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N. Proost · SciRah

Researcher profile · Semantic Scholar

N. Proost

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N. Proost — researcher profile on SciRah

h-index: 15
Works: 28
Citations: 2,072

Most-cited papers

Cell of origin of small cell lung cancer: inactivation of Trp53 and Rb1 in distinct cell types of adult mouse lung.
K. Sutherland, N. Proost, I. Brouns, D. Adriaensen +2 more
2011Cancer Cell508 citations Open access
Semantic Scholar
A functional role for tumor cell heterogeneity in a mouse model of small cell lung cancer.
J. Calbó, E. van Montfort, N. Proost, E. van Drunen +3 more
2011Cancer Cell377 citations Open access
Semantic Scholar
Multiple cells-of-origin of mutant K-Ras–induced mouse lung adenocarcinoma
K. Sutherland, Ji-Ying Song, Min-chul Kwon, N. Proost +2 more
2014Proceedings of the National Academy of Sciences of the United States of America246 citations Open access
Semantic Scholar
SOX2 Is the Determining Oncogenic Switch in Promoting Lung Squamous Cell Carcinoma from Different Cells of Origin
G. Ferone, Ji-Ying Song, K. Sutherland, R. Bhaskaran +5 more
2016Cancer Cell212 citations Open access
Semantic Scholar
Transcription Factor NFIB Is a Driver of Small Cell Lung Cancer Progression in Mice and Marks Metastatic Disease in Patients
Ekaterina A. Semenova, Min-chul Kwon, K. Monkhorst, Ji-Ying Song +16 more
2016Cell Reports137 citations Open access
Semantic Scholar
Polycomb Repressive Complex 2 Is a Barrier to KRAS-Driven Inflammation and Epithelial-Mesenchymal Transition in Non-Small-Cell Lung Cancer.
M. Serresi, G. Gargiulo, N. Proost, Bjørn Siteur +9 more
2016Cancer Cell117 citations Open access
Semantic Scholar
Deleted in colorectal carcinoma suppresses metastasis in p53-deficient mammary tumours
P. Krimpenfort, Ji-Ying Song, N. Proost, John Zevenhoven +2 more
2012Nature96 citations
Semantic Scholar
Rapid target gene validation in complex cancer mouse models using re-derived embryonic stem cells
I. Huijbers, R. Bin Ali, C. Pritchard, M. Cozijnsen +10 more
2014EMBO Molecular Medicine90 citations Open access
Semantic Scholar
Paracrine signaling between tumor subclones of mouse SCLC: a critical role of ETS transcription factor Pea3 in facilitating metastasis
Min-chul Kwon, N. Proost, Ji-Ying Song, K. Sutherland +2 more
2015Genes & Development74 citations Open access
Semantic Scholar
Radiosensitivity is an acquired vulnerability of PARPi-resistant BRCA1-deficient tumors
M. Barazas, A. Gasparini, Yike Huang, Asli Küçükosmanoglu +10 more
2018bioRxiv48 citations Open access
Semantic Scholar
Frat oncoproteins act at the crossroad of canonical and noncanonical Wnt-signaling pathways
R. van Amerongen, M. Nawijn, J. Lambooij, N. Proost +2 more
2010Oncogene43 citations
Semantic Scholar
Ezh2 inhibition in Kras-driven lung cancer amplifies inflammation and associated vulnerabilities
M. Serresi, Bjørn Siteur, Danielle Hulsman, Carlos Company +8 more
2018Journal of Experimental Medicine37 citations Open access
Semantic Scholar
Immune response in lung cancer mouse model mimics human anti-Hu reactivity
Meleeneh Kazarian, J. Calbó, N. Proost, C. Carpenter +2 more
2009Journal of Neuroimmunology24 citations Open access
Semantic Scholar
Frat2 mediates the oncogenic activation of Rac by MLL fusions.
V. Walf-Vorderwülbecke, J. de Boer, S. Horton, R. van Amerongen +3 more
2012Blood22 citations
Semantic Scholar
QPCTL regulates macrophage and monocyte abundance and inflammatory signatures in the tumor microenvironment
Kaspar Bresser, M. Logtenberg, M. Toebes, N. Proost +5 more
2022Oncoimmunology15 citations Open access
Semantic Scholar
Combined inhibition of EZH2 and ATM is synthetic lethal in BRCA1-deficient breast cancer
L. Ratz, Chiara S. Brambillasca, L. Bartke, Maxim A. Huetzen +18 more
2022Breast Cancer Research13 citations Open access
Semantic Scholar
Histone methyltransferase DOT1L maintains cell state and restricts cytotoxic potential of CD8 T cells
Muddassir Malik, W. de Leeuw, M. A. Aslam, E. M. Kwesi-Maliepaard +12 more
2025Science Advances4 citations Open access
Semantic Scholar
Large-Scale Characterization of Orthotopic Cell Line-Derived Xenografts Identifies TGF-β Signaling as a Key Regulator of Breast Cancer Morphology and Aggressiveness.
C. Lutz, Xue Chao, Bim de Klein, J. Bhin +12 more
2025Cancer Research4 citations Open access
Semantic Scholar
C-terminal Truncation and Fusion Partner Determine Oncogenicity of FGFR3.
Julia Yemelyanenko, J. Bhin, E. van der Burg, Anne Paulien Drenth +17 more
2025Cancer Research2 citations
Semantic Scholar
Abstract LB-201: Functional role for tumor heterogeneity: Paracrine signaling between tumor subclones of mouse SCLC promotes metastasis
Min-chul Kwon, N. Proost, K. Sutherland, John Zevenhoven +1 more
20151 citations
Semantic Scholar
Abstract 5100: Secretome proteomics to identify indicators for lung cancer treatment response prediction and monitoring
Tieneke B. M. Schaaij-Visser, N. Proost, Remco Nagel, S. Piersma +4 more
20111 citations
Semantic Scholar
6 Mouse models for lung cancer and mesothelioma
A. Berns, J. Calbo-Angrill, K. Sutherland, E. van Montfort +1 more
20101 citations
Semantic Scholar
Abstract 6624: MYC promotes lobuloalveologenesis and mammary tumorigenesis in male mice
Emilia M. Pulver, E. van der Burg, Anne Paulien Drenth, Julia Yemelyanenko +10 more
2024Cancer Research0 citations
Semantic Scholar
Abstract IA05: Polycomb repressive complex-2 is a barrier to Kras-driven inflammation and epithelial-mesenchymal transition in non-small cell lung cancer
M. Serresi, G. Gargiulo, N. Proost, Bjørn Siteur +9 more
20160 citations
Semantic Scholar
Abstract LB-204: Neoadjuvant Ezh2 inhibition amplifies an inflammatory program and sensitizes Kras-driven NSCLC to anti-NF-κB inhibition
M. Serresi, Bjørn Siteur, M. Cesaroni, N. Proost +3 more
20160 citations
Semantic Scholar
L11.05 RAPID VALIDATION OF CANCER GENES AND DRUG TARGETS IN GENETICALLY ENGINEERED MOUSE MODELS OF CANCER
I. Huijbers, R. Bin Ali, C. Pritchard, M. Cozijnsen +6 more
20130 citations Open access
Semantic Scholar
Abstract SY10-02: Mouse models for (non) small cell lung cancer: Heterogeneity and cell of origin
A. Berns, K. Sutherland, Min-chul Kwon, N. Proost +1 more
20120 citations
Semantic Scholar
Symposium Engineering influences in cancer research
Kate D. Sutherland, J. Calbó, Minju Kwon, N. Proost +1 more
0 citations
Semantic Scholar

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