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H. Radomska · SciRah

Researcher profile · Semantic Scholar

H. Radomska

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H. Radomska — researcher profile on SciRah

h-index: 35
Works: 79
Citations: 5,746

Most-cited papers

Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-α (C/EBPα), in acute myeloid leukemia
T. Pabst, B. Mueller, Pu Zhang, H. Radomska +5 more
2001Nature Genetics847 citations
Semantic Scholar
Negative cross-talk between hematopoietic regulators: GATA proteins repress PU.1.
Pu Zhang, G. Behre, Jing Pan, A. Iwama +5 more
1999Proceedings of the National Academy of Sciences of the United States of America507 citations Open access
Semantic Scholar
CCAAT/Enhancer Binding Protein α Is a Regulatory Switch Sufficient for Induction of Granulocytic Development from Bipotential Myeloid Progenitors
H. Radomska, C. Huettner, Pu Zhang, T. Cheng +2 more
1998Molecular and Cellular Biology440 citations Open access
Semantic Scholar
Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-alpha (C/EBPalpha), in acute myeloid leukemia.
T. Pabst, B. Mueller, P. Zhang, H. Radomska +5 more
2001Nature Genetics437 citations
Semantic Scholar
The polymorphism rs944289 predisposes to papillary thyroid carcinoma through a large intergenic noncoding RNA gene of tumor suppressor type
J. Jendrzejewski, Huiling He, H. Radomska, Wei Li +5 more
2012Proceedings of the National Academy of Sciences of the United States of America251 citations Open access
Semantic Scholar
Block of C/EBPα function by phosphorylation in acute myeloid leukemia with FLT3 activating mutations
H. Radomska, D. S. Bassères, R. Zheng, Pu Zhang +13 more
2006Journal of Experimental Medicine234 citations Open access
Semantic Scholar
CCAAT/enhancer binding protein epsilon is preferentially up-regulated during granulocytic differentiation and its functional versatility is determined by alternative use of promoters and differential splicing.
Ryuya Yamanaka, Gun-Do Kim, H. Radomska, J. Lekstrom-Himes +4 more
1997Proceedings of the National Academy of Sciences of the United States of America204 citations Open access
Semantic Scholar
Potential Autoregulation of Transcription Factor PU.1 by an Upstream Regulatory Element
Y. Okuno, Gang Huang, F. Rosenbauer, E. Evans +8 more
2005Molecular and Cellular Biology191 citations Open access
Semantic Scholar
Down regulation of PSA by C/EBPα is associated with loss of AR expression and inhibition of PSA promoter activity in the LNCaP cell Line
Hong Yin, H. Radomska, D. Tenen, J. Glass
2006BMC Cancer179 citations Open access
Semantic Scholar
The dual epigenetic role of PRMT5 in acute myeloid leukemia: gene activation and repression via histone arginine methylation
Somayeh S. Tarighat, R. Santhanam, D. Frankhouser, H. Radomska +13 more
2015Leukemia155 citations Open access
Semantic Scholar
Phosphorylation of C/EBPα Inhibits Granulopoiesis
S. E. Ross, H. Radomska, Bo Wu, Pu Zhang +6 more
2004Molecular and Cellular Biology152 citations Open access
Semantic Scholar
E47 activates the Ig‐heavy chain and TdT loci in non‐B cells.
John K. Choi, Chun-Pyn Shen, H. Radomska, L. Eckhardt +1 more
1996EMBO Journal114 citations
Semantic Scholar
Regulation of the PU.1 gene by distal elements.
Youlin Li, Yutaka Okuno, Pu Zhang, H. Radomska +7 more
2001Blood113 citations
Semantic Scholar
CCAAT/enhancer binding protein alpha is a regulatory switch sufficient for induction of granulocytic development from bipotential myeloid progenitors.
H. Radomska, C. Huettner, P. Zhang, T. Cheng +2 more
1998Molecular and Cellular Biology112 citations
Semantic Scholar
The gene signature in CCAAT-enhancer-binding protein α dysfunctional acute myeloid leukemia predicts responsiveness to histone deacetylase inhibitors
A. Liss, C. Ooi, P. Zjablovskaja, T. Benoukraf +9 more
2014Haematologica105 citations Open access
Semantic Scholar
The amino terminal and E2F interaction domains are critical for C/EBP alpha-mediated induction of granulopoietic development of hematopoietic cells.
F. D'Alo', L. Johansen, E. Nelson, H. Radomska +4 more
2003Blood100 citations Open access
Semantic Scholar
Ras Signaling Enhances the Activity of C/EBPα to Induce Granulocytic Differentiation by Phosphorylation of Serine 248*
G. Behre, S. M. Singh, Huai-Tian Liu, L. T. Bortolin +6 more
2002Journal of Biological Chemistry94 citations Open access
Semantic Scholar
Induction of granulocytic differentiation by 2 pathways.
Pu Zhang, E. Nelson, H. Radomska, Junko Iwasaki-Arai +3 more
2002Blood87 citations
Semantic Scholar
Differential regulation of the human and murine CD34 genes in hematopoietic stem cells
Y. Okuno, H. Iwasaki, C. Huettner, H. Radomska +3 more
2002Proceedings of the National Academy of Sciences of the United States of America85 citations Open access
Semantic Scholar
Pharmacological targeting of miR-155 via the NEDD8-activating enzyme inhibitor MLN4924 (Pevonedistat) in FLT3-ITD acute myeloid leukemia
Jihane Khalife, H. Radomska, R. Santhanam, Xiaomeng Huang +20 more
2015Leukemia80 citations Open access
Semantic Scholar
Phosphorylation of C/EBPalpha inhibits granulopoiesis.
S. E. Ross, H. Radomska, Bo Wu, Pu Zhang +6 more
2004Molecular and Cellular Biology75 citations
Semantic Scholar
PTCSC3 Is Involved in Papillary Thyroid Carcinoma Development by Modulating S100A4 Gene Expression.
J. Jendrzejewski, A. Thomas, S. Liyanarachchi, Andrew Eiterman +7 more
2015Journal of Clinical Endocrinology and Metabolism73 citations Open access
Semantic Scholar
Absence of the transcription factor CCAAT enhancer binding protein alpha results in loss of myeloid identity in bcr/abl-induced malignancy.
Katharina Wagner, Pu Zhang, F. Rosenbauer, B. Drescher +6 more
2006Proceedings of the National Academy of Sciences of the United States of America70 citations
Semantic Scholar
Downregulation of c-Jun Expression by Transcription Factor C/EBPα Is Critical for Granulocytic Lineage Commitment
J. Rangatia, R. Vangala, N. Treiber, Pu Zhang +4 more
2002Molecular and Cellular Biology69 citations Open access
Semantic Scholar
Octamer Binding Factors and Their Coactivator Can Activate the Murine PU.1 (spi-1) Promoter*
Hui-Min Chen, Pu Zhang, H. Radomska, C. Hetherington +2 more
1996Journal of Biological Chemistry67 citations Open access
Semantic Scholar
Targeting CDK1 promotes FLT3-activated acute myeloid leukemia differentiation through C/EBPα.
H. Radomska, M. Alberich-Jorda, B. Will, David A. Gonzalez +2 more
2012Journal of Clinical Investigation62 citations Open access
Semantic Scholar
Inducible expression of BCR/ABL using human CD34 regulatory elements results in a megakaryocytic myeloproliferative syndrome.
C. Huettner, S. Koschmieder, H. Iwasaki, Junko Iwasaki-Arai +3 more
2003Blood62 citations Open access
Semantic Scholar
Lenalidomide-mediated enhanced translation of C/EBPα-p30 protein up-regulates expression of the antileukemic microRNA-181a in acute myeloid leukemia.
Christopher J. Hickey, S. Schwind, H. Radomska, A. Dorrance +23 more
2013Blood59 citations Open access
Semantic Scholar
C/EBPα and DEK coordinately regulate myeloid differentiation.
R. Koleva, Scott B. Ficarro, H. Radomska, M. Carrasco-Alfonso +6 more
2012Blood58 citations Open access
Semantic Scholar
CDDO induces granulocytic differentiation of myeloid leukemic blasts through translational up-regulation of p42 CCAAT enhancer binding protein alpha.
S. Koschmieder, F. D'Alo', H. Radomska, Christine Schöneich +18 more
2007Blood58 citations Open access
Semantic Scholar
C/EBPγ deregulation results in differentiation arrest in acute myeloid leukemia.
M. Alberich-Jorda, Bas J. Wouters, M. Balastik, Clara Shapiro-Koss +14 more
2012Journal of Clinical Investigation55 citations Open access
Semantic Scholar
Transgenic targeting with regulatory elements of the human CD34 gene.
H. Radomska, David A. Gonzalez, Yutaka Okuno, Hiromi Iwasaki +4 more
2002Blood54 citations
Semantic Scholar
Distal elements are critical for human CD34 expression in vivo.
Y. Okuno, C. Huettner, H. Radomska, V. Petkova +3 more
2002Blood45 citations
Semantic Scholar
A nuclear factor Y (NFY) site positively regulates the human CD34 stem cell gene.
H. Radomska, A. B. Satterthwaite, N. Taranenko, S. Narravula +2 more
1999Blood39 citations
Semantic Scholar
RUNX1 regulates the CD34 gene in haematopoietic stem cells by mediating interactions with a distal regulatory element
E. Levantini, Sanghoon Lee, H. Radomska, C. Hetherington +15 more
2011EMBO Journal35 citations Open access
Semantic Scholar
Constitutively expressed Oct-2 prevents immunoglobulin gene silencing in myeloma x T cell hybrids.
H. Radomska, Chun-Pyn Shen, T. Kadesch, L. Eckhardt
1994Immunity35 citations Open access
Semantic Scholar
C/EBPα Is Required for Proteolytic Cleavage of Cyclin A by Calpain 3 in Myeloid Precursor Cells*
A. Welm, N. Timchenko, Y. Ono, H. Sorimachi +4 more
2002Journal of Biological Chemistry32 citations Open access
Semantic Scholar
Expression of the homeo box gene family in Drosophila.
Michael S. Levine, K. Harding, C. Wedeen, Helen J. Doyle +2 more
1985Cold Spring Harbor Symposia on Quantitative Biology31 citations
Semantic Scholar
Decitabine and vitamin D3 differentially affect hematopoietic transcription factors to induce monocytic differentiation.
S. Koschmieder, Shuchi Agrawal, H. Radomska, C. Huettner +5 more
2007International Journal of Oncology29 citations
Semantic Scholar
Dominant-Interfering C/ebpα Stimulates Primitive Erythropoiesis in Zebrafish
Tingxi Liu, Jennifer Rhodes, M. Deng, Karl Hsu +4 more
200727 citations Open access
Semantic Scholar
Multiple control elements are required for expression of the human CD34 gene.
H. Radomska, A. Satterthwaite, T. C. Burn, I. Oliff +2 more
1998Gene27 citations
Semantic Scholar
Structure-Activity Relationship of para-Carborane Selective Estrogen Receptor β Agonists.
David Sedlák, Tyler A. Wilson, W. Tjarks, H. Radomska +13 more
2021Journal of Medicinal Chemistry24 citations Open access
Semantic Scholar
ZNF143 protein is an important regulator of the myeloid transcription factor C/EBPα
David A. Gonzalez, A. Luyten, Boris A. Bartholdy, Qi-Ling Zhou +16 more
2017Journal of Biological Chemistry23 citations Open access
Semantic Scholar
Mammalian cell fusion in an electroporation device.
H. Radomska, L. Eckhardt
1995JIM - Journal of Immunological Methods22 citations Open access
Semantic Scholar
Activity of Estrogen Receptor β Agonists in Therapy-Resistant Estrogen Receptor-Positive Breast Cancer
Jharna Datta, Natalie Willingham, Jasmine M. Manouchehri, P. Schnell +13 more
2022bioRxiv21 citations Open access
Semantic Scholar
The amino terminal and E2F interaction domains are critical for C/EBPα-mediated induction of granulopoietic development of hematopoietic cells Running Head: C/EBPα mediated granulopoietic development Scientific Section Heading: Hematopoiesis
D. Tenen, L. Johansen, F. D'Alo', E. Nelson +4 more
200318 citations
Semantic Scholar
Two promoters direct expression of the murine Spi-B gene, an Ets family transcription factor.
Hui-Min Chen, David A. Gonzalez, H. Radomska, M. Voso +4 more
1998Gene16 citations
Semantic Scholar
Dominant-interfering C/EBPalpha stimulates primitive erythropoiesis in zebrafish.
Tingxi Liu, Jennifer Rhodes, M. Deng, Karl Hsu +4 more
2007Experimental Hematology15 citations
Semantic Scholar
A Cell-Based High-Throughput Screening for Inducers of Myeloid Differentiation
H. Radomska, F. Jernigan, Sohei Nakayama, S. E. Jorge +3 more
2015Journal of biomolecular screening13 citations Open access
Semantic Scholar
Unique Function for Carboxyl-Terminal Domain of Oct-2 in Ig-Secreting Cells1
M. Sharif, H. Radomska, David M. Miller, L. Eckhardt
2001Journal of Immunology13 citations Open access
Semantic Scholar

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D. Tenen×32
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D. Tenen — researcher profile on SciRah
Pu Zhang×15
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C. Huettner×8
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C. Huettner — researcher profile on SciRah
David A. Gonzalez×6
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