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E. Butelman · SciRah

Researcher profile · Semantic Scholar

E. Butelman

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E. Butelman — researcher profile on SciRah

h-index: 44
Works: 149
Citations: 6,547

Most-cited papers

Genetic influences on impulsivity, risk taking, stress responsivity and vulnerability to drug abuse and addiction
M. Kreek, D. A. Nielsen, E. Butelman, K. Laforge
2005Nature Neuroscience1,035 citations
Semantic Scholar
Pharmacotherapy of addictions
M. Kreek, K. Laforge, E. Butelman
2002Nature reviews. Drug discovery358 citations
Semantic Scholar
Opiate addiction and cocaine addiction: underlying molecular neurobiology and genetics.
M. Kreek, O. Levran, Brian Reed, S. Schlussman +2 more
2012Journal of Clinical Investigation207 citations Open access
Semantic Scholar
Effects of the plant-derived hallucinogen salvinorin A on basal dopamine levels in the caudate putamen and in a conditioned place aversion assay in mice: agonist actions at kappa opioid receptors
Yong Zhang, E. Butelman, S. Schlussman, A. Ho +1 more
2005Psychopharmacology187 citations
Semantic Scholar
Kappa opioid receptor/dynorphin system: Genetic and pharmacotherapeutic implications for addiction
E. Butelman, V. Yuferov, M. Kreek
2012Trends in Neurosciences185 citations Open access
Semantic Scholar
Neoclerodane diterpenes as a novel scaffold for mu opioid receptor ligands.
W. Harding, K. Tidgewell, Nathan A. Byrd, H. Cobb +4 more
2005Journal of Medicinal Chemistry147 citations Open access
Semantic Scholar
Effect of the endogenous κ opioid agonist dynorphin A(1–17) on cocaine-evoked increases in striatal dopamine levels and cocaine-induced place preference in C57BL/6J mice
Yong Zhang, E. Butelman, S. Schlussman, A. Ho +1 more
2004Psychopharmacology116 citations
Semantic Scholar
Neuropathic and chronic pain stimuli downregulate central mu-opioid and dopaminergic transmission.
K. Niikura, M. Narita, E. Butelman, M. Kreek +1 more
2010TIPS - Trends in Pharmacological Sciences111 citations
Semantic Scholar
The plant-derived hallucinogen, salvinorin A, produces κ-opioid agonist-like discriminative effects in rhesus monkeys
E. Butelman, T. J. Harris, M. Kreek
2004Psychopharmacology102 citations
Semantic Scholar
Current status of opioid addiction treatment and related preclinical research
M. Kreek, Brian Reed, E. Butelman
2019Science Advances96 citations Open access
Semantic Scholar
Behavioral and Neurochemical Changes Induced by Oxycodone Differ Between Adolescent and Adult Mice
Yong Zhang, R. Picetti, E. Butelman, S. Schlussman +2 more
2008Neuropsychopharmacology82 citations Open access
Semantic Scholar
Overdose mortality rates for opioids and stimulant drugs are substantially higher in men than in women: state-level analysis
E. Butelman, Yue-Feng Huang, D. Epstein, Y. Shaham +3 more
2023Neuropsychopharmacology81 citations Open access
Semantic Scholar
Microarray Studies of Psychostimulant‐Induced Changes in Gene Expression
V. Yuferov, D. A. Nielsen, E. Butelman, M. Kreek
2005Addiction Biology81 citations
Semantic Scholar
Pharmacokinetics of the plant‐derived κ‐opioid hallucinogen salvinorin A in nonhuman primates
Matthew D. Schmidt, M. Schmidt, E. Butelman, W. Harding +4 more
200575 citations
Semantic Scholar
Effect of the endogenous kappa opioid agonist dynorphin A(1-17) on cocaine-evoked increases in striatal dopamine levels and cocaine-induced place preference in C57BL/6J mice.
Yong Zhang, E. Butelman, S. Schlussman, A. Ho +1 more
2004Psychopharmacology69 citations
Semantic Scholar
Salvinorin A, a kappa-opioid receptor agonist hallucinogen: pharmacology and potential template for novel pharmacotherapeutic agents in neuropsychiatric disorders
E. Butelman, M. Kreek
2015Frontiers in Pharmacology68 citations Open access
Semantic Scholar
11C-GR103545, a radiotracer for imaging kappa-opioid receptors in vivo with PET: synthesis and evaluation in baboons.
P. Talbot, R. Narendran, E. Butelman, Yi-Yun Huang +5 more
2005Journal of Nuclear Medicine68 citations
Semantic Scholar
Opiate and Cocaine Addiction: From Bench to Clinic and Back to the Bench
M. Kreek, Yan Zhou, E. Butelman, O. Levran
2009Current opinion in pharmacology (Print)67 citations Open access
Semantic Scholar
Determination of Salvinorin A in body fluids by high performance liquid chromatography-atmospheric pressure chemical ionization.
M. Schmidt, T. Prisinzano, K. Tidgewell, W. Harding +3 more
2005Journal of chromatography. B, Analytical technologies in the biomedical and life sciences67 citations
Semantic Scholar
Nicotine addiction: insights from recent animal studies
A. Mathieu-Kia, S. Kellogg, E. Butelman, M. Kreek
2002Psychopharmacology67 citations
Semantic Scholar
Unconditioned Behavioral Effects of the Powerful κ-Opioid Hallucinogen Salvinorin A in Nonhuman Primates: Fast Onset and Entry into Cerebrospinal Fluid
E. Butelman, T. Prisinzano, H. Deng, Szymon Rus +1 more
2009Journal of Pharmacology and Experimental Therapeutics64 citations Open access
Semantic Scholar
PET Imaging of Leptin Biodistribution and Metabolism in Rodents and Primates
G. Ceccarini, R. Flavell, E. Butelman, Michael Synan +8 more
2009Cell Metabolism63 citations Open access
Semantic Scholar
Repeated Administration of Opra Kappa (LY2456302), a Novel, Short-Acting, Selective KOP-r Antagonist, in Persons with and without Cocaine Dependence
Brian Reed, E. Butelman, Rebecca S Fry, R. Kimani +1 more
2017Neuropsychopharmacology62 citations Open access
Semantic Scholar
Effect of the κ opioid agonist R-84760 on cocaine-induced increases in striatal dopamine levels and cocaine-induced place preference in C57BL/6J mice
Yong Zhang, E. Butelman, S. Schlussman, A. Ho +1 more
2004Psychopharmacology61 citations
Semantic Scholar
Mouse Model of the OPRM1 (A118G) Polymorphism: Differential Heroin Self-Administration Behavior Compared with Wild-Type Mice
Yong Zhang, R. Picetti, E. Butelman, A. Ho +2 more
2015Neuropsychopharmacology59 citations Open access
Semantic Scholar
Effects of Salvinorin A, a κ-Opioid Hallucinogen, on a Neuroendocrine Biomarker Assay in Nonhuman Primates with High κ-Receptor Homology to Humans
E. Butelman, M. Mandau, K. Tidgewell, T. Prisinzano +2 more
2007Journal of Pharmacology and Experimental Therapeutics55 citations Open access
Semantic Scholar
Extended access oxycodone self-administration and neurotransmitter receptor gene expression in the dorsal striatum of adult C57BL/6J mice
Yong Zhang, B. Mayer-Blackwell, S. Schlussman, M. Randesi +4 more
2013Psychopharmacology52 citations Open access
Semantic Scholar
The discriminative effects of the κ-opioid hallucinogen salvinorin A in nonhuman primates: dissociation from classic hallucinogen effects
E. Butelman, Szymon Rus, T. Prisinzano, M. Kreek
2010Psychopharmacology47 citations Open access
Semantic Scholar
Genetics of Opiate Addiction
Brian Reed, E. Butelman, V. Yuferov, M. Randesi +1 more
2014Current Psychiatry Reports46 citations
Semantic Scholar
Effects of the novel relatively short-acting kappa opioid receptor antagonist LY2444296 in behaviors observed after chronic extended-access cocaine self-administration in rats
M. Valenza, E. Butelman, M. Kreek
2017Psychopharmacology45 citations Open access
Semantic Scholar
The plant-derived hallucinogen, salvinorin A, produces kappa-opioid agonist-like discriminative effects in rhesus monkeys.
E. Butelman, T. J. Harris, M. Kreek
2004Psychopharmacology43 citations
Semantic Scholar
Dose preference and dose escalation in extended-access cocaine self-administration in Fischer and Lewis rats
R. Picetti, A. Ho, E. Butelman, M. Kreek
2010Psychopharmacology41 citations Open access
Semantic Scholar
Pharmacokinetics of the plant-derived kappa-opioid hallucinogen salvinorin A in nonhuman primates.
Matthew D. Schmidt, M. Schmidt, E. Butelman, W. Harding +4 more
2005Synapse41 citations
Semantic Scholar
Antiallodynic Effects of Loperamide and Fentanyl against Topical Capsaicin-Induced Allodynia in Unanesthetized Primates
E. Butelman, T. J. Harris, M. Kreek
2004Journal of Pharmacology and Experimental Therapeutics39 citations
Semantic Scholar
Chronic escalating cocaine exposure, abstinence/withdrawal, and chronic re-exposure: Effects on striatal dopamine and opioid systems in C57BL/6J mice
Yong Zhang, S. Schlussman, J. Rabkin, E. Butelman +2 more
2012Neuropharmacology35 citations Open access
Semantic Scholar
Adolescent oxycodone self administration alters subsequent oxycodone-induced conditioned place preference and anti-nociceptive effect in C57BL/6J mice in adulthood
Yong Zhang, Kyle A. Windisch, J. Altschuler, S. Rahm +2 more
2016Neuropharmacology34 citations Open access
Semantic Scholar
Neuroimmune mechanisms of opioid use disorder and recovery: Translatability to human studies, and future research directions
E. Butelman, R. Goldstein, C. Nwaneshiudu, K. Girdhar +3 more
2023Neuroscience33 citations Open access
Semantic Scholar
Impact of Pharmacological Manipulation of the κ-Opioid Receptor System on Self-grooming and Anhedonic-like Behaviors in Male Mice
E. Butelman, Bryan D. McElroy, T. Prisinzano, M. Kreek
2019Journal of Pharmacology and Experimental Therapeutics33 citations Open access
Semantic Scholar
GR89,696: A Potent κ-Opioid Agonist with Subtype Selectivity in Rhesus Monkeys
E. Butelman, M. C. Holden Ko, J. Traynor, Jeffrey A. Vivian +2 more
2001Journal of Pharmacology and Experimental Therapeutics33 citations
Semantic Scholar
Biological clock: Biological clocks may modulate drug addiction
V. Yuferov, E. Butelman, M. Kreek
2005European Journal of Human Genetics32 citations Open access
Semantic Scholar
Effect of the kappa opioid agonist R-84760 on cocaine-induced increases in striatal dopamine levels and cocaine-induced place preference in C57BL/6J mice.
Yong Zhang, E. Butelman, S. Schlussman, A. Ho +1 more
2004Psychopharmacology32 citations
Semantic Scholar
Semisynthetic Neoclerodanes as Kappa Opioid Receptor Probes
K. Lovell, T. Vasiljevik, J. Araya, Anthony Lozama +7 more
2012Bioorganic & Medicinal Chemistry31 citations Open access
Semantic Scholar
Evolving perspectives on neurobiological research on the addictions: celebration of the 30th anniversary of NIDA.
M. Kreek, S. Schlussman, G. Bart, K. Laforge +1 more
2004Neuropharmacology31 citations
Semantic Scholar
Effects of salvinorin A, a kappa-opioid hallucinogen, on a neuroendocrine biomarker assay in nonhuman primates with high kappa-receptor homology to humans.
E. Butelman, M. Mandau, K. Tidgewell, T. Prisinzano +2 more
2007Journal of Pharmacology and Experimental Therapeutics30 citations
Semantic Scholar
Topical Capsaicin-Induced Allodynia in Unanesthetized Primates: Pharmacological Modulation
E. Butelman, Jonathan W. Ball, T. J. Harris, M. Kreek
2003Journal of Pharmacology and Experimental Therapeutics30 citations
Semantic Scholar
SELF ADMINISTRATION OF OXYCODONE BY ADOLESCENT AND ADULT MICE AFFECTS STRIATAL NEUROTRANSMITTER RECEPTOR GENE EXPRESSION
B. Mayer-Blackwell, S. Schlussman, E. Butelman, A. Ho +3 more
2013Neuroscience28 citations Open access
Semantic Scholar
Bidirectional Translational Research: Progress in Understanding Addictive Diseases
M. Kreek, S. Schlussman, Brian Reed, Yong Zhang +4 more
2008Neuropharmacology28 citations Open access
Semantic Scholar
Comparison of the discriminative and neuroendocrine effects of centrally penetrating κ-opioid agonists in rhesus monkeys
E. Butelman, Jonathan W. Ball, M. Kreek
2002Psychopharmacology27 citations
Semantic Scholar
Medications for substance use disorders (SUD): Emerging approaches
E. Butelman, M. Kreek
2017Expert Opinion on Emerging Drugs26 citations Open access
Semantic Scholar
Pharmacological, Pharmacokinetic, and Primate Analgesic Efficacy Profile of the Novel Bradykinin B1 Receptor Antagonist ELN441958
J. Hawkinson, B. Szoke, A. W. Garofalo, D. Hom +17 more
2007Journal of Pharmacology and Experimental Therapeutics26 citations
Semantic Scholar

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