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K. McNagny · SciRah

Researcher profile · Semantic Scholar

K. McNagny

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K. McNagny — researcher profile on SciRah

h-index: 50
Works: 237
Citations: 14K

Most-cited papers

Modeling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids
Benjamin S. Freedman, Craig R. Brooks, Albert Q. Lam, Hong-Xia Fu +17 more
2015Nature Communications730 citations Open access
Semantic Scholar
Butyrate Shapes Immune Cell Fate and Function in Allergic Asthma
William Yip, M. Hughes, Yicong Li, A. Cait +3 more
2021Frontiers in Immunology167 citations Open access
Semantic Scholar
Perinatal antibiotic-induced shifts in gut microbiota have differential effects on inflammatory lung diseases.
Shannon L. Russell, Matthew J. Gold, L. Reynolds, B. Willing +8 more
2015Journal of Allergy and Clinical Immunology149 citations
Semantic Scholar
Gene-edited human kidney organoids reveal mechanisms of disease in podocyte development
Yong Kyun Kim, Ido Refaeli, Craig R. Brooks, Peifeng Jing +13 more
2017Stem Cells122 citations Open access
Semantic Scholar
SETD7 Controls Intestinal Regeneration and Tumorigenesis by Regulating Wnt/β-Catenin and Hippo/YAP Signaling.
M. Oudhoff, Mitchell Braam, S. Freeman, Denise Wong +15 more
2016Developmental Cell112 citations Open access
Semantic Scholar
DMSO Represses Inflammatory Cytokine Production from Human Blood Cells and Reduces Autoimmune Arthritis
I. Elisia, Hisae Nakamura, V. Lam, Elyse Hofs +10 more
2016PLoS ONE110 citations Open access
Semantic Scholar
The nucleotide-binding domain, leucine-rich repeat protein 3 inflammasome/IL-1 receptor I axis mediates innate, but not adaptive, immune responses after exposure to particulate matter under 10 μm.
J. Hirota, Matthew J. Gold, Paul Hiebert, Leigh G. Parkinson +8 more
2015American Journal of Respiratory Cell and Molecular Biology85 citations
Semantic Scholar
Podocalyxin enhances breast tumor growth and metastasis and is a target for monoclonal antibody therapy
Kimberly Snyder, M. Hughes, B. Hedberg, Jill Brandon +12 more
2015Breast Cancer Research70 citations Open access
Semantic Scholar
IL-22 Preserves Gut Epithelial Integrity and Promotes Disease Remission during Chronic Salmonella Infection
Bernard C. Lo, Samuel B. Shin, Diana Canals-Hernaez, Ido Refaeli +6 more
2019Journal of Immunology57 citations
Semantic Scholar
The orphan nuclear receptor RORα and group 3 innate lymphoid cells drive fibrosis in a mouse model of Crohn’s disease
Bernard C. Lo, Matthew J. Gold, M. Hughes, F. Antignano +4 more
2016Science immunology50 citations Open access
Semantic Scholar
Podocalyxin is required for maintaining blood–brain barrier function during acute inflammation
J. Cait, M. Hughes, Matthew R. Zeglinski, Allen W. Chan +11 more
2019Proceedings of the National Academy of Sciences of the United States of America46 citations Open access
Semantic Scholar
Impact of a CXCL12/CXCR4 Antagonist in Bleomycin (BLM) Induced Pulmonary Fibrosis and Carbon Tetrachloride (CCl4) Induced Hepatic Fibrosis in Mice
Leola N. Y. Chow, Petra Schreiner, Betina Y. Y. Ng, Bernard C. Lo +11 more
2016PLoS ONE44 citations Open access
Semantic Scholar
Macrophages with reduced expressions of classical M1 and M2 surface markers in human bronchoalveolar lavage fluid exhibit pro-inflammatory gene signatures
H. Takiguchi, C. Yang, Cheng Wei Tony Yang, B. Şahin +14 more
2021Scientific Reports43 citations Open access
Semantic Scholar
A Sticky Wicket: Defining Molecular Functions for CD34 in Hematopoietic Cells.
M. Hughes, D. C. Hernaez, J. Cait, Ido Refaeli +3 more
2020Experimental Hematology40 citations Open access
Semantic Scholar
The Transcription Factor RORα Preserves ILC3 Lineage Identity and Function during Chronic Intestinal Infection
Bernard C. Lo, Diana Canals-Hernaez, R. W. Scott, Michael R. Hughes +4 more
2019Journal of Immunology40 citations Open access
Semantic Scholar
G9a regulates group 2 innate lymphoid cell development by repressing the group 3 innate lymphoid cell program
F. Antignano, Mitchell Braam, M. Hughes, Alistair L. Chenery +10 more
2016Journal of Experimental Medicine38 citations Open access
Semantic Scholar
Pulmonary CD103 expression regulates airway inflammation in asthma.
Émilie Bernatchez, Matthew J. Gold, Anick Langlois, Anne‐Marie Lemay +5 more
2015American Journal of Physiology - Lung cellular and Molecular Physiology38 citations
Semantic Scholar
Mast cells promote small bowel cancer in a tumor stage-specific and cytokine-dependent manner
A. Saadalla, A. Osman, M. Gurish, Kristen L. Dennis +6 more
2018Proceedings of the National Academy of Sciences of the United States of America37 citations Open access
Semantic Scholar
Hedgehog signaling in the airway epithelium of patients with chronic obstructive pulmonary disease
A. Tam, M. Hughes, K. McNagny, M. Obeidat +10 more
2019Scientific Reports35 citations Open access
Semantic Scholar
ILC-You in the Thymus: A Fresh Look at Innate Lymphoid Cell Development
Samuel B. Shin, K. McNagny
2021Frontiers in Immunology33 citations Open access
Semantic Scholar
Group 2 Innate Lymphoid Cells: Central Players in a Recurring Theme of Repair and Regeneration
M. Messing, Sia C Jan-Abu, K. McNagny
2020International Journal of Molecular Sciences33 citations Open access
Semantic Scholar
The orphan nuclear receptor ROR alpha and group 3 innate lymphoid cells drive fibrosis in a mouse model of Crohn's disease.
Bernard C. Lo, Matthew J. Gold, M. Hughes, F. Antignano +4 more
2016Science immunology33 citations Open access
Semantic Scholar
Morphometric analysis of inflammation in bronchial biopsies following exposure to inhaled diesel exhaust and allergen challenge in atopic subjects
A. Hosseini, J. Hirota, T. Hackett, K. McNagny +2 more
2015Particle and Fibre Toxicology33 citations Open access
Semantic Scholar
Bacterial–fungal interactions in the neonatal gut influence asthma outcomes later in life
Rozlyn C. T. Boutin, Charisse Petersen, S. Woodward, A. Serapio-Palacios +16 more
2021eLife32 citations Open access
Semantic Scholar
The cell surface mucin podocalyxin regulates collective breast tumor budding
M. Graves, Jane A. Cipollone, P. Austin, Erin M. Bell +4 more
2016Breast Cancer Research32 citations Open access
Semantic Scholar
Loss of podocalyxin causes a novel syndromic type of congenital nephrotic syndrome
H. Kang, Moses Lee, K. Lee, M. Hughes +8 more
2017Experimental and Molecular Medicine30 citations Open access
Semantic Scholar
Microbial intestinal dysbiosis drives long-term allergic susceptibility by sculpting an ILC2-B1 cell-innate IgE axis.
Ahmed Kabil, Natalia Nayyar, Julyanne Brassard, Yicong Li +3 more
2024Journal of Allergy and Clinical Immunology29 citations Open access
Semantic Scholar
CD34 Promotes Pathological Epi-Retinal Neovascularization in a Mouse Model of Oxygen-Induced Retinopathy
M. Siemerink, M. Hughes, Marchien G. Dallinga, T. Gora +7 more
2016PLoS ONE28 citations Open access
Semantic Scholar
Neuroinflammation and the immune system in hypoxic ischaemic brain injury pathophysiology after cardiac arrest
M. Sekhon, S. Stukas, V. Hirsch-Reinshagen, S. Thiara +5 more
2023Journal of Physiology27 citations
Semantic Scholar
Platelet signaling at the nexus of innate immunity and rheumatoid arthritis
Steven Jiang, J. To, M. Hughes, K. McNagny +1 more
2022Frontiers in Immunology27 citations Open access
Semantic Scholar
In situ hematopoiesis: a regulator of TH2 cytokine-mediated immunity and inflammation at mucosal surfaces
C. Hui, K. McNagny, J. Denburg, M. Siracusa
2015Mucosal Immunology27 citations Open access
Semantic Scholar
IQCELL: A platform for predicting the effect of gene perturbations on developmental trajectories using single-cell RNA-seq data
Tiam Heydari, Matthew A. Langley, C. Fisher, Daniel Aguilar-Hidalgo +5 more
2021bioRxiv25 citations Open access
Semantic Scholar
Distinct Functional Requirements for Podocalyxin in Immature and Mature Podocytes Reveal Mechanisms of Human Kidney Disease
Ido Refaeli, M. Hughes, Alvin K. C. Wong, M. L. Bissonnette +5 more
2020Scientific Reports23 citations Open access
Semantic Scholar
HDAC2 Regulates Site-Specific Acetylation of MDM2 and Its Ubiquitination Signaling in Tumor Suppression
N. Patel, Jue Wang, Kumiko Shiozawa, Kevin B. Jones +19 more
2019iScience22 citations Open access
Semantic Scholar
PODO447: a novel antibody to a tumor-restricted epitope on the cancer antigen podocalyxin
Diana Canals-Hernaez, M. Hughes, Pamela Dean, P. Bergqvist +10 more
2020Journal for ImmunoTherapy of Cancer20 citations Open access
Semantic Scholar
Methanosphaera stadtmanae induces a type IV hypersensitivity response in a mouse model of airway inflammation
Émilie Bernatchez, Matthew J. Gold, Anick Langlois, P. Blais‐Lecours +5 more
2017Physiological Reports20 citations Open access
Semantic Scholar
The Aspergillus fumigatus Sialidase (Kdnase) Contributes to Cell Wall Integrity and Virulence in Amphotericin B-Treated Mice
Jason R. Nesbitt, Elizabeth Steves, Cole Schonhofer, A. Cait +7 more
2018Frontiers in Microbiology18 citations Open access
Semantic Scholar
Inhaled Corticosteroids Selectively Alter the Microbiome and Host Transcriptome in the Small Airways of Patients with Chronic Obstructive Pulmonary Disease
William Yip, Xuan Li, G. Koelwyn, S. Milne +11 more
2022Biomedicines17 citations Open access
Semantic Scholar
A Novel Germline Heterozygous BCL11B Variant Causing Severe Atopic Disease and Immune Dysregulation
Henry Y. Lu, Robert Sertori, A. Contreras, M. Hamer +10 more
2021Frontiers in Immunology16 citations Open access
Semantic Scholar
Chronic Trichuris muris infection alters hematopoiesis and causes IFN‐γ‐expressing T‐cell accumulation in the mouse bone marrow
Alistair L. Chenery, F. Antignano, M. Hughes, K. Burrows +2 more
2016European Journal of Immunology15 citations Open access
Semantic Scholar
Loss of Vascular CD34 Results in Increased Sensitivity to Lung Injury
Bernard C. Lo, Matthew J. Gold, Sebastian Scheer, M. Hughes +10 more
2017American Journal of Respiratory Cell and Molecular Biology14 citations Open access
Semantic Scholar
Dendritic‐cell expression of Ship1 regulates Th2 immunity to helminth infection in mice
Matthew J. Gold, F. Antignano, M. Hughes, C. Zaph +1 more
2016European Journal of Immunology14 citations
Semantic Scholar
Hedgehog Signaling as a Therapeutic Target for Airway Remodeling and Inflammation in Allergic Asthma
A. Tam, E. Osei, C. Cheung, M. Hughes +10 more
2022Cells13 citations Open access
Semantic Scholar
Parallel Origins and Functions of T Cells and Ilcs.
Sia C Jan-Abu, Ahmed Kabil, K. McNagny
2023Clinical and Experimental Immunology12 citations Open access
Semantic Scholar
“Just one word, plastic!”: Controversies and caveats in innate lymphoid cell plasticity
Ahmed Kabil, Samuel B. Shin, M. Hughes, K. McNagny
2022Frontiers in Immunology12 citations Open access
Semantic Scholar
Eosinophils Decrease Pulmonary Metastatic Mammary Tumor Growth
R. Cederberg, S. E. Franks, Brennan J. Wadsworth, A. So +6 more
2022Frontiers in Oncology12 citations Open access
Semantic Scholar
Lineage-specific regulation of allergic airway inflammation by the lipid phosphatase Src homology 2 domain-containing inositol 5-phosphatase (SHIP-1).
Matthew J. Gold, M. Hughes, F. Antignano, J. Hirota +2 more
2015Journal of Allergy and Clinical Immunology11 citations Open access
Semantic Scholar
Antibody-Drug Conjugates Targeting Tumor-Specific Mucin Glycoepitopes.
Julyanne Brassard, M. Hughes, C. Roskelley, K. McNagny
2022Frontiers in Bioscience10 citations Open access
Semantic Scholar
Platelet factor 4 (CXCL4/PF4) upregulates matrix metalloproteinase-2 (MMP-2) in gingival fibroblasts
H. T. Le, Kalyan Golla, Ryan Karimi, M. Hughes +7 more
2022Scientific Reports9 citations Open access
Semantic Scholar
Losartan metabolite EXP3179 is a unique blood pressure-lowering AT1R antagonist with direct, rapid endothelium-dependent vasoactive properties.
Elodie Sauge, D. Pechkovsky, N. D. Prasad Atmuri, Arash Y. Tehrani +12 more
2022Vascular pharmacology9 citations
Semantic Scholar

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