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M. Kreek · SciRah

Researcher profile · Semantic Scholar

M. Kreek

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M. Kreek — researcher profile on SciRah

h-index: 87
Works: 666
Citations: 32K

Most-cited papers

Current status of opioid addiction treatment and related preclinical research
M. Kreek, Brian Reed, E. Butelman
2019Science Advances96 citations Open access
Semantic Scholar
Multi-trait genome-wide association study of opioid addiction: OPRM1 and beyond
Nathan C. Gaddis, Ravi Mathur, Jesse A. Marks, Linran Zhou +44 more
2021Scientific Reports73 citations Open access
Semantic Scholar
Repeated Administration of Opra Kappa (LY2456302), a Novel, Short-Acting, Selective KOP-r Antagonist, in Persons with and without Cocaine Dependence
Brian Reed, E. Butelman, Rebecca S Fry, R. Kimani +1 more
2017Neuropsychopharmacology62 citations Open access
Semantic Scholar
Alterations of expression of inflammation/immune-related genes in the dorsal and ventral striatum of adult C57BL/6J mice following chronic oxycodone self-administration: A RNA sequencing study
Yong Zhang, Yupu Liang, O. Levran, M. Randesi +3 more
2017Psychopharmacology55 citations Open access
Semantic Scholar
Sex differences in responsiveness to the prescription opioid oxycodone in mice.
Devon Collins, Brian Reed, Yong Zhang, M. Kreek
2016Pharmacology, Biochemistry and Behavior53 citations
Semantic Scholar
Signaling properties of structurally diverse kappa opioid receptor ligands: towards in vitro models of in vivo responses.
Amelia D. Dunn, Brian Reed, José Erazo, Ariel Ben-Ezra +1 more
2019ACS Chemical Neuroscience49 citations
Semantic Scholar
Blockade of alcohol escalation and “relapse” drinking by pharmacological FAAH inhibition in male and female C57BL/6J mice
Yan Zhou, Benjamin I. Schwartz, Joanna I. Giza, S. Gross +2 more
2017Psychopharmacology47 citations Open access
Semantic Scholar
Effects of the novel relatively short-acting kappa opioid receptor antagonist LY2444296 in behaviors observed after chronic extended-access cocaine self-administration in rats
M. Valenza, E. Butelman, M. Kreek
2017Psychopharmacology45 citations Open access
Semantic Scholar
Oxycodone Self-Administration Induces Alterations in Expression of Integrin, Semaphorin and Ephrin Genes in the Mouse Striatum
V. Yuferov, Yong Zhang, Yupu Liang, Connie Zhao +2 more
2018Frontiers in Psychiatry37 citations Open access
Semantic Scholar
Chronic Oxycodone Self-administration Altered Reward-related Genes in the Ventral and Dorsal Striatum of C57BL/6J Mice: An RNA-seq Analysis.
Yong Zhang, Yupu Liang, M. Randesi, V. Yuferov +2 more
2018Neuroscience35 citations
Semantic Scholar
Structurally Related Kappa Opioid Receptor Agonists with Substantial Differential Signaling Bias: Neuroendocrine and Behavioral Effects in C57BL6 Mice
Amelia D. Dunn, Brian Reed, C. Guariglia, Alexandra M. Dunn +2 more
2018International Journal of Neuropsychopharmacology34 citations Open access
Semantic Scholar
Adolescent oxycodone self administration alters subsequent oxycodone-induced conditioned place preference and anti-nociceptive effect in C57BL/6J mice in adulthood
Yong Zhang, Kyle A. Windisch, J. Altschuler, S. Rahm +2 more
2016Neuropharmacology34 citations Open access
Semantic Scholar
Impact of Pharmacological Manipulation of the κ-Opioid Receptor System on Self-grooming and Anhedonic-like Behaviors in Male Mice
E. Butelman, Bryan D. McElroy, T. Prisinzano, M. Kreek
2019Journal of Pharmacology and Experimental Therapeutics33 citations Open access
Semantic Scholar
Sex differences after chronic stress in the expression of opioid-, stress- and neuroplasticity-related genes in the rat hippocampus
M. Randesi, Yan Zhou, Sanoara Mazid, S. Odell +5 more
2018Neurobiology of Stress31 citations Open access
Semantic Scholar
Sex differences in the rat hippocampal opioid system after oxycodone conditioned place preference
J. Ryan, Yan Zhou, Natalina H. Contoreggi, Farah Bshesh +6 more
2018Neuroscience29 citations Open access
Semantic Scholar
Medications for substance use disorders (SUD): Emerging approaches
E. Butelman, M. Kreek
2017Expert Opinion on Emerging Drugs26 citations Open access
Semantic Scholar
Sex differences in neuroplasticity- and stress-related gene expression and protein levels in the rat hippocampus following oxycodone conditioned place preference
M. Randesi, Natalina H. Contoreggi, Yan Zhou, Batsheva Reich +6 more
2019Neuroscience25 citations Open access
Semantic Scholar
Preclinical Studies on Nalfurafine (TRK-820), a Clinically Used KOR Agonist
Yan Zhou, K. Freeman, V. Setola, Danni Cao +3 more
2021Handbook of Experimental Pharmacology23 citations Open access
Semantic Scholar
Review of addiction risk potential associated with adolescent opioid use.
Kyle A. Windisch, M. Kreek
2020Pharmacology, Biochemistry and Behavior22 citations
Semantic Scholar
Combination of clinically utilized kappa opioid receptor agonist nalfurafine with low-dose naltrexone reduces excessive alcohol drinking in male and female mice
Yan Zhou, M. Kreek
2019Alcoholism: Clinical and Experimental Research22 citations Open access
Semantic Scholar
Sex differences in the effect of bupropion and naltrexone combination on alcohol drinking in mice
Yan Zhou, F. Leri, M. Low, M. Kreek
2019Pharmacology, Biochemistry and Behavior21 citations Open access
Semantic Scholar
Synergistic blockade of alcohol escalation drinking in mice by a combination of novel kappa opioid receptor agonist Mesyl Salvinorin B and naltrexone
Yan Zhou, R. Crowley, Konrad T. Ben, T. Prisinzano +1 more
2017Brain Research21 citations Open access
Semantic Scholar
Hypothalamic-specific proopiomelanocortin-deficiency reduces alcohol drinking in male and female mice
Yan Zhou, Marcelo Rubinstein, Malcolm J. Low, M. Kreek
2017Genes, Brain and Behavior21 citations Open access
Semantic Scholar
Chronic stress differentially alters mRNA expression of opioid peptides and receptors in the dorsal hippocampus of female and male rats
Megan A. Johnson, Natalina H. Contoreggi, Joshua F. Kogan, Matthew Bryson +5 more
2021The Journal of comparative neurology20 citations Open access
Semantic Scholar
Design, synthesis, and preliminary evaluation of a potential synthetic opioid rescue agent
Sidnee L. Hedrick, D. Luo, Sophia Kaska, K. K. Niloy +8 more
2021Journal of Biomedical Sciences20 citations Open access
Semantic Scholar
Modulation of cocaine-related behaviors by low doses of the potent KOR agonist nalfurafine in male C57BL6 mice
Amelia D. Dunn, Kyle A. Windisch, Ariel Ben-Ezra, P. Pikus +4 more
2020Psychopharmacology19 citations
Semantic Scholar
The μ-opioid receptor nonsynonymous variant 118A>G is associated with prolonged abstinence from heroin without agonist treatment.
O. Levran, E. Peles, M. Randesi, J. D. da Rosa +2 more
2017Pharmacogenomics (London)19 citations Open access
Semantic Scholar
V1b receptor antagonist SSR149415 and naltrexone synergistically decrease excessive alcohol drinking in male and female mice
Yan Zhou, M. Rubinstein, M. Low, M. Kreek
2017Alcoholism: Clinical and Experimental Research19 citations Open access
Semantic Scholar
Involvement of Activated Brain Stress Responsive Systems in Excessive and “Relapse” Alcohol Drinking in Rodent Models: Implications for Therapeutics
Yan Zhou, M. Kreek
2018Journal of Pharmacology and Experimental Therapeutics18 citations Open access
Semantic Scholar
Dopamine gene variants in opioid addiction: comparison of dependent patients, nondependent users and healthy controls.
M. Randesi, W. J. van den Brink, O. Levran, V. Yuferov +4 more
2018Pharmacogenomics (London)18 citations Open access
Semantic Scholar
Effects of Kappa opioid receptor blockade by LY2444296 HCl, a selective short-acting antagonist, during chronic extended access cocaine self-administration and re-exposure in rat
M. Valenza, Kyle A. Windisch, E. Butelman, Brian Reed +1 more
2020Psychopharmacology17 citations
Semantic Scholar
Escalation of drug use in persons dually diagnosed with opioid and cocaine dependence: Gender comparison and dimensional predictors
E. Butelman, Carina Y. Chen, Kate G. Brown, M. Kreek
2019Drug and Alcohol Dependence17 citations Open access
Semantic Scholar
Kappa Opioid Receptor Antagonists as Potential Therapeutics for Mood and Substance Use Disorders.
Brian Reed, E. Butelman, M. Kreek
2020Handbook of Experimental Pharmacology16 citations
Semantic Scholar
Sex and chronic stress differentially alter phosphorylated mu and delta opioid receptor levels in the rat hippocampus following oxycodone conditioned place preference
Julia R. Bellamy, Batsheva R. Rubin, Angelica Zverovich, Yan Zhou +5 more
2019Neuroscience Letters15 citations Open access
Semantic Scholar
Nalfurafine modulates the reinforcing effects of oxycodone in male and female adolescent C57BL/6J mice.
Yong Zhang, M. Kreek
2020Neuropharmacology14 citations
Semantic Scholar
Chronic immobilization stress primes the hippocampal opioid system for oxycodone associated learning in female but not male rats
Batsheva Reich, Yan Zhou, Ellen Goldstein, Sudarshan S Srivats +6 more
2019Synapse14 citations
Semantic Scholar
Opioid receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database
A. Borsodi, M. Bruchas, G. Calo, C. Chavkin +26 more
2019IUPHAR/BPS Guide to Pharmacology CITE14 citations Open access
Semantic Scholar
VMAT2 gene (SLC18A2) variants associated with a greater risk for developing opioid dependence.
M. Randesi, W. J. van den Brink, O. Levran, P. Blanken +3 more
2019Pharmacogenomics (London)14 citations Open access
Semantic Scholar
Re-evaluation of the KMSK scales, rapid dimensional measures of self-exposure to specific drugs: Gender-specific features.
E. Butelman, Carina Y. Chen, Rebecca S Fry, R. Kimani +4 more
2018Drug and Alcohol Dependence14 citations
Semantic Scholar
Effects of Mesyl Salvinorin B alone and in combination with naltrexone on alcohol deprivation effect in male and female mice
Yan Zhou, R. Crowley, T. Prisinzano, M. Kreek
2018Neuroscience Letters14 citations Open access
Semantic Scholar
Nuclear transcriptional changes in hypothalamus of Pomc enhancer knockout mice after excessive alcohol drinking
Yan Zhou, Yupu Liang, M. Low, M. Kreek
2019Genes, Brain and Behavior13 citations Open access
Semantic Scholar
A non-coding CRHR2 SNP rs255105, a cis-eQTL for a downstream lincRNA AC005154.6, is associated with heroin addiction
O. Levran, J. C. Corrêa da Rosa, M. Randesi, J. Rotrosen +2 more
2018PLoS ONE13 citations Open access
Semantic Scholar
Endogenous opioid system in addiction and addiction-related behaviors
Brian Reed, E. Butelman, M. Kreek
201713 citations
Semantic Scholar
OPRD1 SNPs associated with opioid addiction are cis-eQTLs for the phosphatase and actin regulator 4 gene, PHACTR4, a mediator of cytoskeletal dynamics
O. Levran, M. Randesi, M. Adelson, M. Kreek
2021Translational Psychiatry12 citations Open access
Semantic Scholar
Genetic Vulnerability to Opioid Addiction.
Brian Reed, M. Kreek
2020Cold Spring Harbor Perspectives in Medicine12 citations Open access
Semantic Scholar
Are trait impulsivity and exposure to cannabis or alcohol associated with the age of trajectory of cocaine use? A gender-specific dimensional analysis in humans with cocaine dependence diagnosis.
E. Butelman, Carina Y. Chen, Rachel Conybeare, Kate G. Brown +5 more
2020Experimental and clinical psychopharmacology12 citations Open access
Semantic Scholar
Genetic variations in genes of the stress response pathway are associated with prolonged abstinence from heroin.
O. Levran, E. Peles, M. Randesi, J. C. Corrêa da Rosa +4 more
2018Pharmacogenomics (London)12 citations Open access
Semantic Scholar
Naltrexone and nalmefene attenuate cocaine place preference in male mice
Kyle A. Windisch, Brian Reed, M. Kreek
2018Neuropharmacology12 citations
Semantic Scholar
Non-medical Cannabis Self-Exposure as a Dimensional Predictor of Opioid Dependence Diagnosis: A Propensity Score Matched Analysis
E. Butelman, A. Maremmani, S. Bacciardi, Carina Y. Chen +2 more
2018Frontiers in Psychiatry12 citations Open access
Semantic Scholar
Association of Variants of Arginine Vasopressin and Arginine Vasopressin Receptor 1A With Severe Acetaminophen Liver Injury
M. Randesi, O. Levran, J. D. da Rosa, Julia D. Hankins +17 more
2017Cellular and Molecular Gastroenterology and Hepatology12 citations Open access
Semantic Scholar

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