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L. Pleyer · SciRah

Researcher profile · Semantic Scholar

L. Pleyer

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L. Pleyer — researcher profile on SciRah

h-index: 26
Works: 131
Citations: 2,049

Most-cited papers

Proposed diagnostic criteria for classical chronic myelomonocytic leukemia (CMML), CMML variants and pre-CMML conditions
P. Valent, A. Orazi, M. Savona, M. Patnaik +26 more
2019Haematologica130 citations Open access
Semantic Scholar
Azacitidine in 302 patients with WHO-defined acute myeloid leukemia: results from the Austrian Azacitidine Registry of the AGMT-Study Group
L. Pleyer, S. Burgstaller, M. Girschikofsky, W. Linkesch +16 more
2014Annals of Hematology100 citations Open access
Semantic Scholar
The double-edged sword of (re)expression of genes by hypomethylating agents: from viral mimicry to exploitation as priming agents for targeted immune checkpoint modulation
F. Wolff, M. Leisch, R. Greil, A. Risch +1 more
2017Cell Communication and Signaling81 citations Open access
Semantic Scholar
Digging deep into “dirty” drugs – modulation of the methylation machinery
L. Pleyer, R. Greil
2015Drug metabolism reviews (Softcover ed.)77 citations Open access
Semantic Scholar
Next Generation Sequencing in AML—On the Way to Becoming a New Standard for Treatment Initiation and/or Modulation?
M. Leisch, Bettina Jansko, N. Zaborsky, R. Greil +1 more
2019Cancers69 citations Open access
Semantic Scholar
Azacitidine in CMML: matched-pair analyses of daily-life patients reveal modest effects on clinical course and survival.
L. Pleyer, U. Germing, W. Sperr, W. Linkesch +16 more
2014Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis69 citations Open access
Semantic Scholar
TIGIT expressing CD4+T cells represent a tumor-supportive T cell subset in chronic lymphocytic leukemia
Kemal Catakovic, F. Gassner, C. Ratswohl, N. Zaborsky +9 more
2017Oncoimmunology68 citations Open access
Semantic Scholar
Azacitidine in patients with WHO-defined AML – Results of 155 patients from the Austrian Azacitidine Registry of the AGMT-Study Group
L. Pleyer, R. Stauder, S. Burgstaller, M. Schreder +14 more
2013Journal of Hematology & Oncology66 citations Open access
Semantic Scholar
Time to repeal and replace response criteria for acute myeloid leukemia?
C. Bloomfield, E. Estey, L. Pleyer, A. Schuh +3 more
2018Blood reviews59 citations Open access
Semantic Scholar
Azacitidine frontline therapy for unfit acute myeloid leukemia patients: clinical use and outcome prediction.
F. Ramos, S. Thepot, L. Pleyer, L. Maurillo +15 more
2015Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis56 citations
Semantic Scholar
Azacitidine in adult patients with acute myeloid leukemia.
A. Schuh, H. Döhner, L. Pleyer, J. Seymour +2 more
2017Critical reviews in oncology/hematology55 citations
Semantic Scholar
Mesenchymal Stem and Progenitor Cells in Normal and Dysplastic Hematopoiesis—Masters of Survival and Clonality?
L. Pleyer, P. Valent, R. Greil
2016International Journal of Molecular Sciences54 citations Open access
Semantic Scholar
Azacitidine for Front-Line Therapy of Patients with AML: Reproducible Efficacy Established by Direct Comparison of International Phase 3 Trial Data with Registry Data from the Austrian Azacitidine Registry of the AGMT Study Group
L. Pleyer, H. Döhner, H. Dombret, J. Seymour +23 more
2017International Journal of Molecular Sciences53 citations Open access
Semantic Scholar
Outcomes of patients with chronic myelomonocytic leukaemia treated with non-curative therapies: a retrospective cohort study.
L. Pleyer, M. Leisch, A. Kourakli, E. Padron +37 more
2021The Lancet Haematology46 citations
Semantic Scholar
Rituximab maintenance versus observation alone in patients with chronic lymphocytic leukaemia who respond to first-line or second-line rituximab-containing chemoimmunotherapy: final results of the AGMT CLL-8a Mabtenance randomised trial.
R. Greil, P. Obrtlíková, L. Smolej, T. Kozák +31 more
2016The Lancet Haematology45 citations
Semantic Scholar
CD44 engagement enhances acute myeloid leukemia cell adhesion to the bone marrow microenvironment by increasing VLA-4 avidity
J. Gutjahr, Elisabeth Bayer, Xiao-Bin Yu, Julia M. Laufer +21 more
2020Haematologica42 citations Open access
Semantic Scholar
Azacitidine front-line in 339 patients with myelodysplastic syndromes and acute myeloid leukaemia: comparison of French-American-British and World Health Organization classifications
L. Pleyer, S. Burgstaller, R. Stauder, M. Girschikofsky +18 more
2016Journal of Hematology & Oncology37 citations Open access
Semantic Scholar
Reactivation of dormant anti-tumor immunity – a clinical perspective of therapeutic immune checkpoint modulation
R. Greil, Evelyn Hutterer, T. Hartmann, L. Pleyer
2017Cell Communication and Signaling35 citations Open access
Semantic Scholar
Clinical Outcomes of 217 Patients with Acute Erythroleukemia According to Treatment Type and Line: A Retrospective Multinational Study
A. Almeida, T. Prebet, R. Itzykson, F. Ramos +30 more
2017International Journal of Molecular Sciences32 citations Open access
Semantic Scholar
Clonal evolution and heterogeneity in metastatic head and neck cancer-An analysis of the Austrian Study Group of Medical Tumour Therapy study group.
T. Melchardt, T. Magnes, C. Hufnagl, A. Thorner +13 more
2018European Journal of Cancer31 citations
Semantic Scholar
Supervised versus autonomous exercise training in breast cancer patients: A multicenter randomized clinical trial
T. Westphal, G. Rinnerthaler, S. Gampenrieder, J. Niebauer +10 more
2018Cancer Medicine30 citations Open access
Semantic Scholar
Evaluation of induction chemotherapies after hypomethylating agent failure in myelodysplastic syndromes and acute myeloid leukemia.
B. Ball, R. Komrokji, L. Adès, M. Sekeres +10 more
2018Blood Advances28 citations Open access
Semantic Scholar
Durable remissions with venetoclax monotherapy in secondary AML refractory to hypomethylating agents and high expression of BCL‐2 and/or BIM
F. Huemer, T. Melchardt, Bettina Jansko, A. Wahida +10 more
2019European Journal of Haematology27 citations Open access
Semantic Scholar
Clinical-genomic profiling of MDS to inform allo-HSCT:Recommendations from an international panel on behalf of the EBMT.
C. Gurnari, M. Robin, L. Adès, M. Aljurf +41 more
2025Blood25 citations Open access
Semantic Scholar
Management of adult patients with CMML undergoing allo-HCT: recommendations from the EBMT PH&G Committee.
Francesco Onida, N. Gagelmann, Y. Chalandon, G. Kobbe +15 more
2024Blood24 citations Open access
Semantic Scholar
Real life experience with frontline azacitidine in a large series of older adults with acute myeloid leukemia stratified by MRC/LRF score: results from the expanded international E-ALMA series (E-ALMA+)
J. Falantes, L. Pleyer, S. Thepot, A. Almeida +19 more
2018Leukemia and Lymphoma24 citations
Semantic Scholar
Myeloid NGS Analyses of Paired Samples from Bone Marrow and Peripheral Blood Yield Concordant Results: A Prospective Cohort Analysis of the AGMT Study Group
Bettina Jansko-Gadermeir, M. Leisch, F. Gassner, N. Zaborsky +9 more
2023Cancers19 citations Open access
Semantic Scholar
The ABNL-MARRO 001 study: a phase 1–2 study of randomly allocated active myeloid target compound combinations in MDS/MPN overlap syndromes
T. Moyo, Jason H. Mendler, R. Itzykson, A. Kishtagari +32 more
2022BMC Cancer19 citations Open access
Semantic Scholar
Sidedness and TP53 mutations impact OS in anti-EGFR but not anti-VEGF treated mCRC - an analysis of the KRAS registry of the AGMT (Arbeitsgemeinschaft Medikamentöse Tumortherapie)
F. Huemer, J. Thaler, G. Piringer, H. Hackl +4 more
2018BMC Cancer19 citations Open access
Semantic Scholar
Functionally distinct promoter classes initiate transcription via different mechanisms reflected in focused versus dispersed initiation patterns
Leonid Serebreni, L. Pleyer, Vanja Haberle, Oliver Hendy +7 more
2022bioRxiv18 citations Open access
Semantic Scholar
Red blood cell alloimmunization in 184 patients with myeloid neoplasms treated with azacitidine - A retrospective single center experience.
Michael Leisch, L. Weiss, N. Lindlbauer, C. Jungbauer +5 more
2017Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis18 citations Open access
Semantic Scholar
A genome-wide screen identifies silencers with distinct chromatin properties and mechanisms of repression.
Lorena Hofbauer, L. Pleyer, F. Reiter, Alexander Schleiffer +4 more
2024Molecules and Cells14 citations Open access
Semantic Scholar
Health-Related Quality of Life as Assessed by the EQ-5D-5L Predicts Outcomes of Patients Treated with Azacitidine—A Prospective Cohort Study by the AGMT
L. Pleyer, S. Heibl, C. Tinchon, S. Vallet +17 more
2023Cancers14 citations Open access
Semantic Scholar
The Class IIA Histone Deacetylase (HDAC) Inhibitor TMP269 Downregulates Ribosomal Proteins and Has Anti-Proliferative and Pro-Apoptotic Effects on AML Cells
Laura Urwanisch, M. S. Unger, Helene Sieberer, Hieu-Hoa Dang +14 more
2023Cancers14 citations Open access
Semantic Scholar
Fludarabine and rituximab with escalating doses of lenalidomide followed by lenalidomide/rituximab maintenance in previously untreated chronic lymphocytic leukaemia (CLL): the REVLIRIT CLL-5 AGMT phase I/II study
A. Egle, M. Steurer, T. Melchardt, L. Weiss +12 more
2018Annals of Hematology14 citations Open access
Semantic Scholar
Targeting NLRP3 inhibits AML progression by inducing PERK/eIF2-mediated apoptosis
Michela Luciano, Helene Sieberer, P. Krenn, Hieu-Hoa Dang +26 more
2024Cell Communication and Signaling11 citations Open access
Semantic Scholar
Distribution of Curcumin and THC in Peripheral Blood Mononuclear Cells Isolated from Healthy Individuals and Patients with Chronic Lymphocytic Leukemia.
G. Bolger, Albert Licollari, Ai-Min Tan, R. Greil +4 more
2018Anticancer Research11 citations Open access
Semantic Scholar
Scalable Enrichment of Immunomodulatory Human Acute Myeloid Leukemia Cell Line-Derived Extracellular Vesicles
H. Binder, Nicole Maeding, Martin Wolf, A. Cronemberger-Andrade +15 more
2021Cells9 citations Open access
Semantic Scholar
Adverse Events in 1406 Patients Receiving 13,780 Cycles of Azacitidine within the Austrian Registry of Hypomethylating Agents—A Prospective Cohort Study of the AGMT Study-Group
M. Leisch, M. Pfeilstöcker, R. Stauder, S. Heibl +19 more
2022Cancers8 citations Open access
Semantic Scholar
Molecular-Based Ecosystem to Improve Personalized Medicine in Chronic Myelomonocytic Leukemia
L. Lanino, A. Hunter, N. Gagelmann, M. Robin +46 more
2026Journal of Clinical Oncology7 citations Open access
Semantic Scholar
IDO in MDS/AML disease progression and its role in resistance to azacitidine: a potential new drug target?
M. Leisch, R. Greil, L. Pleyer
2020British Journal of Haematology7 citations Open access
Semantic Scholar
Rituximab maintenance overcomes the negative prognostic factor of obesity in CLL: Subgroup analysis of the international randomized AGMT CLL‐8a mabtenance trial
A. Egle, T. Melchardt, P. Obrtlíková, L. Smolej +33 more
2019Cancer Medicine7 citations Open access
Semantic Scholar
Sequential immunotherapy in a patient with primary refractory Hodgkin lymphoma and novel mutations
R. Greil, L. Pleyer, Bettina Jansko, Carmen Feierabend +6 more
2018OncoTarget7 citations Open access
Semantic Scholar
Treatment of aggressive B-cell lymphoma in elderly patients: influence of single nucleotide polymorphisms affecting pharmacodynamics of chemotherapeutics
T. Melchardt, L. Weiss, C. Hufnagl, D. Neureiter +9 more
2015Leukemia and Lymphoma6 citations
Semantic Scholar
Azacitidine in Acute Myeloid Leukemia with >30% Bone Marrow Blasts and <15 G/L White Blood Cell Count: Results from the Austrian Azacitidine Registry of the AGMT Study Group Versus Randomized Controlled Phase III Clinical Trial Data
L. Pleyer, S. Burgstaller, R. Stauder, M. Girschikofsky +18 more
20156 citations
Semantic Scholar
Azacitidine in Patients with Relapsed/Refractory Acute Myeloid Leukemia : Retrospective Analysis of the Austrian Azacitidine Registry
L. Pleyer, S. Burgstaller, R. Stauder, M. Girschikofsky +19 more
20146 citations
Semantic Scholar
Impact of Response to Hypomethylating Agent-Based Therapy on Survival Outcomes in the Context of Baseline Clinical-Molecular Risk and Transplant Status in Patients with Myelodysplastic Syndromes/Neoplasms (MDS): An Analysis from the International Consortium for MDS (icMDS) Validate Database
Benjamin Rolles, J. Bewersdorf, Tariq Kewan, O. Bláha +54 more
2024Blood5 citations
Semantic Scholar
The double-edged sword of (re)expression of genes by hypomethylating agents: from viral mimicry to exploitation as priming agents for targeted immune checkpoint modulation
F. Wolff, M. Leisch, R. Greil, A. Risch +1 more
2017Cell Communication and Signaling5 citations Open access
Semantic Scholar
Cox proportional hazards deep neural network identifies peripheral blood complete remission to be at least equivalent to morphologic complete remission in predicting outcomes of patients treated with azacitidine—A prospective cohort study by the AGMT
L. Pleyer, Marc Vaisband, Manuel Drost, M. Pfeilstöcker +21 more
2023American journal of hematology/oncology4 citations Open access
Semantic Scholar
Effects of the Therapeutic Armamentarium on Survival and Time to Next Treatment in CMML Subtypes: An International Analysis of 950 Cases Coordinated By the AGMT Study Group
L. Pleyer, M. Leisch, A. Kourakli, E. Padron +35 more
2019Blood4 citations Open access
Semantic Scholar

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