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M. Mattmann · SciRah

Researcher profile · Semantic Scholar

M. Mattmann

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M. Mattmann — researcher profile on SciRah

h-index: 16
Works: 28
Citations: 1,333

Most-cited papers

Modulation of bacterial quorum sensing with synthetic ligands: systematic evaluation of N-acylated homoserine lactones in multiple species and new insights into their mechanisms of action.
G. Geske, Jennifer C. O'Neill, David M. Miller, M. Mattmann +1 more
2007Journal of the American Chemical Society226 citations Open access
Semantic Scholar
Small Molecules that Modulate Quorum Sensing and Control Virulence in Pseudomonas aeruginosa
M. Mattmann, H. Blackwell
2010Journal of Organic Chemistry117 citations Open access
Semantic Scholar
Isovaleryl-homoserine lactone, an unusual branched-chain quorum-sensing signal from the soybean symbiont Bradyrhizobium japonicum
A. Lindemann, Gabriella Pessi, A. Schaefer, M. Mattmann +6 more
2011Proceedings of the National Academy of Sciences of the United States of America115 citations Open access
Semantic Scholar
Evaluation of a focused library of N-aryl L-homoserine lactones reveals a new set of potent quorum sensing modulators
G. Geske, M. Mattmann, H. Blackwell
2008Bioorganic & Medicinal Chemistry Letters96 citations Open access
Semantic Scholar
Comparative Analyses of N‐Acylated Homoserine Lactones Reveal Unique Structural Features that Dictate Their Ability to Activate or Inhibit Quorum Sensing
G. Geske, Jennifer C. O'Neill, David M. Miller, Rachel J. Wezeman +3 more
2008ChemBioChem96 citations Open access
Semantic Scholar
Control of Quorum Sensing by a Burkholderia pseudomallei Multidrug Efflux Pump
Y. Chan, Hao-Sheng Bian, T. Tan, M. Mattmann +6 more
2007Journal of Bacteriology91 citations Open access
Semantic Scholar
Dynamic subunit stoichiometry confers a progressive continuum of pharmacological sensitivity by KCNQ potassium channels
Hai-Bo Yu, Zhi-Hong Lin, M. Mattmann, Bei-Yan Zou +8 more
2013Proceedings of the National Academy of Sciences of the United States of America80 citations Open access
Semantic Scholar
Identification of Positive Allosteric Modulators VU0155094 (ML397) and VU0422288 (ML396) Reveals New Insights into the Biology of Metabotropic Glutamate Receptor 7
N. Jalan-Sakrikar, Julie R. Field, Rebecca Klar, M. Mattmann +19 more
2014ACS Chemical Neuroscience70 citations Open access
Semantic Scholar
Synthetic ligands that activate and inhibit a quorum-sensing regulator in Pseudomonas aeruginosa.
M. Mattmann, G. Geske, G. A. Worzalla, Josephine R. Chandler +3 more
2008Bioorganic & Medicinal Chemistry Letters66 citations Open access
Semantic Scholar
Identification of (R)-N-(4-(4-methoxyphenyl)thiazol-2-yl)-1-tosylpiperidine-2-carboxamide, ML277, as a novel, potent and selective Kv7.1 (KCNQ1) potassium channel activator
M. Mattmann, Hai-Bo Yu, Zhi-Hong Lin, Kaiping Xu +9 more
2012Bioorganic & Medicinal Chemistry Letters65 citations Open access
Semantic Scholar
Inhibition of Akt with small molecules and biologics: historical perspective and current status of the patent landscape
M. Mattmann, Sydney L. Stoops, C. Lindsley
2011Expert Opinion on Therapeutic Patents63 citations Open access
Semantic Scholar
Potent and Selective Modulation of the RhlR Quorum Sensing Receptor using Non-Native Ligands – An Emerging Target for Virulence Control in Pseudomonas aeruginosa
N. Eibergen, Joseph D. Moore, M. Mattmann, H. Blackwell
2015ChemBioChem57 citations Open access
Semantic Scholar
Potent and Selective Synthetic Modulators of a Quorum Sensing Repressor in Pseudomonas aeruginosa Identified from Second-Generation Libraries of N-Acylated l-Homoserine Lactones
M. Mattmann, Patrick M. Shipway, N. Heth, H. Blackwell
2011ChemBioChem56 citations Open access
Semantic Scholar
Recent progress in the discovery of small molecules for the treatment of amyotrophic lateral sclerosis (ALS)
A. Limpert, M. Mattmann, N. Cosford
2013Beilstein Journal of Organic Chemistry36 citations Open access
Semantic Scholar
Isatin replacements applied to the highly selective, muscarinic M1 PAM ML137: Continued optimization of an MLPCN probe molecule
B. Melancon, M. Poslusney, P. R. Gentry, J. C. Tarr +9 more
2012Bioorganic & Medicinal Chemistry Letters21 citations Open access
Semantic Scholar
An integrated chemical biology approach reveals the mechanism of action of HIV replication inhibitors
Nicholas Pagano, P. Teriete, M. Mattmann, Li Yang +4 more
2017Bioorganic & Medicinal Chemistry18 citations Open access
Semantic Scholar
Autoinducer-Fluorophore Conjugates Enable FRET in LuxR Proteins in Vitro and in Cells
Matthew Q Styles, M. Boursier, M. McEwan, Emma E. Santa +3 more
2022Nature Chemical Biology16 citations Open access
Semantic Scholar
Heterotropic Activation of the Midazolam Hydroxylase Activity of CYP3A by a Positive Allosteric Modulator of mGlu5: In Vitro to In Vivo Translation and Potential Impact on Clinically Relevant Drug-Drug Interactions
A. L. Blobaum, T. M. Bridges, Frank W. Byers, Mark Turlington +13 more
2013Drug Metabolism And Disposition16 citations Open access
Semantic Scholar
Development of novel M1 antagonist scaffolds through the continued optimization of the MLPCN probe ML012
B. Melancon, T. J. Utley, Christian Sevel, M. Mattmann +9 more
2012Bioorganic & Medicinal Chemistry Letters14 citations Open access
Semantic Scholar
Identification of a novel, small molecule activator of KCNQ1 channels
Hai-Bo Yu, Zhi-Hong Lin, Kaiping Xu, Xiaofang Huang +10 more
201310 citations
Semantic Scholar
Abstract 2758: Comparison of cell-free DNA blood collection tubes
C. D. Browne, M. Mattmann, Marc J. Wycoco, Sheila N. Chen +6 more
20173 citations
Semantic Scholar
Control of Quorum Sensing by a Burkholderia pseudomallei Multidrug Efﬂux Pump (cid:1)
Y. Chan, Hao-Sheng Bian, T. Tan, M. Mattmann +6 more
20073 citations
Semantic Scholar
Reversible, Orally Bioavailable Small-Molecule Inhibitors Occupy the Substrate Tunnel of the Thioesterase Domain of Fatty Acid Synthase
Joseph Fromm, A. Aleshin, Lester J. Lambert, L. D. De Backer +14 more
2026bioRxiv0 citations Open access
Semantic Scholar
QUORUM SENSING IN BACTERIAL VIRULENCE AND POSSIBILITIES FOR ITS CONTROL: A REVIEW
Das Rk, R. Teresa, De Kievit, H. Barbara +169 more
2020International Journal of Biology Pharmacy and Allied Sciences0 citations Open access
Semantic Scholar
Réduction de vitesse de sédimentation des érythrocytes
Joel Desharnais, V. Arendt, M. Mattmann
20160 citations
Semantic Scholar
Selective inhibitors of FAS-TE
R. Ardecky, M. Hedrick, Palak Gosalia, Fusayo Yamamoto +26 more
20140 citations
Semantic Scholar
Microsoft Word-JSD_3A4_activation_mGlu5_PAM_revised_final_V4[1]
A. L. Blobaum, T. M. Bridges, Frank W. Byers, M. Turlington +14 more
20130 citations
Semantic Scholar
DMD052662 2066..2075
A. L. Blobaum, T. M. Bridges, Frank W. Byers, M. Turlington +13 more
20130 citations
Semantic Scholar

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