja +1 more
198820 citations Open access
Semantic Scholar
Immune Monitoring of Patients With Primary Immune Regulation Disorders Unravels Higher Frequencies of Follicular T Cells With Different Profiles That Associate With Alterations in B Cell Subsets
M. Caldirola, María P Martínez, L. Bezrodnik, N. Zwirner +1 more
2020Frontiers in Immunology19 citations Open access
Semantic Scholar
Predictive Outcomes for HER2-enriched Cancer Using Growth and Metastasis Signatures Driven By SPARC
Leandro N. Güttlein, L. Benedetti, C. Fresno, R. Spallanzani +10 more
2016Molecular Cancer Research18 citations Open access
Semantic Scholar
Identity of the major cysteine proteinase (cruzipain) from Trypanosoma cruzi and an antigen (Ag163B6) isolated with a monoclonal antibody.
E. Malchiodi, M. Chiaramonte, J. Martínez, N. Zwirner +2 more
1993Immunology Letters16 citations
Semantic Scholar
[Study of cases of leishmaniasis in the Province of Salta: evidences of mixed infection with Trypanosoma cruzi and Leishmania spp].
M. Chiaramonte, N. Zwirner, S. Caropresi, V. Heredia +2 more
1996Medicina15 citations
Semantic Scholar
The MICA-NKG2D axis in clear cell renal cell carcinoma bolsters MICA as target in immuno-oncology
Florencia Secchiari, S. Y. Nuñez, Jessica Sierra, A. Ziblat +18 more
2022Oncoimmunology14 citations Open access
Semantic Scholar
Modulatory effects on myocardial physiology induced by an anti-Trypanosoma cruzi monoclonal antibody involve recognition of major antigenic epitopes from beta1-adrenergic and M2-muscarinic cholinergic receptors without requiring receptor cross-linking.
G. Cremaschi, M. Fernández, G. Gorelik, J. C. Goin +3 more
2004Journal of Neuroimmunology14 citations
Semantic Scholar

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M. Fuertes×27
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M. Fuertes — researcher profile on SciRah
C. Domaica×18
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C. Domaica — researcher profile on SciRah
G. Rabinovich×13
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G. Rabinovich — researcher profile on SciRah
A. Ziblat×13
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Jessica Sierra — researcher profile on SciRah

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