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J. Ungerstedt · SciRah

Researcher profile · Semantic Scholar

J. Ungerstedt

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J. Ungerstedt — researcher profile on SciRah

h-index: 23
Works: 78
Citations: 1,992

Most-cited papers

Role of thioredoxin in the response of normal and transformed cells to histone deacetylase inhibitors.
J. Ungerstedt, Y. Sowa, Weisheng Xu, Y. Shao +6 more
2005Proceedings of the National Academy of Sciences of the United States of America534 citations Open access
Semantic Scholar
Nicotinamide is a potent inhibitor of proinflammatory cytokines
J. Ungerstedt, M. Blombäck, T. Söderström
2003Clinical and Experimental Immunology227 citations Open access
Semantic Scholar
Motexafin Gadolinium, a Tumor-selective Drug Targeting Thioredoxin Reductase and Ribonucleotide Reductase*
S. I. Hashemy, J. Ungerstedt, Farnaz Zahedi Avval, A. Holmgren
2006Journal of Biological Chemistry159 citations Open access
Semantic Scholar
Hemorrhagic symptoms and bleeding risk in obligatory carriers of type 3 von Willebrand disease: an international, multicenter study
G. Castaman, F. Rodeghiero, A. Tosetto, A. Cappelletti +10 more
2006Journal of Thrombosis and Haemostasis73 citations Open access
Semantic Scholar
Genome-wide profiling of histone H3 lysine 27 and lysine 4 trimethylation in multiple myeloma reveals the importance of Polycomb gene targeting and highlights EZH2 as a potential therapeutic target
P. Agarwal, M. Alzrigat, Alba Atienza Párraga, S. Enroth +10 more
2016OncoTarget64 citations Open access
Semantic Scholar
Avapritinib versus Placebo in Indolent Systemic Mastocytosis.
J. Gotlib, M. Castells, H. Elberink, F. Siebenhaar +49 more
2023NEJM Evidence62 citations Open access
Semantic Scholar
Comprehensive mapping of the effects of azacitidine on DNA methylation, repressive/permissive histone marks and gene expression in primary cells from patients with MDS and MDS-related disease
M. Tobiasson, Hani Abdulkadir, A. Lennartsson, S. Katayama +14 more
2017OncoTarget58 citations Open access
Semantic Scholar
Activation of a Subset of Evolutionarily Young Transposable Elements and Innate Immunity are Linked to Clinical Responses to 5-Azacytidine
Hitoshi Ohtani, A. Ørskov, A. S. Helbo, L. Gillberg +8 more
2020Cancer Research50 citations Open access
Semantic Scholar
KIT signaling is dispensable for human mast cell progenitor development.
J. Dahlin, M. Ekoff, J. Grootens, Liza Löf +5 more
2017Blood50 citations Open access
Semantic Scholar
Deciphering the differentiation trajectory from hematopoietic stem cells to mast cells.
J. Grootens, J. Ungerstedt, G. Nilsson, J. Dahlin
2018Blood Advances47 citations Open access
Semantic Scholar
Outcomes of patients with chronic myelomonocytic leukaemia treated with non-curative therapies: a retrospective cohort study.
L. Pleyer, M. Leisch, A. Kourakli, E. Padron +37 more
2021The Lancet Haematology46 citations
Semantic Scholar
In vivo redox state of human thioredoxin and redox shift by the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA).
J. Ungerstedt, Yatao Du, Huihui Zhang, Deepika Nair +1 more
2012Free Radical Biology & Medicine39 citations
Semantic Scholar
Mutations in histone modulators are associated with prolonged survival during azacitidine therapy
M. Tobiasson, D. Mclornan, M. Karimi, M. Dimitriou +11 more
2015OncoTarget38 citations Open access
Semantic Scholar
Critical role of Lama4 for hematopoiesis regeneration and acute myeloid leukemia progression
H. Cai, M. Kondo, L. Sandhow, P. Xiao +8 more
2021Blood32 citations Open access
Semantic Scholar
Clinical Outcomes of Adults with Systemic Mastocytosis: A 15-Year Multidisciplinary Experience
J. Ungerstedt, Christopher Ljung, Monika Klimkowska, Theo Gülen
2022Cancers31 citations Open access
Semantic Scholar
Single-cell analysis reveals the KIT D816V mutation in haematopoietic stem and progenitor cells in systemic mastocytosis
J. Grootens, J. Ungerstedt, M. Ekoff, E. Rönnberg +7 more
2018bioRxiv29 citations Open access
Semantic Scholar
Clotting Onset Time May Be a Predictor of Outcome in Human Brain Injury: A Pilot Study
J. Ungerstedt, A. Grenander, S. Bredbacka, M. Blombäck
2003Journal of Neurosurgical Anesthesiology29 citations
Semantic Scholar
Co-mutation pattern, clonal hierarchy, and clone size concur to determine disease phenotype of SRSF2P95-mutated neoplasms
G. Todisco, M. Creignou, A. Gallì, P. Guglielmelli +18 more
2020Leukemia28 citations
Semantic Scholar
Autologous hematopoietic stem cell transplantation in multiple myeloma and lymphoma: an analysis of factors influencing stem cell collection and hematological recovery
J. Ungerstedt, E. Watz, K. Uttervall, B. Johansson +6 more
2012Medical Oncology28 citations
Semantic Scholar
Epigenetic Modifiers in Myeloid Malignancies: The Role of Histone Deacetylase Inhibitors
J. Ungerstedt
2018International Journal of Molecular Sciences27 citations Open access
Semantic Scholar
Glutaredoxin mediated redox effects of coenzyme Q10 treatment in type 1 and type 2 diabetes patients
Sergio J. Montano, J. Grunler, Deepika Nair, M. Tekle +5 more
2015BBA Clinical27 citations Open access
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Plasma glutaredoxin activity in healthy subjects and patients with abnormal glucose levels or overt type 2 diabetes
Yatao Du, Huihui Zhang, Sergio J. Montano, Jesper Hegestam +4 more
2014Acta Diabetologica26 citations
Semantic Scholar
Single-cell transcriptomics reveals the identity and regulators of human mast cell progenitors
Chenyan Wu, Daryl Boey, Oscar Bril, J. Grootens +7 more
2021bioRxiv25 citations Open access
Semantic Scholar
Discrepancy between antithrombin activity methods revealed in Antithrombin Stockholm: do factor Xa-based methods overestimate antithrombin activity in some patients?
J. Ungerstedt, S. Schulman, N. Egberg, J. Antovic +1 more
2002Blood22 citations Open access
Semantic Scholar
Methylseleninic Acid Sensitizes Ovarian Cancer Cells to T-Cell Mediated Killing by Decreasing PDL1 and VEGF Levels
Deepika Nair, E. Rådestad, P. Khalkar, N. Díaz-Argelich +5 more
2018Frontiers in Oncology21 citations Open access
Semantic Scholar
Nicotinamide inhibits endotoxin‐induced monocyte tissue factor expression
J. Ungerstedt, K. Heimersson, T. Söderström, M. Hansson
2003Journal of Thrombosis and Haemostasis21 citations Open access
Semantic Scholar
Characterization of the bone marrow niche in patients with chronic myeloid leukemia identifies CXCL14 as a new therapeutic option
M. Dolinska, H. Cai, A. Månsson, Jingyi Shen +25 more
2023Blood19 citations Open access
Semantic Scholar
CD203c distinguishes the erythroid and mast cell‐basophil differentiation trajectories among human FcεRI+ bone marrow progenitors
J. Grootens, J. Ungerstedt, Chen-Yan Wu, Kerstin Hamberg Levedahl +2 more
2019Allergy. European Journal of Allergy and Clinical Immunology19 citations Open access
Semantic Scholar
Azacitidine induces profound genome-wide hypomethylation in primary myelodysplastic bone marrow cultures but may also reduce histone acetylation
M. Grövdal, M. Karimi, M. Tobiasson, Lovisa E. Reinius +6 more
2014Leukemia18 citations
Semantic Scholar
Histone deacetylase inhibitor SAHA mediates mast cell death and epigenetic silencing of constitutively active D816V KIT in systemic mastocytosis
K. Lyberg, H. Ali, J. Grootens, Matilda Kjellander +5 more
2016OncoTarget17 citations Open access
Semantic Scholar
Selenite and methylseleninic acid epigenetically affects distinct gene sets in myeloid leukemia: A genome wide epigenetic analysis
P. Khalkar, H. Ali, Paula L Codo, Nuria Díaz Argelich +6 more
2018Free Radical Biology & Medicine15 citations Open access
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Allogeneic hematopoietic stem cell transplantation for chronic myelomonocytic leukemia: Clinical and molecular genetic prognostic factors in a Nordic population.
E. Wedge, J. W. Hansen, I. Dybedal, M. Creignou +17 more
2021Transplantation and Cellular Therapy13 citations Open access
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A proteomic and transcriptomic screening demonstrate increased mast cell-derived CCL23 in systemic mastocytosis.
S. Söderlund, Daryl Boey, Wouter van Midden, Matilda Kjellander +4 more
2023Journal of Allergy and Clinical Immunology12 citations
Semantic Scholar
Localization-Specific Expression of CCR1 and CCR5 by Mast Cell Progenitors
M. Salomonsson, J. Dahlin, J. Ungerstedt, J. Hallgren
2020Frontiers in Immunology11 citations Open access
Semantic Scholar
Prognostic scoring systems and comorbidities in chronic myelomonocytic leukaemia: a nationwide population‐based study
Daniel Moreno Berggren, Matilda Kjellander, Ellen Backlund, M. Engvall +9 more
2020British Journal of Haematology9 citations Open access
Semantic Scholar
Serum Glutaredoxin Activity as a Marker of Oxidative Stress in Chronic Kidney Disease: A Pilot Study
A. Levin, Deepika Nair, A. Qureshi, P. Bárány +5 more
2018Nephron9 citations
Semantic Scholar
Detection of circulating mast cells in advanced systemic mastocytosis
J. Dahlin, J. Ungerstedt, J. Grootens, B. Sander +3 more
2016Leukemia9 citations
Semantic Scholar
Demonstration of human mast cell progenitors in the bone marrow
M. Salomonsson, J. Ungerstedt, P. A. Alvarado-Vázquez, J. Hallgren
2019Allergy. European Journal of Allergy and Clinical Immunology6 citations Open access
Semantic Scholar
Bedside monitoring of coagulation activation after challenging healthy volunteers with intravenous endotoxin.
J. Ungerstedt, A. Soop, A. Sollevi, M. Blombäck
2003Thrombosis Research6 citations
Semantic Scholar
Validation of Guidelines for Genetic Investigation of Myeloid Neoplasms with Germline Predisposition: Results from a Prospective Cohort Study
B. Tesi, Anna Robelius, Berivan Baskin, V. Lazarevic +25 more
2025Clinical Cancer Research5 citations Open access
Semantic Scholar
Different impact of intermediate and unfavourable cytogenetics at the time of diagnosis on outcome of de novo AML after allo-SCT: a long-term retrospective analysis from a single institution
H. Nahi, M. Remberger, M. Machaczka, J. Ungerstedt +5 more
2012Medical Oncology5 citations
Semantic Scholar
Avapritinib improves cutaneous involvement in patients with indolent systemic mastocytosis: Results from the randomized, phase 2, interventional PIONEER study.
F. Siebenhaar, S. Broesby-Olsen, M. Castells, T. George +27 more
2026Journal of American Academy of Dermatology4 citations Open access
Semantic Scholar
Effects of the Therapeutic Armamentarium on Survival and Time to Next Treatment in CMML Subtypes: An International Analysis of 950 Cases Coordinated By the AGMT Study Group
L. Pleyer, M. Leisch, A. Kourakli, E. Padron +35 more
2019Blood4 citations Open access
Semantic Scholar
Omalizumab alleviates pruritus in myeloproliferative neoplasms
Anna Ravn Landtblom, J. Ungerstedt, A. Hedlund, M. Tobiasson +2 more
2023Haematologica3 citations Open access
Semantic Scholar
Histone Deacetylase Inhibitor SAHA Mediates Epigenetic Silencing of KIT D816V Mutated Systemic Mastocytosis Primary Mast Cells and Selective Apoptosis of Mutated Mast Cells
Hani Abdulkadir, J. Grootens, Matilda Kjellander, E. Lindberg +2 more
20153 citations
Semantic Scholar
Comorbidities and mutations including single‐ and multihit TET2 mutations in relation to outcome in chronic myelomonocytic leukaemia—A population‐based study
M. K. Kynning, E. Westerberg, Linda Forsell, M. Creignou +11 more
2025British Journal of Haematology2 citations Open access
Semantic Scholar
No indication of aberrant neutrophil extracellular trap release in indolent or advanced systemic mastocytosis
A. Rosell, C. Karlström, J. Dahlin, Daryl Boey +4 more
2023Scandinavian Journal of Immunology2 citations Open access
Semantic Scholar
P1017: REDUCTIONS IN INDOLENT SYSTEMIC MASTOCYTOSIS BIOMARKER BURDEN WITH AVAPRITINIB IN THE REGISTRATIONAL, DOUBLE-BLIND PLACEBO-CONTROLLED PIONEER TRIAL
J. Gotlib, M. Castells, H. Oude Elberink, F. Siebenhaar +37 more
2023HemaSphere2 citations Open access
Semantic Scholar
[Two cases of VEXAS syndrome].
K. Gunnarsson, Nancy Vivar Pomiano, B. Tesi, M. Tobiasson +2 more
2022Läkartidningen2 citations
Semantic Scholar
Living with systemic mastocytosis: Balancing between vulnerability and resilience: A qualitative study.
K. Levedahl, A. Nilsson, J. Ungerstedt, Mariann Hedström
2022European Journal of Oncology Nursing2 citations Open access
Semantic Scholar

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