Researcher profile · Semantic Scholar

N. Shukeir

h-index: 14
Works: 25
Citations: 1,905

Most-cited papers

Prdm3 and Prdm16 are H3K9me1 methyltransferases required for mammalian heterochromatin integrity.
Inês Pinheiro, R. Margueron, N. Shukeir, Michael Eisold +10 more
2012Cell328 citations Open access
Semantic Scholar
Up-regulation of Wnt-1 and beta-catenin production in patients with advanced metastatic prostate carcinoma: potential pathogenetic and prognostic implications.
Gaoping Chen, N. Shukeir, A. Potti, K. Sircar +3 more
2004Cancer300 citations
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Histone demethylase UTX-1 regulates C. elegans life span by targeting the insulin/IGF-1 signaling pathway.
Chunyu Jin, Jing Li, Christopher D. Green, Xiao-Ming Yu +15 more
2011Cell Metabolism231 citations Open access
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A transcription factor–based mechanism for mouse heterochromatin formation
Aydan Bulut-Karslioglu, V. Perrera, Manuela Scaranaro, I. A. de la Rosa-Velázquez +11 more
2012Nature Structural &Molecular Biology184 citations
Semantic Scholar
Major satellite repeat RNA stabilize heterochromatin retention of Suv39h enzymes by RNA-nucleosome association and RNA:DNA hybrid formation
Oscar Velazquez Camacho, Carmen Galán, Kalina M. Świst-Rosowska, R. Ching +9 more
2017eLife169 citations Open access
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Alteration of the methylation status of tumor-promoting genes decreases prostate cancer cell invasiveness and tumorigenesis in vitro and in vivo.
N. Shukeir, Pouya Pakneshan, Gaoping Chen, M. Szyf +1 more
2006Cancer Research168 citations Open access
Semantic Scholar
Mammalian Su(var) genes in chromatin control.
B. Fodor, N. Shukeir, G. Reuter, T. Jenuwein
2010Annual Review of Cell and Developmental Biology106 citations
Semantic Scholar
Complete loss of H3K9 methylation dissolves mouse heterochromatin organization
Thomas Montavon, N. Shukeir, Galina A. Erikson, Bettina Engist +7 more
2021Nature Communications104 citations Open access
Semantic Scholar
Prostate secretory protein PSP-94 decreases tumor growth and hypercalcemia of malignancy in a syngenic in vivo model of prostate cancer.
N. Shukeir, A. Arakelian, Salam Kadhim, S. Garde +1 more
2003Cancer Research86 citations
Semantic Scholar
H1 linker histones silence repetitive elements by promoting both histone H3K9 methylation and chromatin compaction
Sean E. Healton, Hugo D. Pinto, Laxmi N. Mishra, Gregory A. Hamilton +8 more
2020Proceedings of the National Academy of Sciences of the United States of America82 citations Open access
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A Synthetic 15-mer Peptide (PCK3145) Derived from Prostate Secretory Protein Can Reduce Tumor Growth, Experimental Skeletal Metastases, and Malignancy-Associated Hypercalcemia
N. Shukeir, A. Arakelian, Gaoping Chen, S. Garde +3 more
2004Cancer Research43 citations
Semantic Scholar
m6A RNA methylation of major satellite repeat transcripts facilitates chromatin association and RNA:DNA hybrid formation in mouse heterochromatin
Katarzyna J. Duda, R. Ching, Lisa Jerabek, N. Shukeir +11 more
2021Nucleic Acids Research35 citations Open access
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Pharmacological methyl group donors block skeletal metastasis in vitro and in vivo
N. Shukeir, B. Stefańska, Surabhi Parashar, Flora Chik +3 more
2015British Journal of Pharmacology34 citations Open access
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Up‐regulation of Wnt‐1 and β‐catenin production in patients with advanced metastatic prostate carcinoma
Gaoping Chen, N. Shukeir, A. Potti, K. Sircar +3 more
200416 citations
Semantic Scholar
Prostate secretory protein of 94 amino acids (PSP-94) and its peptide (PCK3145) as potential therapeutic modalities for prostate cancer
N. Shukeir, S. Garde, Jinzi J. Wu, C. Panchal +1 more
2005Anti-Cancer Drugs14 citations
Semantic Scholar
Transcriptional competence defines the heterochromatin nucleating potential of isolated MSR units
Y. Lo, N. Shukeir, Galina Erikson, Raghu R. Edupuganti +5 more
2026Nature Communications4 citations Open access
Semantic Scholar
A transcription factor–based mechanism for mouse heterochromatin formation
Aydan Bulut-Karslioglu, V. Perrera, Manuela Scaranaro, I. A. de la Rosa-Velázquez +11 more
2013Nature Structural &Molecular Biology4 citations Open access
Semantic Scholar
The isoflavone genistein selectively stimulates major satellite repeat transcription in mouse heterochromatin
Thomas Fuhrmann, N. Shukeir, R. Ching, Galina Erikson +5 more
2025Epigenetics & Chromatin3 citations Open access
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Molecular markers of metastases in advanced stage adenocarcinoma of the prostate
A. Potti, Gaoping Chen, N. Shukeir, S. Rabbani +1 more
20051 citations
Semantic Scholar
PROSTATE CANCER: MODELS FOR DEVELOPING NOVEL THERAPEUTIC APPROACHES
S. Rabbani, N. Shukeir, A. Mazar
20041 citations
Semantic Scholar
Author response: Major satellite repeat RNA stabilize heterochromatin retention of Suv39h enzymes by RNA-nucleosome association and RNA:DNA hybrid formation
Oscar Velazquez Camacho, Carmen Galán, Kalina M. Świst-Rosowska, R. Ching +9 more
20170 citations Open access
Semantic Scholar
Inhibition of skeletal metastasis in prostate cancer growth by S-adenosylmethionine (SAM) and methyl binding domain protein 2 (MBD2) knockdown.
N. Shukeir, M. Szyf, S. Rabbani
20070 citations
Semantic Scholar
Inhibition of Wnt-1 in human prostate cancer cells blocks prostate cancer cell proliferation, invasion, growth and skeletal metastasis in vitro and in vivo
S. Rabbani, M. Valentino, Gaoping Chen, N. Shukeir +1 more
20060 citations
Semantic Scholar
Inhibition of angiogenesis and MMP-9 expression by PCK3145 is mediated through targeting of the Akt signaling pathway
N. Shukeir, S. Garde, A. Arakelian, Gaoping Chen +5 more
20060 citations
Semantic Scholar
Prostate cancer therapy
S. Rabbani, N. Shukeir, S. Garde, Jinzi J. Wu +1 more
20050 citations
Semantic Scholar

Megumi Onishi-Seebacher

×5

S. Garde×5

I. A. de la Rosa-Velázquez×4

Bettina Engist×4

A. Arakelian×4

Gerhard Mittler×3

M. Lachner×3

A. Potti×3